ATE396708T1 - Zusammensetzungen für die chemoembolotherapie solider tumoren - Google Patents
Zusammensetzungen für die chemoembolotherapie solider tumorenInfo
- Publication number
- ATE396708T1 ATE396708T1 AT04710431T AT04710431T ATE396708T1 AT E396708 T1 ATE396708 T1 AT E396708T1 AT 04710431 T AT04710431 T AT 04710431T AT 04710431 T AT04710431 T AT 04710431T AT E396708 T1 ATE396708 T1 AT E396708T1
- Authority
- AT
- Austria
- Prior art keywords
- chemoembolotherapy
- compositions
- solid tumors
- polymer
- water
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/06—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0015—Medicaments; Biocides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2/00—Processes of polymerisation
- C08F2/12—Polymerisation in non-solvents
- C08F2/14—Organic medium
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F290/00—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups
- C08F290/08—Macromolecular compounds obtained by polymerising monomers on to polymers modified by introduction of aliphatic unsaturated end or side groups on to polymers modified by introduction of unsaturated side groups
- C08F290/12—Polymers provided for in subclasses C08C or C08F
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/48—Isomerisation; Cyclisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/23—Carbohydrates
- A61L2300/232—Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/06—Flowable or injectable implant compositions
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F2810/00—Chemical modification of a polymer
- C08F2810/30—Chemical modification of a polymer leading to the formation or introduction of aliphatic or alicyclic unsaturated groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Surgery (AREA)
- Materials Engineering (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03250868 | 2003-02-12 | ||
GB0305322A GB0305322D0 (en) | 2003-03-07 | 2003-03-07 | Chemoembolisation |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE396708T1 true ATE396708T1 (de) | 2008-06-15 |
Family
ID=32870779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04710431T ATE396708T1 (de) | 2003-02-12 | 2004-02-12 | Zusammensetzungen für die chemoembolotherapie solider tumoren |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP1592405B1 (de) |
JP (2) | JP4895802B2 (de) |
KR (1) | KR101157260B1 (de) |
CN (4) | CN102895662B (de) |
AT (1) | ATE396708T1 (de) |
DE (1) | DE602004014101D1 (de) |
ES (1) | ES2308149T3 (de) |
HK (1) | HK1079980B (de) |
WO (1) | WO2004071495A1 (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60130743T2 (de) | 2000-03-24 | 2008-07-17 | Biosphere Medical, Inc., Rockland | Mikrokugeln zur aktiven embolisierung |
WO2005087193A2 (en) * | 2004-03-11 | 2005-09-22 | Biocompatibles Uk Limited | Chemoembolisation involving an anthracycline compound |
EP1796644B1 (de) * | 2004-09-07 | 2011-04-13 | Biocompatibles UK Limited | Arzneimittelabgabe aus embolischen mitteln |
MX2007013914A (es) | 2005-05-09 | 2008-02-22 | Biosphere Medical S A | Composiciones y metodos que usan microesferas y agentes de contraste no ionicos. |
ES2554527T3 (es) * | 2006-01-24 | 2015-12-21 | Biocompatibles Uk Limited | Proceso para rellenar partículas poliméricas con un fármaco |
EP1986707A2 (de) | 2006-01-30 | 2008-11-05 | Surgica Corporation | Komprimierbare intravaskuläre embolisationsteilchen und relevante verfahren und abgabesysteme |
US9107833B2 (en) | 2006-06-22 | 2015-08-18 | Biocompatibles Uk Limited | Rehydratable pharmaceutical product |
EP1985286A1 (de) | 2007-04-24 | 2008-10-29 | Biocompatibles UK Limited | Mikrokügelchen zur Behandlung von Gehirntumoren |
WO2008138758A1 (en) * | 2007-05-11 | 2008-11-20 | Nerviano Medical Sciences S.R.L. | Pharmaceutical composition of an anthracycline |
EP2190409B9 (de) * | 2007-08-16 | 2019-03-06 | Biocompatibles UK Limited | Verabreichung von arzneimittelkombinationen |
CN105999297A (zh) * | 2008-12-02 | 2016-10-12 | 生物相容英国有限公司 | 胰腺肿瘤治疗 |
GB201101429D0 (en) * | 2011-01-27 | 2011-03-16 | Biocompatibles Uk Ltd | Drug delivery system |
JP5957610B2 (ja) | 2012-08-31 | 2016-07-27 | チュンアン ユニバーシティー インダストリー アカデミック コアポレイション ファウンデイション | 塞栓用のミクロスフェアの製造方法及び薬物含有ナノ輸送体が結合されたミクロスフェアの製造方法 |
JP6420817B2 (ja) | 2013-03-15 | 2018-11-07 | バイオコンパティブルズ ユーケー リミテッド | 結像可能な塞栓性微小球 |
GB2519738A (en) | 2013-09-06 | 2015-05-06 | Biocompatibles Uk Ltd | Radiopaque polymers |
