ATE370728T1 - Antagonisten des gardos-kanals - Google Patents

Antagonisten des gardos-kanals

Info

Publication number: ATE370728T1
Authority: AT; Austria
Prior art keywords: antagonists; gardos channel; gardos; channel
Prior art date: 1999-02-23

Application number

AT00907283T

Other languages

English (en)

Inventor

Grant Mcnaughton-Smith

Gregory Rigdon

Jonathan Stocker

Original Assignee

Icagen Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-02-23

Filing date

2000-02-10

Publication date

2007-09-15

2000-02-10 Application filed by Icagen Inc filed Critical Icagen Inc

2007-09-15 Application granted granted Critical

2007-09-15 Publication of ATE370728T1 publication Critical patent/ATE370728T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/65—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
- C07C233/11—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Hematology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT00907283T 1999-02-23 2000-02-10 Antagonisten des gardos-kanals ATE370728T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US13551199P	1999-02-23	1999-02-23
US09/386,601 US6288122B1 (en)	1999-02-23	1999-08-31	Gardos channel antagonists

Publications (1)

Publication Number	Publication Date
ATE370728T1 true ATE370728T1 (de)	2007-09-15

Family

ID=26833406

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT00907283T ATE370728T1 (de)	1999-02-23	2000-02-10	Antagonisten des gardos-kanals

Country Status (16)

Country	Link
US (1)	US6288122B1 (de)
EP (1)	EP1158971B1 (de)
JP (2)	JP4038337B2 (de)
KR (1)	KR100705726B1 (de)
CN (1)	CN1193748C (de)
AP (1)	AP1465A (de)
AT (1)	ATE370728T1 (de)
AU (1)	AU762039B2 (de)
BR (1)	BR0008416A (de)
CA (1)	CA2371857C (de)
DE (1)	DE60036093T2 (de)
ES (1)	ES2291191T3 (de)
HK (1)	HK1045262B (de)
IL (2)	IL145012A0 (de)
OA (1)	OA11838A (de)
WO (1)	WO2000050026A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003004010A1 (en) *	2001-07-06	2003-01-16	Poseidon Pharmaceuticals A/S	Carbonylamino derivatives useful for obtaining immune regulation
DE60322019D1 (de) *	2002-01-04	2008-08-21	Neurosearch As	Kaliumkanal-modulatoren
CA2477392A1 (en) *	2002-02-28	2003-09-12	Icagen, Inc.	Methods for treating diseases related to intraocular pressure
WO2005003143A1 (en) *	2003-07-03	2005-01-13	Poseidon Pharmaceuticals A/S	Novel potassium channel modulators
WO2005003094A1 (en) *	2003-07-03	2005-01-13	Poseidon Pharmaceuticals A/S	Diarylmethyl derivatives as potassium channel modulators
EP1861356A1 (de) *	2005-02-01	2007-12-05	Icagen, Inc.	Imine als ionenkanalmodulatoren
US20100056637A1 (en) *	2005-12-20	2010-03-04	Icagen, Inc.	Treatment methods using triaryl methane compounds
WO2007075849A2 (en) *	2005-12-20	2007-07-05	Icagen, Inc.	Treatment methods using triaryl methane compounds
EP2322164A3 (de)	2007-08-24	2011-12-07	NeuroSearch A/S	Carbonylamino-Derivate zur Behandlung von entzündlicher Darmerkrankung
US20090076157A1 (en) *	2007-09-15	2009-03-19	Protia, Llc	Deuterium-enriched senicapoc
ES2636563T3 (es)	2008-04-09	2017-10-06	Cerus Corporation	Método de reducción de la deshidratación en una composición de glóbulos rojos
MX2011004946A (es)	2008-11-10	2011-06-16	Boehringer Ingelheim Int	Composiciones y metodos para modular la fusion celula-celula mediante canales de potasio de conductancia intermedia activados por calcio.
WO2016134353A1 (en) *	2015-02-20	2016-08-25	Children's Medical Center Corporation	Methods for treating malaria using potassium channel inhibitors
EP3106155A1 (de) *	2015-06-15	2016-12-21	Universite d'Aix Marseille	Behandlung und diagnose der erblichen xerokytose
US11439607B2 (en) *	2016-10-25	2022-09-13	Paracelsus Neuroscience I, LLC	Use of senicapoc for treatment of neuropathic pain
WO2018162426A1 (en)	2017-03-06	2018-09-13	INSERM (Institut National de la Santé et de la Recherche Médicale)	Treatment and diagnosis of hereditary xerocytosis
WO2020198939A1 (zh) *	2019-03-29	2020-10-08	深圳仁泰医药科技有限公司	2,2-双(4-氟苯基)-2-苯乙酰胺的晶型a及其制备方法和应用
US20230045322A1 (en) *	2019-07-29	2023-02-09	Paracelsus Neuroscience II, LLC	Use of senicapoc for treatment of stroke
WO2022015893A2 (en) *	2020-07-14	2022-01-20	Adimabio Llc	Compositions comprising gardos channel antagonists and their uses
WO2022124900A1 (en)	2020-12-11	2022-06-16	Sanquin Innovatie B.V.	Treatment and prevention of anaemia of inflammation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5273992A (en)	1992-11-02	1993-12-28	Beth Israel Hospital Assoc. Inc.	Method for reducing sickle erythrocyte dehydration and delaying the occurrence of erythrocyte sickling in-situ
BR9708230A (pt)	1996-03-20	2000-01-04	Harvard College	Compostos de triaril metano, composição farmacêutica, e métodos de inibição do transporte de potássio ativado por cálcio de uma célula, para reduzir a desidrataçào de eritrócito falciforme e/ou retaradar a ocorrência de afoiçamento ou deformação de eritrócitos, e tratamento ou prevenção de doença, de inibição da proliferação celular em mamìferos, e de tratamento ou prevenção de uma desordem.

1999
- 1999-08-31 US US09/386,601 patent/US6288122B1/en not_active Expired - Lifetime
2000
- 2000-02-10 ES ES00907283T patent/ES2291191T3/es not_active Expired - Lifetime
- 2000-02-10 JP JP2000600638A patent/JP4038337B2/ja not_active Expired - Fee Related
- 2000-02-10 WO PCT/US2000/003663 patent/WO2000050026A1/en active IP Right Grant
- 2000-02-10 CN CNB008054525A patent/CN1193748C/zh not_active Expired - Fee Related
- 2000-02-10 AU AU28807/00A patent/AU762039B2/en not_active Ceased
- 2000-02-10 AT AT00907283T patent/ATE370728T1/de active
- 2000-02-10 EP EP00907283A patent/EP1158971B1/de not_active Expired - Lifetime
- 2000-02-10 DE DE60036093T patent/DE60036093T2/de not_active Expired - Lifetime
- 2000-02-10 OA OA1200100220A patent/OA11838A/en unknown
- 2000-02-10 BR BR0008416-6A patent/BR0008416A/pt not_active IP Right Cessation
- 2000-02-10 KR KR1020017010707A patent/KR100705726B1/ko not_active IP Right Cessation
- 2000-02-10 CA CA002371857A patent/CA2371857C/en not_active Expired - Fee Related
- 2000-02-10 AP APAP/P/2001/002268A patent/AP1465A/en active
- 2000-02-10 IL IL14501200A patent/IL145012A0/xx active IP Right Grant
2001
- 2001-08-21 IL IL145012A patent/IL145012A/en not_active IP Right Cessation
2002
- 2002-09-16 HK HK02106773.8A patent/HK1045262B/zh not_active IP Right Cessation
2007
- 2007-05-02 JP JP2007121967A patent/JP2007262075A/ja active Pending

Also Published As

Publication number	Publication date
ES2291191T3 (es)	2008-03-01
AP1465A (en)	2005-09-22
JP4038337B2 (ja)	2008-01-23
HK1045262A1 (en)	2002-11-22
AP2001002268A0 (en)	2001-09-30
JP2007262075A (ja)	2007-10-11
US6288122B1 (en)	2001-09-11
DE60036093D1 (de)	2007-10-04
KR20020002393A (ko)	2002-01-09
IL145012A (en)	2006-12-10
BR0008416A (pt)	2002-01-29
EP1158971A1 (de)	2001-12-05
IL145012A0 (en)	2002-06-30
AU762039B2 (en)	2003-06-19
EP1158971A4 (de)	2003-04-16
CA2371857C (en)	2008-07-29
KR100705726B1 (ko)	2007-04-11
CN1344158A (zh)	2002-04-10
AU2880700A (en)	2000-09-14
EP1158971B1 (de)	2007-08-22
DE60036093T2 (de)	2008-05-15
WO2000050026A1 (en)	2000-08-31
JP2002537331A (ja)	2002-11-05
CA2371857A1 (en)	2000-08-31
HK1045262B (zh)	2005-07-29
OA11838A (en)	2005-08-22
CN1193748C (zh)	2005-03-23

Legal Events

Date

Code

Title

Description

2008-01-15

UEP

Publication of translation of european patent specification

Ref document number: 1158971

Country of ref document: EP

Publication	Publication Date	Title
ATE370728T1 (de)	2007-09-15	Antagonisten des gardos-kanals
AR028253A1 (es)	2003-04-30	Inhibidores de la glucogeno fosforilasa
ATE512594T1 (de)	2011-07-15	Verbesserung des zustandes älterer haustiere
ATE392890T1 (de)	2008-05-15	Hydrogel-gesteuerte dosierungsform
ATE247398T1 (de)	2003-09-15	Zahnbürste
DE60009127T2 (de)	2004-10-21	Zahnbürste
DK1067905T3 (da)	2003-02-03	Bruseformuleringer
DE60010041D1 (de)	2004-05-27	Zahnbürste
ATE502923T1 (de)	2011-04-15	Amid-verbindungen
EE05020B1 (et)	2008-06-16	Glburiidi ravimkoostis
DE10084428T1 (de)	2002-05-08	Zahnbürste
DE60007530D1 (de)	2004-02-05	Oral wirksame androgene
DK1022396T3 (da)	2005-01-17	Bruserkombination
DE50015795D1 (de)	2009-12-24	Sektionaltor
DE50009595D1 (de)	2005-03-31	Zahnbürste
DE50006709D1 (de)	2004-07-08	Zahnbürste
PT1287095E (pt)	2004-10-29	Mistura de gasolina-oxigenato
ES1045691Y (es)	2001-10-01	Ducha
ID30381A (id)	2001-11-29	Penggunaan arilalkanoilpiridazina
PT1232141E (pt)	2004-12-31	Eteres de o-desmetil-venlafaxina
DE60006028D1 (de)	2003-11-27	Aminobutyronitril Mischung
ATA36099A (de)	2001-01-15	Stoffgemisch
ITMI20000412A0 (it)	2000-03-02	Doccia
DK1133361T3 (da)	2005-06-27	Brusehoved
FIU990082U0 (fi)	1999-02-18	Siemenseos