ATE452885T1 - Aminoarylsulfonamidderivate als funktionelle 5- ht6-liganden - Google Patents
Aminoarylsulfonamidderivate als funktionelle 5- ht6-ligandenInfo
- Publication number
- ATE452885T1 ATE452885T1 AT05813800T AT05813800T ATE452885T1 AT E452885 T1 ATE452885 T1 AT E452885T1 AT 05813800 T AT05813800 T AT 05813800T AT 05813800 T AT05813800 T AT 05813800T AT E452885 T1 ATE452885 T1 AT E452885T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- aminoarylsulfonamide
- ligands
- functional
- receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IN1127CH2005 | 2005-08-12 | ||
| PCT/IN2005/000345 WO2007020652A1 (en) | 2005-08-12 | 2005-10-26 | Aminoaryl sulphonamide derivatives as functional 5-ht6 ligands. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE452885T1 true ATE452885T1 (de) | 2010-01-15 |
Family
ID=36130030
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05813800T ATE452885T1 (de) | 2005-08-12 | 2005-10-26 | Aminoarylsulfonamidderivate als funktionelle 5- ht6-liganden |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7998981B2 (de) |
| EP (1) | EP1919896B1 (de) |
| JP (1) | JP5091138B2 (de) |
| KR (1) | KR101016972B1 (de) |
| CN (1) | CN101258144B (de) |
| AT (1) | ATE452885T1 (de) |
| AU (1) | AU2005335620B2 (de) |
| BR (1) | BRPI0520579B8 (de) |
| CA (1) | CA2618636C (de) |
| CY (1) | CY1110276T1 (de) |
| DE (1) | DE602005018554D1 (de) |
| DK (1) | DK1919896T3 (de) |
| EA (1) | EA013875B1 (de) |
| ES (1) | ES2337167T3 (de) |
| HK (1) | HK1116796A1 (de) |
| MX (1) | MX2008002018A (de) |
| NO (1) | NO340511B1 (de) |
| NZ (1) | NZ566495A (de) |
| PL (1) | PL1919896T3 (de) |
| PT (1) | PT1919896E (de) |
| SI (1) | SI1919896T1 (de) |
| WO (1) | WO2007020652A1 (de) |
| ZA (1) | ZA200801276B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2670717C (en) | 2007-01-08 | 2012-01-10 | Suven Life Sciences Limited | 5-(heterocyclyl)alkyl-n-(arylsulfonyl)indole compounds and their use as 5-ht6 ligands |
| DK2155674T3 (da) * | 2007-05-03 | 2011-09-26 | Suven Life Sciences Ltd | Aminoalkoxy-aryl-sulfonamidforbindelser og anvendelse heraf som 5-HT6-ligander |
| BRPI0816571A2 (pt) * | 2007-10-26 | 2015-12-22 | Suven Life Sciences Ltd | "composto, processo para preparação do composto, composição farmacêutica, agente e método para o tratamento de uma doença ou uma desordem do sistema nervoso central relacionada à ou afetada pelo recptor 5-ht6" |
| US8318725B2 (en) | 2008-09-17 | 2012-11-27 | Suven Life Sciences Limited | Aryl indolyl sulfonamide compounds and their use as 5-HT6 ligands |
| SG181992A1 (en) * | 2010-01-05 | 2012-08-30 | Suven Life Sciences Ltd | Sulfone compounds as 5-ht6 receptor ligands |
| CN102153884B (zh) * | 2011-02-16 | 2013-06-19 | 连云港清泰化工有限公司 | 一种墨水型染料及其制备方法与用途 |
| US9663498B2 (en) | 2013-12-20 | 2017-05-30 | Sunshine Lake Pharma Co., Ltd. | Aromatic heterocyclic compounds and their application in pharmaceuticals |
| JP6515175B2 (ja) | 2014-07-08 | 2019-05-15 | サンシャイン・レイク・ファーマ・カンパニー・リミテッドＳｕｎｓｈｉｎｅ Ｌａｋｅ Ｐｈａｒｍａ Ｃｏ．，Ｌｔｄ． | 芳香族ヘテロ環誘導体及びその医薬的適用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2126399C1 (ru) * | 1991-11-25 | 1999-02-20 | Пфайзер Инк. | Производные индола, замещенные индолы и способ ингибирования 5ht1 рецептора серотонина |
| DZ2376A1 (fr) | 1996-12-19 | 2002-12-28 | Smithkline Beecham Plc | Dérivés de sulfonamides nouveaux procédé pour leurpréparation et compositions pharmaceutiques les c ontenant. |
| JP2002511097A (ja) | 1997-07-11 | 2002-04-09 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | ５−ｈｔ▲下６▼レセプターアンタゴニストであるスルホンアミド誘導体およびその製造方法 |
| GB9801392D0 (en) | 1998-01-22 | 1998-03-18 | Smithkline Beecham Plc | Novel compounds |
| GB9803411D0 (en) | 1998-02-18 | 1998-04-15 | Smithkline Beecham Plc | Novel compounds |
| GB9926302D0 (en) | 1999-11-05 | 2000-01-12 | Smithkline Beecham Plc | Novel compounds |
| EP1355900B1 (de) * | 2000-12-22 | 2006-05-24 | Wyeth | Heterozyklylalkylindole oder -azaindole als 5-hydroxytryptamine-6 liganden |
| BR0207302A (pt) | 2001-02-08 | 2004-02-10 | Memory Pharm Corp | Trifluorometilpurinas como inibidores da fosfodiesterase 4 |
| JP2005500345A (ja) * | 2001-08-03 | 2005-01-06 | ファルマシア・アンド・アップジョン・カンパニー | ５−ｈｔ６受容体親和性を有する５−アリールスルホニルインドール |
| AU2003238339A1 (en) | 2002-02-01 | 2003-09-02 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with a new human 5-ht6 receptor |
| AU2003244452A1 (en) | 2002-02-05 | 2003-09-02 | Glaxo Group Limited | Method of promoting neuronal growth |
| DE60334972D1 (de) * | 2002-02-22 | 2010-12-30 | Pharmacia & Upjohn Co Llc | Pyridylsulfon-derivate als 5-ht6 rezeptor liganden |
| CA2485725A1 (en) * | 2002-06-05 | 2003-12-18 | F. Hoffmann-La Roche Ag | 1-sulfonyl-4-aminoalkoxy indole derivatives as 5-ht6-receptor modulators for the treatment of cns-disorders |
| KR20050073560A (ko) | 2002-10-18 | 2005-07-14 | 에프. 호프만-라 로슈 아게 | 5-ｈｔ6 수용체 친화성을 갖는 4-피페라진일 벤젠설폰일인돌 |
| NZ540842A (en) | 2002-11-28 | 2008-05-30 | Suven Life Sciences Ltd | N-arylsulfonyl-3-aminoalkoxyindoles |
| AU2003292508A1 (en) | 2002-11-28 | 2004-06-18 | Suven Life Sciences Limited | N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands |
| AU2003237599B2 (en) | 2002-11-28 | 2009-06-18 | Suven Life Sciences Limited | N-arylsulfonyl-3-substituted indoles having serotonin receptor affinity, process for their preparation and pharmaceutical composition containing them |
| DK1581538T3 (da) | 2002-12-18 | 2007-06-25 | Suven Life Sciences Ltd | Tetracykliske 3-substituerede indoler med serotoninreceptoraffinitet |
| ATE551997T1 (de) * | 2003-09-12 | 2012-04-15 | Merck Serono Sa | Sulfonamid-derivate zur behandlung von diabetes |
-
2005
- 2005-10-26 EP EP05813800A patent/EP1919896B1/de active Active
- 2005-10-26 NZ NZ566495A patent/NZ566495A/en not_active IP Right Cessation
- 2005-10-26 PL PL05813800T patent/PL1919896T3/pl unknown
- 2005-10-26 SI SI200530928T patent/SI1919896T1/sl unknown
- 2005-10-26 DK DK05813800.9T patent/DK1919896T3/da active
- 2005-10-26 BR BRPI0520579A patent/BRPI0520579B8/pt not_active IP Right Cessation
- 2005-10-26 CA CA2618636A patent/CA2618636C/en not_active Expired - Fee Related
- 2005-10-26 AT AT05813800T patent/ATE452885T1/de active
- 2005-10-26 WO PCT/IN2005/000345 patent/WO2007020652A1/en active Application Filing
- 2005-10-26 US US11/990,383 patent/US7998981B2/en not_active Expired - Fee Related
- 2005-10-26 ES ES05813800T patent/ES2337167T3/es active Active
- 2005-10-26 CN CN2005800515505A patent/CN101258144B/zh not_active Expired - Fee Related
- 2005-10-26 AU AU2005335620A patent/AU2005335620B2/en not_active Ceased
- 2005-10-26 EA EA200800573A patent/EA013875B1/ru not_active IP Right Cessation
- 2005-10-26 JP JP2008525723A patent/JP5091138B2/ja not_active Expired - Fee Related
- 2005-10-26 MX MX2008002018A patent/MX2008002018A/es active IP Right Grant
- 2005-10-26 PT PT05813800T patent/PT1919896E/pt unknown
- 2005-10-26 DE DE602005018554T patent/DE602005018554D1/de active Active
- 2005-10-26 KR KR1020087005968A patent/KR101016972B1/ko active IP Right Grant
-
2008
- 2008-02-06 ZA ZA200801276A patent/ZA200801276B/xx unknown
- 2008-02-08 NO NO20080705A patent/NO340511B1/no not_active IP Right Cessation
- 2008-10-15 HK HK08111412.9A patent/HK1116796A1/xx not_active IP Right Cessation
-
2010
- 2010-02-04 CY CY20101100110T patent/CY1110276T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0520579A2 (pt) | 2009-11-10 |
| EA200800573A1 (ru) | 2008-08-29 |
| JP2009504633A (ja) | 2009-02-05 |
| MX2008002018A (es) | 2008-03-27 |
| US7998981B2 (en) | 2011-08-16 |
| JP5091138B2 (ja) | 2012-12-05 |
| PL1919896T3 (pl) | 2010-05-31 |
| DK1919896T3 (da) | 2010-04-19 |
| AU2005335620A1 (en) | 2007-02-22 |
| CN101258144B (zh) | 2012-05-30 |
| WO2007020652A1 (en) | 2007-02-22 |
| BRPI0520579B1 (pt) | 2019-08-06 |
| ES2337167T3 (es) | 2010-04-21 |
| EP1919896A1 (de) | 2008-05-14 |
| HK1116796A1 (en) | 2009-01-02 |
| CY1110276T1 (el) | 2015-01-14 |
| DE602005018554D1 (de) | 2010-02-04 |
| KR101016972B1 (ko) | 2011-02-25 |
| EA013875B1 (ru) | 2010-08-30 |
| NO340511B1 (no) | 2017-05-02 |
| ZA200801276B (en) | 2009-02-25 |
| NZ566495A (en) | 2010-06-25 |
| CA2618636C (en) | 2011-01-18 |
| NO20080705L (no) | 2008-05-06 |
| BRPI0520579B8 (pt) | 2021-05-25 |
| KR20080039984A (ko) | 2008-05-07 |
| CA2618636A1 (en) | 2007-02-22 |
| EP1919896B1 (de) | 2009-12-23 |
| AU2005335620B2 (en) | 2009-12-10 |
| SI1919896T1 (sl) | 2010-04-30 |
| PT1919896E (pt) | 2010-02-26 |
| US20100168168A1 (en) | 2010-07-01 |
| CN101258144A (zh) | 2008-09-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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