ATE362758T1 - Indomethacin-amidderivate zur antiangiogenen und/oder antitumorigen verwendung - Google Patents

Indomethacin-amidderivate zur antiangiogenen und/oder antitumorigen verwendung

Info

Publication number
ATE362758T1
ATE362758T1 AT99967417T AT99967417T ATE362758T1 AT E362758 T1 ATE362758 T1 AT E362758T1 AT 99967417 T AT99967417 T AT 99967417T AT 99967417 T AT99967417 T AT 99967417T AT E362758 T1 ATE362758 T1 AT E362758T1
Authority
AT
Austria
Prior art keywords
amide derivatives
antitumorous
antiangiogenic
indomethacin
indomethacin amide
Prior art date
Application number
AT99967417T
Other languages
English (en)
Inventor
Amit Kalgutkar
Lawrence Marnett
Original Assignee
Univ Vanderbilt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Vanderbilt filed Critical Univ Vanderbilt
Application granted granted Critical
Publication of ATE362758T1 publication Critical patent/ATE362758T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
AT99967417T 1999-01-07 1999-12-16 Indomethacin-amidderivate zur antiangiogenen und/oder antitumorigen verwendung ATE362758T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/226,693 US6207700B1 (en) 1999-01-07 1999-01-07 Amide derivatives for antiangiogenic and/or antitumorigenic use

Publications (1)

Publication Number Publication Date
ATE362758T1 true ATE362758T1 (de) 2007-06-15

Family

ID=22850011

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99967417T ATE362758T1 (de) 1999-01-07 1999-12-16 Indomethacin-amidderivate zur antiangiogenen und/oder antitumorigen verwendung

Country Status (12)

Country Link
US (2) US6207700B1 (de)
EP (1) EP1146788B1 (de)
JP (1) JP2002534362A (de)
CN (1) CN1195515C (de)
AT (1) ATE362758T1 (de)
AU (1) AU760555B2 (de)
BR (1) BR9916800A (de)
CA (1) CA2358289C (de)
DE (1) DE69936150T2 (de)
ES (1) ES2288039T3 (de)
IL (2) IL144127A0 (de)
WO (1) WO2000040088A1 (de)

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WO2010019549A2 (en) * 2008-08-12 2010-02-18 Osteogenex Inc Indoprofen derivatives for promoting bone growth
TWI450715B (zh) * 2010-01-08 2014-09-01 Nat Univ Tsing Hua 治療癌症的芬布芬衍生物
CN101897718A (zh) * 2010-07-13 2010-12-01 山东省医学科学院基础医学研究所 一种肿瘤血管生长抑制剂
US20120022116A1 (en) * 2010-07-20 2012-01-26 Huayun Deng Compositions and methods for the treatment of pathological condition(s) related to gpr35 and/or gpr35-herg complex
EP2768499A4 (de) 2011-10-17 2015-08-26 Univ Vanderbilt Indomethacin-analoga zur behandlung von kastrationsresistentem prostatakrebs
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Also Published As

Publication number Publication date
CN1337850A (zh) 2002-02-27
AU760555B2 (en) 2003-05-15
US6399647B2 (en) 2002-06-04
US6207700B1 (en) 2001-03-27
DE69936150T2 (de) 2008-01-31
DE69936150D1 (de) 2007-07-05
AU2369800A (en) 2000-07-24
ES2288039T3 (es) 2007-12-16
JP2002534362A (ja) 2002-10-15
CN1195515C (zh) 2005-04-06
EP1146788A4 (de) 2003-09-10
EP1146788A1 (de) 2001-10-24
CA2358289A1 (en) 2000-07-13
EP1146788B1 (de) 2007-05-23
WO2000040088A1 (en) 2000-07-13
BR9916800A (pt) 2001-10-23
IL144127A0 (en) 2002-05-23
CA2358289C (en) 2009-12-08
IL144127A (en) 2006-12-10
US20010034361A1 (en) 2001-10-25

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