ATE66215T1 - Cinnolinderivate. - Google Patents

Cinnolinderivate.

Info

Publication number: ATE66215T1
Authority: AT; Austria
Prior art keywords: cinnoline derivatives; cinnoline; derivatives
Prior art date: 1985-05-30

Application number

AT86303963T

Other languages

English (en)

Inventor

James Franklin Resch

Original Assignee

Ici America Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-05-30

Filing date

1986-05-23

Publication date

1991-08-15

1986-05-23 Application filed by Ici America Inc filed Critical Ici America Inc

1991-08-15 Application granted granted Critical

1991-08-15 Publication of ATE66215T1 publication Critical patent/ATE66215T1/de

Links

WCZVZNOTHYJIEI-UHFFFAOYSA-N cinnoline Chemical class N1=NC=CC2=CC=CC=C21 WCZVZNOTHYJIEI-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
- C07D237/28—Cinnolines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT86303963T 1985-05-30 1986-05-23 Cinnolinderivate. ATE66215T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB858513639A GB8513639D0 (en)	1985-05-30	1985-05-30	Cinnoline compounds
EP86303963A EP0205272B1 (de)	1985-05-30	1986-05-23	Cinnolinderivate

Publications (1)

Publication Number	Publication Date
ATE66215T1 true ATE66215T1 (de)	1991-08-15

Family

ID=10579908

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT86303963T ATE66215T1 (de)	1985-05-30	1986-05-23	Cinnolinderivate.

Country Status (25)

Country	Link
US (1)	US4886800A (de)
EP (1)	EP0205272B1 (de)
JP (1)	JPH0713062B2 (de)
KR (1)	KR900004402B1 (de)
CN (1)	CN1014060B (de)
AR (1)	AR242026A1 (de)
AT (1)	ATE66215T1 (de)
AU (1)	AU592086B2 (de)
CA (1)	CA1309406C (de)
DE (1)	DE3680828D1 (de)
DK (1)	DK162221C (de)
ES (3)	ES8801803A1 (de)
FI (1)	FI85584C (de)
GB (2)	GB8513639D0 (de)
GR (1)	GR861411B (de)
HU (1)	HU199433B (de)
IE (1)	IE58782B1 (de)
IL (1)	IL78992A0 (de)
MW (1)	MW4386A1 (de)
NO (1)	NO171592C (de)
PH (1)	PH23518A (de)
PL (1)	PL149227B1 (de)
PT (1)	PT82678B (de)
SU (1)	SU1500158A3 (de)
ZA (1)	ZA863664B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8702288D0 (en) *	1987-02-02	1987-03-11	Erba Farmitalia	Cinnoline-carboxamides
DE68902490T2 (de) *	1988-02-09	1992-12-24	Ici America Inc	Pharmazeutische zusammensetzung.
US4925844A (en) *	1988-02-09	1990-05-15	Ici Americas Inc.	Antagonizing the pharmacological effects of a benzodiazepine receptor agonist
JPH09510695A (ja) *	1994-01-03	1997-10-28	エイシア・ファーマシュウティカルズ，インコーポレイテッド	８−アザ、６−アザ、および６，８−ジアザ−１，４−ジヒドロキノキサリン−２，３−ジオン類およびそのグリシン／ｎｍｄａリセプターに対するアンタゴニストとしての使用
JP2003529601A (ja)	2000-03-21	2003-10-07	ファルマシア・アンド・アップジョン・カンパニー	抗ウイルス剤としての４−オキソ−１，４−ジヒドロ［１，８］ナフチリジン−３−カルボキサミド
EP1265873B1 (de)	2000-03-21	2003-10-15	PHARMACIA & UPJOHN COMPANY	4-oxo-1,4-dihydro-3-cinnolinecarbonsäure-amide als antivirusmittel
WO2001081318A1 (en)	2000-03-21	2001-11-01	Pharmacia & Upjohn Company	4-hydroxycinnoline-3-carboxyamides as antiviral agents
MXPA02009250A (es)	2000-03-21	2003-03-12	Upjohn Co	4-hidroxi-1,8-naftiridin--3-carboxamidas como agentes antivirales.
ES2391472T3 (es) *	2005-12-20	2012-11-27	Astrazeneca Ab	Derivados de cinnolina sustituidos como moduladores del receptor de GABAA y método para su síntesis
US7465795B2 (en)	2005-12-20	2008-12-16	Astrazeneca Ab	Compounds and uses thereof
TW200911760A (en) *	2007-06-19	2009-03-16	Astrazeneca Ab	Compounds and uses thereof
WO2010123443A1 (en) *	2009-04-21	2010-10-28	Astrazeneca Ab	Pharmaceutical composition comprising 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n- propylcinnoline-3-carboxamide hydrogen sulphate.
WO2010123441A1 (en) *	2009-04-21	2010-10-28	Astrazeneca Ab	Crystalline form of 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n-propylcinnoline-3- carboxamide hydrogen sulphate, for treatment of anxiety disorders
WO2010123440A1 (en) *	2009-04-21	2010-10-28	Astrazeneca Ab	Pharmaceutical composition comprising 4-amino-8-(2-fluoro-6-methoxy-phenyl)-n- propylcinnoline-3-carboxamide hydrogen sulphate and rate-controlling polymer
KR20140041583A (ko) *	2011-05-23	2014-04-04	엘란 파마슈티컬스, 엘엘씨	Ｌｒｒｋ2 키나제 활성의 억제제
CN111905828B (zh) *	2020-08-24	2022-04-19	万华化学集团股份有限公司	一种萘基配体mof活性炭复合催化剂及其制备方法和用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3657241A (en) *	1970-03-12	1972-04-18	Dow Chemical Co	Substituted cinnoline compounds
GB1306839A (en) *	1970-10-16	1973-02-14	Ici Ltd	Pharmaceutical compositions
GB1474399A (en) *	1974-08-19	1977-05-25	Ici Ltd	Cinnolin-3-yl carboxylic acids and derivatives thereof
US4085103A (en) *	1974-11-07	1978-04-18	Imperial Chemical Industries Limited	6-Substituted-4-hydroxycinnolin-3-yl-carboxylic acids and esters thereof
GB1472766A (en) *	1974-11-07	1977-05-04	Ici Ltd	Hydroxycinnoline derivatives processes for their preparation and their use in pharmaceutical compositions
DD123525A1 (de) *	1976-02-10	1977-01-05
US4379929A (en) *	1981-03-19	1983-04-12	Eli Lilly And Company	4(1H)-Oxocinnoline-3-carboxylic acid derivatives
US4729782A (en) *	1983-09-14	1988-03-08	Lafarge Coppee	Pollen suppressant comprising a fused pyridazinone
GB8702288D0 (en) *	1987-02-02	1987-03-11	Erba Farmitalia	Cinnoline-carboxamides

1985
- 1985-05-30 GB GB858513639A patent/GB8513639D0/en active Pending
1986
- 1986-05-09 GB GB868611419A patent/GB8611419D0/en active Pending
- 1986-05-13 IE IE126786A patent/IE58782B1/en not_active IP Right Cessation
- 1986-05-16 ZA ZA863664A patent/ZA863664B/xx unknown
- 1986-05-20 PH PH33792A patent/PH23518A/en unknown
- 1986-05-22 AU AU57819/86A patent/AU592086B2/en not_active Ceased
- 1986-05-23 DE DE8686303963T patent/DE3680828D1/de not_active Expired - Lifetime
- 1986-05-23 EP EP86303963A patent/EP0205272B1/de not_active Expired - Lifetime
- 1986-05-23 AT AT86303963T patent/ATE66215T1/de not_active IP Right Cessation
- 1986-05-28 HU HU862243A patent/HU199433B/hu not_active IP Right Cessation
- 1986-05-29 US US06/868,791 patent/US4886800A/en not_active Expired - Lifetime
- 1986-05-29 SU SU864027693A patent/SU1500158A3/ru active
- 1986-05-29 CA CA000510335A patent/CA1309406C/en not_active Expired - Lifetime
- 1986-05-29 NO NO862141A patent/NO171592C/no unknown
- 1986-05-30 DK DK256386A patent/DK162221C/da not_active IP Right Cessation
- 1986-05-30 PL PL1986259791A patent/PL149227B1/pl unknown
- 1986-05-30 PT PT82678A patent/PT82678B/pt unknown
- 1986-05-30 MW MW43/86A patent/MW4386A1/xx unknown
- 1986-05-30 KR KR1019860004274A patent/KR900004402B1/ko not_active IP Right Cessation
- 1986-05-30 AR AR86304166A patent/AR242026A1/es active
- 1986-05-30 JP JP61123840A patent/JPH0713062B2/ja not_active Expired - Lifetime
- 1986-05-30 CN CN86104358A patent/CN1014060B/zh not_active Expired
- 1986-05-30 ES ES555546A patent/ES8801803A1/es not_active Expired
- 1986-05-30 GR GR861411A patent/GR861411B/el unknown
- 1986-05-30 FI FI862315A patent/FI85584C/fi not_active IP Right Cessation
- 1986-06-02 IL IL78992A patent/IL78992A0/xx not_active IP Right Cessation
1987
- 1987-04-30 ES ES557522A patent/ES8801903A1/es not_active Expired
- 1987-12-16 ES ES557790A patent/ES8802611A1/es not_active Expired

