ATE465990T1 - Arylalkylcarbamatderivate, verfahren zur ihrer herstellung und deren therapeutischen anwendungen - Google Patents

Arylalkylcarbamatderivate, verfahren zur ihrer herstellung und deren therapeutischen anwendungen

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Publication number
ATE465990T1
ATE465990T1 AT04704251T AT04704251T ATE465990T1 AT E465990 T1 ATE465990 T1 AT E465990T1 AT 04704251 T AT04704251 T AT 04704251T AT 04704251 T AT04704251 T AT 04704251T AT E465990 T1 ATE465990 T1 AT E465990T1
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Austria
Prior art keywords
arylalkylcarbamat
derivatives
production
therapeutic applications
therapeutic
Prior art date
Application number
AT04704251T
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English (en)
Inventor
Ahmed Abouabdellah
Garcia Antonio Almario
Christian Hoornaert
Antoine Ravet
Original Assignee
Sanofi Aventis
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Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
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Publication of ATE465990T1 publication Critical patent/ATE465990T1/de

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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
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    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/12—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
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    • A—HUMAN NECESSITIES
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C269/00—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C269/06—Preparation of derivatives of carbamic acid, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups by reactions not involving the formation of carbamate groups
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    • C07C271/14—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by halogen atoms or by nitro or nitroso groups
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    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
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    • C07C271/16—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
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    • C07C271/18—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by doubly-bound oxygen atoms
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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
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    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
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AT04704251T 2003-01-23 2004-01-22 Arylalkylcarbamatderivate, verfahren zur ihrer herstellung und deren therapeutischen anwendungen ATE465990T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0300704A FR2850377B1 (fr) 2003-01-23 2003-01-23 Derives d'arylalkylcarbamates, leur preparation et leur application en therapeutique
PCT/FR2004/000139 WO2004067498A2 (fr) 2003-01-23 2004-01-22 Derives d’ arylalkylcarbamates, leur preparation et leur application en therapeutique

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ATE465990T1 true ATE465990T1 (de) 2010-05-15

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US (1) US7632850B2 (de)
EP (1) EP1590321B1 (de)
JP (1) JP4617292B2 (de)
KR (1) KR20050104352A (de)
CN (2) CN100506788C (de)
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FR2866884B1 (fr) * 2004-02-26 2007-08-31 Sanofi Synthelabo Derives d'aryl-et d'heteroaryl-piperidinecarboxylates, leur preparation et leur application en therapeutique
FR2866886B1 (fr) 2004-02-26 2007-08-31 Sanofi Synthelabo Derives d'aryl-et d'heteroaryl-akylcarbamates, leur preparation et leur application en therapeutique
FR2866885B1 (fr) * 2004-02-26 2007-08-31 Sanofi Synthelabo Derives de piperidinylalkylcarbamates, leur prepation et leur application en therapeutique
DE102004039326A1 (de) * 2004-08-12 2006-02-16 Abbott Gmbh & Co. Kg Neue medizinische Verwendungen und Verfahren
CA2596393C (en) * 2004-12-30 2014-09-23 Janssen Pharmaceutica N.V. 4-(benzyl)-piperazine-1-carboxylic acid phenylamide derivatives and related compounds as modulators of fatty acid amide hydrolase for the treatment of anxiety, pain and other conditions
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PT1590321E (pt) 2010-07-06
FR2850377B1 (fr) 2009-02-20
BRPI0406901A (pt) 2005-12-13
EP1590321B1 (de) 2010-04-28
TNSN05172A1 (fr) 2007-05-14
CN101058564A (zh) 2007-10-24
NO20053593L (no) 2005-10-21
NO20053593D0 (no) 2005-07-22
IS7916A (is) 2005-06-27
EA200500979A1 (ru) 2006-02-24
CN1741990A (zh) 2006-03-01
MXPA05007848A (es) 2005-10-18
IL169444A0 (en) 2007-07-04
SI1590321T1 (sl) 2010-08-31
DE602004026826D1 (de) 2010-06-10
CA2511941A1 (en) 2004-08-12
DK1590321T3 (da) 2010-08-09
JP2006517218A (ja) 2006-07-20
EA008801B1 (ru) 2007-08-31
RS20050562A (en) 2007-12-31
TW200503993A (en) 2005-02-01
JP4617292B2 (ja) 2011-01-19
AU2004207657B2 (en) 2010-09-16
HRP20050631A2 (en) 2005-08-31
AR042746A1 (es) 2005-06-29
ES2344454T3 (es) 2010-08-27
CN101058564B (zh) 2010-05-26
WO2004067498A3 (fr) 2004-11-04
US20060014830A1 (en) 2006-01-19
WO2004067498A2 (fr) 2004-08-12
CN100506788C (zh) 2009-07-01
MA27609A1 (fr) 2005-11-01
UA86013C2 (ru) 2009-03-25
TWI330628B (en) 2010-09-21
EP1590321A2 (de) 2005-11-02
KR20050104352A (ko) 2005-11-02
IL169444A (en) 2011-06-30
ZA200505351B (en) 2006-09-27
NZ541148A (en) 2009-01-31
HK1085193A1 (en) 2006-08-18
FR2850377A1 (fr) 2004-07-30
CY1110216T1 (el) 2015-01-14
MEP21308A (en) 2010-06-10
AU2004207657A1 (en) 2004-08-12
US7632850B2 (en) 2009-12-15
PL378022A1 (pl) 2006-02-20

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