ATE404588T1 - Verfahren zur herstellung von chondroitinsulfaten aus k4-polysaccharid und so hergestellte produkte - Google Patents
Verfahren zur herstellung von chondroitinsulfaten aus k4-polysaccharid und so hergestellte produkteInfo
- Publication number
- ATE404588T1 ATE404588T1 AT02023351T AT02023351T ATE404588T1 AT E404588 T1 ATE404588 T1 AT E404588T1 AT 02023351 T AT02023351 T AT 02023351T AT 02023351 T AT02023351 T AT 02023351T AT E404588 T1 ATE404588 T1 AT E404588T1
- Authority
- AT
- Austria
- Prior art keywords
- polysaccharide
- products produced
- producing chondroitin
- chondroitin sulphates
- sulphates
- Prior art date
Links
- 150000004676 glycans Chemical class 0.000 title abstract 2
- 229920001282 polysaccharide Polymers 0.000 title abstract 2
- 239000005017 polysaccharide Substances 0.000 title abstract 2
- -1 CHONDROITIN SULPHATES Chemical class 0.000 title 1
- 229920002567 Chondroitin Polymers 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 229920001287 Chondroitin sulfate Polymers 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 229940107200 chondroitin sulfates Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000019635 sulfation Effects 0.000 abstract 1
- 238000005670 sulfation reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2001MI002200A ITMI20012200A1 (it) | 2001-10-22 | 2001-10-22 | Processo per la preparazione di condroitin solfati dal polisaccaride k4 e prodotti ottenuti |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE404588T1 true ATE404588T1 (de) | 2008-08-15 |
Family
ID=11448534
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02023351T ATE404588T1 (de) | 2001-10-22 | 2002-10-18 | Verfahren zur herstellung von chondroitinsulfaten aus k4-polysaccharid und so hergestellte produkte |
Country Status (7)
Country | Link |
---|---|
US (1) | US6777398B2 (de) |
EP (1) | EP1304338B1 (de) |
AT (1) | ATE404588T1 (de) |
CA (1) | CA2408681A1 (de) |
DE (1) | DE60228184D1 (de) |
ES (1) | ES2312519T3 (de) |
IT (1) | ITMI20012200A1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030104601A1 (en) * | 1999-04-01 | 2003-06-05 | Deangelis Paul L. | Chondroitin synthase gene and methods of making and using same |
US20060188966A1 (en) * | 1998-04-02 | 2006-08-24 | Deangelis Paul L | Natural, chimeric and hybrid glycosaminoglycan polymers and methods of making and using same |
US7223571B2 (en) | 1998-04-02 | 2007-05-29 | The Board Of Regents Of The Universtiy Of Oklahoma | Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same |
US20080108110A1 (en) * | 1998-04-02 | 2008-05-08 | Deangelis Paul L | Targeted glycosaminoglycan polymers by polymer grafting and methods of making and using same |
US7642071B2 (en) | 1999-04-01 | 2010-01-05 | The Board Of Regents Of The University Of Oklahoma | Methods of expressing gram-negative glycosaminoglycan synthase genes in gram-positive hosts |
ITMI20032498A1 (it) | 2003-12-17 | 2005-06-18 | Pasqua Anna Oreste | Polisaccaridi antitrombotici a basso peso molecolare e |
ITMI20010397A1 (it) * | 2001-02-27 | 2002-08-27 | Giorgio Zoppetti | Derivati altamente n,o-solfatati del polisaccaride k5 e loro preparazione |
US8513407B2 (en) * | 2002-06-18 | 2013-08-20 | Glycores 2000 S.R.L. | Process for the preparation of N-acyl-(epi)K5-amine-O-sulfate-derivatives and products thus obtained |
PL375087A1 (en) * | 2002-06-18 | 2005-11-14 | Glycores 2000 S.R.L. | Low molecular weight oversulfated polysaccharide |
EP2296670B1 (de) | 2008-05-13 | 2013-02-27 | Apharm S.r.l. | Orale anwendung von glycosaminoglycan und zusammensetzungen |
WO2009149155A1 (en) | 2008-06-04 | 2009-12-10 | Amano Enzyme Usa., Ltd. | Microbial-derived chondroitin sulfate |
IT1394311B1 (it) * | 2009-05-25 | 2012-06-06 | Altergon Sa | Produzione biotecnologica di condroitina |
