AU2001235358A1 - Method for the preparation of citalopram - Google Patents

Method for the preparation of citalopram

Info

Publication number
AU2001235358A1
AU2001235358A1 AU2001235358A AU3535801A AU2001235358A1 AU 2001235358 A1 AU2001235358 A1 AU 2001235358A1 AU 2001235358 A AU2001235358 A AU 2001235358A AU 3535801 A AU3535801 A AU 3535801A AU 2001235358 A1 AU2001235358 A1 AU 2001235358A1
Authority
AU
Australia
Prior art keywords
formula
compound
citalopram
followed
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2001235358A
Other languages
English (en)
Inventor
Haleh Ahmadian
Hans Petersen
Michael Harold Rock
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
H Lundbeck AS
Original Assignee
H Lundbeck AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H Lundbeck AS filed Critical H Lundbeck AS
Publication of AU2001235358A1 publication Critical patent/AU2001235358A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
AU2001235358A 2000-02-24 2001-02-22 Method for the preparation of citalopram Abandoned AU2001235358A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DKPA200000296 2000-02-24
DKPA200000296 2000-02-24
DKPA200000401 2000-03-13
DKPA200000401 2000-03-13
PCT/DK2001/000123 WO2001043525A2 (fr) 2000-02-24 2001-02-22 Procede pour la preparation de citalopram

Publications (1)

Publication Number Publication Date
AU2001235358A1 true AU2001235358A1 (en) 2001-06-25

Family

ID=26068779

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2001235358A Abandoned AU2001235358A1 (en) 2000-02-24 2001-02-22 Method for the preparation of citalopram

Country Status (26)

Country Link
US (1) US6420574B2 (fr)
EP (1) EP1259501A2 (fr)
JP (1) JP2003523955A (fr)
KR (1) KR20020081355A (fr)
CN (1) CN1608057A (fr)
AR (1) AR029658A1 (fr)
AU (1) AU2001235358A1 (fr)
BE (1) BE1011177A6 (fr)
BG (1) BG107061A (fr)
BR (1) BR0108937A (fr)
CA (1) CA2401236A1 (fr)
EA (1) EA005315B1 (fr)
FR (1) FR2805812A1 (fr)
GR (1) GR1004073B (fr)
HR (1) HRP20020660A2 (fr)
HU (1) HUP0300212A2 (fr)
IE (1) IES20010163A2 (fr)
IL (1) IL151059A0 (fr)
IS (1) IS6487A (fr)
IT (1) ITMI20010386A1 (fr)
MX (1) MXPA02008228A (fr)
NL (1) NL1017415C1 (fr)
NO (1) NO20023928D0 (fr)
PL (1) PL363119A1 (fr)
SK (1) SK13672002A3 (fr)
WO (1) WO2001043525A2 (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
CN1142926C (zh) * 1999-04-14 2004-03-24 H·隆德贝克有限公司 制备西酞普兰的方法
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
PT1298124E (pt) 1999-10-25 2007-05-31 Lundbeck & Co As H Método para a preparação de citalopram
US6310222B1 (en) * 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
PT1246812E (pt) 1999-12-28 2004-08-31 Lundbeck & Co As H Metodo para a preparacao de citalopram
EP1246813B1 (fr) 1999-12-30 2003-11-05 H. Lundbeck A/S Procede de preparation de citaloprame
ATE252570T1 (de) * 2000-01-14 2003-11-15 Lundbeck & Co As H Verfahren zur herstellung von 5-cyanophthalid
US6433196B1 (en) * 2000-02-17 2002-08-13 Sumika Fine Chemicals Co., Ltd. Production method of citalopram, intermediate therefor and production method of the intermediate
NL1017417C1 (nl) * 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NZ521201A (en) 2000-03-13 2004-02-27 H Method for the preparation of citalopram
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
EP1265881A1 (fr) * 2000-03-13 2002-12-18 H. Lundbeck A/S Alkylation progressive de 1-(4-fluorophenyl)-1,3-dihydroisobenzofuranes 5-substitues
IL151488A0 (en) 2000-03-14 2003-04-10 Lundbeck & Co As H Method for the preparation of citalopram
EA200200982A1 (ru) * 2000-03-16 2003-02-27 Х.Лундбекк А/С Способ получения 5-циано-1-(4-фторфенил)-1,3-дигидроизобензофуранов
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IL144816A (en) 2000-08-18 2005-09-25 Lundbeck & Co As H Method for the preparation of citalopram
CA2360303C (fr) 2000-12-22 2003-08-12 Marco Villa Procede de preparation de citalopram pur
AR034759A1 (es) * 2001-07-13 2004-03-17 Lundbeck & Co As H Metodo para la preparacion de escitalopram
KR20050043776A (ko) * 2001-11-08 2005-05-11 세프라코 아이엔시. 거울상 이성질체로 농축된, 시탈로프람의 데스메틸 및디데스메틸 대사물을 이용한 우울증 및 다른 중추신경계질환 치료방법
PE20040991A1 (es) 2002-08-12 2004-12-27 Lundbeck & Co As H Separacion de intermediarios para la preparacion de escitalopram
TR200504022T1 (tr) * 2003-03-24 2006-08-21 Hetero Drugs Limited (S)-sitalopram oksalatın yeni sıvı kristal formları.
WO2005047274A1 (fr) * 2003-11-12 2005-05-26 Dr. Reddy's Laboratories, Inc. Preparation d'escitaloprame
TWI339651B (en) 2004-02-12 2011-04-01 Lundbeck & Co As H Method for the separation of intermediates which may be used for the preparation of escitalopram
GB0601286D0 (en) 2006-01-23 2006-03-01 Sandoz Ag Asymmetric synthesis
CA2685424A1 (fr) * 2007-05-18 2008-11-27 Cipla Limited Procede de preparation d'escitalopram
WO2009111031A2 (fr) * 2008-03-04 2009-09-11 Intra-Cellular Therapies, Inc. Procédés de traitement de symptômes vasomoteurs

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (fr) 1965-03-18
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
US5296007A (en) 1986-11-17 1994-03-22 Ensci Inc. Process for removing sulfur from coal
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
DE1015416T1 (de) 1997-07-08 2000-10-05 Lundbeck A S Kobenhavn Valby H Verfahren zur herstellung von citalopram
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
JP3813820B2 (ja) 1997-11-11 2006-08-23 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
WO2000023431A1 (fr) 1998-10-20 2000-04-27 H. Lundbeck A/S Methode de preparation du citalopram
EA003057B1 (ru) 1998-12-23 2002-12-26 Х.Лундбекк А/С Способ получения 5-цианофталида
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
CN1142926C (zh) 1999-04-14 2004-03-24 H·隆德贝克有限公司 制备西酞普兰的方法
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
EP1228056B1 (fr) 1999-10-25 2004-09-22 H. Lundbeck A/S Procede de preparation de citaloprame
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate

Also Published As

Publication number Publication date
NL1017415C1 (nl) 2001-05-18
WO2001043525A3 (fr) 2002-01-31
NO20023928L (no) 2002-08-19
IS6487A (is) 2002-07-29
IES20010163A2 (en) 2002-03-06
EA005315B1 (ru) 2004-12-30
MXPA02008228A (es) 2004-04-05
NO20023928D0 (no) 2002-08-19
SK13672002A3 (sk) 2003-03-04
US6420574B2 (en) 2002-07-16
BE1011177A6 (fr) 2001-07-03
BG107061A (en) 2003-05-30
WO2001043525A2 (fr) 2001-06-21
FR2805812A1 (fr) 2001-09-07
JP2003523955A (ja) 2003-08-12
IL151059A0 (en) 2003-04-10
AR029658A1 (es) 2003-07-10
HUP0300212A2 (hu) 2003-06-28
GR1004073B (el) 2002-11-26
ITMI20010386A1 (it) 2002-08-26
CN1608057A (zh) 2005-04-20
GR20010100098A (el) 2001-10-31
BR0108937A (pt) 2003-06-17
EA200200898A1 (ru) 2003-02-27
CA2401236A1 (fr) 2001-06-21
KR20020081355A (ko) 2002-10-26
EP1259501A2 (fr) 2002-11-27
PL363119A1 (en) 2004-11-15
US20010027256A1 (en) 2001-10-04
HRP20020660A2 (en) 2004-12-31

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