ATE417817T1 - Verfahren zur herstellung eines optisch aktiven amids ausgehend von einem alpha, beta- ungesättigtem amid derivat in anwesenheit eines optisch aktiven übergangsmetallkomplexes, der eine phosphin-phosphoran verbindung und rhodium enthält - Google Patents
Verfahren zur herstellung eines optisch aktiven amids ausgehend von einem alpha, beta- ungesättigtem amid derivat in anwesenheit eines optisch aktiven übergangsmetallkomplexes, der eine phosphin-phosphoran verbindung und rhodium enthältInfo
- Publication number
- ATE417817T1 ATE417817T1 AT02291876T AT02291876T ATE417817T1 AT E417817 T1 ATE417817 T1 AT E417817T1 AT 02291876 T AT02291876 T AT 02291876T AT 02291876 T AT02291876 T AT 02291876T AT E417817 T1 ATE417817 T1 AT E417817T1
- Authority
- AT
- Austria
- Prior art keywords
- optically active
- beta
- alpha
- amide
- producing
- Prior art date
Links
- 150000001408 amides Chemical class 0.000 title abstract 6
- -1 PHOSPHINE-PHOSPHORANE COMPOUND Chemical class 0.000 title abstract 2
- 229910052723 transition metal Inorganic materials 0.000 title abstract 2
- 150000003624 transition metals Chemical class 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 229910052703 rhodium Inorganic materials 0.000 title 1
- 239000010948 rhodium Substances 0.000 title 1
- MHOVAHRLVXNVSD-UHFFFAOYSA-N rhodium atom Chemical compound [Rh] MHOVAHRLVXNVSD-UHFFFAOYSA-N 0.000 title 1
- 238000009876 asymmetric hydrogenation reaction Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6568—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus atoms as the only ring hetero atoms
- C07F9/65683—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus atoms as the only ring hetero atoms the ring phosphorus atom being part of a phosphine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001222421 | 2001-07-24 | ||
JP2002168014A JP4226847B2 (ja) | 2001-07-24 | 2002-06-10 | ホスフィン−ホスホラン化合物と遷移金属とを含有する遷移金属錯体の存在下、α,β−不飽和アミド誘導体から光学活性アミド類を製造する方法。 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE417817T1 true ATE417817T1 (de) | 2009-01-15 |
Family
ID=26619144
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02291876T ATE417817T1 (de) | 2001-07-24 | 2002-07-24 | Verfahren zur herstellung eines optisch aktiven amids ausgehend von einem alpha, beta- ungesättigtem amid derivat in anwesenheit eines optisch aktiven übergangsmetallkomplexes, der eine phosphin-phosphoran verbindung und rhodium enthält |
Country Status (5)
Country | Link |
---|---|
US (1) | US6855847B2 (de) |
EP (1) | EP1279660B1 (de) |
JP (1) | JP4226847B2 (de) |
AT (1) | ATE417817T1 (de) |
DE (1) | DE60230366D1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4005800B2 (ja) * | 2001-12-10 | 2007-11-14 | 高砂香料工業株式会社 | 新規不斉ホスフィン配位子 |
JP4005801B2 (ja) | 2001-12-10 | 2007-11-14 | 高砂香料工業株式会社 | 新規なホスフィン配位子 |
CN100349907C (zh) * | 2003-05-09 | 2007-11-21 | 索尔维亚斯股份公司 | 膦烷盐及其在对映选择性氢化中的用途 |
DE102005014055A1 (de) * | 2005-03-23 | 2006-09-28 | Degussa Ag | Unsymmetrisch substituierte Phospholankatalysatoren |
WO2020194337A2 (en) * | 2019-03-28 | 2020-10-01 | Council Of Scientific And Industrial Research | A process for the asymmetric synthesis of sitagliptin intermediate |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5008457A (en) | 1990-05-17 | 1991-04-16 | E. I. Du Pont De Nemours And Company | Chiral phospholane transition metal catalysts |
US5171892A (en) | 1991-07-02 | 1992-12-15 | E. I. Du Pont De Nemours And Company | Chiral phospholanes via chiral 1,4-diol cyclic sulfates |
WO1999059721A1 (en) | 1998-05-18 | 1999-11-25 | The Penn State Research Foundation | Catalytic asymmetric hydrogenation, hydroformylation, and hydrovinylation via transition metal catalysts with phosphines and phosphites |
EP1105400A1 (de) | 1998-08-21 | 2001-06-13 | The Penn State Research Foundation | Asymmetrische katalysis mit hilfe von chiralen phospholanen |
GB9823716D0 (en) | 1998-10-29 | 1998-12-23 | Isis Innovation | Diphosphines |
DE19956414A1 (de) | 1999-11-24 | 2001-06-13 | Aventis Res & Tech Gmbh & Co | Verfahren zur Herstellung von chiralen Aminen durch homogen katalysierte asymmetrische Hydrierung von Enaminen |
DE10100971A1 (de) * | 2001-01-11 | 2002-07-18 | Degussa | Verfahren zur Herstellung enantiomerenangereicherter beta-Aminosäure |
JP4005800B2 (ja) * | 2001-12-10 | 2007-11-14 | 高砂香料工業株式会社 | 新規不斉ホスフィン配位子 |
JP4005801B2 (ja) * | 2001-12-10 | 2007-11-14 | 高砂香料工業株式会社 | 新規なホスフィン配位子 |
-
2002
- 2002-06-10 JP JP2002168014A patent/JP4226847B2/ja not_active Expired - Fee Related
- 2002-07-22 US US10/198,930 patent/US6855847B2/en not_active Expired - Fee Related
- 2002-07-24 AT AT02291876T patent/ATE417817T1/de not_active IP Right Cessation
- 2002-07-24 DE DE60230366T patent/DE60230366D1/de not_active Expired - Lifetime
- 2002-07-24 EP EP02291876A patent/EP1279660B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP2003104946A (ja) | 2003-04-09 |
EP1279660B1 (de) | 2008-12-17 |
DE60230366D1 (de) | 2009-01-29 |
US6855847B2 (en) | 2005-02-15 |
JP4226847B2 (ja) | 2009-02-18 |
US20030120067A1 (en) | 2003-06-26 |
EP1279660A1 (de) | 2003-01-29 |
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