BE867634A - Composes de la serie des pregnanes avec une fonction oxygene en position 19, procede de preparation et preparations pharmaceutiques qui contiennent ces composes - Google Patents

Composes de la serie des pregnanes avec une fonction oxygene en position 19, procede de preparation et preparations pharmaceutiques qui contiennent ces composes

Info

Publication number
BE867634A
BE867634A BE188175A BE188175A BE867634A BE 867634 A BE867634 A BE 867634A BE 188175 A BE188175 A BE 188175A BE 188175 A BE188175 A BE 188175A BE 867634 A BE867634 A BE 867634A
Authority
BE
Belgium
Prior art keywords
compounds
pregnanes
contain
series
preparation
Prior art date
Application number
BE188175A
Other languages
English (en)
French (fr)
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of BE867634A publication Critical patent/BE867634A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/003Normal steroids containing one or more sulfur atoms not belonging to a hetero ring the S atom directly linked to a ring carbon atom of the cyclopenta(a)hydrophenanthrene skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J33/00Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J33/005Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
    • C07J33/007Cyclic thioketals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0094Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0015Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
BE188175A 1977-05-31 1978-05-30 Composes de la serie des pregnanes avec une fonction oxygene en position 19, procede de preparation et preparations pharmaceutiques qui contiennent ces composes BE867634A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU77457A LU77457A1 (nl) 1977-05-31 1977-05-31

Publications (1)

Publication Number Publication Date
BE867634A true BE867634A (fr) 1978-11-30

Family

ID=19728591

Family Applications (1)

Application Number Title Priority Date Filing Date
BE188175A BE867634A (fr) 1977-05-31 1978-05-30 Composes de la serie des pregnanes avec une fonction oxygene en position 19, procede de preparation et preparations pharmaceutiques qui contiennent ces composes

Country Status (27)

Country Link
US (1) US4309423A (nl)
JP (1) JPS53149964A (nl)
AT (1) AT365609B (nl)
AU (1) AU520330B2 (nl)
BE (1) BE867634A (nl)
CA (1) CA1114367A (nl)
DD (1) DD140146A5 (nl)
DE (1) DE2823239A1 (nl)
DK (1) DK240078A (nl)
ES (5) ES470282A1 (nl)
FI (1) FI781628A (nl)
FR (3) FR2405712A1 (nl)
GB (1) GB1603675A (nl)
GR (1) GR71594B (nl)
HU (1) HU181861B (nl)
IL (1) IL54805A (nl)
IT (1) IT7849581A0 (nl)
LU (1) LU77457A1 (nl)
NL (1) NL7805632A (nl)
NO (1) NO781884L (nl)
NZ (1) NZ187431A (nl)
PH (1) PH14606A (nl)
PL (1) PL207237A1 (nl)
PT (1) PT68095A (nl)
SE (1) SE7806244L (nl)
SU (1) SU786906A3 (nl)
ZA (1) ZA783125B (nl)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0005758A1 (de) * 1978-05-26 1979-12-12 Ciba-Geigy Ag Verfahren zum Aufbau der Hydroxyacetyl-Seitenkette von Steroiden des Pregnan-Typs, neue 21-Hydroxy-20-oxo-17alpha-pregnan-Verbindungen und pharmazeutische Präparate enthaltend dieselben

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261985A (en) * 1978-11-22 1981-04-14 Ciba-Geigy Corporation Novel diuretics
US5002940A (en) * 1984-11-06 1991-03-26 Ciba-Geigy Corporation Solid drug formulations and stable suspensions
US4659704A (en) * 1985-05-21 1987-04-21 Ramot University Authority For Applied Research & Industrial Development Ltd. 19-hydroxyaldosterone and its preparation
FR2656309B1 (fr) * 1989-12-22 1992-05-07 Roussel Uclaf Nouveaux produits sterouides comportant en position 10, un radical ethyle substitue, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
FR2676740B1 (fr) * 1991-05-23 1993-11-05 Roussel Uclaf Nouveaux derives sterouides du pregna-4,9(11),17(20)-trie-3-one, leur preparation, leur application a la preparation de composes sterouides de type pregna-4,9(11),16-triene-3,20-dione et nouveaux intermediaires.
DE4433374A1 (de) * 1994-09-20 1996-03-21 Hoechst Ag 17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
AU2002218179B2 (en) * 2000-09-18 2006-11-16 Merck Serono Sa Method for the preparation of 21-hydroxy-6,19-oxidoprogesterone (21oh-6op)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1146651B (de) * 1956-07-28 1963-04-04 Giuseppe Giusi Vorschub-Schaltgetriebe fuer Maschinen zum Ausschneiden von runden Scheiben aus Kunststoffplatten, insbesondere Knopfrondellen
US3039926A (en) * 1958-10-10 1962-06-19 Pfizer & Co C 19-hydroxy pregnenes
CH425774A (de) * 1961-07-14 1966-12-15 Ciba Geigy Verfahren zur Herstellung von 19-Nor-steroiden
GB1041534A (en) * 1963-04-24 1966-09-07 Merck & Co Inc 20-spiroxane compounds
US3493564A (en) * 1968-02-29 1970-02-03 American Home Prod 2,19-epoxy-delta**4,6-steroids and intermediates for their synthesis
BR6915132D0 (pt) * 1969-04-02 1973-02-08 Ciba Geigy Processo para a obtencao de delta 4 6-ou delta 5(10) 6-3-oxo-19-nor-esteroides
US3849404A (en) * 1973-03-09 1974-11-19 Searle & Co Purification of 6,7-dihydro-17-hydroxy-3-oxo-3'h-cyclopropa(6,7)-17alpha-pregna-4,6-diene-21-carboxylic acid gamma-lactones
CA1049498A (en) * 1973-11-29 1979-02-27 Gunther Kruger Steroid compounds and processes therefor
JPS53116361A (en) * 1977-03-17 1978-10-11 Mitsubishi Chem Ind Ltd Preparation of 7 acylthioo44enee33oxosteroid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0005758A1 (de) * 1978-05-26 1979-12-12 Ciba-Geigy Ag Verfahren zum Aufbau der Hydroxyacetyl-Seitenkette von Steroiden des Pregnan-Typs, neue 21-Hydroxy-20-oxo-17alpha-pregnan-Verbindungen und pharmazeutische Präparate enthaltend dieselben

Also Published As

Publication number Publication date
FR2405712B1 (nl) 1982-09-10
ZA783125B (en) 1979-06-27
IL54805A0 (en) 1978-07-31
CA1114367A (en) 1981-12-15
IL54805A (en) 1982-11-30
FR2405958B1 (nl) 1982-01-15
FI781628A (fi) 1978-12-01
SU786906A3 (ru) 1980-12-07
PH14606A (en) 1981-10-02
PT68095A (de) 1978-06-01
DE2823239A1 (de) 1978-12-14
AT365609B (de) 1982-02-10
LU77457A1 (nl) 1979-01-19
NZ187431A (en) 1980-05-27
FR2405712A1 (fr) 1979-05-11
FR2408623B1 (nl) 1982-03-05
ES478127A1 (es) 1979-05-16
US4309423A (en) 1982-01-05
NL7805632A (nl) 1978-12-04
GB1603675A (en) 1981-11-25
FR2408623A1 (fr) 1979-06-08
SE7806244L (sv) 1978-12-01
ES478128A1 (es) 1979-05-16
ATA393178A (de) 1981-06-15
ES470282A1 (es) 1979-09-16
ES478125A1 (es) 1979-05-16
AU3665078A (en) 1979-12-06
ES478126A1 (es) 1979-05-16
AU520330B2 (en) 1982-01-28
PL207237A1 (pl) 1979-06-04
DD140146A5 (de) 1980-02-13
JPS53149964A (en) 1978-12-27
NO781884L (no) 1978-12-01
GR71594B (nl) 1983-06-17
IT7849581A0 (it) 1978-05-29
HU181861B (en) 1983-11-28
FR2405958A1 (fr) 1979-05-11
DK240078A (da) 1978-12-01

Similar Documents

Publication Publication Date Title
IT7928464A0 (it) Composizione farmaceutica avente attivita' antitumorale.
IT7928417A0 (it) Composizioni farmaceutiche con esaltazione dell'attivita'terapeutica di cortisonici.
IT7927614A0 (it) 1,2,4,5-tetra-alchil-4-arilpiperidi ne e relative formulazioni farmaceutiche.
BE867634A (fr) Composes de la serie des pregnanes avec une fonction oxygene en position 19, procede de preparation et preparations pharmaceutiques qui contiennent ces composes
DZ452A1 (fr) Formulations pharmaceutiques comprenant de l'insuline humaine et du c-paptide humain.
NL192741B (nl) Oxazafosforin-4-thioalkaanzuurverbindingen en farmaceutisch preparaat met antineoplastische eigenschappen.
BE856395A (fr) La 2-bromo-6-fluoro-n-2-imidazolinylidene-benzamine, ses sels d'addition avec des acides, procedes pour leur preparation et les medicaments les renfermant.
NL172157C (nl) Preparaat met bloeddrukverlagende werking en de daarvoor geschikte werkzame verbindingen.
NL187577C (nl) 3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen.
DE2862059D1 (en) Thiazolidinedione-2,4 derivatives, their preparation and pharmaceutical applications
NL190071C (nl) 4-oxo-pyrimido-(2,1-a)-isochinoline-derivaat met een anti-allergische activiteit, werkwijze ter bereiding daarvan en farmaceutisch preparaat daaruit vervaardigd.
FR2505826B1 (fr) Derives d'isoprenylamine et compositions pharmaceutiques preparees avec ces derives
JPS5553209A (en) Agricultural drug* its mamufacture and its use
IT7920398A0 (it) Derivato ad attivita' analgesica antiinfiammatoria potenziata eprocedimento per la sua preparazione.
LU81182A1 (fr) Nouveaux derives de l'isoquinoleine,leur preparation et les compositions pharmaceutiques qui les contiennent
IT8247807A0 (it) 2,1,3-benzotiadiazoli e 2,1,3,-benzossadiazoli, loro preparazione e loro applicazione come medicamenti
IT7824578A0 (it) Composizione farmaceutica per la terapia di stati di frigidita' ed impotenza.
IL56494A (en) 17 alpha-alkoxyalkoxy steroids of the pregnane series,their preparation and pharmaceutical compositions containing them
ZA765990B (en) 0,0-diethyl-0-(n-methoxy-2-nitrobenzimidoyl)-thiono-phosphoric acid ester process for its preparation and its use asan insecticide and acaricide
NL190120C (nl) 2,3-dihydro-4h-1-benzopyran-4-on-0-carbamoyloximen alsmede farmaceutisch preparaat daarvan.
BE858795A (fr) Nouveaux 2,2-dimethyl 19-nor steroides procede de preparation et compositions pharmaceutiques
ZA795029B (en) New 0-chloro-2-benzoyl-4-chloroglycycl anilide derivatives,the preparation thereof and the use thereof as medicaments
Millikan Analysis of the Banff Centre administration
Hallschmid Intrinsic motivation: the effects of task choice, reward magnitude and reward choice
IT7828537A0 (it) 1. 4-idro-piridazine 1-n-sostituite, procedimento per la loro preparazione e loro impiegocome prodotti medicinali.

Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: CIBA-GEIGY A.G.

Effective date: 19840530