BE879494A - Procede de production de l'oxymorphone - Google Patents

Procede de production de l'oxymorphone

Info

Publication number
BE879494A
BE879494A BE0/197710A BE197710A BE879494A BE 879494 A BE879494 A BE 879494A BE 0/197710 A BE0/197710 A BE 0/197710A BE 197710 A BE197710 A BE 197710A BE 879494 A BE879494 A BE 879494A
Authority
BE
Belgium
Prior art keywords
oxymorphone
production process
production
oxymorphone production
Prior art date
Application number
BE0/197710A
Other languages
English (en)
Inventor
M Wilson
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of BE879494A publication Critical patent/BE879494A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polarising Elements (AREA)
BE0/197710A 1978-10-19 1979-10-18 Procede de production de l'oxymorphone BE879494A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US95305678A 1978-10-19 1978-10-19

Publications (1)

Publication Number Publication Date
BE879494A true BE879494A (fr) 1980-02-15

Family

ID=25493512

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/197710A BE879494A (fr) 1978-10-19 1979-10-18 Procede de production de l'oxymorphone

Country Status (16)

Country Link
JP (1) JPS55501025A (fr)
AU (1) AU5189779A (fr)
BE (1) BE879494A (fr)
CA (1) CA1108132A (fr)
CS (1) CS211364B2 (fr)
DK (1) DK258280A (fr)
ES (1) ES485154A1 (fr)
FI (1) FI793235A (fr)
FR (1) FR2439201A1 (fr)
GB (1) GB2049680A (fr)
IL (1) IL58489A0 (fr)
IT (1) IT7969032A0 (fr)
NL (1) NL7920126A (fr)
NO (1) NO793297L (fr)
SE (1) SE8004454L (fr)
WO (1) WO1980000841A1 (fr)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4795813A (en) * 1981-08-17 1989-01-03 The Florida Board Of Regents On Behalf Of The Florida State University Synthesis of derivatives of codeine and other 3-O-alkylmorphines
US5668285A (en) * 1986-10-31 1997-09-16 The United States Of America As Represented By The Department Of Health And Human Services Total synthesis of northebaine, normophine, noroxymorphone enantiomers and derivatives via N-Nor intermediates
FR2636330B1 (fr) * 1988-09-13 1990-11-30 Sanofi Sa Procede de preparation de derives de morphinane
CA2067200C (fr) * 1989-10-16 1998-06-30 Kenner C. Rice Synthese totale d'enantiomeres de la northebaine, normorphine, noroxymorphone et de leurs derives par des intermediaires n-nor
US8329216B2 (en) 2001-07-06 2012-12-11 Endo Pharmaceuticals Inc. Oxymorphone controlled release formulations
US20030130297A1 (en) 2001-07-06 2003-07-10 Endo Pharmaceuticals, Inc. Oral administration of 6-hydroxy-oxymorphone for use as an analgesic
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
CA2644095A1 (fr) 2006-03-02 2007-09-13 Mallinckrodt Inc. Procedes de preparation de produits a base de morphinan-6-one avec de faibles niveaux de composes de cetones alpha, beta-insaturees
EP2249811A1 (fr) 2008-01-25 2010-11-17 Grünenthal GmbH Forme posologique pharmaceutique
CN102123701B (zh) 2008-05-09 2013-03-27 格吕伦塔尔有限公司 使用喷雾冻凝步骤制备中间粉末制剂以及最终固体剂型的方法
JP2012533585A (ja) 2009-07-22 2012-12-27 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 酸化感受性オピオイドのための不正使用防止剤形
NZ596667A (en) 2009-07-22 2013-09-27 Gruenenthal Chemie Hot-melt extruded controlled release dosage form
KR20130137627A (ko) 2010-09-02 2013-12-17 그뤼넨탈 게엠베하 음이온성 중합체를 포함하는 내변조성 투여형
CA2808219C (fr) 2010-09-02 2019-05-14 Gruenenthal Gmbh Forme pharmaceutique inviolable comportant un sel inorganique
NO2736497T3 (fr) 2011-07-29 2018-01-20
CN103841964A (zh) 2011-07-29 2014-06-04 格吕伦塔尔有限公司 提供药物立即释放的抗破碎片剂
CA2864949A1 (fr) 2012-02-28 2013-09-06 Grunenthal Gmbh Forme pharmaceutique inviolable comprenant un compose pharmacologiquement actif et un polymere anionique
CA2868142A1 (fr) 2012-04-18 2013-10-24 Grunenthal Gmbh Forme pharmaceutique inviolable et resistante a la liberation massive
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
AU2014273226B2 (en) 2013-05-29 2019-06-27 Grunenthal Gmbh Tamper resistant dosage form with bimodal release profile
BR112015026549A2 (pt) 2013-05-29 2017-07-25 Gruenenthal Gmbh forma de dosagem à prova de violação contendo uma ou mais partículas
WO2015004245A1 (fr) 2013-07-12 2015-01-15 Grünenthal GmbH Forme posologique inviolable contenant un polymère d'éthylène-acétate de vinyle
BR112016010482B1 (pt) 2013-11-26 2022-11-16 Grünenthal GmbH Preparação de uma composição farmacêutica em pó por meio de criomoagem
WO2015173195A1 (fr) 2014-05-12 2015-11-19 Grünenthal GmbH Formulation pour capsule à libération immédiate résistant aux manipulations illicites comprenant du tapentadol
AU2015266117A1 (en) 2014-05-26 2016-11-24 Grunenthal Gmbh Multiparticles safeguarded against ethanolic dose-dumping
EP3285745A1 (fr) 2015-04-24 2018-02-28 Grünenthal GmbH Forme galénique inviolable avec libération immédiate et résistance à l'extraction par solvant.
EP3346991A1 (fr) 2015-09-10 2018-07-18 Grünenthal GmbH Protection contre un surdosage par voie orale à l'aide de formulations à libération immédiate dissuasives d'abus
ES2701855T3 (es) 2016-05-31 2019-02-26 Alcaliber Investig Desarrollo E Innovacion Slu Proceso para la obtención de 3,14-diacetiloximorfona a partir de oripavina

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3249616A (en) * 1966-05-03 Ix-dfflydroxy-g-oxo-n-phenethylmor- phinan (cis) and production thereof
US2806033A (en) * 1955-08-03 1957-09-10 Lewenstein Morphine derivative
US3775414A (en) * 1972-05-10 1973-11-27 Bristol Myers Co Process for the preparation of 14-hydroxymorphinan derivatives

Also Published As

Publication number Publication date
SE8004454L (sv) 1980-06-16
CS211364B2 (en) 1982-02-26
AU5189779A (en) 1980-04-24
JPS55501025A (fr) 1980-11-27
IL58489A0 (en) 1980-01-31
ES485154A1 (es) 1980-06-16
GB2049680A (en) 1980-12-31
WO1980000841A1 (fr) 1980-05-01
FR2439201A1 (fr) 1980-05-16
IT7969032A0 (it) 1979-10-18
DK258280A (da) 1980-06-17
FI793235A (fi) 1980-04-20
CA1108132A (fr) 1981-09-01
NO793297L (no) 1980-04-22
NL7920126A (nl) 1980-08-29

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