BE865406A - Derives 3'-oxygenes des 4'-desoxy vlb "a" et "b" et des derives 1-formyles apparentes, et leur utilisation comme medicaments - Google Patents

Derives 3'-oxygenes des 4'-desoxy vlb "a" et "b" et des derives 1-formyles apparentes, et leur utilisation comme medicaments

Info

Publication number
BE865406A
BE865406A BE1008790A BE1008790A BE865406A BE 865406 A BE865406 A BE 865406A BE 1008790 A BE1008790 A BE 1008790A BE 1008790 A BE1008790 A BE 1008790A BE 865406 A BE865406 A BE 865406A
Authority
BE
Belgium
Prior art keywords
derivatives
formyle
desoxy
vlb
medicinal products
Prior art date
Application number
BE1008790A
Other languages
English (en)
French (fr)
Inventor
G L Thompson
G C Paschal
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BE865406A publication Critical patent/BE865406A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
BE1008790A 1977-03-30 1978-03-29 Derives 3'-oxygenes des 4'-desoxy vlb "a" et "b" et des derives 1-formyles apparentes, et leur utilisation comme medicaments BE865406A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/782,644 US4115388A (en) 1977-03-30 1977-03-30 3'-Oxygenated derivatives of 4'-deoxy VLB "A" and "B" and related 1-formyl compounds

Publications (1)

Publication Number Publication Date
BE865406A true BE865406A (fr) 1978-09-29

Family

ID=25126725

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1008790A BE865406A (fr) 1977-03-30 1978-03-29 Derives 3'-oxygenes des 4'-desoxy vlb "a" et "b" et des derives 1-formyles apparentes, et leur utilisation comme medicaments

Country Status (14)

Country Link
US (1) US4115388A (xx)
JP (1) JPS53130699A (xx)
AR (1) AR224342A1 (xx)
BE (1) BE865406A (xx)
CA (1) CA1097628A (xx)
CH (1) CH634849A5 (xx)
DE (1) DE2813286A1 (xx)
FR (1) FR2385724A1 (xx)
GB (1) GB1596235A (xx)
HU (1) HU182482B (xx)
IE (1) IE46692B1 (xx)
IL (1) IL54357A (xx)
IT (1) IT1096161B (xx)
NL (1) NL7803253A (xx)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4166810A (en) * 1978-04-20 1979-09-04 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide
US4199504A (en) * 1978-05-15 1980-04-22 Eli Lilly And Company Bridged cathranthus alkaloid dimers
HU185691B (en) * 1982-02-09 1985-03-28 Richter Gedeon Vegyeszet Process for preparing a new analgetic pharmaceutical composition
US4897477A (en) * 1985-03-12 1990-01-30 University Of Vermont & State Agricultural College Synthesis of vinblastine and vincristine type compounds
US4841045A (en) * 1985-03-12 1989-06-20 University Of Vermont & State Agricultural College Synthesis of vinblastine and vincristine type compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3352868A (en) * 1964-04-01 1967-11-14 Lilly Co Eli Dihydrovinblastine
US3887565A (en) * 1974-05-06 1975-06-03 Lilly Co Eli Vincadioline
FR2296418B1 (xx) * 1974-12-30 1978-07-21 Anvar
US3944554A (en) * 1975-01-09 1976-03-16 Eli Lilly And Company 4-Desacetoxy-3-hydroxyvinblastine

Also Published As

Publication number Publication date
US4115388A (en) 1978-09-19
IL54357A0 (en) 1978-06-15
IL54357A (en) 1982-11-30
GB1596235A (en) 1981-08-19
CA1097628A (en) 1981-03-17
IT1096161B (it) 1985-08-17
IE780610L (en) 1978-09-30
FR2385724B1 (xx) 1981-03-06
AR224342A1 (es) 1981-11-30
CH634849A5 (de) 1983-02-28
DE2813286A1 (de) 1978-10-05
HU182482B (en) 1984-01-30
FR2385724A1 (fr) 1978-10-27
IE46692B1 (en) 1983-08-24
IT7821726A0 (it) 1978-03-29
NL7803253A (nl) 1978-10-03
JPS53130699A (en) 1978-11-14

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: ELI LILLY AND CY

Effective date: 19840329