ITMI20110505A1 (it) | 2011-03-29 | 2012-09-30 | Altergon Sa | Processo per la preparazione di condroitine solfatate in posizione 3 sull'acido glucuronico |
DK2707396T3 (en) * | 2011-05-12 | 2019-01-28 | Gnosis Spa | Biotechnological sulfated chondroitin sulfate at position 4 or 6 on the same polysaccharide chain and process for its preparation |
ITMI20120136A1 (it) * | 2012-02-02 | 2013-08-03 | Gnosis Spa | Condroitin solfato biotecnologico a basso peso molecolare solfatato in posizione 4 o 6 sulla stessa catena polisaccaridica dotato di attivita' antiinfiammatoria e antiartritica e procedimento per la sua preparazione |
ITMI20110829A1 (it) | 2011-05-12 | 2012-11-13 | Gnosis Spa | Condroitin solfato biotecnologico solfatato in posizione 4 o 6 sulla stessa catena polisaccaridica e procedimento per la sua preparazione |
BR112013029765B1 (pt) * | 2011-05-20 | 2021-02-17 | Gnosis S.P.A. | sulfato de condroitina similar ao de tubarão e processo para o preparo do mesmo |
US8664196B2 (en) | 2011-05-20 | 2014-03-04 | Gnosis S.P.A. | Shark-like chondroitin sulphate and process for the preparation thereof |
CN102618597A (zh) * | 2012-04-06 | 2012-08-01 | 江南大学 | 大肠杆菌工程菌及其生产软骨素的方法 |
ITMI20120880A1 (it) * | 2012-05-22 | 2013-11-23 | Gnosis Spa | Condroitin 6-solfato biotecnologico a basso peso molecolare dotato di attivita' antiinfiammatoria e antiartritica e suo uso nel trattamento e nella prevenzione dell'osteoartrite |
ITMI20120896A1 (it) | 2012-05-23 | 2013-11-24 | Bongulielmi Reto | Condroitina per uso in medicina |
ITMI20121316A1 (it) | 2012-07-27 | 2014-01-28 | Altergon Sa | Complessi di condroitina ad assorbimento transcutaneo |
ITMI20130117A1 (it) * | 2013-01-25 | 2014-07-26 | Gnosis Spa | Composizioni comprendenti condroitin solfato, enzimi proteolitici e composti sulfidrilati capaci di migliorare la biodisponibilita' del condroitin solfato |
CN104163877B (zh) * | 2014-08-26 | 2016-05-18 | 淮安麦德森制药有限公司 | 硫酸软骨素的制备方法 |
EP3240550B1 (de) | 2015-10-01 | 2019-04-10 | Apharm S.r.l. | Kombination aus glucosaminoglykanen und einem antazidum und zusammensetzungen davon |
CN108484795B (zh) * | 2018-04-28 | 2021-02-09 | 山东第一医科大学第二附属医院 | 硫酸软骨素锂及其制备方法和应用 |
IT202000013633A1 (it) * | 2020-06-08 | 2021-12-08 | Vivatis Pharma Gmbh | Processo di estrazione di una condroitina solfato da un fungo, una condroitina solfato di origine vegetale e suo uso |
CN115353574B (zh) * | 2022-09-06 | 2023-06-13 | 福建省深蓝生物科技有限公司 | 高硫酸化度的硫酸软骨素cs-e及其提取方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3895107A (en) * | 1970-04-15 | 1975-07-15 | Morrison L M | CSA and CSC in man and mammals to inhibit atherosclerosis and the recurrence of cardiovascular incidents in atherosclerotic mammals |
US4302577A (en) * | 1979-10-05 | 1981-11-24 | Biomed Research Inc. | Process for preparing CSA or CSC |
IT1289613B1 (it) * | 1997-02-07 | 1998-10-15 | Inalco Spa | Polisaccaridi batterici o-solfatati |
ITMI991465A1 (it) | 1999-07-02 | 2001-01-02 | Inalco Spa | Processo per la preparazione dei polisaccaridi k4 e k5 da escherichiacoli |
-
2001
- 2001-10-22 IT IT2001MI002200A patent/ITMI20012200A1/it unknown
-
2002
- 2002-10-17 CA CA002408681A patent/CA2408681A1/en not_active Abandoned
- 2002-10-18 ES ES02023351T patent/ES2312519T3/es not_active Expired - Lifetime
- 2002-10-18 DE DE60228184T patent/DE60228184D1/de not_active Expired - Lifetime
- 2002-10-18 EP EP02023351A patent/EP1304338B1/de not_active Expired - Lifetime
- 2002-10-18 AT AT02023351T patent/ATE404588T1/de active
- 2002-10-21 US US10/274,706 patent/US6777398B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2408681A1 (en) | 2003-04-22 |
EP1304338B1 (de) | 2008-08-13 |
ITMI20012200A1 (it) | 2003-04-22 |
ES2312519T3 (es) | 2009-03-01 |
US6777398B2 (en) | 2004-08-17 |
DE60228184D1 (de) | 2008-09-25 |
US20030100534A1 (en) | 2003-05-29 |
EP1304338A1 (de) | 2003-04-23 |
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