ATE445010T1 - Stellenspezifisches system zur erstellung vielfältiger proteinsequenzen - Google Patents
Stellenspezifisches system zur erstellung vielfältiger proteinsequenzenInfo
- Publication number
- ATE445010T1 ATE445010T1 AT05804058T AT05804058T ATE445010T1 AT E445010 T1 ATE445010 T1 AT E445010T1 AT 05804058 T AT05804058 T AT 05804058T AT 05804058 T AT05804058 T AT 05804058T AT E445010 T1 ATE445010 T1 AT E445010T1
- Authority
- AT
- Austria
- Prior art keywords
- site
- nucleic acid
- protein sequences
- specific system
- diverse protein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1024—In vivo mutagenesis using high mutation rate "mutator" host strains by inserting genetic material, e.g. encoding an error prone polymerase, disrupting a gene for mismatch repair
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
Landscapes
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Plant Pathology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Ecology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US59861704P | 2004-08-03 | 2004-08-03 | |
PCT/US2005/027625 WO2006015370A2 (en) | 2004-08-03 | 2005-08-03 | Site specific system for generating diversity protein sequences |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE445010T1 true ATE445010T1 (de) | 2009-10-15 |
Family
ID=35787926
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05804058T ATE445010T1 (de) | 2004-08-03 | 2005-08-03 | Stellenspezifisches system zur erstellung vielfältiger proteinsequenzen |
Country Status (9)
Country | Link |
---|---|
US (1) | US7585957B2 (de) |
EP (1) | EP1773995B1 (de) |
JP (1) | JP2008508879A (de) |
CN (1) | CN101090967A (de) |
AT (1) | ATE445010T1 (de) |
AU (1) | AU2005267719B2 (de) |
CA (1) | CA2575533C (de) |
DE (1) | DE602005017042D1 (de) |
WO (1) | WO2006015370A2 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7749694B2 (en) * | 2004-12-31 | 2010-07-06 | The Regents Of The University Of California | C-type lectin fold as a scaffold for massive sequence variation |
US7700729B2 (en) * | 2006-05-15 | 2010-04-20 | Avidbiotics Corporation | Modified bacteriocins and methods for their use |
US8445639B2 (en) | 2006-05-15 | 2013-05-21 | Avidbiotics Corporation | Recombinant bacteriophage and methods for their use |
ES2387722T3 (es) * | 2006-05-15 | 2012-09-28 | Avidbiotics Corporation | Bacteriocinas modificadas y métodos para su uso |
EP4368202A2 (de) | 2007-03-30 | 2024-05-15 | The Research Foundation for The State University of New York | Attenuierte viren für impfstoffe |
WO2009094006A2 (en) | 2007-10-25 | 2009-07-30 | Wake Forest University Health Sciences | Bordetella outer-membrane protein antigens and methods of making and using the same |
WO2012091756A1 (en) | 2010-12-30 | 2012-07-05 | Avidbiotics Corp. | Non-natural mic proteins |
BR112012030083A2 (pt) | 2010-05-27 | 2017-05-02 | Avidbiotics Corp | difocinas e seus métodos de uso |
US9115354B2 (en) | 2010-05-27 | 2015-08-25 | Avidbiotics Corp. | Diffocins and methods of use thereof |
JP2016512428A (ja) | 2013-03-14 | 2016-04-28 | アビッドバイオティクス コーポレイション | ディフォシン及びその使用方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6165718A (en) * | 1996-01-10 | 2000-12-26 | Novo Nordisk A/S Novo Alle | Method for in vivo production of a mutant library in cells |
IL162462A0 (en) * | 2001-12-14 | 2005-11-20 | Univ Yale | Intracellular generation of single-stranded dna |
EP1517992B1 (de) | 2002-06-05 | 2013-08-21 | Her Majesty the Queen in Right of Canada, as represented by the Minister of Agriculture and Agri-Food | Retrons für gen-targeting |
