ATE39920T1 - Cyclopentylether, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung. - Google Patents
Cyclopentylether, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung.Info
- Publication number
- ATE39920T1 ATE39920T1 AT85302830T AT85302830T ATE39920T1 AT E39920 T1 ATE39920 T1 AT E39920T1 AT 85302830 T AT85302830 T AT 85302830T AT 85302830 T AT85302830 T AT 85302830T AT E39920 T1 ATE39920 T1 AT E39920T1
- Authority
- AT
- Austria
- Prior art keywords
- sub
- production
- pharmaceutical application
- cyclopentyl ether
- sup
- Prior art date
Links
- BOTLEXFFFSMRLQ-UHFFFAOYSA-N cyclopentyloxycyclopentane Chemical compound C1CCCC1OC1CCCC1 BOTLEXFFFSMRLQ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- -1 3-phenoxy-2-hydroxypropyl Chemical group 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 230000027119 gastric acid secretion Effects 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/753—Unsaturated compounds containing a keto groups being part of a ring containing ether groups, groups, groups, or groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/58—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in three-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/20—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms
- C07C47/277—Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/613—Unsaturated compounds containing a keto groups being part of a ring polycyclic
- C07C49/617—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system
- C07C49/623—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system having two rings
- C07C49/627—Unsaturated compounds containing a keto groups being part of a ring polycyclic a keto group being part of a condensed ring system having two rings the condensed ring system containing seven carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848410396A GB8410396D0 (en) | 1984-04-24 | 1984-04-24 | Carbocyclic compounds |
EP85302830A EP0160495B1 (de) | 1984-04-24 | 1985-04-23 | Cyclopentylether, Verfahren zu ihrer Herstellung und ihre pharmazeutische Anwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE39920T1 true ATE39920T1 (de) | 1989-01-15 |
Family
ID=10559964
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT85302830T ATE39920T1 (de) | 1984-04-24 | 1985-04-23 | Cyclopentylether, verfahren zu ihrer herstellung und ihre pharmazeutische anwendung. |
Country Status (10)
Country | Link |
---|---|
US (1) | US4837363A (de) |
EP (1) | EP0160495B1 (de) |
JP (1) | JPS60252459A (de) |
AT (1) | ATE39920T1 (de) |
AU (1) | AU588526B2 (de) |
CA (1) | CA1248527A (de) |
DE (1) | DE3567453D1 (de) |
DK (1) | DK180985A (de) |
GB (1) | GB8410396D0 (de) |
ZA (1) | ZA853016B (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8510277D0 (en) * | 1985-04-23 | 1985-05-30 | Glaxo Group Ltd | Carbocyclic compounds |
US4824993A (en) * | 1984-04-23 | 1989-04-25 | Glaxo Group Limited | Cyclopentyl ethers and their preparation and pharmaceutical formulation |
GB8625321D0 (en) * | 1986-10-22 | 1986-11-26 | Glaxo Group Ltd | Chemical compounds |
GB8625322D0 (en) * | 1986-10-22 | 1986-11-26 | Glaxo Group Ltd | Chemical compounds |
GB8625326D0 (en) * | 1986-10-22 | 1986-11-26 | Glaxo Group Ltd | Medicaments |
US5254708A (en) * | 1987-06-16 | 1993-10-19 | Nissan Chemical Industries, Ltd. | Substituted cyclic ketones, substituted cyclic enones, and process for producing the same |
JP2696933B2 (ja) * | 1987-06-16 | 1998-01-14 | 日産化学工業株式会社 | 置換環状ケトン及び置換環状エノン並びにそれらの製造法 |
US5227505A (en) * | 1987-06-16 | 1993-07-13 | Nissan Chemical Industries, Ltd. | Substituted cyclic ketones, substituted cyclic enones, and process for producing the same |
US5231208A (en) * | 1987-06-16 | 1993-07-27 | Nissan Chemical Industries, Ltd. | Substituted cyclic ketones, substituted cyclic enones, and process for producing the same |
AU1709699A (en) * | 1997-12-22 | 1999-07-12 | Alcon Laboratories, Inc. | 13-oxa prostaglandins for the treatment of glaucoma and ocular hypertension |
JP5427029B2 (ja) | 2006-09-06 | 2014-02-26 | スキャンポ・アーゲー | 消化管の重炭酸分泌を促進するための方法および組成物 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5159841A (ja) * | 1974-09-20 | 1976-05-25 | Ono Pharmaceutical Co | Purosutaguranjinruijikagobutsuno seizoho |
US4271314A (en) * | 1979-11-28 | 1981-06-02 | G. D. Searle & Co. | 4,5-Unsaturated prostanoic acid derivatives |
GB2082176B (en) * | 1980-08-12 | 1984-07-11 | Sanofi Sa | Heteroprostaglandin derivatives and processes for preparing them |
HU184950B (en) * | 1981-04-14 | 1984-11-28 | Chinoin Gyogyszer Es Vegyeszet | Process for preparing new 13-oxa-prostacyclin derivatives |
JPS595154A (ja) * | 1982-06-30 | 1984-01-12 | Ono Pharmaceut Co Ltd | プロスタグランジンd類似化合物 |
US4499296A (en) * | 1983-11-14 | 1985-02-12 | G. D. Searle & Co. | Omega cycloalkyl prostaglandins |
-
1984
- 1984-04-24 GB GB848410396A patent/GB8410396D0/en active Pending
-
1985
- 1985-04-23 AU AU41631/85A patent/AU588526B2/en not_active Ceased
- 1985-04-23 AT AT85302830T patent/ATE39920T1/de not_active IP Right Cessation
- 1985-04-23 EP EP85302830A patent/EP0160495B1/de not_active Expired
- 1985-04-23 ZA ZA853016A patent/ZA853016B/xx unknown
- 1985-04-23 DE DE8585302830T patent/DE3567453D1/de not_active Expired
- 1985-04-23 DK DK180985A patent/DK180985A/da not_active Application Discontinuation
- 1985-04-23 US US06/726,332 patent/US4837363A/en not_active Expired - Lifetime
- 1985-04-23 JP JP60085570A patent/JPS60252459A/ja active Pending
- 1985-04-24 CA CA000479981A patent/CA1248527A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0160495A3 (en) | 1986-08-27 |
AU588526B2 (en) | 1989-09-21 |
GB8410396D0 (en) | 1984-05-31 |
AU4163185A (en) | 1985-10-31 |
JPS60252459A (ja) | 1985-12-13 |
CA1248527A (en) | 1989-01-10 |
US4837363A (en) | 1989-06-06 |
DK180985A (da) | 1985-10-25 |
EP0160495A2 (de) | 1985-11-06 |
EP0160495B1 (de) | 1989-01-11 |
DE3567453D1 (en) | 1989-02-16 |
DK180985D0 (da) | 1985-04-23 |
ZA853016B (en) | 1985-12-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |