BE856860A - Procede de preparation de derives d'androstan-17-one, produits obtenus et leur utilisation - Google Patents

Procede de preparation de derives d'androstan-17-one, produits obtenus et leur utilisation

Info

Publication number: BE856860A
Authority: BE; Belgium
Prior art keywords: androstan; derivatives; preparing; products obtained; products
Prior art date: 1976-07-16

Application number

BE179384A

Other languages

English (en)

French (fr)

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-07-16

Filing date

1977-07-15

Publication date

1978-01-16

1977-07-15 Application filed by Schering Ag filed Critical Schering Ag

1978-01-16 Publication of BE856860A publication Critical patent/BE856860A/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P33/00—Preparation of steroids
- C12P33/005—Degradation of the lateral chains at position 17
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
- C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/0037—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being a saturated hydrocarbon group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/863—Mycobacterium

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Chemical Kinetics & Catalysis (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Steroid Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

BE179384A 1976-07-16 1977-07-15 Procede de preparation de derives d'androstan-17-one, produits obtenus et leur utilisation BE856860A (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19762632677 DE2632677A1 (de)	1976-07-16	1976-07-16	Verfahren zur herstellung von androstan-17-on-derivaten und deren verwendung

Publications (1)

Publication Number	Publication Date
BE856860A true BE856860A (fr)	1978-01-16

Family

ID=5983514

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE179384A BE856860A (fr)	1976-07-16	1977-07-15	Procede de preparation de derives d'androstan-17-one, produits obtenus et leur utilisation

Country Status (18)

