ATE504582T1 - Substituierte benzopyrane als selektive östrogenrezeptor-beta-agonisten - Google Patents

Substituierte benzopyrane als selektive östrogenrezeptor-beta-agonisten

Info

Publication number
ATE504582T1
ATE504582T1 AT05807448T AT05807448T ATE504582T1 AT E504582 T1 ATE504582 T1 AT E504582T1 AT 05807448 T AT05807448 T AT 05807448T AT 05807448 T AT05807448 T AT 05807448T AT E504582 T1 ATE504582 T1 AT E504582T1
Authority
AT
Austria
Prior art keywords
sub
sup
alkyl
estrogen receptor
selective estrogen
Prior art date
Application number
AT05807448T
Other languages
English (en)
Inventor
Bryan Norman
Timothy Richardson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of ATE504582T1 publication Critical patent/ATE504582T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/94—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
AT05807448T 2004-10-18 2005-10-05 Substituierte benzopyrane als selektive östrogenrezeptor-beta-agonisten ATE504582T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61962704P 2004-10-18 2004-10-18
PCT/US2005/035472 WO2006044176A1 (en) 2004-10-18 2005-10-05 Substituted benzopyrans as selective estrogen receptor-beta agonists

Publications (1)

Publication Number Publication Date
ATE504582T1 true ATE504582T1 (de) 2011-04-15

Family

ID=36010977

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05807448T ATE504582T1 (de) 2004-10-18 2005-10-05 Substituierte benzopyrane als selektive östrogenrezeptor-beta-agonisten

Country Status (8)

Country Link
US (1) US7354951B2 (de)
EP (1) EP1805160B1 (de)
JP (1) JP2008516949A (de)
AT (1) ATE504582T1 (de)
CA (1) CA2578300A1 (de)
DE (1) DE602005027378D1 (de)
ES (1) ES2361031T3 (de)
WO (1) WO2006044176A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2518819A1 (en) 2003-04-21 2004-11-04 Eli Lilly And Company Substituted benzopyrans as selective estrogen receptor-beta agonists
EP1853578A1 (de) 2005-02-15 2007-11-14 Eli Lilly And Company Substituierte tetraline als selektive östrogenrezeptor-beta-agonisten
US9623021B2 (en) 2007-01-22 2017-04-18 Gtx, Inc. Nuclear receptor binding agents
CN101641013B (zh) 2007-01-22 2014-07-30 Gtx公司 核受体结合剂
US9604931B2 (en) 2007-01-22 2017-03-28 Gtx, Inc. Nuclear receptor binding agents
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
EP3827820A1 (de) 2013-03-15 2021-06-02 The Johns Hopkins University Brivaracetam zur verbesserung der kognitiven funktion
AU2014228512A1 (en) 2013-03-15 2015-10-01 Agenebio, Inc. Methods and compositions for improving cognitive function
JP2016539954A (ja) 2013-12-05 2016-12-22 カロ ファーマ エービーＫａｒｏ Ｐｈａｒｍａ Ａｂ 中皮腫の処置で使用するためのエストロゲン受容体ベータアゴニスト
CN112843005B (zh) 2015-05-22 2023-02-21 艾吉因生物股份有限公司 左乙拉西坦的延时释放药物组合物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE529419T1 (de) 2000-03-01 2011-11-15 Organon Nv Chromanderivate als estrogene verbindungen
ES2286322T3 (es) * 2001-11-19 2007-12-01 Eli Lilly And Company Benzopirianos como agosnistas selectivos de receptores de estrogenos beta.
US6630508B1 (en) 2002-02-11 2003-10-07 Eli Lilly And Company Substituted benzopyrans as selective estrogen receptor β agonists
CA2518819A1 (en) 2003-04-21 2004-11-04 Eli Lilly And Company Substituted benzopyrans as selective estrogen receptor-beta agonists
WO2004094401A1 (en) 2003-04-21 2004-11-04 Eli Lilly And Company Substituted benzopyrans as selective estrogen receptor-beta agonists

Also Published As

Publication number Publication date
DE602005027378D1 (de) 2011-05-19
EP1805160A1 (de) 2007-07-11
JP2008516949A (ja) 2008-05-22
WO2006044176A1 (en) 2006-04-27
EP1805160B1 (de) 2011-04-06
ES2361031T3 (es) 2011-06-13
US20080064742A1 (en) 2008-03-13
US7354951B2 (en) 2008-04-08
CA2578300A1 (en) 2006-04-27

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