ATE520986T1 - Proteasenachweis - Google Patents

Proteasenachweis

Info

Publication number
ATE520986T1
ATE520986T1 AT07705268T AT07705268T ATE520986T1 AT E520986 T1 ATE520986 T1 AT E520986T1 AT 07705268 T AT07705268 T AT 07705268T AT 07705268 T AT07705268 T AT 07705268T AT E520986 T1 ATE520986 T1 AT E520986T1
Authority
AT
Austria
Prior art keywords
analyte
proteases
detection
protease
sample
Prior art date
Application number
AT07705268T
Other languages
English (en)
Inventor
Paul James Davis
Mark James Davis
Mark Burnapp
Original Assignee
Mologic Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mologic Ltd filed Critical Mologic Ltd
Application granted granted Critical
Publication of ATE520986T1 publication Critical patent/ATE520986T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575Hormones
    • G01N2333/59Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pathology (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT07705268T 2006-02-23 2007-02-23 Proteasenachweis ATE520986T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0603665A GB2435511A (en) 2006-02-23 2006-02-23 Protease detection
PCT/GB2007/000637 WO2007096637A1 (en) 2006-02-23 2007-02-23 Protease detection

Publications (1)

Publication Number Publication Date
ATE520986T1 true ATE520986T1 (de) 2011-09-15

Family

ID=36178649

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07705268T ATE520986T1 (de) 2006-02-23 2007-02-23 Proteasenachweis

Country Status (6)

Country Link
US (1) US7935497B2 (de)
EP (1) EP1989549B1 (de)
AT (1) ATE520986T1 (de)
AU (1) AU2007217114B2 (de)
GB (1) GB2435511A (de)
WO (1) WO2007096637A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7906276B2 (en) 2004-06-30 2011-03-15 Kimberly-Clark Worldwide, Inc. Enzymatic detection techniques
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
US7504235B2 (en) 2005-08-31 2009-03-17 Kimberly-Clark Worldwide, Inc. Enzyme detection technique
GB2435511A (en) 2006-02-23 2007-08-29 Mologic Ltd Protease detection
GB2435510A (en) 2006-02-23 2007-08-29 Mologic Ltd Enzyme detection product and methods
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
US8758989B2 (en) 2006-04-06 2014-06-24 Kimberly-Clark Worldwide, Inc. Enzymatic detection techniques
GB2437311A (en) * 2006-04-07 2007-10-24 Mologic Ltd A protease detection product
US7897360B2 (en) 2006-12-15 2011-03-01 Kimberly-Clark Worldwide, Inc. Enzyme detection techniques
GB2452076A (en) 2007-08-23 2009-02-25 Mologic Ltd Detection of enzymes by detecting binding of substrate recognition molecules to modified substrates
GB2454672A (en) * 2007-11-13 2009-05-20 Mologic Ltd Chromogenic protease substrates
GB0904080D0 (en) 2009-03-09 2009-04-22 Mologic Ltd Imaging method
EP2475778B1 (de) 2009-09-09 2014-10-22 3M Innovative Properties Company Verfahren und Kit für Protease-Enzym-Assays
GB201318728D0 (en) 2013-10-23 2013-12-04 Mologic Ltd Detection of cleavage activity of an enzyme
SE538541C2 (en) * 2015-01-19 2016-09-13 Fogelstrand Per Method for preparing a biological sample for use in an immunolabeling process
GB201605110D0 (en) 2016-03-24 2016-05-11 Mologic Ltd Detecting sepsis
KR102105157B1 (ko) * 2018-08-31 2020-04-27 경희대학교 산학협력단 펩신에 의해 특이적으로 분해되는 펩타이드 및 이를 포함하는 역류성 인후두염 진단용 키트
GB201902458D0 (en) 2019-02-22 2019-04-10 Mologic Ltd Treatment stratification for an excerbation of inflamation
KR102383155B1 (ko) * 2020-02-19 2022-04-06 주식회사 큐베스트바이오 반응 온도 및 반응 시간 조절이 가능한 스트립 및 그 스트립을 이용한 샘플 분석 시스템
WO2024144315A1 (ko) * 2022-12-29 2024-07-04 아주대학교산학협력단 표적 프로테아제 검출용 프로테아제 센서 및 이를 이용한 프로테아제 검출용 키트

Family Cites Families (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1006557B (it) 1971-09-08 1976-10-20 Bagshawe Kenneth Dawson Cella di reazione particolarmente utile in prove di radioimmunita
US4055394A (en) 1976-10-18 1977-10-25 Akzona Incorporated Diagnostic test card
CA1095819A (en) 1977-01-14 1981-02-17 Eastman Kodak Company Element for analysis of liquids
US4178153A (en) 1977-11-21 1979-12-11 Damon Corporation Method and apparatus for chemical spot test analysis
US4258001A (en) 1978-12-27 1981-03-24 Eastman Kodak Company Element, structure and method for the analysis or transport of liquids
JPS568549A (en) 1979-07-02 1981-01-28 Fuji Photo Film Co Ltd Multilayer chemical analyzing material
JPS5764160A (en) 1980-10-06 1982-04-19 Yokogawa Hokushin Electric Corp Method and apparatus for measuring urea
JPS5767860A (en) 1980-10-15 1982-04-24 Fuji Photo Film Co Ltd Material for multilayer analysis
DE3247608A1 (de) 1982-12-23 1984-07-05 Boehringer Mannheim Gmbh, 6800 Mannheim Teststreifen
US4851356A (en) 1983-05-06 1989-07-25 The Trustees Of Columbia University In The City Of New York Immunoassay for human chorionic gonadotropin
US4522923A (en) 1983-10-03 1985-06-11 Genetic Diagnostics Corporation Self-contained assay method and kit
US4703017C1 (en) 1984-02-14 2001-12-04 Becton Dickinson Co Solid phase assay with visual readout
JPS60224063A (ja) 1984-04-20 1985-11-08 Terumo Corp 試験用具
US4632901A (en) 1984-05-11 1986-12-30 Hybritech Incorporated Method and apparatus for immunoassays
US5879881A (en) 1985-04-04 1999-03-09 Hybritech, Incorporated Solid phase system for use in ligand-receptor assays
US5223403A (en) 1985-05-31 1993-06-29 University Of Michigan Device for diagnosing periodontal disease
US4689240A (en) 1985-06-20 1987-08-25 Miles Laboratories, Inc. Method for forming volume independent test device
US4647430A (en) 1985-06-20 1987-03-03 Miles Laboratories, Inc. Volume independent test device
US5236826A (en) 1985-12-10 1993-08-17 Murex Corporation Immunoassay for the detection or quantitation of an analyte
EP0291194B8 (de) * 1987-04-27 2003-10-22 Inverness Medical Switzerland GmbH Immunoassays und Vorrichtungen dafür
JPS63305251A (ja) 1987-06-05 1988-12-13 Dai Ichi Pure Chem Co Ltd ラテツクス凝集反応を利用する免疫学的測定方法
FR2621393B1 (fr) 1987-10-05 1991-12-13 Toledano Jacques Dispositif de detection immunoenzymatique de substances a partir d'une goutte de sang ou de liquide provenant d'un quelconque milieu biologique
FR2630827B1 (fr) 1988-04-28 1994-06-03 Oris Ind Dispositif et procede pour la determination qualitative et quantitative rapide de la presence d'un ligand reactif dans un fluide
DE3814370A1 (de) 1988-04-28 1989-11-09 Boehringer Mannheim Gmbh Testtraeger fuer die analyse einer probenfluessigkeit, verfahren zur durchfuehrung einer solchen analyse und herstellungsverfahren
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
US5064770A (en) 1989-08-01 1991-11-12 Wisconsin Alumni Research Foundation Assay for 1,25-dihydroxy vitamin d receptor protein
US5185249A (en) 1990-04-04 1993-02-09 Eastman Kodak Company Dry analytical element for assaying salicylate
US5171662A (en) * 1990-09-13 1992-12-15 The Upjohn Company Method of detecting HIV protease activity
ATE153138T1 (de) 1990-09-26 1997-05-15 Akers Lab Inc Verbessertes bestimmungsverfahren für liganden