GB2521997A (en) | 2013-09-06 | 2015-07-15 | Biocompatibles Uk Ltd | Radiopaque polymers |
ES2907571T3 (es) * | 2015-03-02 | 2022-04-25 | Accurate Medical Therapeutics Ltd | Prevención de embolización no diana |
GB201515602D0 (en) | 2015-09-03 | 2015-10-21 | Biocompatibles Uk Ltd | Polymers and microspheres |
CN108883189B (zh) | 2016-03-14 | 2022-06-21 | 生物相容性英国公司 | 包含颗粒的乳液 |
US11382990B2 (en) | 2016-11-16 | 2022-07-12 | The Usa, As Represented By The Secretary, Dhhs | Imageable polymers, methods of making and methods of use thereof |
CN110891550B (zh) | 2017-07-13 | 2023-03-07 | 瓦里安医疗***公司 | 栓塞微球 |
WO2019087191A1 (en) | 2017-11-02 | 2019-05-09 | Accurate Medical Therapeutics Ltd. | Embolization catheter with integral filter |
US11702498B2 (en) | 2018-06-29 | 2023-07-18 | Biocompatibles Uk Limited | Radiopaque polymers |
EP3941437A1 (de) | 2019-03-22 | 2022-01-26 | Biocompatibles UK Limited | Embolische mikrokügelchen und verfahren |
GB201910286D0 (en) | 2019-07-18 | 2019-09-04 | Biocompatibles Uk Ltd | Radiopaque polymers |
IL295498A (en) * | 2020-02-25 | 2022-10-01 | Hepion Pharmaceuticals Inc | Use of cyclosporine analogs for cancer treatment |
CN113797383A (zh) * | 2021-09-28 | 2021-12-17 | 迪格瑞医疗科技(苏州)有限公司 | 一种高弹性、高载药量的栓塞微球及其制备方法 |
US20230201122A1 (en) | 2021-12-23 | 2023-06-29 | Boston Scientific Medical Device Limited | Chemoembolic compositions and methods of treatment using them |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4978713A (en) * | 1987-12-16 | 1990-12-18 | Ciba-Geigy Corporation | Polyvinyl alcohol derivatives containing pendant vinylic monomer reaction product units bound through ether groups and hydrogel contact lenses made therefrom |
JP3041627B2 (ja) * | 1989-04-13 | 2000-05-15 | 武田薬品工業株式会社 | アントラサイクリン系抗生物質の安定組成物 |
JPH06329542A (ja) * | 1993-05-21 | 1994-11-29 | Kibun Food Chemifa Co Ltd | 不溶性アルギン酸塩粒子を含む局所血管止血用組成物および動脈化学塞栓用組成物 |
EP0727984B1 (de) * | 1993-11-18 | 2003-06-25 | Sirtex Medical Limited | Zubereitung mit gesteuerter freisetzung |
WO1999012577A1 (en) * | 1997-09-05 | 1999-03-18 | Nycomed Imaging As | Polymer particles made of polyvinyl alcohol and comprising a contrast agent for chemoembolization |
DE60130544T2 (de) * | 2000-03-13 | 2008-06-26 | Biocure, Inc. | Embolische zusammensetzungen |
US6852816B2 (en) * | 2000-10-06 | 2005-02-08 | Biocompatibles Uk Limited | Zwitterionic polymers |
EP1556090A1 (de) * | 2002-09-25 | 2005-07-27 | Biocompatibles UK Limited | Polymerzusammensetzungen zur verabreichung an tiere |
-
2004
- 2004-02-12 CN CN201210299592.2A patent/CN102895662B/zh not_active Expired - Lifetime
- 2004-02-12 WO PCT/GB2004/000548 patent/WO2004071495A1/en active IP Right Grant
- 2004-02-12 ES ES04710431T patent/ES2308149T3/es not_active Expired - Lifetime
- 2004-02-12 KR KR1020057014847A patent/KR101157260B1/ko active IP Right Grant
- 2004-02-12 AT AT04710431T patent/ATE396708T1/de not_active IP Right Cessation
- 2004-02-12 CN CN201410044028.5A patent/CN103908704B/zh not_active Expired - Lifetime
- 2004-02-12 DE DE602004014101T patent/DE602004014101D1/de not_active Expired - Lifetime
- 2004-02-12 JP JP2006500252A patent/JP4895802B2/ja not_active Expired - Lifetime
- 2004-02-12 EP EP04710431A patent/EP1592405B1/de not_active Expired - Lifetime
- 2004-02-12 CN CN201610844279.0A patent/CN106267325B/zh not_active Expired - Lifetime
- 2004-02-12 CN CN201310320841.6A patent/CN103393605B/zh not_active Expired - Lifetime
-
2005
- 2005-12-30 HK HK05112166.8A patent/HK1079980B/zh not_active IP Right Cessation
-
2011
- 2011-02-21 JP JP2011034961A patent/JP5616251B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP5616251B2 (ja) | 2014-10-29 |
JP4895802B2 (ja) | 2012-03-14 |
JP2006515358A (ja) | 2006-05-25 |
WO2004071495A1 (en) | 2004-08-26 |
CN102895662B (zh) | 2017-09-12 |
ES2308149T3 (es) | 2008-12-01 |
HK1079980A1 (en) | 2006-04-21 |
CN106267325A (zh) | 2017-01-04 |
KR101157260B1 (ko) | 2012-06-15 |
JP2011178784A (ja) | 2011-09-15 |
CN103908704A (zh) | 2014-07-09 |
DE602004014101D1 (de) | 2008-07-10 |
HK1079980B (zh) | 2008-11-14 |
CN103393605A (zh) | 2013-11-20 |
EP1592405B1 (de) | 2008-05-28 |
KR20050103224A (ko) | 2005-10-27 |
CN102895662A (zh) | 2013-01-30 |
CN106267325B (zh) | 2019-09-24 |
CN103393605B (zh) | 2018-05-29 |
CN103908704B (zh) | 2017-09-01 |
EP1592405A1 (de) | 2005-11-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |