ATE483978T1 - Anti-epha2 antikörper als krebsdiagnostikum - Google Patents

Anti-epha2 antikörper als krebsdiagnostikum

Info

Publication number
ATE483978T1
ATE483978T1 AT00955686T AT00955686T ATE483978T1 AT E483978 T1 ATE483978 T1 AT E483978T1 AT 00955686 T AT00955686 T AT 00955686T AT 00955686 T AT00955686 T AT 00955686T AT E483978 T1 ATE483978 T1 AT E483978T1
Authority
AT
Austria
Prior art keywords
epha2
cancer diagnostic
epha2 antibodies
kits
overexpressed
Prior art date
Application number
AT00955686T
Other languages
English (en)
Inventor
Michael Kinch
Nicole Zantek
Katherine Kilpatrick
Original Assignee
Purdue Research Foundation
Glaxo Group Ltd
Univ North Carolina
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation, Glaxo Group Ltd, Univ North Carolina filed Critical Purdue Research Foundation
Application granted granted Critical
Publication of ATE483978T1 publication Critical patent/ATE483978T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
AT00955686T 1999-08-17 2000-08-17 Anti-epha2 antikörper als krebsdiagnostikum ATE483978T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14925999P 1999-08-17 1999-08-17
PCT/US2000/022669 WO2001012840A2 (en) 1999-08-17 2000-08-17 Anti-epha2 antibodies as a cancer diagnostic

Publications (1)

Publication Number Publication Date
ATE483978T1 true ATE483978T1 (de) 2010-10-15

Family

ID=22529464

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00955686T ATE483978T1 (de) 1999-08-17 2000-08-17 Anti-epha2 antikörper als krebsdiagnostikum

Country Status (8)

Country Link
EP (2) EP1210603B1 (de)
JP (3) JP4948728B2 (de)
AT (1) ATE483978T1 (de)
AU (1) AU785445C (de)
CA (1) CA2382655A1 (de)
DE (1) DE60045075D1 (de)
ES (1) ES2357296T3 (de)
WO (1) WO2001012840A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7192698B1 (en) 1999-08-17 2007-03-20 Purdue Research Foundation EphA2 as a diagnostic target for metastatic cancer
US6927203B1 (en) 1999-08-17 2005-08-09 Purdue Research Foundation Treatment of metastatic disease
WO2001074382A1 (en) 2000-03-31 2001-10-11 Purdue Research Foundation Method of treatment using ligand-immunogen conjugates
US7101976B1 (en) 2000-09-12 2006-09-05 Purdue Research Foundation EphA2 monoclonal antibodies and methods of making and using same
AU2002314433A1 (en) * 2001-07-02 2003-01-21 Licentia Ltd. Ephrin-tie receptor materials and methods
ES2338305T3 (es) * 2001-09-28 2010-05-06 Purdue Research Foundation Metodo de tratamiento que utiliza conjugados ligando-inmunogeno.
WO2003040304A2 (en) * 2001-11-09 2003-05-15 Neuronova Ab Method of proliferation in neurogenic regions
US20050069549A1 (en) 2002-01-14 2005-03-31 William Herman Targeted ligands
WO2004014292A2 (en) * 2002-05-10 2004-02-19 Purdue Research Foundation EphA2 AGONISTIC MONOCLONAL ANTIBODIES AND METHODS OF USE THEREOF
JP4557714B2 (ja) * 2002-05-10 2010-10-06 メディミューン，エルエルシー ＥｐｈＡ２モノクローナル抗体およびその使用法
JP2006501153A (ja) 2002-05-23 2006-01-12 パーデュー・リサーチ・ファウンデーション 診断及び治療用標的としての低分子量タンパク質チロシンホスファターゼ（ｌｍｗ−ｐｔｐ）
EP1628992A4 (de) * 2003-05-13 2008-04-16 Novartis Vaccines & Diagnostic Verfahren zur modulation der metastasierung sowie von metastasen herrührender verwandter ereignisse im skelett
AU2004281834A1 (en) * 2003-10-15 2005-04-28 Cerus Corporation Listeria-based EphA2 vaccines
AU2005277567A1 (en) 2004-08-16 2006-03-02 Medimmune, Llc Integrin antagonists with enhanced antibody dependent cell-mediated cytotoxicity activity
AU2006210460B2 (en) 2005-02-04 2012-04-05 Macrogenics West, Inc. Antibodies that bind to EphA2 and methods of use thereof
WO2007092299A2 (en) 2006-02-03 2007-08-16 Purdue Research Foundation Targeted conjugates and radiation
PL2199390T3 (pl) 2007-08-30 2017-06-30 Daiichi Sankyo Company, Limited Przeciwciało anty-epha2
JP6069806B2 (ja) * 2013-02-13 2017-02-01 国立大学法人 東京大学 がんの検査方法及び検査用キット
JP5875054B2 (ja) * 2013-02-13 2016-03-02 国立大学法人 東京大学 がんの検査方法及び検査用キット
JP6399013B2 (ja) * 2016-02-18 2018-10-03 トヨタ自動車株式会社 化学蓄熱器の制御装置
JP6729917B2 (ja) * 2016-08-19 2020-07-29 国立大学法人 東京大学 ＥｐｈＡ２ Ｎ末端フラグメント抗体

