BE791544A - Preparation d'esters alkyliques de dipeptide - Google Patents
Preparation d'esters alkyliques de dipeptideInfo
- Publication number
- BE791544A BE791544A BE791544DA BE791544A BE 791544 A BE791544 A BE 791544A BE 791544D A BE791544D A BE 791544DA BE 791544 A BE791544 A BE 791544A
- Authority
- BE
- Belgium
- Prior art keywords
- dipeptide
- preparation
- alkyl esters
- esters
- alkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/66—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
- A23L27/30—Artificial sweetening agents
- A23L27/31—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives
- A23L27/32—Artificial sweetening agents containing amino acids, nucleotides, peptides or derivatives containing dipeptides or derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/801—Peptide sweetners
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Polymers & Plastics (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NLAANVRAGE7115944,A NL172324C (nl) | 1971-11-19 | 1971-11-19 | Werkwijze voor het bereiden van asparagyl-aminozuur-alkylesters met 1-6 koolstofatomen in de alkylgroep door reactie van een n-beschermd asparaginezuuranhydride met een zout van een alkylester van een aminozuur. |
Publications (1)
Publication Number | Publication Date |
---|---|
BE791544A true BE791544A (fr) | 1973-05-17 |
Family
ID=19814512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE791544D BE791544A (fr) | 1971-11-19 | Preparation d'esters alkyliques de dipeptide |
Country Status (12)
Country | Link |
---|---|
US (1) | US3879372A (fr) |
JP (1) | JPS5417727B2 (fr) |
BE (1) | BE791544A (fr) |
CA (1) | CA1003408A (fr) |
CH (1) | CH584188A5 (fr) |
DE (1) | DE2256055C2 (fr) |
DK (1) | DK149126C (fr) |
FR (1) | FR2160471B1 (fr) |
GB (1) | GB1359123A (fr) |
IT (1) | IT982394B (fr) |
NL (1) | NL172324C (fr) |
SE (1) | SE393603B (fr) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0035047B1 (fr) * | 1980-03-03 | 1984-01-25 | Ajinomoto Co., Inc. | Procédé pour la préparation d'un ester alkylique inférieur de l'alpha-L-aspartyl-L-phénylalanine et intermédiaire pour cette préparation |
US4333872A (en) * | 1980-05-27 | 1982-06-08 | Chimicasa Gmbh | Method of producing α-L-aspartyl-L-phenylalanine methylester |
NL8005006A (nl) * | 1980-09-04 | 1982-04-01 | Stamicarbon | Dipeptide-zoetstof. |
JPS57131746A (en) * | 1981-02-10 | 1982-08-14 | Ajinomoto Co Inc | Removal of n-formyl group |
IE810577L (en) * | 1983-05-31 | 1982-09-16 | Prendergast Angela | Apparatus for fermentation |
FR2516077A1 (fr) * | 1981-11-06 | 1983-05-13 | Human Pharm Sa Laboratoires | Procede de preparation de l'ester-methylique de l'a-aspartyl phenylalanine |
JPS58185545A (ja) * | 1982-04-22 | 1983-10-29 | Ajinomoto Co Inc | α−L−アスパルチル−L−フエニルアラニンメチルエステルまたはその塩酸塩の製法 |
IT1152488B (it) * | 1982-08-06 | 1986-12-31 | Pierrel Spa | Procedimento per la preparazione dell'anidride dell'acido n-formil-l-aspartico |
IT1155060B (it) * | 1982-09-02 | 1987-01-21 | Sirac Srl | Procedimento per la preparazione di esteri alchilici della alfa-l-aspartil-l-fenilalanina |
US4555362A (en) * | 1983-06-20 | 1985-11-26 | G. D. Searle & Co. | Method and intermediates for producing α-L-aspartyl-L-phenylalanine |
GB8321802D0 (en) * | 1983-08-12 | 1983-09-14 | Erba Farmitalia | Aspartame synthesis |
JPS6075497A (ja) * | 1983-09-30 | 1985-04-27 | Ajinomoto Co Inc | Ν−保護−α−L−アスパルチル−L−フェニルアラニンメチルエステルの製造法 |
JPS60164495A (ja) * | 1984-01-16 | 1985-08-27 | モンサント コンパニー | N‐ホルミルアミノ酸とペプチド残基の酵素的結合法 |
FR2558471B1 (fr) * | 1984-01-19 | 1987-11-20 | Isochem Sa | Procede de preparation d'aspartyl peptides, et nouveaux intermediaires de synthese |
JPH07636B2 (ja) * | 1984-12-17 | 1995-01-11 | 三井東圧化学株式会社 | N−ホルミル−α−アスパルチルフエニルアラニンの製造法 |