Country	Link
US (1)	US4179336A (ru)
JP (1)	JPS5315493A (ru)
AT (1)	AT363196B (ru)
BE (1)	BE856860A (ru)
CH (3)	CH627190A5 (ru)
CS (1)	CS200517B2 (ru)
DD (4)	DD136142A5 (ru)
DE (1)	DE2632677A1 (ru)
DK (1)	DK142372C (ru)
FR (4)	FR2365588A1 (ru)
GB (1)	GB1585786A (ru)
HU (4)	HU182790B (ru)
IE (1)	IE45304B1 (ru)
IT (1)	IT1077339B (ru)
NL (1)	NL7706638A (ru)
SE (1)	SE440779B (ru)
SU (1)	SU980628A3 (ru)
YU (1)	YU164277A (ru)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55148083A (en) *	1979-05-04	1980-11-18	Mitsubishi Chem Ind Ltd	Microorganism
JPS55150893A (en) *	1979-05-11	1980-11-25	Mitsubishi Chem Ind Ltd	Novel microorganism
JPS578794A (en) *	1980-06-17	1982-01-18	Mitsubishi Chem Ind Ltd	Preparation of androstane-type steroid
US4755463A (en) *	1982-05-25	1988-07-05	Wisconsin Alumni Research Foundation	Process for preparing steroids
US4444884A (en) *	1982-05-25	1984-04-24	Wisconsin Alumni Research Foundation	Process for preparing steroids
JPH0512528Y2 (ru) *	1987-09-08	1993-03-31
DE69621281T2 (de) *	1995-02-28	2002-12-05	Nippon Shokubai Co., Ltd.	Acryl-Säure-Derivate, Verfahren zur Herstellung von Acryl-Säure-Derivaten und Acryl-Säure-Polymere
KR101128320B1 (ko) *	2003-05-23	2012-04-12	넥타르 테라퓨틱스	아미도카르보네이트 연결기를 갖는 ｐｅｇ 유도체
JP5701308B2 (ja) *	2009-10-29	2015-04-15	インダストリー−アカデミックコーポレーションファウンデーション，ヨンセイユニバーシティ	新規血管漏出遮断剤
US9388210B2 (en)	2011-02-25	2016-07-12	Washington University	Neuroactive 17(20)-Z-vinylcyano-substituted steroids, prodrugs thereof, and methods of treatment using same
US20150291654A1 (en)	2011-10-14	2015-10-15	Sage Therapeutics, Inc.	3,3 disubstituted 19-nor pregnane compounds, compositions, and uses thereof
EP3392260B1 (en)	2012-12-18	2022-09-21	Washington University	Neuroactive 19-alkoxy-17-substituted steroids, useful in methods of treatment
WO2014127201A1 (en) *	2013-02-15	2014-08-21	Washington University	Neuroactive enantiomeric 15-, 16- and 17-substituted steroids as modulators for gaba type-a receptors
US9512170B2 (en)	2013-03-01	2016-12-06	Washington University	Neuroactive 13, 17-substituted steroids as modulators for GABA type-A receptors
US9365502B2 (en)	2013-03-11	2016-06-14	Washington University	Neuroactive substituted cyclopenta[b]phenanthrenes as modulators for GABA type-A receptors
US9562026B2 (en)	2013-03-14	2017-02-07	Washington University	Neuroactive substituted cyclopent[a]anthracenes as modulators for GABA type-A receptors
WO2014169836A1 (en)	2013-04-17	2014-10-23	Sage Therapeutics, Inc.	19-nor neuroactive steroids and methods of use thereof
PT3498725T (pt)	2013-04-17	2021-09-09	Sage Therapeutics Inc	Esteroides c21-n-pirazolilo 19-nor c3,3-dissubstituídos para uso em terapia
US9725481B2 (en)	2013-04-17	2017-08-08	Sage Therapeutics, Inc.	19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
SI2986624T1 (sl)	2013-04-17	2020-10-30	Sage Therapeutics, Inc.	19-nor nevroaktivni steroidi za metode zdravljenja
CA2918735C (en)	2013-07-19	2023-08-01	Sage Therapeutics, Inc.	Neuroactive steroids, compositions, and uses thereof
PL3488852T3 (pl)	2013-08-23	2021-06-28	Sage Therapeutics, Inc.	Neuroaktywne steroidy, kompozycje i ich zastosowania
US10246482B2 (en)	2014-06-18	2019-04-02	Sage Therapeutics, Inc.	Neuroactive steroids, compositions, and uses thereof
US20170233433A1 (en)	2014-10-16	2017-08-17	Sage Therapeutics, Inc.	Compositions and methods for treating cns disorders
RU2020131091A (ru)	2014-10-16	2020-11-23	Сейдж Терапьютикс, Инк.	Композиции и способы для лечения расстройств цнс
HUE049014T2 (hu)	2014-11-27	2020-09-28	Sage Therapeutics Inc	Készítmények és módszerek a központi idegrendszer rendellenességeinek kezelésére
EP3250210B1 (en)	2015-01-26	2020-12-02	Sage Therapeutics, Inc.	Compositions and methods for treating cns disorders
EP3258939B1 (en)	2015-02-20	2022-09-07	Sage Therapeutics, Inc.	Neuroactive steroids, compositions, and uses thereof
IL264129B2 (en)	2016-07-11	2024-05-01	Sage Therapeutics Inc	C20, C17 and C21 converted neuroactive steroids and methods of using them
EP3481844B1 (en)	2016-07-11	2024-04-17	Sage Therapeutics, Inc.	C7, c12, and c16 substituted neuroactive steroids and their methods of use
EP3976628A1 (en)	2019-05-31	2022-04-06	Sage Therapeutics, Inc.	Neuroactive steroids and compositions thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3451892A (en) *	1965-10-19	1969-06-24	Schering Corp	Process for the preparation of steroidal compounds
NL6705450A (ru) *	1965-10-22	1968-10-21
US3684657A (en) *	1970-05-11	1972-08-15	Searle & Co	Selective microbiological degradation of steroidal 17-alkyls
US3759791A (en) *	1970-12-10	1973-09-18	Searle & Co	Selective microbiological preparation of androst-4-ene-3,17-dione
US3738983A (en) *	1971-08-06	1973-06-12	Searle & Co	Process for the preparation of 3-(3beta,17beta-dihydroxyandrost-5-en-17alpha-yl) propionic acid gamma-lactone
DE2534911C2 (de) *	1975-08-01	1985-04-18	Schering AG, 1000 Berlin und 4709 Bergkamen	Verfahren zur Herstellung von 5-Androsten-17-on-Derivaten

