ATE336495T1 - Pyrazolopyrimidine als crf rezeptor-antagonisten - Google Patents

Pyrazolopyrimidine als crf rezeptor-antagonisten

Info

Publication number: ATE336495T1
Authority: AT; Austria
Prior art keywords: pyrazolopyrimidines; receptor antagonists; crf receptor; crf; antagonists
Prior art date: 1996-02-07

Application number

AT97902295T

Other languages

English (en)

Inventor

Chen Chen

Thomas R Webb

James R Mccarthy

Terence J Moran

Keith M Wilcoxen

Original Assignee

Neurocrine Biosciences Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-02-07

Filing date

1997-01-30

Publication date

2006-09-15

1997-01-30 Application filed by Neurocrine Biosciences Inc filed Critical Neurocrine Biosciences Inc

2006-09-15 Application granted granted Critical

2006-09-15 Publication of ATE336495T1 publication Critical patent/ATE336495T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/14—Antitussive agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A61P25/32—Alcohol-abuse
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P3/00—Drugs for disorders of the metabolism
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems

AT97902295T 1996-02-07 1997-01-30 Pyrazolopyrimidine als crf rezeptor-antagonisten ATE336495T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US1127996P	1996-02-07	1996-02-07
US2768896P	1996-10-08	1996-10-08

Publications (1)

Publication Number	Publication Date
ATE336495T1 true ATE336495T1 (de)	2006-09-15

Family

ID=26682204

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97902295T ATE336495T1 (de)	1996-02-07	1997-01-30	Pyrazolopyrimidine als crf rezeptor-antagonisten

Country Status (27)

Country	Link
EP (1)	EP0880523B1 (de)
JP (2)	JP3356291B2 (de)
KR (1)	KR100421626B1 (de)
CN (1)	CN1090189C (de)
AR (1)	AR008577A1 (de)
AT (1)	ATE336495T1 (de)
AU (1)	AU713673B2 (de)
BG (1)	BG102349A (de)
BR (1)	BR9707391A (de)
CA (1)	CA2233285C (de)
CZ (1)	CZ244598A3 (de)
DE (2)	DE880523T1 (de)
DK (1)	DK0880523T3 (de)
EA (1)	EA000803B1 (de)
EE (1)	EE04282B1 (de)
ES (1)	ES2168237T3 (de)
HU (1)	HUP9900575A3 (de)
ID (1)	ID15905A (de)
IL (1)	IL123835A0 (de)
NO (1)	NO310292B1 (de)
NZ (1)	NZ330119A (de)
PL (1)	PL191271B1 (de)
PT (1)	PT880523E (de)
SK (1)	SK106398A3 (de)
TR (1)	TR199800792T2 (de)
TW (1)	TW449599B (de)
WO (1)	WO1997029109A1 (de)

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US11708372B2 (en)	2021-11-19	2023-07-25	Spruce Biosciences, Inc.	Crystalline composition of tildacerfont and methods of use and preparation thereof

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JPS6157587A (ja) *	1984-08-29	1986-03-24	Shionogi & Co Ltd	縮合複素環誘導体および抗潰瘍剤
JPH0211753A (ja) *	1988-06-29	1990-01-16	Raimuzu:Kk	ＴｉＡｌ系複合部材及びその製造方法
TW370529B (en) *	1992-12-17	1999-09-21	Pfizer	Pyrazolopyrimidines

1997
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Also Published As

Publication number	Publication date
EA000803B1 (ru)	2000-04-24
AU1599197A (en)	1997-08-28
PL191271B1 (pl)	2006-04-28
PL327284A1 (en)	1998-12-07
DE880523T1 (de)	2002-07-04
IL123835A0 (en)	1998-10-30
CZ244598A3 (cs)	1998-10-14
DK0880523T3 (da)	2007-03-26
JP3356291B2 (ja)	2002-12-16
NO981357D0 (no)	1998-03-25
EE04282B1 (et)	2004-04-15
JP2000503661A (ja)	2000-03-28
ID15905A (id)	1997-08-14
NO981357L (no)	1998-08-03
HUP9900575A3 (en)	2001-11-28
NZ330119A (en)	2000-02-28
CA2233285C (en)	2006-07-04
ES2168237T1 (es)	2002-06-16
WO1997029109A1 (en)	1997-08-14
TW449599B (en)	2001-08-11
TR199800792T2 (xx)	1998-07-21
HUP9900575A2 (hu)	1999-06-28
SK106398A3 (en)	1998-12-02
CN1205009A (zh)	1999-01-13
AU713673B2 (en)	1999-12-09
BG102349A (en)	1999-02-26
NO310292B1 (no)	2001-06-18
ES2168237T3 (es)	2007-04-01
CN1090189C (zh)	2002-09-04
CA2233285A1 (en)	1997-08-14
JP2002121194A (ja)	2002-04-23
EE9800124A (et)	1998-10-15
KR19990067391A (ko)	1999-08-16
AR008577A1 (es)	2000-02-09
DE69736513T2 (de)	2007-04-05
EP0880523B1 (de)	2006-08-16
EA199800394A1 (ru)	1998-10-29
PT880523E (pt)	2007-01-31
KR100421626B1 (ko)	2004-05-20
DE69736513D1 (de)	2006-09-28
BR9707391A (pt)	1999-07-20
EP0880523A1 (de)	1998-12-02

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