BE881675A - B-lactames derives de l'acide penicillanique leur preparation et leurs utilisations therapeutiques - Google Patents

B-lactames derives de l'acide penicillanique leur preparation et leurs utilisations therapeutiques Download PDF

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Publication number
BE881675A
BE881675A BE0/199363A BE199363A BE881675A BE 881675 A BE881675 A BE 881675A BE 0/199363 A BE0/199363 A BE 0/199363A BE 199363 A BE199363 A BE 199363A BE 881675 A BE881675 A BE 881675A
Authority
BE
Belgium
Prior art keywords
emi
preparation
formula
therapeutic uses
aqueous phase
Prior art date
Application number
BE0/199363A
Other languages
English (en)
French (fr)
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of BE881675A publication Critical patent/BE881675A/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D503/00—Heterocyclic compounds containing 4-oxa-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxapenicillins, clavulanic acid derivatives; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
BE0/199363A 1979-02-13 1980-02-12 B-lactames derives de l'acide penicillanique leur preparation et leurs utilisations therapeutiques BE881675A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7905020 1979-02-13

Publications (1)

Publication Number Publication Date
BE881675A true BE881675A (fr) 1980-08-12

Family

ID=10503160

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/199363A BE881675A (fr) 1979-02-13 1980-02-12 B-lactames derives de l'acide penicillanique leur preparation et leurs utilisations therapeutiques

Country Status (4)

Country Link
JP (2) JPS55113790A (el)
KR (1) KR830001903B1 (el)
BE (1) BE881675A (el)
ZA (1) ZA80796B (el)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4309347A (en) 1979-05-16 1982-01-05 Pfizer Inc. Penicillanoyloxymethyl penicillanate 1,1,1',1'-tetraoxide
EP0059046A1 (en) * 1981-02-20 1982-09-01 Pfizer Inc. Bis-esters of alkanediols, pharmaceutical compositions thereof and intermediates therefor
US4420426A (en) 1979-03-05 1983-12-13 Pfizer Inc. 6-Alpha-halopenicillanic acid 1,1-dioxides
US4432970A (en) * 1979-11-23 1984-02-21 Pfizer Inc. 6-beta-Halopenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4444686A (en) * 1982-01-25 1984-04-24 Pfizer Inc. Crystalline penicillin ester intermediate
US4478748A (en) * 1981-02-20 1984-10-23 Pfizer Inc. Bis-esters of alkanediols
US4540687A (en) * 1981-09-09 1985-09-10 Pfizer Inc. Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds
US4582829A (en) * 1981-09-09 1986-04-15 Pfizer Inc. Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds
US4714761A (en) * 1979-03-05 1987-12-22 Pfizer Inc. 6,6-dihalopenicillanic acid 1,1-dioxides and process
US4831025A (en) * 1980-10-31 1989-05-16 Leo Pharmaceutical Products Ltd. Crystalline penicillin derivative tosylate hydrates
US4882325A (en) * 1980-10-06 1989-11-21 Leo Pharmaceutical Products Ltd. A/S Crystalline 1,1-dioxopenicillanoyloxymethyl 6-(d-amino-phenylacetamido)penicillanate napsylate and method of using the same

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4244951A (en) * 1979-05-16 1981-01-13 Pfizer Inc. Bis-esters of methanediol with penicillins and penicillanic acid 1,1-dioxide
IN159362B (el) * 1981-03-23 1987-05-09 Pfizer
US4419284A (en) * 1981-03-23 1983-12-06 Pfizer Inc. Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide
ZA821903B (en) * 1981-03-23 1983-01-26 Pfizer Process for the preparation of penicillanic acid esters
JPS5857384A (ja) * 1981-09-09 1983-04-05 フアイザ−・インコ−ポレ−テツド 抗菌性のペニシラン酸６′‐（２‐アミノ‐２‐〔４‐アシルオキシフェニル〕アセタミド）ペニシラノイルオキシメチル１，１‐ジオキシド化合物
US4351840A (en) * 1981-09-18 1982-09-28 Pfizer Inc. Antibacterial esters of resorcinol with ampicillin and penicillanic acid 1,1-dioxide derivatives
US4359472A (en) * 1981-12-22 1982-11-16 Pfizer Inc. Bis-hydroxymethyl carbonate bridged antibacterial agents
US4432987A (en) * 1982-04-23 1984-02-21 Pfizer Inc. Crystalline benzenesulfonate salts of sultamicillin
PH20068A (en) * 1982-12-06 1986-09-18 Pfizer Process and intermediates for sultamicillin and analogs
US4835674A (en) * 1986-07-28 1989-05-30 Bull Hn Information Systems Inc. Computer network system for multiple processing elements
KR20020028298A (ko) * 2000-10-09 2002-04-17 황해용 초배지 및 그 제조장치
DE102004021281A1 (de) * 2004-04-29 2005-11-24 Boehringer Ingelheim Vetmedica Gmbh Verwendung von Meloxicam-Formulierungen in der Veterinärmedizin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1578128A (en) * 1976-03-30 1980-11-05 Leo Pharm Prod Ltd Amidinopenicillanoyloxyalkyl amoxycillinates

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4420426A (en) 1979-03-05 1983-12-13 Pfizer Inc. 6-Alpha-halopenicillanic acid 1,1-dioxides
US4714761A (en) * 1979-03-05 1987-12-22 Pfizer Inc. 6,6-dihalopenicillanic acid 1,1-dioxides and process
US4309347A (en) 1979-05-16 1982-01-05 Pfizer Inc. Penicillanoyloxymethyl penicillanate 1,1,1',1'-tetraoxide
US4432970A (en) * 1979-11-23 1984-02-21 Pfizer Inc. 6-beta-Halopenicillanic acid 1,1-dioxides as beta-lactamase inhibitors
US4882325A (en) * 1980-10-06 1989-11-21 Leo Pharmaceutical Products Ltd. A/S Crystalline 1,1-dioxopenicillanoyloxymethyl 6-(d-amino-phenylacetamido)penicillanate napsylate and method of using the same
US4831025A (en) * 1980-10-31 1989-05-16 Leo Pharmaceutical Products Ltd. Crystalline penicillin derivative tosylate hydrates
EP0059046A1 (en) * 1981-02-20 1982-09-01 Pfizer Inc. Bis-esters of alkanediols, pharmaceutical compositions thereof and intermediates therefor
US4478748A (en) * 1981-02-20 1984-10-23 Pfizer Inc. Bis-esters of alkanediols
US4540687A (en) * 1981-09-09 1985-09-10 Pfizer Inc. Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds
US4582829A (en) * 1981-09-09 1986-04-15 Pfizer Inc. Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds
US4444686A (en) * 1982-01-25 1984-04-24 Pfizer Inc. Crystalline penicillin ester intermediate

Also Published As

Publication number Publication date
JPS6259709B2 (el) 1987-12-12
JPS62281879A (ja) 1987-12-07
KR830001903B1 (ko) 1983-09-19
JPH0470315B2 (el) 1992-11-10
KR830001947A (ko) 1983-05-21
ZA80796B (en) 1981-02-25
JPS55113790A (en) 1980-09-02

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Legal Events

Date Code Title Description
CCPA Application for a supplementary protection certificate

Free format text: 093C0069

CCPV Grant of a supplementary protection certificate

Free format text: 093C0069, EXPIRES 20020409

RE20 Patent expired

Owner name: LEO PHARMACEUTICAL PRODUCTS LTD A/S (LOVENS KEMIS

Effective date: 20000212