AU9039691A (en) 1990-11-14 1992-06-11 Southern Research Institute Rapid diagnostic device and kit
EP0566695B1 (de) 1991-01-11 1999-06-02 Quidel Corporation Einstufiges querfluss analysenverfahren und ein darin verwendeter nichtsaugfähiger träger
ATE137334T1 (de) 1991-02-28 1996-05-15 Boehringer Mannheim Gmbh Testträger zur bestimmung eines analyten aus vollblut
US5869345A (en) 1991-05-29 1999-02-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing conductive barrier
GB9119102D0 (en) 1991-09-07 1991-10-23 Biosyn Ltd Bioimmunassay
DE4132743A1 (de) 1991-10-02 1993-04-08 Boehringer Mannheim Gmbh Testtraeger fuer die analyse von fluessigkeiten
US5296192A (en) 1992-04-03 1994-03-22 Home Diagnostics, Inc. Diagnostic test strip
US5447846A (en) 1992-07-17 1995-09-05 Fuji Photo Film C., Ltd. Homogeneous Immunoassay process using covalent conjugate of enzyme and plural monoclonal antibodies for different epitopes on analyte
US5601986A (en) * 1994-07-14 1997-02-11 Amgen Inc. Assays and devices for the detection of extrahepatic biliary atresia
US6686170B1 (en) 1994-08-17 2004-02-03 Abbott Laboratories Assay devices with mobile control reagents
AUPM769394A0 (en) 1994-08-25 1994-09-15 Commonwealth Scientific And Industrial Research Organisation Assay for the detection of proteases
US5607565A (en) 1995-03-27 1997-03-04 Coulter Corporation Apparatus for measuring analytes in a fluid sample
US5755231A (en) 1995-05-17 1998-05-26 Plus Bio, Inc. Test strip including integral specimen flow retarding structure
US5741659A (en) 1996-01-04 1998-04-21 The United States Of America As Represented By The Secretary Of The Navy Rapid microbial protease assay
US6096563A (en) 1996-03-29 2000-08-01 Strategic Diagnostics Inc. Dual particle immunoassay method and kit
WO1998000703A1 (en) 1996-07-03 1998-01-08 Plus Bio, Inc. Test strip including integral specimen flow retarding structure
US5879951A (en) 1997-01-29 1999-03-09 Smithkline Diagnostics, Inc. Opposable-element assay device employing unidirectional flow
US7312302B2 (en) 1997-02-20 2007-12-25 Oncolmmunin, Inc. Compositions for the detection of enzyme activity in biological samples and methods of use thereof
US5939252A (en) 1997-05-09 1999-08-17 Lennon; Donald J. Detachable-element assay device
US6040195A (en) 1997-06-10 2000-03-21 Home Diagnostics, Inc. Diagnostic sanitary test strip
WO1999067647A1 (en) 1998-06-24 1999-12-29 Chen & Chen, Llc Multi-layer testing column
US6140136A (en) 1998-09-18 2000-10-31 Syntron Bioresearch, Inc. Analytical test device and method of use
US20050003394A1 (en) * 1999-01-06 2005-01-06 Chondrogene Limited Method for the detection of rheumatoid arthritis related gene transcripts in blood
DE19916430C1 (de) 1999-04-12 2001-01-18 Inst Chemo Biosensorik Vorrichtung zur Verwendung bei der Durchführung von Rezeptor-Ligand- und Affinitätstests
AU4344800A (en) * 1999-04-16 2000-11-02 New York Blood Center, Inc., The Monoclonal antibodies reactive with fibrin(ogen) degradation products generated by matrix metalloproteinases
GB2350677A (en) * 1999-06-04 2000-12-06 Cambridge Life Sciences Enzyme detection
JP2001000197A (ja) * 1999-06-22 2001-01-09 Fuji Photo Film Co Ltd プロテアーゼ活性の測定方法
GB9923384D0 (en) 1999-10-05 1999-12-08 Univ Birmingham Fluid-flow control device
GB9925461D0 (en) 1999-10-27 1999-12-29 Genosis Ltd Assay device
US6316205B1 (en) 2000-01-28 2001-11-13 Genelabs Diagnostics Pte Ltd. Assay devices and methods of analyte detection
US6750034B1 (en) * 2000-06-30 2004-06-15 Ortho-Mcneil Pharmaceutical, Inc. DNA encoding human serine protease D-G
EP1410001A4 (de) 2000-10-25 2006-05-31 Michael M Miller Mehrschichtiges analyseelement und verfahren zur bestimmung von analyten in flüssigkeiten mit störenden substanzen
AU2002243236B2 (en) 2000-11-20 2007-11-08 20/20 Genesystems, Inc. Methods, devices, arrays and kits for detecting and analyzing biomolecules
KR100425525B1 (ko) 2000-11-21 2004-03-30 재단법인서울대학교산학협력재단 조산과 태아감염 및 태아손상을 산전 진단하기 위한진단시약 및 진단키트
FR2817961B1 (fr) 2000-12-08 2003-08-01 Diagast Barriere de separation temporaire, recipient la comprenant et procede de mise en oeuvre d'un test dans ce recipient
WO2002078875A1 (en) * 2001-03-29 2002-10-10 Showa Denko K.K. Closed forging metod, forging production system using the method, forging die used in the method and system, and preform or yoke produced by the method and system
US7531362B2 (en) 2001-06-07 2009-05-12 Medmira Inc. Rapid diagnostic assay
CA2456590A1 (en) * 2001-08-07 2003-02-20 Merck & Co., Inc. Biological assay detection method
WO2003023360A2 (en) * 2001-09-10 2003-03-20 Meso Scale Technologies, Llc Methods and apparatus for conducting multiple measurements on a sample
AU2002364609B2 (en) 2001-12-28 2008-04-03 Polymer Technology Systems, Inc. Test strip for determining concentration of multiple analytes in a single fluid sample
EP1472238B1 (de) 2002-02-01 2012-07-04 Promega Corporation Biolumineszenz protease assay
US7041453B2 (en) 2002-08-22 2006-05-09 Bioarray Solutions Ltd. Molecular constructs and methods of use for detection of biochemical reactions
CA2506197A1 (en) 2002-11-22 2004-06-10 Marligen Biosciences, Inc. Detection of protease enzymes
US7716030B2 (en) * 2003-02-28 2010-05-11 Vertex Pharmaceuticals Incorporated Target ligand generation
GB0311902D0 (en) 2003-05-22 2003-06-25 Cambridge Life Sciences Assay method and apparatus
GB0316075D0 (en) 2003-07-09 2003-08-13 Molecular Sensing Plc Protease detection assay
GB0317680D0 (en) 2003-07-29 2003-09-03 Univ Edinburgh Protease assay
GB2410086A (en) 2004-01-14 2005-07-20 British Biocell Internat Ltd Assay devices having flow block(s) to determine flow of liquids
US20080318342A1 (en) 2004-06-04 2008-12-25 Durack Matthew C A Diagnostic Testing Process and Apparatus Incorporating Controlled Sample Flow
US7906276B2 (en) 2004-06-30 2011-03-15 Kimberly-Clark Worldwide, Inc. Enzymatic detection techniques
GB2435511A (en) 2006-02-23 2007-08-29 Mologic Ltd Protease detection
GB2435512A (en) 2006-02-23 2007-08-29 Mologic Ltd A binding assay and assay device
GB2435510A (en) 2006-02-23 2007-08-29 Mologic Ltd Enzyme detection product and methods
GB2437311A (en) 2006-04-07 2007-10-24 Mologic Ltd A protease detection product

Also Published As

Publication number Publication date
US20090053738A1 (en) 2009-02-26
EP1989549A1 (de) 2008-11-12
US7935497B2 (en) 2011-05-03
WO2007096637A1 (en) 2007-08-30
AU2007217114A1 (en) 2007-08-30
AU2007217114B2 (en) 2012-04-05
GB2435511A (en) 2007-08-29
EP1989549B1 (de) 2011-08-17
GB0603665D0 (en) 2006-04-05

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