ATE3865T1 - Hydantoinamine und deren pharmazeutische zusammensetzungen. - Google Patents
Hydantoinamine und deren pharmazeutische zusammensetzungen.Info
- Publication number
- ATE3865T1 ATE3865T1 AT81300521T AT81300521T ATE3865T1 AT E3865 T1 ATE3865 T1 AT E3865T1 AT 81300521 T AT81300521 T AT 81300521T AT 81300521 T AT81300521 T AT 81300521T AT E3865 T1 ATE3865 T1 AT E3865T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- analogs
- amino
- hydantoinamins
- pharmaceutical compositions
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/120,944 US4248882A (en) | 1980-02-12 | 1980-02-12 | Treating diabetes-associated complications with hydantoin amines |
EP81300521A EP0034063B1 (de) | 1980-02-12 | 1981-02-09 | Hydantoinamine und deren pharmazeutische Zusammensetzungen |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE3865T1 true ATE3865T1 (de) | 1983-07-15 |
Family
ID=22393428
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT81300521T ATE3865T1 (de) | 1980-02-12 | 1981-02-09 | Hydantoinamine und deren pharmazeutische zusammensetzungen. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4248882A (de) |
EP (1) | EP0034063B1 (de) |
JP (1) | JPS56127379A (de) |
AT (1) | ATE3865T1 (de) |
DE (1) | DE3160449D1 (de) |
DK (1) | DK156400C (de) |
GR (1) | GR73856B (de) |
IE (1) | IE50895B1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4490381A (en) * | 1979-11-13 | 1984-12-25 | Imperial Chemical Industries Plc | 1'-Substituted spiro[imidazolidine-4,3'-indoline]2,2',5-triones |
EP0065393B1 (de) * | 1981-05-12 | 1984-12-27 | Imperial Chemical Industries Plc | Pyrrolderivate |
US4556670A (en) * | 1982-12-06 | 1985-12-03 | Pfizer Inc. | Spiro-3-hetero-azolones for treatment of diabetic complications |
US4474967A (en) * | 1983-04-27 | 1984-10-02 | Pfizer Inc. | 8-Deutero and 8-tritio-substituted derivatives of D-4S-6-fluoro-spiro-[chroman-4,4'-imidazolidine]-2',5'-dione |
US4464380A (en) * | 1983-05-25 | 1984-08-07 | Pfizer Inc. | Imidazolidinedione derivatives |
DK277484A (da) * | 1983-06-23 | 1984-12-24 | Hoffmann La Roche | Thiazolidinderivater |
EP0172352B1 (de) * | 1984-06-22 | 1990-08-29 | Beecham Group Plc | Wirksame Benzopyranverbindungen |
US4680306A (en) * | 1984-07-20 | 1987-07-14 | Pfizer Inc. | Sprio-imidazolones for treatment of diabetes complications |
ATE37371T1 (de) * | 1984-08-20 | 1988-10-15 | Pfizer | Verfahren zur herstellung asymmetrischer hydantoine. |
US5340829A (en) * | 1984-11-20 | 1994-08-23 | Washington Research Foundation | Immunoregulatory agents |
US4966911A (en) * | 1984-11-20 | 1990-10-30 | Washington Research Foundation | Immunoregulatory agents |
JPH0772190B2 (ja) * | 1985-02-26 | 1995-08-02 | エーザイ株式会社 | ヒダントイン誘導体 |
US4575507A (en) * | 1985-05-29 | 1986-03-11 | Pfizer Inc. | Spiro-imidazolidines as aldose reductase inhibitors and their pharmaceutical use |
US4762839A (en) * | 1985-06-06 | 1988-08-09 | Tanabe Seiyaku Co., Ltd. | Quinazolinone copmpounds useful for the prophyloxis and treatment of diabetic complications |
JPS63126881A (ja) * | 1986-11-14 | 1988-05-30 | Sanwa Kagaku Kenkyusho Co Ltd | ヒダントイン誘導体、その塩、これらの製法並びに該化合物を有効成分とする糖尿病合併症の予防及び治療剤 |
JPS63132889A (ja) * | 1986-11-21 | 1988-06-04 | Tanabe Seiyaku Co Ltd | キナゾリノン誘導体 |
MX12896A (es) * | 1987-09-04 | 1993-06-01 | Pfizer | Procedimiento para preparar un compuesto de espiro-heteroazolonas |
US4952694A (en) * | 1988-07-27 | 1990-08-28 | Pfizer Inc. | Novel resolution process for racemic spiro-hydantoins |
EP0536119A4 (en) * | 1989-02-10 | 1993-08-04 | Washington Research Foundation | Immunoregulatory agents |
JP2678499B2 (ja) * | 1989-08-09 | 1997-11-17 | 日本臓器製薬 株式会社 | ***毒素低下剤 |
JPH03215435A (ja) * | 1990-01-12 | 1991-09-20 | Sanwa Kagaku Kenkyusho Co Ltd | アルドース還元酵素阻害剤を主成分とする潰瘍治療剤 |
EP1375485B1 (de) * | 2001-04-05 | 2011-04-20 | Nissan Chemical Industries, Ltd. | Verfahren zur herstellung von 7-chinolinyl-3,5-dihydroxyhept-6-enoat |
US7795203B2 (en) * | 2002-09-30 | 2010-09-14 | Babizhayev Mark A | Method for topical treatment of eye disease and composition and device for said treatment |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1135915B (de) * | 1961-06-29 | 1962-09-06 | Asta Werke Ag Chem Fab | Verfahren zur Herstellung neuer, antikonvulsiv wirksamer Spirohydantoine |
US3534037A (en) * | 1968-05-10 | 1970-10-13 | Smithkline Corp | Spiro-(imidazolidine and pyrimidine-quinoline and cyclopropa(c)quinoline) compounds |
US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
US4117230A (en) * | 1976-10-18 | 1978-09-26 | Pfizer Inc. | Hydantoin derivatives as therapeutic agents |
US4177282A (en) * | 1977-05-23 | 1979-12-04 | Pfizer Inc. | Hydantoin therapeutic agents |
US4130714A (en) * | 1977-05-23 | 1978-12-19 | Pfizer Inc. | Hydantoin therapeutic agents |
US4176185A (en) * | 1979-01-22 | 1979-11-27 | Pfizer Inc. | Spiro-quinolylhydantoins |
US4181729A (en) * | 1979-03-21 | 1980-01-01 | Pfizer Inc. | Phenyl or phenoxy substituted spiro-imidazolidinedione derivatives |
-
1980
- 1980-02-12 US US06/120,944 patent/US4248882A/en not_active Expired - Lifetime
-
1981
- 1981-02-09 AT AT81300521T patent/ATE3865T1/de not_active IP Right Cessation
- 1981-02-09 EP EP81300521A patent/EP0034063B1/de not_active Expired
- 1981-02-09 DE DE8181300521T patent/DE3160449D1/de not_active Expired
- 1981-02-10 JP JP1886581A patent/JPS56127379A/ja active Granted
- 1981-02-11 IE IE261/81A patent/IE50895B1/en unknown
- 1981-02-11 GR GR64101A patent/GR73856B/el unknown
- 1981-02-11 DK DK056581A patent/DK156400C/da not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DE3160449D1 (en) | 1983-07-28 |
JPS6237636B2 (de) | 1987-08-13 |
EP0034063A1 (de) | 1981-08-19 |
DK56581A (da) | 1981-08-13 |
IE810261L (en) | 1981-08-12 |
US4248882A (en) | 1981-02-03 |
DK156400B (da) | 1989-08-14 |
JPS56127379A (en) | 1981-10-06 |
IE50895B1 (en) | 1986-08-06 |
EP0034063B1 (de) | 1983-06-22 |
DK156400C (da) | 1990-01-08 |
GR73856B (de) | 1984-05-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE3865T1 (de) | Hydantoinamine und deren pharmazeutische zusammensetzungen. | |
SE7906949L (sv) | Nya spiro-oxazolidindioner | |
NO890259D0 (no) | Fremgangsmaate for fremstilling av terapeutisk aktive etylfenoksyacetamider. | |
IE790088L (en) | Thienohydantoin derivatives | |
CO4930267A1 (es) | Composiciones que contienen cisteina de n acetilo utiles en el tratamiento de heridas cronicas | |
AU581442B2 (en) | 2-substituted-1, 3-propylidenediphosphonate derivatives, the process for their preparation and pharmaceutical compositions containing them | |
KR920017655A (ko) | 상처의 치료를 촉진시키기 위한 약학 조성물 | |
SE7909439L (sv) | Spiro-polycykliska imidazolidindionderivat | |
ES2089136T3 (es) | Tratamiento de enfermedades inflamatorias con la ayuda de derivados 15-ceto-prostaglandinas. | |
AU5917390A (en) | Pharmaceutical composition for topic use for the therapeutical treatment of capillary fragility | |
BR9611276A (pt) | Composto formulação farmacêutica processo para tratamento ou profilaxia de doenças ou condições de seres humanos e uso de um composto | |
DE59010302D1 (de) | R-(-)-1-(5-Hydroxyhexyl)-3-methyl-7-propylxanthin, Verfahren zu dessen Herstellung und diese Verbindung enthaltende Arzneimittel | |
DK0378146T3 (da) | Polyamin-derivater som antineoplastiske midler | |
KR910018028A (ko) | 15- 데히드록시-16-옥소프로스타글란딘 화합물에 의한 생화학적 치료 | |
IL70690A (en) | 5-(2-alkoxyphenyl)thiazolidinediones and pharmaceutical compositions containing them | |
FI884911A (fi) | Laekemedel, i dessa saosom aktiva aemnen befintliga fosforin innehaollande 2-isoxazoliner och isoxazoler samt foerfarande foer framstaellning av dessa heterocykliska foereningar. | |
SE8002244L (sv) | Nytt 1alfa,25-dihydroxi-cholekalciferolderivat, sett for framstellning samt anvendning derav som lekemedel och farmaceutiska kompositioner inehallande denna forening | |
IE800672L (en) | Spiro-quinolone hydantoins | |
ITMI911845A1 (it) | Uso dei derivati dell'acido benzimidazolin-2-oxo-1-carbossilico. | |
MX9302929A (es) | Derivados de tetrahidro y perhidroisoquinolina y medios terapeuticos que los contienen. | |
NO165399C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive (5r,6s)-6-((r)-1-hydroksyetyl)-penem-derivater. | |
AU4246189A (en) | Medicament for the treatment of diseases caused by retroviruses | |
ATE109454T1 (de) | Catecholaminester. | |
IT1243368B (it) | Uso del bendazac e dei suoi sali farmaceuticamente accettabili |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |