ATE80380T1 - Diastereoselektives verfahren zur herstellung von zwischenprodukten verwendbar zur peptidderivatensynthese. - Google Patents
Diastereoselektives verfahren zur herstellung von zwischenprodukten verwendbar zur peptidderivatensynthese.Info
- Publication number
- ATE80380T1 ATE80380T1 AT89107141T AT89107141T ATE80380T1 AT E80380 T1 ATE80380 T1 AT E80380T1 AT 89107141 T AT89107141 T AT 89107141T AT 89107141 T AT89107141 T AT 89107141T AT E80380 T1 ATE80380 T1 AT E80380T1
- Authority
- AT
- Austria
- Prior art keywords
- preparation
- intermediate products
- peptide derivative
- derivative synthesis
- diastereoselective process
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/30—Preparation of optical isomers
- C07C227/32—Preparation of optical isomers by stereospecific synthesis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
- C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C317/50—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/63—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton the carbon skeleton being further substituted by nitrogen atoms, not being part of nitro or nitroso groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT20542/88A IT1217567B (it) | 1988-05-11 | 1988-05-11 | Processo diastereoselettivo per la preparazione di intermedi utili per la sintesi di derivati peptidici |
EP89107141A EP0341462B1 (de) | 1988-05-11 | 1989-04-20 | Diastereoselektives Verfahren zur Herstellung von Zwischenprodukten verwendbar zur Peptidderivatensynthese |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE80380T1 true ATE80380T1 (de) | 1992-09-15 |
Family
ID=11168517
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT89107141T ATE80380T1 (de) | 1988-05-11 | 1989-04-20 | Diastereoselektives verfahren zur herstellung von zwischenprodukten verwendbar zur peptidderivatensynthese. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5157143A (de) |
EP (1) | EP0341462B1 (de) |
JP (1) | JP2860559B2 (de) |
AT (1) | ATE80380T1 (de) |
DE (1) | DE68902771T2 (de) |
ES (1) | ES2052801T3 (de) |
GR (1) | GR3006432T3 (de) |
IT (1) | IT1217567B (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5648511A (en) * | 1990-11-19 | 1997-07-15 | G.D. Searle & Co. | Method for making intermediates useful in the synthesis of retroviral protease inhibitors |
US6743929B1 (en) * | 1992-08-25 | 2004-06-01 | G. D. Searle & Co. | Sulfonylalkanoylamino hydroxyethylamino sulfonamides useful as retroviral protease inhibitors |
EP0885879B1 (de) * | 1996-02-08 | 2004-12-15 | Nippon Kayaku Kabushiki Kaisha | Verfahren zur erzeugung optisch aktiver cyanohydrine |
JP2001048850A (ja) | 1999-05-28 | 2001-02-20 | Kanegafuchi Chem Ind Co Ltd | ノルスタチン誘導体の製造法 |
JP2002047256A (ja) * | 2000-07-26 | 2002-02-12 | Kanegafuchi Chem Ind Co Ltd | α−アミノ−α´,α´,α´−トリハロケトン誘導体、α−アミノ−α´,α´,α´−トリハロアルコ−ル誘導体、及び、α−ヒドロキシ−β−アミノカルボン酸誘導体の製造法 |
WO2007029587A1 (ja) | 2005-09-05 | 2007-03-15 | Dainippon Sumitomo Pharma Co., Ltd. | βセクレターゼ阻害剤 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5936902B2 (ja) * | 1977-06-22 | 1984-09-06 | 財団法人微生物化学研究会 | (2s,3r)−3−アミノ−2−ヒドロキシ−4−p−ヒドロキシフエニルブタノイル−(s)−ロイシンおよびその製造法 |
ES486572A1 (es) * | 1978-11-25 | 1980-09-16 | Nippon Kayaku Kk | Procedimiento para la fabricacion de acidos treo-3-amino-2- hidroxibutanoil amonoaceticos. |
JPS6033439B2 (ja) * | 1980-03-07 | 1985-08-02 | 財団法人相模中央化学研究所 | ジペプチドの製造方法 |
-
1988
- 1988-05-11 IT IT20542/88A patent/IT1217567B/it active
-
1989
- 1989-04-20 DE DE8989107141T patent/DE68902771T2/de not_active Expired - Fee Related
- 1989-04-20 AT AT89107141T patent/ATE80380T1/de active
- 1989-04-20 ES ES89107141T patent/ES2052801T3/es not_active Expired - Lifetime
- 1989-04-20 EP EP89107141A patent/EP0341462B1/de not_active Expired - Lifetime
- 1989-05-11 US US07/350,462 patent/US5157143A/en not_active Expired - Fee Related
- 1989-05-11 JP JP1118483A patent/JP2860559B2/ja not_active Expired - Lifetime
-
1992
- 1992-12-02 GR GR920402796T patent/GR3006432T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE68902771D1 (de) | 1992-10-15 |
EP0341462A1 (de) | 1989-11-15 |
GR3006432T3 (de) | 1993-06-21 |
JPH0228144A (ja) | 1990-01-30 |
ES2052801T3 (es) | 1994-07-16 |
IT8820542A0 (it) | 1988-05-11 |
DE68902771T2 (de) | 1993-01-07 |
US5157143A (en) | 1992-10-20 |
IT1217567B (it) | 1990-03-30 |
EP0341462B1 (de) | 1992-09-09 |
JP2860559B2 (ja) | 1999-02-24 |
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