ATE419235T1 - Trizyklische antidepressiva und immunoassay - Google Patents

Trizyklische antidepressiva und immunoassay

Info

Publication number
ATE419235T1
ATE419235T1 AT01130018T AT01130018T ATE419235T1 AT E419235 T1 ATE419235 T1 AT E419235T1 AT 01130018 T AT01130018 T AT 01130018T AT 01130018 T AT01130018 T AT 01130018T AT E419235 T1 ATE419235 T1 AT E419235T1
Authority
AT
Austria
Prior art keywords
tricyclic antidepressant
novel
substituted
derivatives
sub
Prior art date
Application number
AT01130018T
Other languages
English (en)
Inventor
Mitali Ghoshal
Jane S C Tsai
Stephen Vitone
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE419235T1 publication Critical patent/ATE419235T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/815—Test for named compound or class of compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT01130018T 2000-12-22 2001-12-18 Trizyklische antidepressiva und immunoassay ATE419235T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/747,809 US6368814B1 (en) 2000-12-22 2000-12-22 Tricyclic antidepressant derivatives and immunoassay

Publications (1)

Publication Number Publication Date
ATE419235T1 true ATE419235T1 (de) 2009-01-15

Family

ID=25006733

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01130018T ATE419235T1 (de) 2000-12-22 2001-12-18 Trizyklische antidepressiva und immunoassay

Country Status (6)

Country Link
US (1) US6368814B1 (de)
EP (1) EP1216994B1 (de)
JP (2) JP3899260B2 (de)
AT (1) ATE419235T1 (de)
DE (1) DE60137186D1 (de)
ES (1) ES2319257T3 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6368814B1 (en) * 2000-12-22 2002-04-09 Roche Diagnostics Corporation Tricyclic antidepressant derivatives and immunoassay
US20020188342A1 (en) * 2001-06-01 2002-12-12 Rykhus Robert L. Short-term bioresorbable stents
US7585627B2 (en) * 2004-05-21 2009-09-08 Duke University Polymorphism in tryptophan hydroxylase-2 controls brain serotonin synthesis
AU2008267360B2 (en) * 2007-06-26 2013-09-12 Takeda Pharmaceutical Company Limited Hydrolysable polymeric Fmoc-linker
WO2010013240A1 (en) 2008-07-31 2010-02-04 Dekel Pharmaceuticals Ltd. Compositions and methods for treating inflammatory disorders
WO2012054815A1 (en) 2010-10-22 2012-04-26 Duke University Slow-release formulations of 5-hydroxytryptophan as an adjunct to pro-serotonergic therapies
KR101919330B1 (ko) * 2011-06-16 2018-11-19 후지필름 가부시키가이샤 고감도의 면역크로마토그래프 방법 및 면역크로마토그래프용 키트
GB201110164D0 (en) 2011-06-16 2011-07-27 Randox Lab Ltd Sensitive and generic antibodies with multiple applications
CN108588032A (zh) * 2018-04-25 2018-09-28 青岛汉德森生物科技有限公司 杂交瘤细胞株及其制备方法、三环类抗抑郁药单克隆抗体及试剂盒

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4495281A (en) * 1982-10-21 1985-01-22 Miles Laboratories, Inc. Tricyclic antidepressant drug immunogens, antibodies, labeled conjugates, and related derivatives
US4629691A (en) * 1983-08-01 1986-12-16 Syntex (U.S.A.) Inc. Tricyclic antidepressant conjugates with antigens and enzymes
US4795822A (en) * 1984-05-23 1989-01-03 Syntex (U.S.A.) Inc. Nortriptyline conjugates to antigenic proteins and enzymes
EP0226730B1 (de) 1985-10-15 1994-03-02 Abbott Laboratories Verbindungen und Immunoassay für tricyclische Antidepressiva
ES2104566T3 (es) * 1989-03-10 1997-10-16 Hoffmann La Roche Reactivos para la determinacion de drogas.
GB9001694D0 (en) * 1990-01-25 1990-03-28 Therapeutic Antibodies Inc Immunogenic compositions
US5413911A (en) * 1990-12-14 1995-05-09 Abbott Laboratories Determination of tricyclic antidepressant drugs in the presence of interfering substances
US5340750A (en) * 1991-07-31 1994-08-23 Abbott Laboratories Reagents and methods for the quantification of imipramine or desipramine in biological fluids
US5407835A (en) * 1991-07-31 1995-04-18 Abbott Laboratories Reagents and methods for the quantification of amitriptyline or nortriptyline in biological fluids
DE69316112T2 (de) * 1992-08-07 1998-06-10 Johnson & Johnson Clin Diag Immunoassays unter Verwendung von, mit Meerrettich-Peroxidase markierten Carbamazepin-Analogen
US5578457A (en) * 1992-08-07 1996-11-26 Johnson & Johnson Clinical Diagnostics, Inc. Immunoassays with novel labeled carbamazepine hapten analogues
US6803040B1 (en) * 1995-08-22 2004-10-12 Biosite, Inc. Derivatives of tricyclic antidepressants and protein and polypeptide tricyclic antidepressant derivative conjugates and labels
US6368814B1 (en) * 2000-12-22 2002-04-09 Roche Diagnostics Corporation Tricyclic antidepressant derivatives and immunoassay

