ATE388701T1 - Halbfeste formulierung für die orale verabreichung des taxols - Google Patents

Halbfeste formulierung für die orale verabreichung des taxols

Info

Publication number
ATE388701T1
ATE388701T1 AT04741331T AT04741331T ATE388701T1 AT E388701 T1 ATE388701 T1 AT E388701T1 AT 04741331 T AT04741331 T AT 04741331T AT 04741331 T AT04741331 T AT 04741331T AT E388701 T1 ATE388701 T1 AT E388701T1
Authority
AT
Austria
Prior art keywords
taxol
semi
oral administration
solid formulation
formulation
Prior art date
Application number
AT04741331T
Other languages
English (en)
Inventor
Tatiana Borovac
Carole Neves
Maria-Teresa Peracchia
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of ATE388701T1 publication Critical patent/ATE388701T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT04741331T 2003-07-18 2004-07-15 Halbfeste formulierung für die orale verabreichung des taxols ATE388701T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP03291795A EP1498120A1 (de) 2003-07-18 2003-07-18 Halbfeste Formulierung für die orale Verabreichung des Taxols

Publications (1)

Publication Number Publication Date
ATE388701T1 true ATE388701T1 (de) 2008-03-15

Family

ID=33462258

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04741331T ATE388701T1 (de) 2003-07-18 2004-07-15 Halbfeste formulierung für die orale verabreichung des taxols

Country Status (21)

Country Link
US (1) US20050070496A1 (de)
EP (2) EP1498120A1 (de)
JP (1) JP5116306B2 (de)
KR (1) KR101143341B1 (de)
CN (1) CN1826110B (de)
AR (1) AR045996A1 (de)
AT (1) ATE388701T1 (de)
AU (1) AU2004262496B2 (de)
BR (1) BRPI0412759A (de)
CA (1) CA2532667A1 (de)
DE (1) DE602004012413T2 (de)
DK (1) DK1648440T3 (de)
ES (1) ES2303642T3 (de)
HK (1) HK1091743A1 (de)
IL (1) IL173110A (de)
IN (1) IN229997B (de)
MX (1) MX260260B (de)
MY (1) MY137965A (de)
PT (1) PT1648440E (de)
TW (1) TWI342774B (de)
WO (1) WO2005013968A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1498143A1 (de) * 2003-07-18 2005-01-19 Aventis Pharma S.A. Selbstemulgierende und selbstmicroemulgierende Formulierungen zur oralen Verabreichung von Taxoiden
EP2338488A1 (de) * 2006-05-26 2011-06-29 Bayer HealthCare, LLC Arzneikombinationen mit substituierten Diaryl-Harnstoffen zur Krebsbehandlung
FR2922107B1 (fr) * 2007-10-10 2010-02-26 Aventis Pharma Sa Nouvelles compositions a base de taxoides
FR2924024B1 (fr) 2007-11-27 2012-08-17 Centre Nat Rech Scient Nanoparticules d'actifs therapeutiques de faible solubilite aqueuse
FR2931152B1 (fr) * 2008-05-16 2010-07-30 Centre Nat Rech Scient Nouveau systeme de transfert d'acide nucleique
PE20121429A1 (es) 2009-10-29 2012-11-06 Aventis Pharma Sa Nuevo uso antitumoral de cabazitaxel
BR112012028037A2 (pt) 2010-05-03 2016-08-02 Teikoku Pharma Usa Inc formulação de pró-emulsão líquida de taxano não aquosa, métodos para administrar um taxano a um paciente e para fabricar uma formulação de pró-emulsão de taxano, composição de emulsão de taxano, e, kit
JO3685B1 (ar) 2012-10-01 2020-08-27 Teikoku Pharma Usa Inc صيغ التشتيت الجسيمي للتاكسين غير المائي وطرق استخدامها
CN103980232A (zh) * 2014-06-05 2014-08-13 北京诺普德医药科技有限公司 10-乙酰基多西紫杉醇及其用途
KR101542364B1 (ko) * 2014-10-31 2015-08-07 대화제약 주식회사 탁산을 포함하는 경구 투여용 약학 조성물
CN113698369A (zh) * 2021-08-31 2021-11-26 无锡紫杉药业有限公司 一种除去卡巴他赛中特定单杂的方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3406497A1 (de) * 1984-02-23 1985-09-05 Mueller Bernhard Willi Werner Hochdisperse pharmazeutische mehrkomponentensysteme und verfahren zu ihrer herstellung
US5272171A (en) * 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
US5294637A (en) * 1992-07-01 1994-03-15 Bristol-Myers Squibb Company Fluoro taxols
JP3208517B2 (ja) * 1992-07-01 2001-09-17 ブリストル−マイヤーズ スクイブ カンパニー ７，８−シクロプロパタキサン類
US5478854A (en) * 1992-10-01 1995-12-26 Bristol-Myers Squibb Company Deoxy taxols
US5973160A (en) * 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
US5646176A (en) * 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
US6054136A (en) * 1993-09-30 2000-04-25 Gattefosse S.A. Orally administrable composition capable of providing enhanced bioavailability when ingested
US6458373B1 (en) * 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
IL131217A0 (en) * 1998-03-10 2001-01-28 Napro Biotherapeutics Inc Novel methods and compositions for delivery of taxanes
CA2326485C (en) * 1998-04-01 2008-12-09 Rtp Pharma Inc. Anticancer compositions
EP1185301A1 (de) * 1999-05-24 2002-03-13 Sonus Pharmaceuticals, Inc. Trägeremulsion für schwerlösliche arzneistoffe
US6136846A (en) * 1999-10-25 2000-10-24 Supergen, Inc. Formulation for paclitaxel
NZ539046A (en) * 2001-01-18 2006-11-30 Pharmacia & Upjohn Co Llc Chemotherapeutic self-emulsifying microemulsion compositions of paclitaxel with improved oral bioavailability
US20040092428A1 (en) * 2001-11-27 2004-05-13 Hongming Chen Oral pharmaceuticals formulation comprising paclitaxel, derivatives and methods of administration thereof
GEP20063806B (en) * 2001-12-20 2006-04-25 Bristol Myers Squibb Co Pharmaceutical compositions of orally active taxane derivatives having enhanced bioavailability
JP2005523295A (ja) * 2002-03-01 2005-08-04 ノバガリ、ファルマ、エスアー 難溶性薬剤の自己乳化型薬物送達システム
KR20090072980A (ko) * 2007-12-28 2009-07-02 서울옵토디바이스주식회사 발광 다이오드 및 그 제조방법