1976
- 1976-07-16 DE DE19762632677 patent/DE2632677A1/de active Granted
1977
- 1977-06-16 NL NL7706638A patent/NL7706638A/xx not_active Application Discontinuation
- 1977-07-01 YU YU01642/77A patent/YU164277A/xx unknown
- 1977-07-06 US US05/813,391 patent/US4179336A/en not_active Expired - Lifetime
- 1977-07-12 CH CH861377A patent/CH627190A5/de not_active IP Right Cessation
- 1977-07-13 IE IE1456/77A patent/IE45304B1/en unknown
- 1977-07-13 AT AT0504677A patent/AT363196B/de not_active IP Right Cessation
- 1977-07-13 CS CS774682A patent/CS200517B2/cs unknown
- 1977-07-14 SE SE7708192A patent/SE440779B/xx not_active IP Right Cessation
- 1977-07-14 DD DD77206207A patent/DD136142A5/xx unknown
- 1977-07-14 DD DD77206205A patent/DD136141A5/xx unknown
- 1977-07-14 DD DD7700200065A patent/DD132439A5/xx not_active IP Right Cessation
- 1977-07-14 DD DD77206210A patent/DD137235A5/xx unknown
- 1977-07-15 BE BE179384A patent/BE856860A/xx not_active IP Right Cessation
- 1977-07-15 JP JP8493277A patent/JPS5315493A/ja active Granted
- 1977-07-15 HU HU8019A patent/HU182790B/hu unknown
- 1977-07-15 DK DK323677A patent/DK142372C/da not_active IP Right Cessation
- 1977-07-15 HU HU8020A patent/HU182681B/hu unknown
- 1977-07-15 IT IT25807/77A patent/IT1077339B/it active
- 1977-07-15 SU SU772502698A patent/SU980628A3/ru active
- 1977-07-15 GB GB29800/77A patent/GB1585786A/en not_active Expired
- 1977-07-15 HU HU77SCHE614A patent/HU179344B/hu not_active IP Right Cessation
- 1977-07-15 HU HU8018A patent/HU182789B/hu unknown
- 1977-07-18 FR FR7721932A patent/FR2365588A1/fr active Granted
1978
- 1978-03-07 FR FR7806457A patent/FR2372176A1/fr active Pending
- 1978-03-07 FR FR7806456A patent/FR2372174A1/fr active Pending
- 1978-03-07 FR FR7806455A patent/FR2372175A1/fr active Pending
1981
- 1981-06-23 CH CH415381A patent/CH629503A5/de not_active IP Right Cessation
- 1981-06-23 CH CH415281A patent/CH629222A5/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
DE2632677C2 (ru)	1988-06-16
FR2365588B1 (ru)	1982-06-25
GB1585786A (en)	1981-03-11
HU182681B (en)	1984-02-28
CH629222A5 (de)	1982-04-15
FR2372175A1 (fr)	1978-06-23
DD132439A5 (de)	1978-09-27
SE440779B (sv)	1985-08-19
JPS6117477B2 (ru)	1986-05-07
DK323677A (da)	1978-01-17
HU182790B (en)	1984-03-28
HU182789B (en)	1984-03-28
YU164277A (en)	1982-08-31
IT1077339B (it)	1985-05-04
DK142372B (da)	1980-10-20
DE2632677A1 (de)	1978-01-26
CS200517B2 (en)	1980-09-15
IE45304L (en)	1978-01-16
US4179336A (en)	1979-12-18
JPS5315493A (en)	1978-02-13
AT363196B (de)	1981-07-10
DD136141A5 (de)	1979-06-20
FR2365588A1 (fr)	1978-04-21
NL7706638A (nl)	1978-01-18
HU179344B (en)	1982-10-28
SU980628A3 (ru)	1982-12-07
FR2372174A1 (fr)	1978-06-23
ATA504677A (de)	1980-12-15
DK142372C (da)	1981-03-23
FR2372176A1 (fr)	1978-06-23
DD137235A5 (de)	1979-08-22
CH627190A5 (ru)	1981-12-31
SE7708192L (sv)	1978-01-17
IE45304B1 (en)	1982-07-28
DD136142A5 (de)	1979-06-20
CH629503A5 (de)	1982-04-30

Legal Events

Date

Code

Title

Description

1993-01-31

RE

Patent lapsed

Owner name: SCHERING A.G.

Effective date: 19920731

Publication	Publication Date	Title
BE856860A (fr)	1978-01-16	Procede de preparation de derives d'androstan-17-one, produits obtenus et leur utilisation
BE860971A (fr)	1978-05-18	Procede de preparation de n,n'-methylenebis-(0,0-diaryl n-phosphonomethylglycinonitriles, nouveaux produits ainsi obtenus et leur utilisation
FR2349579A1 (fr)	1977-11-25	Derives de 1,2-dihydronaphtalene et leur procede de preparation
BE828430A (fr)	1975-10-27	Phenylalcoylamines, leur procede d'obtention et leur application commemedicaments
BE843248A (fr)	1976-12-22	Procede de preparation de phtalonitrile, et produit obtenu
FR2287435A1 (fr)	1976-05-07	Procede de preparation de cyclohexane-diones-1,3 et d'alkyl-6-dihydro-3,4-pyranones-2
FR2335522A1 (fr)	1977-07-15	Procede de preparation d'androstene-4 diones-3,17
IL51974A0 (en)	1977-06-30	New 1,4-benzodioxane derivatives process for preparing them and pharmaceutical compositions
FR2309514A1 (fr)	1976-11-26	Procede de preparation d'acetoacetyl-arylamides
BE855236A (fr)	1977-11-30	Derives omega-nor-aromatiques de 13,14-dehydro-prostaglandines et procede pour leur preparation
LU80346A1 (fr)	1979-03-16	Procede de preparation d'un produit alimentaire ameliore
IT1146228B (it)	1986-11-12	Procedimento per preparare 2,6-dialchil-n-alcossimetil-2-cloro-acetanilidi e prodotto ottenuto
FR2315273A1 (fr)	1977-01-21	Procede de preparation d'indoloquinolizines
BE855371A (fr)	1977-10-03	Procede de preparation de 1,1-difluorethylene
FR2333805A1 (fr)	1977-07-01	Procede de preparation de n,n'-bis-trimethylsilyluree
FR2299329A1 (fr)	1976-08-27	Procede de preparation de 1,2-benzisothiazoles
BE841471A (fr)	1976-09-01	Procede de preparation d'humulone et produit obtenu
BE852700R (fr)	1977-09-21	Procede de preparation d'oxaphospholannes-1,2
BE866588A (fr)	1978-10-30	Derives de 2-benzyl-perhydroazepines, procede pour leur preparation et application comme medicaments
FR2310998A1 (fr)	1976-12-10	Procede de preparation de la 2,5-dimethoxy-4-chloraniline
FR2307781A1 (fr)	1976-11-12	Procede de preparation d'acenaphtenes
BE848627A (fr)	1977-05-23	Derives substitues d'aminobenzaldehydes et leur procede de preparation,
BE858387A (fr)	1978-03-02	Procede pour la preparation de 2,3-cycloalkenopyridines et produits obtenus
BE841577A (fr)	1976-11-08	Procede de preparation de derives de 21-hydroxy-16-pregnen-20-one, et produits obtenus
FR2334654A1 (fr)	1977-07-08	Procede de preparation d'halogeno-nitrobenzenes