Also Published As

Publication number Publication date
DE60137186D1 (de) 2009-02-12
ES2319257T3 (es) 2009-05-06
US6368814B1 (en) 2002-04-09
JP2002302471A (ja) 2002-10-18
JP4570601B2 (ja) 2010-10-27
EP1216994A2 (de) 2002-06-26
JP2007056030A (ja) 2007-03-08
JP3899260B2 (ja) 2007-03-28
EP1216994A3 (de) 2003-03-26
EP1216994B1 (de) 2008-12-31

Similar Documents

Publication Publication Date Title
JP2894782B2 (ja) アンフェタミン様分析対象物の検出のための蛍光偏光イムノアッセイ法およびそれに用いるアッセイキット
EP0279213B1 (de) Fluoreszenzpolarisationsimmunassay für Amphetamin/Methamphetamin
US4495281A (en) Tricyclic antidepressant drug immunogens, antibodies, labeled conjugates, and related derivatives
DE69325096D1 (de) Morphinderivate sowie deren konjugate und labels mit proteinen und polypeptiden
DE58907232D1 (de) Neue Digoxigenin-Derivate und ihre Verwendung.
KR900002803A (ko) 세포독성 약물 결합체
JP2005514430A (ja) 抗体ターゲッティング化合物
DE60137186D1 (de) Trizyklische Antidepressiva und Immunoassay
JP2007161712A (ja) 免疫アッセイに有用な６−モノアセチルモルヒネ誘導体
US4952336A (en) Fluorescence polymerization immunoassay for amphetamine/methamphetamine
US5302703A (en) Tetrahydrocannabinol derivatives and protein and polypeptide tetrahydrocannabinol derivative conjugates and labels
ES2095840T3 (es) Conjugado de anticuerpo-farmaco.
EP0638067B1 (de) Neue propoxyphenderivate sowie deren protein-und polypeptidlabels und-konjugate
CA1250099A (en) Immunogens, antibodies, labeled conjugates and related derivatives for lidocaine and analogs thereof
US7271252B2 (en) Reagents for detecting efavirenz
US5106762A (en) Ligand-label conjugates which contain polyoxoanions of sulfur or phosphorus
JP4369814B2 (ja) エクスタシークラス誘導体、免疫原、および抗体ならびにエクスタシークラス薬物の検出におけるそれらの使用
RU98115277A (ru) Антитела с уменьшенным суммарным положительным зарядом
US10775394B2 (en) Immunoassay for phenethylamines of the 2C and DO sub-families
JPH08333396A (ja) 免疫検定試薬用プロポキシフェン誘導体
US6803040B1 (en) Derivatives of tricyclic antidepressants and protein and polypeptide tricyclic antidepressant derivative conjugates and labels
ES2152229T3 (es) Reactivos y procedimientos de cuantificacion de la amitriptilina o de la nortriptilina en fluidos biologicos.
WO1996040664A3 (en) Preparation of immunogens and other conjugates of drugs
US20180237380A1 (en) Immunoassay
Hirose et al. Syntheses of antigens conjugated with 3-methoxy-4-hydroxyphenylglycol by Mannich reaction for enzyme immunoassay

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1216994

Country of ref document: EP