Also Published As

Publication number	Publication date
NO171592C (no)	1993-04-07
ZA863664B (en)	1987-03-25
DK256386A (da)	1986-12-01
SU1500158A3 (ru)	1989-08-07
AU5781986A (en)	1986-12-04
GB8513639D0 (en)	1985-07-03
IL78992A0 (en)	1986-09-30
KR860008986A (ko)	1986-12-19
JPH0713062B2 (ja)	1995-02-15
ES557522A0 (es)	1988-03-01
KR900004402B1 (ko)	1990-06-25
ES8801903A1 (es)	1988-03-01
CA1309406C (en)	1992-10-27
GR861411B (en)	1986-08-28
PH23518A (en)	1989-08-16
EP0205272A3 (en)	1987-11-19
US4886800A (en)	1989-12-12
ES8802611A1 (es)	1988-10-01
FI85584B (fi)	1992-01-31
AR242026A1 (es)	1993-02-26
FI862315A0 (fi)	1986-05-30
MW4386A1 (en)	1987-06-19
DE3680828D1 (de)	1991-09-19
HUT41012A (en)	1987-03-30
PL149227B1 (en)	1990-01-31
ES8801803A1 (es)	1988-02-16
HU199433B (en)	1990-02-28
FI85584C (fi)	1992-05-11
PT82678B (pt)	1988-03-03
DK162221C (da)	1992-03-02
NO171592B (no)	1992-12-28
NO862141L (no)	1986-12-01
GB8611419D0 (en)	1986-06-18
AU592086B2 (en)	1990-01-04
EP0205272B1 (de)	1991-08-14
CN86104358A (zh)	1987-04-01
CN1014060B (zh)	1991-09-25
EP0205272A2 (de)	1986-12-17
PT82678A (en)	1986-06-01
IE861267L (en)	1986-11-30
IE58782B1 (en)	1993-11-17
FI862315A (fi)	1986-12-01
ES557790A0 (es)	1988-10-01
JPS61280483A (ja)	1986-12-11
DK256386D0 (da)	1986-05-30
ES555546A0 (es)	1988-02-16
DK162221B (da)	1991-09-30

Legal Events

Date	Code	Title	Description
1992-06-15	UEP	Publication of translation of european patent specification
2006-08-15	EELA	Cancelled due to lapse of time

Publication	Publication Date	Title
DE3681208D1 (de)	1991-10-10	Fluormeter.
DE3685608D1 (de)	1992-07-16	8-phenylxanthine.
DE3685611D1 (de)	1992-07-16	Polysiloxanelastomer.
FI870381A (fi)	1987-01-29	Tillslutningsorgan foer roerledning.
FI863215A (fi)	1987-02-07	Graeddartade rengoeringskompositioner.
ATE55980T1 (de)	1990-09-15	2-hydroxy-3-phenoxypropylamine.
NO864976D0 (no)	1986-12-10	Slisseringsmaskin.
DE3687867D1 (de)	1993-04-08	Mikrorechner.
ATE50243T1 (de)	1990-02-15	Fluorbenzylester.
FI860422A0 (fi)	1986-01-29	Flamdetektor.
DE3680828D1 (de)	1991-09-19	Cinnolinderivate.
NO864894L (no)	1987-06-09	Doerlaas.
DE3688642D1 (de)	1993-08-05	Fdm-tdm-transmultiplexer.
DE3680606D1 (de)	1991-09-05	Loetapparat.
DE3683724D1 (de)	1992-03-12	Zahnstutz.
DE3686729D1 (de)	1992-10-22	Aminoalkylpyridinamide.
DE3670979D1 (de)	1990-06-13	Raederfalzapparat.
FI73923B (fi)	1987-08-31	Polyamidhaltig maongskiktsfilm.
DE3673520D1 (de)	1990-09-20	Perfluorpolyaether.
FI863293A (fi)	1987-03-04	Ornamentprodukt.
DE3681550D1 (de)	1991-10-24	3-perfluoralkyl-5-hydroxy-isoxazole.
DE3670589D1 (de)	1990-05-31	Sandstrahlgeraet.
DE3670767D1 (de)	1990-06-07	Rioprostil-pvp-komplex.
DE3673746D1 (de)	1990-10-04	Pudermine.
FI863624A (fi)	1986-09-09	Byggbar leksak.