JPS61148198A (ja) * | 1984-12-22 | 1986-07-05 | Ajinomoto Co Inc | 新規トリペプチド化合物および甘味剤 |
CA1277098C (fr) * | 1984-12-27 | 1990-11-27 | Mitsui Toatsu Chemicals, Inc. | Procede pour la preparation de l'ester methylique de l' -l-aspartyl-l-phenylalanine |
JPH0680074B2 (ja) * | 1985-07-01 | 1994-10-12 | 味の素株式会社 | N―ホルミル―L―α―アスパルチル―L―フェニルアラニンの製法 |
AU561384B2 (en) * | 1985-03-26 | 1987-05-07 | Mitsui Toatsu Chemicals Inc. | Preparation of -l-aspartyl-l-phenylalanine methyl ester or hydrochloride thereof |
US4677220A (en) * | 1985-10-31 | 1987-06-30 | Monsanto Company | Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester |
US4730076A (en) * | 1985-12-18 | 1988-03-08 | Nippon Kayaku Kabushiki Kaisha | Process for producing α-aspartyl-phenylalanine ester |
ES2042583T3 (es) * | 1986-12-05 | 1993-12-16 | Mitsui Toatsu Chemicals | Preparacion de metil ester de alpha-l-aspartil-l-fenil-alanina o uno de sus hidrohaluros. |
JPH0832719B2 (ja) * | 1986-12-19 | 1996-03-29 | 三井東圧化学株式会社 | 吸湿性の小さいα−L−アスパルチル−L−フエニルアラニンメチルエステルの製造法 |
US4774027A (en) * | 1987-11-13 | 1988-09-27 | General Foods Corporation | Process for the preparation of N-L-aminodicarboxylic acid esters and new compositions used in the preparation thereof |
US5017690A (en) * | 1989-08-11 | 1991-05-21 | W. R. Grace & Co.-Conn. | Deblocking N-formyl aspartame compounds |
ES2089276T5 (es) * | 1991-04-24 | 2001-01-16 | Mitsui Chemicals Inc | Metodo de preparacion del ester metilico de la alfa-l-aspartil-l-fenilalanina. |
US5616775A (en) * | 1994-05-05 | 1997-04-01 | Bristol-Myers Squibb Co. | Process for preparing homocystein analogs useful as intermediates for compounds containing a fused bicyclic ring |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3786039A (en) * | 1969-04-30 | 1974-01-15 | Ajinomoto Kk | Method of producing alpha-l-aspartyl-l-phenylalanine lower alkyl esters |
GB1309605A (en) * | 1970-01-31 | 1973-03-14 | Ajinomoto Kk | Process for producing alpha-dipeptide esters of l-aspartic acid |
JPS524972B2 (fr) * | 1972-05-22 | 1977-02-08 | ||
US3769333A (en) * | 1972-08-07 | 1973-10-30 | American Home Prod | L-aspartic acid derivatives |
-
0
- BE BE791544D patent/BE791544A/fr not_active IP Right Cessation
-
1971
- 1971-11-19 NL NLAANVRAGE7115944,A patent/NL172324C/xx not_active IP Right Cessation
-
1972
- 1972-11-08 GB GB5159172A patent/GB1359123A/en not_active Expired
- 1972-11-14 CA CA156,314A patent/CA1003408A/en not_active Expired
- 1972-11-15 US US306524A patent/US3879372A/en not_active Expired - Lifetime
- 1972-11-15 DE DE2256055A patent/DE2256055C2/de not_active Expired
- 1972-11-15 FR FR7240482A patent/FR2160471B1/fr not_active Expired
- 1972-11-16 IT IT54090/72A patent/IT982394B/it active
- 1972-11-16 CH CH1667772A patent/CH584188A5/xx not_active IP Right Cessation
- 1972-11-17 DK DK575372A patent/DK149126C/da not_active IP Right Cessation
- 1972-11-17 JP JP11546672A patent/JPS5417727B2/ja not_active Expired
- 1972-11-20 SE SE7215076A patent/SE393603B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
US3879372A (en) | 1975-04-22 |
IT982394B (it) | 1974-10-21 |
JPS4861451A (fr) | 1973-08-28 |
GB1359123A (en) | 1974-07-10 |
FR2160471A1 (fr) | 1973-06-29 |
NL172324C (nl) | 1983-08-16 |
NL172324B (nl) | 1983-03-16 |
JPS5417727B2 (fr) | 1979-07-02 |
FR2160471B1 (fr) | 1975-01-03 |
DE2256055A1 (de) | 1973-05-24 |
DE2256055C2 (de) | 1984-07-05 |
NL7115944A (fr) | 1973-05-22 |
DK149126B (da) | 1986-02-03 |
CA1003408A (en) | 1977-01-11 |
DK149126C (da) | 1986-06-23 |
CH584188A5 (fr) | 1977-01-31 |
SE393603B (sv) | 1977-05-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: STAMICARBON N.V. Effective date: 19911130 |