Also Published As

Publication number Publication date
AU2004262496A1 (en) 2005-02-17
TW200517104A (en) 2005-06-01
AU2004262496B2 (en) 2009-02-05
WO2005013968A1 (en) 2005-02-17
KR101143341B1 (ko) 2012-05-24
IN2006CH00198A (de) 2007-06-08
HK1091743A1 (en) 2007-01-26
MX260260B (es) 2008-09-04
JP2009513558A (ja) 2009-04-02
MY137965A (en) 2009-04-30
CN1826110A (zh) 2006-08-30
EP1648440B1 (de) 2008-03-12
AR045996A1 (es) 2005-11-23
BRPI0412759A (pt) 2006-09-26
ES2303642T3 (es) 2008-08-16
EP1648440A1 (de) 2006-04-26
KR20060037370A (ko) 2006-05-03
MXPA06000636A (es) 2006-04-19
CA2532667A1 (en) 2005-02-17
CN1826110B (zh) 2010-05-12
DE602004012413T2 (de) 2009-03-12
IL173110A0 (en) 2006-06-11
PT1648440E (pt) 2008-06-24
DE602004012413D1 (de) 2008-04-24
EP1498120A1 (de) 2005-01-19
TWI342774B (en) 2011-06-01
IN229997B (de) 2009-03-27
IL173110A (en) 2011-04-28
US20050070496A1 (en) 2005-03-31
DK1648440T3 (da) 2008-07-14
JP5116306B2 (ja) 2013-01-09

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