AU2003258658A1 (en) | 2002-08-29 | 2004-03-19 | Andreas Beck | Improved dna and proteins |
-
2005
- 2005-08-03 US US11/197,219 patent/US7585957B2/en active Active
- 2005-08-03 DE DE602005017042T patent/DE602005017042D1/de active Active
- 2005-08-03 JP JP2007524959A patent/JP2008508879A/ja active Pending
- 2005-08-03 CA CA2575533A patent/CA2575533C/en not_active Expired - Fee Related
- 2005-08-03 CN CNA2005800329446A patent/CN101090967A/zh active Pending
- 2005-08-03 EP EP05804058A patent/EP1773995B1/de not_active Not-in-force
- 2005-08-03 WO PCT/US2005/027625 patent/WO2006015370A2/en active Application Filing
- 2005-08-03 AU AU2005267719A patent/AU2005267719B2/en not_active Ceased
- 2005-08-03 AT AT05804058T patent/ATE445010T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US7585957B2 (en) | 2009-09-08 |
CA2575533A1 (en) | 2006-02-09 |
JP2008508879A (ja) | 2008-03-27 |
DE602005017042D1 (de) | 2009-11-19 |
CN101090967A (zh) | 2007-12-19 |
US20060121450A1 (en) | 2006-06-08 |
AU2005267719A1 (en) | 2006-02-09 |
EP1773995B1 (de) | 2009-10-07 |
AU2005267719B2 (en) | 2010-12-23 |
EP1773995A2 (de) | 2007-04-18 |
WO2006015370A3 (en) | 2006-08-17 |
CA2575533C (en) | 2014-11-18 |
WO2006015370A2 (en) | 2006-02-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE445010T1 (de) | Stellenspezifisches system zur erstellung vielfältiger proteinsequenzen | |
DE60230672D1 (de) | Nukleinsäureanreicherung | |
BR0315652A (pt) | Molécula de ácido nucleico isolada, vetor, sistema de vetor-hospedeiro, método de produção de um polipeptìdeo de fusão, ácido nucleico isolado, polipeptìdeo de fusão, e, multìmero | |
WO2006040549A2 (en) | Labelling and sequencing of nucleic acids | |
WO2014162307A8 (en) | Methods and apparatus for synthesizing nucleic acids | |
MX2007003167A (es) | Asministracion de polinucleotidos. | |
MX2021000209A (es) | Metodos y productos para transfeccion de celulas. | |
EP2514826A3 (de) | Verwendung von interferierendem RNA zur Herabregulation von spezifischen Genen oder Genenfamilie | |
WO2009076485A3 (en) | Sequencing of nucleic acids | |
ATE407939T1 (de) | 2ß-NITROBENZYL-MODIFIZIERTE RIBONUKLEOTIDE | |
NZ600183A (en) | Method for efficient exon (44) skipping in duchenne muscular dystrophy and associated means | |
NZ543467A (en) | The severe acute respiratory syndrome coronavirus | |
EA200702278A1 (ru) | Антитела, специфичные в отношении tgf-бета 1 | |
NZ717429A (en) | Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly | |
WO2005017205A3 (en) | Nucleic acid mapping using linear analysis | |
WO2009097626A3 (en) | Paired-end reads in sequencing by synthesis | |
MX2019007248A (es) | Enzimas de polimerizacion para reacciones de secuenciacion. | |
IN2012DN02345A (de) | ||
WO2008112980A3 (en) | Method and system for assembly of macromolecules and nanostructures | |
FR2804971B1 (fr) | Adn codant une acetohydroxyacide synthase, bacterie le contenant et procede de production de l-valine par culture de cette bacterie | |
DE602006009901D1 (de) | Verfahren zur herstellung von 7-ethyl-10-hydroxycamptothecin | |
ATE533837T1 (de) | Microginin-produzierende proteine und nukleinsäuren, einen microginin gen-cluster kodierend, sowie methoden zur herstellung von microgininen | |
EP1984013A4 (de) | Cst-ii-modifzierungen für erhöhte proteinexpression | |
CO5650177A2 (es) | Constructos geneticos y composiciones que comprenden rre y cte y usos de estos | |
ATE413413T1 (de) | Methode zur produktion von faktor g des pfeilschwanzkrebses (limulus) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |