ATE414088T1 - Polymorphe formen eines gabaa-agonisten - Google Patents

Polymorphe formen eines gabaa-agonisten

Info

Publication number: ATE414088T1
Authority: AT; Austria
Prior art keywords: polymorphoic; forms; gabaa agonist; gabaa; agonist
Prior art date: 2004-01-30

Application number

AT05702040T

Other languages

English (en)

Inventor

Vincent Brett Cooper

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-01-30

Filing date

2005-01-28

Publication date

2008-11-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31971783&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE414088(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2005-01-28 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2008-11-15 Application granted granted Critical

2008-11-15 Publication of ATE414088T1 publication Critical patent/ATE414088T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Psychology (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Urology & Nephrology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

AT05702040T 2004-01-30 2005-01-28 Polymorphe formen eines gabaa-agonisten ATE414088T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0402118.4A GB0402118D0 (en)	2004-01-30	2004-01-30	Polymorphic forms of a GABAA agonist

Publications (1)

Publication Number	Publication Date
ATE414088T1 true ATE414088T1 (de)	2008-11-15

Family

ID=31971783

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05702040T ATE414088T1 (de)	2004-01-30	2005-01-28	Polymorphe formen eines gabaa-agonisten

Country Status (35)

Country	Link
US (2)	US7262300B2 (de)
EP (2)	EP1713813B1 (de)
JP (1)	JP4917440B2 (de)
KR (1)	KR101210361B1 (de)
CN (1)	CN1914212B (de)
AR (1)	AR047511A1 (de)
AT (1)	ATE414088T1 (de)
AU (1)	AU2005209473B2 (de)
BR (1)	BRPI0506858A (de)
CA (1)	CA2554536C (de)
CO (1)	CO5700743A2 (de)
CY (1)	CY1108647T1 (de)
DE (1)	DE602005010975D1 (de)
DK (1)	DK1713813T3 (de)
DO (1)	DOP2005000013A (de)
EA (1)	EA009413B1 (de)
EC (1)	ECSP066735A (de)
ES (1)	ES2314613T3 (de)
GB (2)	GB0402118D0 (de)
HK (1)	HK1096547A1 (de)
HR (1)	HRP20080614T3 (de)
IL (1)	IL176863A0 (de)
MA (1)	MA28364A1 (de)
MX (1)	MXPA06008595A (de)
MY (1)	MY139525A (de)
NO (1)	NO20063843L (de)
NZ (1)	NZ548191A (de)
PE (1)	PE20050769A1 (de)
PL (1)	PL1713813T3 (de)
PT (1)	PT1713813E (de)
SI (1)	SI1713813T1 (de)
TW (1)	TWI345972B (de)
UA (1)	UA87487C2 (de)
WO (1)	WO2005073237A2 (de)
ZA (1)	ZA200605307B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0402118D0 (en)	2004-01-30	2004-03-03	Merck Sharp & Dohme	Polymorphic forms of a GABAA agonist
US20060063802A1 (en)	2004-03-29	2006-03-23	Matthieu Guitton	Methods for the treatment of tinnitus induced by cochlear excitotoxicity
US9072662B2 (en)	2004-03-29	2015-07-07	Auris Medical Ag	Methods for the treatment of tinnitus induced by cochlear excitotoxicity
US8268866B2 (en)	2004-03-29	2012-09-18	Matthieu Guitton	Methods for the treatment of tinnitus induced by cochlear excitotoxicity
DE102005004343A1 (de) *	2005-01-25	2006-08-10	Eberhard-Karls-Universität Tübingen Universitätsklinikum	Behandlung von Phantomphänomenen
WO2006083682A2 (en) *	2005-01-28	2006-08-10	H.Lundbeck A/S	Polymorphic forms of a gabaa agonist
JP2009509982A (ja)	2005-09-28	2009-03-12	アウリスメディカルアクチエンゲゼルシャフト	内耳疾患を治療するための医薬品組成物
CN102093387B (zh) *	2009-12-10	2012-07-25	天津泰普医药知识产权流转储备中心有限公司	4,5,6,7-四氢异噁唑并[5,4-c]吡啶-3-醇一水合物的晶型化合物
ES2862673T3 (es)	2011-12-12	2021-10-07	Zilentin AG	Tratamiento del tinnitus mediante la modulación del cotransportador de cloruro NKCC1 en el sistema auditivo
EP3324961A4 (de) *	2015-07-17	2019-03-13	Ovid Therapeutics, Inc.	Verfahren zur behandlung von entwicklungsstörungen mit gaboxadol
AU2017311412B2 (en)	2016-08-11	2023-05-18	Ovid Therapeutics Inc.	Methods and compositions for treatment of epileptic disorders
KR20190086709A (ko) *	2016-11-22	2019-07-23	오비드 테라퓨틱스 인크.	가복사돌로 주의력 결핍/과잉행동 장애를 치료하는 방법들
US10071083B2 (en)	2017-02-03	2018-09-11	Ovid Therapeutics Inc	Use of gaboxadol in the treatment of tinnitus
WO2019028234A1 (en)	2017-08-04	2019-02-07	Ovid Therapeutics Inc.	USE OF GABOXADOL IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS
KR20210062662A (ko)	2018-09-20	2021-05-31	오비드 테라퓨틱스 인크.	투렛 증후군, 틱들 및 말더듬의 치료를 위한 가복사돌의 사용
WO2020106927A1 (en)	2018-11-21	2020-05-28	Certego Therapeutics	Gaboxadol for reducing risk of suicide and rapid relief of depression
EP3880201A4 (de)	2018-12-17	2022-07-27	Ovid Therapeutics Inc.	Verwendung von gaboxadol zur behandlung von nicht-24-stündiger schlaf-wach-störung
US11364228B2 (en)	2019-12-18	2022-06-21	Ovid Therapeutics Inc.	Gaboxadol for therapeutic treatment of 1p36 deletion syndrome
IL298334A (en)	2020-05-20	2023-01-01	Certego Therapeutics Inc	A canceled gaboxadol ring and its use for the treatment of psychiatric disorders

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK270278A (da)	1977-06-20	1978-12-21	Krogsgaard Larsen P	Cycliske aminosyrer
US4315934A (en)	1979-09-24	1982-02-16	Sandoz Ltd.	Organic compounds
US4362731A (en)	1980-09-01	1982-12-07	Sandoz Ltd.	Myotonolytic use of 4,5,6,7-tetrahydroisoxazolo [5,4-c] pyridin-3-ol and derivatives thereof
US4352731A (en) *	1980-11-03	1982-10-05	Occidental Research Corporation	Apparatus for selective wetting of particles
DE19525598C2 (de)	1995-07-13	1997-09-25	Max Planck Gesellschaft	Schlafmittel
UA52661C2 (uk) *	1996-06-14	2003-01-15	Ново Нордіск А/С	Безводна кристалічна форма гідрохлориду r(-)-n-(4,4-ди(3-метилтієн-2-іл)бут-3-еніл) ніпекотинової кислоти
CA2385749A1 (en)	1999-09-28	2001-04-05	H. Lundbeck A/S	Melt granulated composition and modified release dosage form prepared from said composition
AR031473A1 (es)	2000-11-20	2003-09-24	Lundbeck & Co As H	Intensificadores de gaba en el tratamiento de enfermedades relacionadas con una reducida actividad neuroesteroide
EP1399138B1 (de)	2001-05-18	2006-02-08	Lonza Ag	Verfahren zur herstellung fester formulierungen von natrium-3-hydroxy-3-methylbutyrat
AR033896A1 (es)	2001-05-21	2004-01-07	Lundbeck & Co As H	Preparaciones granuladas de gaboxadol.
WO2004022550A1 (en) *	2002-09-03	2004-03-18	Naturon Limited	Compound for treatment of anxiety and methods of preparation and use thereof
US20050234093A1 (en) *	2003-06-25	2005-10-20	H. Lundbeck A/S	Treatment of depression and other affective disorders
BRPI0410857A (pt) *	2003-06-25	2006-07-04	Lundbeck & Co As H	método para o tratamento de depressão, uso de gaboxadol, e, composição farmacêutica
AR045540A1 (es) *	2003-09-05	2005-11-02	Lundbeck & Co As H	Metodo de elaboracion de 4,5,6,7 tetrahidroisoxazol [5,4-c] piridin-3-ol (thip)
EP1663218A1 (de)	2003-09-10	2006-06-07	MERCK SHARP & DOHME LTD.	Verwendung von gabaa-rezeptor-agonisten zur behandlung von hör-, vestibular- und aufmerksamkeitsstörungen, intentionstremor und ruhelosen beinen
TW200528098A (en)	2003-12-18	2005-09-01	Lundbeck & Co As H	Treatment of insomnia in human patients
GB0402118D0 (en)	2004-01-30	2004-03-03	Merck Sharp & Dohme	Polymorphic forms of a GABAA agonist
CA2572302A1 (en)	2004-06-29	2006-05-26	H. Lundbeck A/S	Treatment of neuropathic pain, fibromyalgia or rheumatoid arthritis
GB0417558D0 (en)	2004-08-06	2004-09-08	Merck Sharp & Dohme	Novel combination therapy
WO2006083682A2 (en)	2005-01-28	2006-08-10	H.Lundbeck A/S	Polymorphic forms of a gabaa agonist
WO2006102093A1 (en)	2005-03-18	2006-09-28	Transform Pharmaceuticals, Inc.	Gaboxadol forms, compositions thereof, and related methods
US20080262029A1 (en)	2005-04-29	2008-10-23	H. Lundbeck A/S	Acid and Base Salt Forms of Gaboxadol

2004
- 2004-01-30 GB GBGB0402118.4A patent/GB0402118D0/en not_active Ceased
2005
- 2005-01-20 AR ARP050100210A patent/AR047511A1/es not_active Application Discontinuation
- 2005-01-21 TW TW094101857A patent/TWI345972B/zh not_active IP Right Cessation
- 2005-01-24 MY MYPI20050253A patent/MY139525A/en unknown
- 2005-01-27 PE PE2005000102A patent/PE20050769A1/es not_active Application Discontinuation
- 2005-01-28 DK DK05702040T patent/DK1713813T3/da active
- 2005-01-28 PT PT05702040T patent/PT1713813E/pt unknown
- 2005-01-28 GB GB0501847A patent/GB2410434A/en not_active Withdrawn
- 2005-01-28 ES ES05702040T patent/ES2314613T3/es active Active
- 2005-01-28 US US11/045,768 patent/US7262300B2/en active Active
- 2005-01-28 DO DO2005000013A patent/DOP2005000013A/es unknown
- 2005-01-28 EA EA200601404A patent/EA009413B1/ru not_active IP Right Cessation
- 2005-01-28 WO PCT/GB2005/000288 patent/WO2005073237A2/en active Search and Examination
- 2005-01-28 EP EP05702040A patent/EP1713813B1/de active Active
- 2005-01-28 DE DE602005010975T patent/DE602005010975D1/de active Active
- 2005-01-28 NZ NZ548191A patent/NZ548191A/en not_active IP Right Cessation
- 2005-01-28 AU AU2005209473A patent/AU2005209473B2/en not_active Ceased
- 2005-01-28 CA CA2554536A patent/CA2554536C/en not_active Expired - Fee Related
- 2005-01-28 PL PL05702040T patent/PL1713813T3/pl unknown
- 2005-01-28 MX MXPA06008595A patent/MXPA06008595A/es active IP Right Grant
- 2005-01-28 AT AT05702040T patent/ATE414088T1/de active
- 2005-01-28 EP EP08019457A patent/EP2042505A1/de not_active Withdrawn
- 2005-01-28 UA UAA200609410A patent/UA87487C2/ru unknown
- 2005-01-28 SI SI200530521T patent/SI1713813T1/sl unknown
- 2005-01-28 JP JP2006550301A patent/JP4917440B2/ja active Active
- 2005-01-28 BR BRPI0506858-4A patent/BRPI0506858A/pt not_active IP Right Cessation
- 2005-01-28 CN CN2005800031615A patent/CN1914212B/zh active Active
2006
- 2006-06-27 ZA ZA200605307A patent/ZA200605307B/en unknown
- 2006-07-13 IL IL176863A patent/IL176863A0/en unknown
- 2006-07-26 CO CO06073254A patent/CO5700743A2/es not_active Application Discontinuation
- 2006-07-28 EC EC2006006735A patent/ECSP066735A/es unknown
- 2006-07-28 KR KR1020067015417A patent/KR101210361B1/ko not_active IP Right Cessation
- 2006-08-22 MA MA29278A patent/MA28364A1/fr unknown
- 2006-08-29 NO NO20063843A patent/NO20063843L/no not_active Application Discontinuation
2007
- 2007-02-23 HK HK07102068A patent/HK1096547A1/xx unknown
- 2007-07-13 US US11/827,570 patent/US8236958B2/en active Active
2008
- 2008-11-26 HR HR20080614T patent/HRP20080614T3/xx unknown
- 2008-12-10 CY CY20081101439T patent/CY1108647T1/el unknown

Also Published As

Publication number	Publication date
PE20050769A1 (es)	2005-10-04
WO2005073237A2 (en)	2005-08-11
GB0501847D0 (en)	2005-03-09
ES2314613T3 (es)	2009-03-16
NZ548191A (en)	2010-04-30
HK1096547A1 (en)	2007-06-01
IL176863A0 (en)	2006-10-31
TWI345972B (en)	2011-08-01
CO5700743A2 (es)	2006-11-30
DOP2005000013A (es)	2005-08-15
US8236958B2 (en)	2012-08-07
CA2554536A1 (en)	2005-08-11
JP4917440B2 (ja)	2012-04-18
DE602005010975D1 (de)	2008-12-24
KR20070007070A (ko)	2007-01-12
ZA200605307B (en)	2007-11-28
KR101210361B1 (ko)	2012-12-10
MA28364A1 (fr)	2006-12-01
CA2554536C (en)	2012-09-18
EP2042505A1 (de)	2009-04-01
PT1713813E (pt)	2008-12-26
MXPA06008595A (es)	2006-08-28
GB0402118D0 (en)	2004-03-03
UA87487C2 (ru)	2009-07-27
EA009413B1 (ru)	2007-12-28
WO2005073237A3 (en)	2005-10-20
GB2410434A (en)	2005-08-03
AR047511A1 (es)	2006-01-25
ECSP066735A (es)	2006-10-31
TW200534856A (en)	2005-11-01
SI1713813T1 (sl)	2009-02-28
AU2005209473A1 (en)	2005-08-11
EP1713813A2 (de)	2006-10-25
JP2007519697A (ja)	2007-07-19
CN1914212B (zh)	2010-10-06
NO20063843L (no)	2006-08-29
EP1713813B1 (de)	2008-11-12
PL1713813T3 (pl)	2009-04-30
US20050171142A1 (en)	2005-08-04
DK1713813T3 (da)	2009-02-16
US20070259912A1 (en)	2007-11-08
CN1914212A (zh)	2007-02-14
HRP20080614T3 (en)	2009-01-31
EA200601404A1 (ru)	2006-12-29
AU2005209473B2 (en)	2010-03-04
US7262300B2 (en)	2007-08-28
BRPI0506858A (pt)	2007-05-29
MY139525A (en)	2009-10-30
CY1108647T1 (el)	2014-04-09

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2009-05-15

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