ATE362534T2 - Menschliche tslp nukleinsäuren und polypeptide - Google Patents

Menschliche tslp nukleinsäuren und polypeptide Download PDF

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Publication number
ATE362534T2
ATE362534T2 AT99960372T AT99960372T ATE362534T2 AT E362534 T2 ATE362534 T2 AT E362534T2 AT 99960372 T AT99960372 T AT 99960372T AT 99960372 T AT99960372 T AT 99960372T AT E362534 T2 ATE362534 T2 AT E362534T2
Authority
AT
Austria
Prior art keywords
polypeptides
nucleic acids
human tslp
tslp nucleic
purified
Prior art date
Application number
AT99960372T
Other languages
English (en)
Inventor
John Sims
Stewart Lyman
Hilary Mckenna
Allison Armstrong
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22322307&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE362534(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunex Corp filed Critical Immunex Corp
Application granted granted Critical
Publication of ATE362534T2 publication Critical patent/ATE362534T2/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5418—IL-7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99960372T 1998-11-13 1999-11-12 Menschliche tslp nukleinsäuren und polypeptide ATE362534T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10845298P 1998-11-13 1998-11-13

Publications (1)

Publication Number Publication Date
ATE362534T2 true ATE362534T2 (de) 2007-06-15

Family

ID=22322307

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99960372T ATE362534T2 (de) 1998-11-13 1999-11-12 Menschliche tslp nukleinsäuren und polypeptide

Country Status (14)

Country Link
US (8) US6555520B2 (de)
EP (1) EP1129190B2 (de)
JP (3) JP4454859B2 (de)
AT (1) ATE362534T2 (de)
AU (1) AU755562B2 (de)
CA (1) CA2349762C (de)
CY (1) CY1106806T1 (de)
DE (1) DE69936105T3 (de)
DK (1) DK1129190T4 (de)
ES (1) ES2288036T5 (de)
IL (3) IL143034A0 (de)
NZ (1) NZ512105A (de)
PT (1) PT1129190E (de)
WO (1) WO2000029581A1 (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030099947A1 (en) 1998-09-21 2003-05-29 Bazan J. Fernando Mammalian cytokines; related reagents and methods
EP2314696A1 (de) * 1998-09-21 2011-04-27 Schering Corporation Therapeutische Verwendungen von humanem Interleukin-B50 Antagonist.
JP4454859B2 (ja) * 1998-11-13 2010-04-21 イミュネックス・コーポレーション ヒトｔｓｌｐｄｎａおよびポリペプチド
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
US7288633B2 (en) * 2001-07-23 2007-10-30 Immunex Corporation Modified human thymic stromal lymphopoietin
NZ533987A (en) * 2002-02-01 2007-04-27 Schering Corp Uses of mammalian cytokine; agonists and antagonists for modulating antigen presenting cell priming of T cells
MXPA06000659A (es) * 2003-07-18 2006-03-30 Schering Corp Tratamiento y diagnostico de neoplasmas usando linfopoyetina estromal timica.
US20050249712A1 (en) * 2004-03-23 2005-11-10 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services Methods for use of TSLP and agonists and antagonists thereof
CA2575721A1 (en) * 2004-07-28 2006-03-02 Tanox, Inc. Thymic stromal lymphopoietin promoter and uses therefor
US20060171943A1 (en) * 2005-02-01 2006-08-03 Amgen Inc. Compositions and methods of treating fibrotic disorders
CA2513350A1 (en) * 2005-03-02 2006-09-02 Sydney West Area Health Service Treatment for multiple sclerosis
BRPI0706530A2 (pt) * 2006-01-13 2011-03-29 Irm Llc métodos e composições para tratamento de doenças alérgicas
GB0603683D0 (en) 2006-02-23 2006-04-05 Novartis Ag Organic compounds
SE532251C2 (sv) * 2006-11-28 2009-11-24 Theravac Pharmaceuticals Ab Nya formuleringar av TSLP för behandling av TH2-medierade inflammatoriska sjukdomar genom vaccinering
UA120027C2 (uk) 2006-12-14 2019-09-25 Шерінг-Плау Лтд. Ізольоване антитіло проти собачого тимусного стромального лімфопоетину (tslp)
CN101605814B (zh) 2006-12-14 2014-02-19 默沙东公司 经工程改造的抗tslp抗体
US8501678B2 (en) 2007-03-06 2013-08-06 Atara Biotherapeutics, Inc. Variant activin receptor polypeptides and uses thereof
TW201718635A (zh) 2007-03-06 2017-06-01 安美基公司 變異之活動素受體多肽及其用途
US7982016B2 (en) * 2007-09-10 2011-07-19 Amgen Inc. Antigen binding proteins capable of binding thymic stromal lymphopoietin
NZ627111A (en) 2008-11-26 2015-10-30 Amgen Inc Variants of activin iib receptor polypeptides and uses thereof
EP2213682A1 (de) 2009-01-30 2010-08-04 Institut Curie TSLP fördert Immunevasion und Persistenz von Viren
US8637019B2 (en) 2009-11-04 2014-01-28 Merck Sharp & Dohme Corp. Engineered anti-TSLP antibody
MX358358B (es) 2011-12-19 2018-08-15 Amgen Inc Polipeptidos de receptores de activina variantes y sus usos.
AR090915A1 (es) 2012-05-04 2014-12-17 Intervet Int Bv Proteina de fusion de proteina linfopoyetina estromal timica canina con la region fc de igg
CA2890706A1 (en) 2012-11-09 2014-05-15 Cornell University Small molecule inhibitors of malt1
UY35148A (es) 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
CN105431455A (zh) 2013-02-01 2016-03-23 圣塔玛丽亚生物疗法公司 抗激活素a化合物对受试者的施用
WO2014144817A2 (en) 2013-03-15 2014-09-18 Amgen Inc. Inhibitory polypeptides specific to wnt inhibitors
WO2014162007A2 (en) * 2013-04-04 2014-10-09 Ieo - Istituto Europeo Di Oncologia Srl Thymic stromal lymphopoietin fragments and uses thereof
EP3712166A1 (de) 2013-09-05 2020-09-23 Amgen Inc. Fc-haltige moleküle mit vorhersagbaren, konsistenten und reproduzierbaren glycoformprofilen
JP6671298B2 (ja) 2014-05-16 2020-03-25 アムジェン インコーポレイテッド Ｔｈ１及びｔｈ２細胞集団を検出するためのアッセイ
MX2016016281A (es) 2014-06-13 2017-03-31 Santa Maria Biotherapeutics Inc Polipeptidos receptores formulados y metodos relacionados.
WO2016148437A1 (ko) * 2015-03-17 2016-09-22 고려대학교 산학협력단 흉선 기질 림프단백질 매개 신호전달을 제어하는 펩타이드 유도체 및 이를 포함하는 알러지 및 천식 질환 예방 및 치료용 약학 조성물
KR101843248B1 (ko) 2015-03-17 2018-03-29 고려대학교 세종산학협력단 흉선 기질 림프단백질 매개 신호전달을 제어하는 펩타이드 유도체 및 이를 포함하는 알러지 및 천식 질환 예방 및 치료용 약학 조성물
HUE053914T2 (hu) 2015-09-09 2021-07-28 Novartis Ag Csecsemõmirigy-stróma eredetû limfopoietinhez (TSLP-hez) kötõdõ ellenanyagok és az ellenanyagok alkalmazására szolgáló eljárások
WO2017042701A1 (en) 2015-09-09 2017-03-16 Novartis Ag Thymic stromal lymphopoietin (tslp)-binding antibodies and methods of using the antibodies
SG11201908328XA (en) 2017-03-14 2019-10-30 Amgen Inc Control of total afucosylated glycoforms of antibodies produced in cell culture
BR112020019559A2 (pt) 2018-03-26 2021-01-12 Amgen Inc. Glicoformas afucosiladas totais de anticorpos produzidos em cultura de células
CN109678957B (zh) * 2018-12-06 2021-04-06 浙江工业大学 一种抗人tslp单克隆抗体及其制备与应用
KR102156335B1 (ko) * 2018-12-28 2020-09-16 (주)메디톡스 외래 단백질을 발현하는 미생물, 및 그의 용도
BR112022005583A2 (pt) 2019-09-26 2022-09-20 Amgen Inc Métodos para a produção de composições de anticorpos
EP4162257A1 (de) 2020-06-04 2023-04-12 Amgen Inc. Beurteilung von reinigungsvorgängen eines biotherapeutischen herstellungsverfahrens
MX2023004364A (es) 2020-10-15 2023-05-03 Amgen Inc Glucanos no emparejados relativos en metodos de produccion de anticuerpos.
WO2022261021A1 (en) 2021-06-07 2022-12-15 Amgen Inc. Using fucosidase to control afucosylation level of glycosylated proteins
AU2022361382A1 (en) 2021-10-05 2024-03-28 Amgen Inc. Fc-gamma receptor ii binding and glycan content
WO2023215725A1 (en) 2022-05-02 2023-11-09 Fred Hutchinson Cancer Center Compositions and methods for cellular immunotherapy

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011912A (en) * 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
JPH07509223A (ja) 1992-04-30 1995-10-12 アムジェン インコーポレイテッド インターロイキン−１媒介疾患および腫瘍壊死因子媒介疾患の治療方法
EP0737071A1 (de) 1993-06-15 1996-10-16 Il- Yang Pharm. Co., Ltd. Anti-sense-oligodeoxynukleotide zu fibrogenen cytokinen und ihre verwendung
GB9702944D0 (en) 1997-02-13 1997-04-02 Univ Manchester Reducing fibrosis
US6982320B2 (en) 1998-03-19 2006-01-03 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
US6844170B1 (en) * 1998-03-19 2005-01-18 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
WO1999047538A1 (en) 1998-03-19 1999-09-23 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
EP2314696A1 (de) * 1998-09-21 2011-04-27 Schering Corporation Therapeutische Verwendungen von humanem Interleukin-B50 Antagonist.
US20030099947A1 (en) * 1998-09-21 2003-05-29 Bazan J. Fernando Mammalian cytokines; related reagents and methods
JP4454859B2 (ja) 1998-11-13 2010-04-21 イミュネックス・コーポレーション ヒトｔｓｌｐｄｎａおよびポリペプチド
AU2396600A (en) 1998-12-30 2000-07-31 Millennium Pharmaceuticals, Inc. Secreted proteins and uses thereof
US20010021380A1 (en) 1999-04-19 2001-09-13 Pluenneke John D. Soluble tumor necrosis factor receptor treatment of medical disorders
EP1282435A2 (de) 2000-05-12 2003-02-12 Immunex Corporation Interleukin-1 inhibitoren zur behandlung von erkrankungen
PT2077279E (pt) 2000-06-28 2012-09-14 Amgen Inc Moléculas do receptor de linfopoietina estromal tímica e suas utilizações
WO2002000723A2 (en) 2000-06-28 2002-01-03 Whitehead Institute For Biomedical Research Thymic stromal lymphopoietin receptor molecules and uses thereof
NZ533987A (en) 2002-02-01 2007-04-27 Schering Corp Uses of mammalian cytokine; agonists and antagonists for modulating antigen presenting cell priming of T cells
HRP20020453A2 (en) 2002-05-23 2003-12-31 Pliva D D 1,3-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediate for preparation thereof
CA2497884C (en) 2002-09-06 2013-10-22 Brian Varnum Therapeutic human anti-il-1r1 monoclonal antibody
MXPA06000659A (es) 2003-07-18 2006-03-30 Schering Corp Tratamiento y diagnostico de neoplasmas usando linfopoyetina estromal timica.
US20050249712A1 (en) * 2004-03-23 2005-11-10 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services Methods for use of TSLP and agonists and antagonists thereof
CA2577631A1 (en) 2004-08-20 2006-03-02 Amgen Inc. Methods and compositions for treating allergic inflammation
BRPI0706530A2 (pt) 2006-01-13 2011-03-29 Irm Llc métodos e composições para tratamento de doenças alérgicas
GB0603683D0 (en) 2006-02-23 2006-04-05 Novartis Ag Organic compounds
CN101605814B (zh) 2006-12-14 2014-02-19 默沙东公司 经工程改造的抗tslp抗体
KR20100034015A (ko) 2007-06-20 2010-03-31 아이알엠 엘엘씨 알레르기 질환 치료를 위한 방법 및 조성물
JP5640146B2 (ja) † 2011-04-11 2014-12-10 クラリオン株式会社 位置算出方法及び位置算出装置

Also Published As

Publication number Publication date
IL143034A (en) 2009-07-20
DE69936105T2 (de) 2008-01-24
US6555520B2 (en) 2003-04-29
DE69936105D1 (de) 2007-06-28
US20100266601A1 (en) 2010-10-21
NZ512105A (en) 2004-04-30
US9346870B2 (en) 2016-05-24
AU1726600A (en) 2000-06-05
US20120014961A1 (en) 2012-01-19
EP1129190B1 (de) 2007-05-16
IL143034A0 (en) 2002-04-21
JP2002530079A (ja) 2002-09-17
US20060223754A1 (en) 2006-10-05
US7304144B2 (en) 2007-12-04
US20090017034A1 (en) 2009-01-15
DK1129190T3 (da) 2007-09-24
IL195812A0 (en) 2011-08-01
US7405058B2 (en) 2008-07-29
US20020146819A1 (en) 2002-10-10
IL195812A (en) 2012-04-30
US20130225490A1 (en) 2013-08-29
CY1106806T1 (el) 2012-05-23
DE69936105T3 (de) 2017-07-27
US8444979B2 (en) 2013-05-21
JP4454859B2 (ja) 2010-04-21
DK1129190T4 (en) 2017-04-03
US7786271B2 (en) 2010-08-31
ES2288036T5 (es) 2017-07-06
US20030181360A1 (en) 2003-09-25
EP1129190B2 (de) 2017-01-11
ES2288036T3 (es) 2007-12-16
JP2013078331A (ja) 2013-05-02
JP5632155B2 (ja) 2014-11-26
AU755562B2 (en) 2002-12-12
PT1129190E (pt) 2007-08-08
CA2349762A1 (en) 2000-05-25
US20150005226A1 (en) 2015-01-01
CA2349762C (en) 2013-12-24
EP1129190A1 (de) 2001-09-05
JP2010088445A (ja) 2010-04-22
WO2000029581A1 (en) 2000-05-25

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