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0656367A1 (de) 1991-08-22 1995-06-07 Becton, Dickinson and Company Methoden und Zusammensetzungen zur Krebstherapie und zur Vorhersagbarkeit der Reaktionen auf diese Behandlung
US5457048A (en) * 1993-12-03 1995-10-10 La Jolla Cancer Research Foundation Eph-related tyrosine kinases, nucleotide sequences and methods of use
US5876949A (en) 1995-05-31 1999-03-02 The Trustees Of The University Of Pennsylvania Antibodies specific for fragile X related proteins and method of using the same

Also Published As

Publication number Publication date
EP1210603B1 (de) 2010-10-06
AU785445B2 (en) 2007-06-14
AU6784300A (en) 2001-03-13
WO2001012840A3 (en) 2001-05-03
DE60045075D1 (de) 2010-11-18
JP2012103264A (ja) 2012-05-31
JP2007291140A (ja) 2007-11-08
WO2001012840A2 (en) 2001-02-22
ES2357296T3 (es) 2011-04-25
CA2382655A1 (en) 2001-02-22
JP2003507023A (ja) 2003-02-25
AU785445C (en) 2008-01-31
EP2312316A1 (de) 2011-04-20
EP1210603A2 (de) 2002-06-05
JP4948728B2 (ja) 2012-06-06
WO2001012840B1 (en) 2001-09-27

Similar Documents

Publication Publication Date Title
ATE483978T1 (de) Anti-epha2 antikörper als krebsdiagnostikum
EP1585966B8 (de) Behandlung von Krebs mit dem anti-ErbB2-Antikörper rhuMAb 2C4
RU2005131842A (ru) Моноклональное антитело и продуцирующая его гибридома
WO2005113000A3 (en) Anti-cancer activity of an anti-thymidine kinase monoclonal antibody
RU2001102598A (ru) Способ ранней диагностики карцином
WO2000052204A3 (en) Gene expression in bladder tumors
SG170728A1 (en) Anti-tumor cell antigen antibody therapeutics
CA2384579A1 (en) Early cancer tumor marker
WO2001075177A3 (en) Tumor markers in ovarian cancer
NZ597363A (en) Prognosis prediction for colorectal cancer
WO2005016126A3 (en) Multifactorial assay for cancer detection
WO2007121465A3 (en) Detection of proteins from circulating neoplastic cells
NZ288235A (en) Monoclonal antibody directed against the receptor tyrosine kinase flt4 and use in diagnosis and therapy
WO2009019365A3 (fr) Procede de dosage de l'ezrine pour le diagnostic in vitro du cancer colorectal
WO2007098297A3 (en) Method for diagnosing and treating kidney cancer
CN101042402A (zh) 用于癌症诊断的自身抗体检测
US20130216523A1 (en) Methods for Facilitating Diagnosis, Prognosis and Treatment of Cancer by Detecting HER1 Expression
EP0163303A3 (de) Menschliche monoklonale Antikörper gegen Zelloberflächen- oder Innenzellantigene
EP1214447B8 (de) Nachweis des pyruvatkinase-isoenzyms im stuhl
DK1907842T3 (da) Identifikation af ikke-småcellede lungecarcinom-tumorer (NSCLC) udtrykkende PDGFR-alfa
WO2005114203A3 (en) Dominant b cell epitopes and methods of making and using thereof
SE9500030D0 (sv) Method of determining metastatic potential of tumor cells
ATE394676T1 (de) Verbindungen und verfahren zur diagnose von prostatakrebs
WO2006060188A3 (en) Anti-tenascin monoclonal antibody immunoassays and diagnostic kits
WO1998022825A3 (en) A whole blood/mitogen assay for the early detection of a subject with cancer and kit

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties