ATE445641T1 - Glucagon ähnliche peptide-2 und ihre therapeutische verwendung - Google Patents
Glucagon ähnliche peptide-2 und ihre therapeutische verwendungInfo
- Publication number
- ATE445641T1 ATE445641T1 AT96908973T AT96908973T ATE445641T1 AT E445641 T1 ATE445641 T1 AT E445641T1 AT 96908973 T AT96908973 T AT 96908973T AT 96908973 T AT96908973 T AT 96908973T AT E445641 T1 ATE445641 T1 AT E445641T1
- Authority
- AT
- Austria
- Prior art keywords
- glucagon
- peptide
- therapeutic use
- bowel
- analogs
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/605—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/605—Glucagons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Obesity (AREA)
- Microbiology (AREA)
- Emergency Medicine (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Pain & Pain Management (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/422,540 US5990077A (en) | 1995-04-14 | 1995-04-14 | Glucagon-like peptide-2 and its therapeutic use |
PCT/CA1996/000232 WO1996032414A1 (en) | 1995-04-14 | 1996-04-12 | Glucagon-like peptide-2 and its therapeutic use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE445641T1 true ATE445641T1 (de) | 2009-10-15 |
Family
ID=23675346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96908973T ATE445641T1 (de) | 1995-04-14 | 1996-04-12 | Glucagon ähnliche peptide-2 und ihre therapeutische verwendung |
Country Status (13)
Country | Link |
---|---|
US (1) | US5990077A (de) |
EP (4) | EP2277530A1 (de) |
JP (3) | JPH11505521A (de) |
CN (2) | CN100374461C (de) |
AT (1) | ATE445641T1 (de) |
AU (1) | AU720493B2 (de) |
CA (1) | CA2218225C (de) |
CY (1) | CY2615B2 (de) |
DE (1) | DE69638057D1 (de) |
DK (1) | DK0830377T4 (de) |
ES (1) | ES2334864T5 (de) |
PT (1) | PT830377E (de) |
WO (1) | WO1996032414A1 (de) |
Families Citing this family (85)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5990077A (en) | 1995-04-14 | 1999-11-23 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
US6184201B1 (en) * | 1995-04-14 | 2001-02-06 | Nps Allelix Corp. | Intestinotrophic glucagon-like peptide-2 analogs |
US5834428A (en) * | 1995-04-14 | 1998-11-10 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
US5912229A (en) * | 1996-03-01 | 1999-06-15 | Novo Nordisk Als | Use of a pharmaceutical composition comprising an appetite-suppressing peptide |
CZ297338B6 (cs) | 1996-03-01 | 2006-11-15 | Novo Nordisk A/S | Peptid potlacující chut k jídlu, farmaceutický prostredek jej obsahující a jeho pouzití |
DE69716905T2 (de) * | 1996-04-12 | 2003-07-24 | 1149336 Ontario Inc., Toronto | Analoge des glucagon ähnlichen peptides -2 |
AU753771B2 (en) * | 1996-04-12 | 2002-10-31 | 1149336 Ontario Inc. | Glucagon-like peptide-2 analogs |
US5994500A (en) * | 1996-07-19 | 1999-11-30 | 1149336 Ontario Inc. | Antagonists of intestinotrophic GLP-2 peptides |
US20020025933A1 (en) * | 1996-08-30 | 2002-02-28 | Knudsen Liselotte Bjerre | GLP-2 derivatives |
WO1998008872A1 (en) * | 1996-08-30 | 1998-03-05 | Novo Nordisk A/S | Glp-2 derivatives |
US5952301A (en) * | 1996-12-10 | 1999-09-14 | 1149336 Ontario Inc. | Compositions and methods for enhancing intestinal function |
DE69737561T2 (de) * | 1996-12-13 | 2008-03-06 | Nps Allelix Corp., Toronto | Klonierte rezeptoren des glukagon-ähnlichen peptids-2 |
US8592553B2 (en) | 1996-12-13 | 2013-11-26 | Nps Pharmaceuticals, Inc. | Cloned glucagon-like peptide-2 receptors |
CA2236519C (en) | 1997-05-02 | 2011-09-13 | 1149336 Ontario Inc. | Methods of enhancing functioning of the large intestine |
CA2289652C (en) * | 1997-05-16 | 2012-02-28 | 1149336 Ontario Inc. | Methods of enhancing functioning of the upper gastrointestinal tract |
EP1060192A2 (de) * | 1998-02-27 | 2000-12-20 | Novo Nordisk A/S | Glp-2 derivate mit einem helixgehalt über 25%, die partiell strukturierte mizellenartige aggregate bilden |
US6444788B1 (en) | 1999-03-15 | 2002-09-03 | Novo Nordisk A/S | Ion exchange chromatography of GLP-1, analogs and derivatives thereof |
US6451987B1 (en) | 1999-03-15 | 2002-09-17 | Novo Nordisk A/S | Ion exchange chromatography of proteins and peptides |
ATE509028T1 (de) | 1999-03-15 | 2011-05-15 | Novo Nordisk As | Ionen-austausch-chromatographische trennung von glp-1 und verwandten peptiden |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
US7186683B2 (en) | 2000-09-18 | 2007-03-06 | Sanos Bioscience A/S | Use of GLP for the treatment, prevention, diagnosis, and prognosis of bone-related and nutrition-related disorders |
US7371721B2 (en) * | 2000-09-18 | 2008-05-13 | Sanos Bioscience A/S | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes |
US20080249016A1 (en) * | 2000-09-18 | 2008-10-09 | Sanos Bioscience A/S | Use of GLP-2 in a combination treatment for bone-related disorders |
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KR0154880B1 (ko) * | 1992-06-15 | 1998-10-15 | 피터 알.셰어러 | 글루카곤-유사 펩티드 및 인슐리노트로핀 유도체 |
JP2961045B2 (ja) * | 1993-02-24 | 1999-10-12 | 日清製粉株式会社 | 腸管粘膜増強促進剤 |
US5990077A (en) | 1995-04-14 | 1999-11-23 | 1149336 Ontario Inc. | Glucagon-like peptide-2 and its therapeutic use |
CZ297338B6 (cs) | 1996-03-01 | 2006-11-15 | Novo Nordisk A/S | Peptid potlacující chut k jídlu, farmaceutický prostredek jej obsahující a jeho pouzití |
DE69716905T2 (de) * | 1996-04-12 | 2003-07-24 | 1149336 Ontario Inc., Toronto | Analoge des glucagon ähnlichen peptides -2 |
-
1995
- 1995-04-14 US US08/422,540 patent/US5990077A/en not_active Expired - Lifetime
-
1996
- 1996-04-12 PT PT96908973T patent/PT830377E/pt unknown
- 1996-04-12 JP JP8530606A patent/JPH11505521A/ja not_active Withdrawn
- 1996-04-12 EP EP10012215A patent/EP2277530A1/de not_active Withdrawn
- 1996-04-12 EP EP96908973A patent/EP0830377B2/de not_active Expired - Lifetime
- 1996-04-12 CN CNB961946938A patent/CN100374461C/zh not_active Expired - Lifetime
- 1996-04-12 CA CA2218225A patent/CA2218225C/en not_active Expired - Lifetime
- 1996-04-12 AU AU52658/96A patent/AU720493B2/en not_active Expired
- 1996-04-12 EP EP10012214A patent/EP2277909A1/de not_active Withdrawn
- 1996-04-12 AT AT96908973T patent/ATE445641T1/de active
- 1996-04-12 DK DK96908973.9T patent/DK0830377T4/da active
- 1996-04-12 EP EP08154372.0A patent/EP1988100B1/de not_active Expired - Lifetime
- 1996-04-12 DE DE69638057T patent/DE69638057D1/de not_active Expired - Lifetime
- 1996-04-12 ES ES96908973T patent/ES2334864T5/es not_active Expired - Lifetime
- 1996-04-12 CN CN2008100012906A patent/CN101254300B/zh not_active Expired - Lifetime
- 1996-04-12 WO PCT/CA1996/000232 patent/WO1996032414A1/en active Application Filing
-
2006
- 2006-07-05 JP JP2006185610A patent/JP4496183B2/ja not_active Expired - Lifetime
-
2010
- 2010-01-25 JP JP2010012787A patent/JP5281594B2/ja not_active Expired - Lifetime
-
2011
- 2011-04-15 CY CY1100004A patent/CY2615B2/xx unknown
Also Published As
Publication number | Publication date |
---|---|
CN101254300A (zh) | 2008-09-03 |
JP2010159259A (ja) | 2010-07-22 |
EP0830377A1 (de) | 1998-03-25 |
DK0830377T4 (da) | 2013-03-11 |
CY2615B2 (en) | 2012-01-25 |
ES2334864T3 (es) | 2010-03-16 |
CN101254300B (zh) | 2013-05-08 |
AU720493B2 (en) | 2000-06-01 |
PT830377E (pt) | 2010-01-19 |
EP0830377B2 (de) | 2012-12-12 |
JP5281594B2 (ja) | 2013-09-04 |
MX9707949A (es) | 1998-06-30 |
JP4496183B2 (ja) | 2010-07-07 |
DK0830377T3 (da) | 2010-03-01 |
US5990077A (en) | 1999-11-23 |
EP0830377B1 (de) | 2009-10-14 |
JPH11505521A (ja) | 1999-05-21 |
JP2006342172A (ja) | 2006-12-21 |
EP1988100A1 (de) | 2008-11-05 |
CN100374461C (zh) | 2008-03-12 |
DE69638057D1 (de) | 2009-11-26 |
EP2277909A1 (de) | 2011-01-26 |
EP1988100B1 (de) | 2015-03-04 |
CA2218225C (en) | 2014-09-23 |
WO1996032414A1 (en) | 1996-10-17 |
AU5265896A (en) | 1996-10-30 |
CA2218225A1 (en) | 1996-10-17 |
ES2334864T5 (es) | 2013-04-08 |
CN1188485A (zh) | 1998-07-22 |
EP2277530A1 (de) | 2011-01-26 |
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