ATE479918T1 - Autofocus-mechanismus für ein spektroskopisches system - Google Patents

Autofocus-mechanismus für ein spektroskopisches system

Info

Publication number
ATE479918T1
ATE479918T1 AT05745517T AT05745517T ATE479918T1 AT E479918 T1 ATE479918 T1 AT E479918T1 AT 05745517 T AT05745517 T AT 05745517T AT 05745517 T AT05745517 T AT 05745517T AT E479918 T1 ATE479918 T1 AT E479918T1
Authority
AT
Austria
Prior art keywords
interest
volume
fluctuations
optical property
excitation beam
Prior art date
Application number
AT05745517T
Other languages
English (en)
Inventor
Beek Michael Cornelis Van
Gerald Lucassen
Der Voort Marjolein Van
Wouter Harry Jacinth Rensen
Vries Durk Jolmer De
Original Assignee
Koninkl Philips Electronics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Electronics Nv filed Critical Koninkl Philips Electronics Nv
Application granted granted Critical
Publication of ATE479918T1 publication Critical patent/ATE479918T1/de

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/24—Base structure
    • G02B21/241—Devices for focusing
    • G02B21/245—Devices for focusing using auxiliary sources, detectors
    • G02B21/247—Differential detectors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0237—Adjustable, e.g. focussing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N2021/6463—Optics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G01N2021/653—Coherent methods [CARS]
    • G01N2021/655—Stimulated Raman

Landscapes

  • Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Spectrometry And Color Measurement (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Microscoopes, Condenser (AREA)
AT05745517T 2004-06-17 2005-06-07 Autofocus-mechanismus für ein spektroskopisches system ATE479918T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04102769 2004-06-17
PCT/IB2005/051848 WO2005124423A1 (en) 2004-06-17 2005-06-07 Autofocus mechanism for spectroscopic system

Publications (1)

Publication Number Publication Date
ATE479918T1 true ATE479918T1 (de) 2010-09-15

Family

ID=34969886

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05745517T ATE479918T1 (de) 2004-06-17 2005-06-07 Autofocus-mechanismus für ein spektroskopisches system

Country Status (7)

Country Link
US (1) US7663748B2 (de)
EP (1) EP1761816B1 (de)
JP (1) JP5047788B2 (de)
CN (1) CN100478733C (de)
AT (1) ATE479918T1 (de)
DE (1) DE602005023305D1 (de)
WO (1) WO2005124423A1 (de)

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JP5712342B2 (ja) * 2008-11-27 2015-05-07 ナノフォトン株式会社 光学顕微鏡、及びスペクトル測定方法
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DE202010010932U1 (de) * 2010-04-19 2011-10-07 Witec Wissenschaftliche Instrumente Und Technologie Gmbh Vorrichtung zur Abbildung einer Probenoberfläche
US9522396B2 (en) 2010-12-29 2016-12-20 S.D. Sight Diagnostics Ltd. Apparatus and method for automatic detection of pathogens
JP4919307B1 (ja) * 2011-05-13 2012-04-18 レーザーテック株式会社 基板検査装置及びマスク検査装置
KR101931967B1 (ko) 2011-09-19 2018-12-27 삼성전자 주식회사 광학 현미경의 자동 초점 조절 장치
EP2798350B1 (de) 2011-12-29 2021-07-28 Sight Diagnostics Ltd. Verfahren und systeme zur erkennung eines krankheitserregers in einer biologischen probe
CN103323939A (zh) * 2012-03-20 2013-09-25 麦克奥迪实业集团有限公司 数字切片实时扫描自动聚焦***及方法
US20140118731A1 (en) * 2012-10-30 2014-05-01 Mustard Tree Instruments, Llc Adaptive Front Lens for Raman Spectroscopy Free Space Optics
EP2992826B1 (de) * 2013-05-02 2023-01-04 Atonarp Inc. Monitor und system zur überwachung lebender organismen
CN105339844B (zh) * 2013-05-21 2019-04-26 Asml荷兰有限公司 检查方法和设备、用于在其中使用的衬底及器件制造方法
WO2014188405A1 (en) 2013-05-23 2014-11-27 Parasight Ltd. Method and system for imaging a cell sample
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CN105659151B (zh) 2013-08-26 2018-06-29 思迪赛特诊断有限公司 数码显微***与方法
JP6335495B2 (ja) * 2013-12-09 2018-05-30 パナソニック デバイスＳｕｎｘ株式会社 変位センサ
WO2016030897A1 (en) 2014-08-27 2016-03-03 S.D. Sight Diagnostics Ltd System and method for calculating focus variation for a digital microscope
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FR3030787B1 (fr) * 2014-12-23 2017-01-27 Centre Nat Rech Scient Procede de re-focalisation d'un montage optique d'analyse d'echantillons
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CA2998829A1 (en) 2015-09-17 2017-03-23 S.D. Sight Diagnostics Ltd Methods and apparatus for detecting an entity in a bodily sample
CA3018536A1 (en) 2016-03-30 2017-10-05 S.D. Sight Diagnostics Ltd Distinguishing between blood sample components
CN105890753B (zh) * 2016-04-21 2017-12-01 厦门大学 拉曼光谱仪自动对焦***
EP3455610B1 (de) 2016-05-11 2023-01-04 S.D. Sight Diagnostics Ltd. Probenträger für optische messungen
CN109564209B (zh) 2016-05-11 2022-05-31 思迪赛特诊断有限公司 对样品实施的光学测量
DE102016005974B4 (de) 2016-05-13 2018-06-14 Hochschule für Technik und Wirtschaft Dresden Verfahren und Vorrichtung zur Einstellung des Laserfokus eines Anregungslasers in Blut durchflossenen Gefäßen für optische Messungen zur Bestimmung des Geschlechtes von Vogeleiern
CN106404744B (zh) * 2016-11-01 2020-07-31 北京华泰诺安技术有限公司 一种便携式指向性拉曼光谱采集***及采集方法
CN107192702B (zh) * 2017-05-23 2020-02-04 北京理工大学 分光瞳激光共焦cars显微光谱测试方法及装置
CN108956658B (zh) * 2017-05-27 2021-10-22 上海西门子医疗器械有限公司 X射线***和校准x射线管的偏转电流的方法
JP7214729B2 (ja) 2017-11-14 2023-01-30 エス．ディー．サイト ダイアグノスティクス リミテッド 光学測定用試料収容器
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Also Published As

Publication number Publication date
US20070252984A1 (en) 2007-11-01
WO2005124423A1 (en) 2005-12-29
JP5047788B2 (ja) 2012-10-10
JP2008502898A (ja) 2008-01-31
CN100478733C (zh) 2009-04-15
DE602005023305D1 (de) 2010-10-14
CN1969215A (zh) 2007-05-23
EP1761816B1 (de) 2010-09-01
US7663748B2 (en) 2010-02-16
EP1761816A1 (de) 2007-03-14

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