ATE314062T1 - Zusammensetzungen zur abgabe von cortisolantagonisten - Google Patents
Zusammensetzungen zur abgabe von cortisolantagonistenInfo
- Publication number
- ATE314062T1 ATE314062T1 AT01901275T AT01901275T ATE314062T1 AT E314062 T1 ATE314062 T1 AT E314062T1 AT 01901275 T AT01901275 T AT 01901275T AT 01901275 T AT01901275 T AT 01901275T AT E314062 T1 ATE314062 T1 AT E314062T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions
- delivering
- complications
- mammal
- metabolic syndrome
- Prior art date
Links
- JYGXADMDTFJGBT-VWUMJDOOSA-N hydrocortisone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 JYGXADMDTFJGBT-VWUMJDOOSA-N 0.000 title abstract 6
- 239000005557 antagonist Substances 0.000 title abstract 3
- 229960000890 hydrocortisone Drugs 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 3
- 241000124008 Mammalia Species 0.000 abstract 2
- 208000001145 Metabolic Syndrome Diseases 0.000 abstract 2
- 201000000690 abdominal obesity-metabolic syndrome Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000001072 type 2 diabetes mellitus Diseases 0.000 abstract 2
- 208000002249 Diabetes Complications Diseases 0.000 abstract 1
- 238000013270 controlled release Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 208000024891 symptom Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/02—Halogenated hydrocarbons
- A61K31/025—Halogenated hydrocarbons carbocyclic
- A61K31/03—Halogenated hydrocarbons carbocyclic aromatic
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
- A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
- A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0001449.8A GB0001449D0 (en) | 2000-01-21 | 2000-01-21 | Compositions |
PCT/GB2001/000201 WO2001052833A1 (en) | 2000-01-21 | 2001-01-19 | Compositions for delivery of a cortisol antagonist |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE314062T1 true ATE314062T1 (de) | 2006-01-15 |
Family
ID=9884138
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01901275T ATE314062T1 (de) | 2000-01-21 | 2001-01-19 | Zusammensetzungen zur abgabe von cortisolantagonisten |
Country Status (19)
Country | Link |
---|---|
US (1) | US20030190357A1 (de) |
EP (1) | EP1251843B1 (de) |
JP (1) | JP2003520788A (de) |
KR (1) | KR20020069262A (de) |
CN (1) | CN1416340A (de) |
AT (1) | ATE314062T1 (de) |
AU (1) | AU783281B2 (de) |
CA (1) | CA2397065A1 (de) |
CZ (1) | CZ20022439A3 (de) |
DE (1) | DE60116256T2 (de) |
GB (1) | GB0001449D0 (de) |
HU (1) | HUP0204340A3 (de) |
MX (1) | MXPA02007117A (de) |
NO (1) | NO20023473L (de) |
NZ (1) | NZ519993A (de) |
PL (1) | PL363218A1 (de) |
RU (1) | RU2002119568A (de) |
SK (1) | SK10482002A3 (de) |
WO (1) | WO2001052833A1 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE0001899D0 (sv) | 2000-05-22 | 2000-05-22 | Pharmacia & Upjohn Ab | New compounds |
GB2375958B (en) | 2001-04-09 | 2005-03-02 | George Margetts | The use of steroids to lower the levels of cortisol |
GB0118300D0 (en) * | 2001-07-26 | 2001-09-19 | Cortendo Ab | Formulations |
US6673369B2 (en) | 2001-08-29 | 2004-01-06 | Ranbaxy Laboratories Limited | Controlled release formulation |
US7094792B2 (en) | 2001-11-22 | 2006-08-22 | Biovitrum Ab | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 |
FR2838349B1 (fr) * | 2002-04-15 | 2004-06-25 | Laurence Paris | Compositions liquides pour capsules molle a liberation prolongee et leur procede de fabrication |
DK2316456T3 (en) | 2003-04-29 | 2017-09-11 | Orexigen Therapeutics Inc | Compositions for affecting weight loss comprising an opioid antagonist and bupropion |
US8569277B2 (en) * | 2004-08-11 | 2013-10-29 | Palo Alto Investors | Methods of treating a subject for a condition |
ES2377526T3 (es) * | 2005-01-10 | 2012-03-28 | Cortendo Ab (Publ) | 2S,4R ketoconazol para el tratamiento de la diabetes, el síndrome metabólico y otras afecciones |
EP1948238B1 (de) * | 2005-11-10 | 2013-08-28 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Zusammensetzungen und Verfahren zur Behandlung von Sucht und anderen neuropsychiatrischen Erkrankungen |
ES2402522T3 (es) | 2005-11-22 | 2013-05-06 | Orexigen Therapeutics, Inc. | Composiciones y procedimientos para aumentar la sensibilidad a la insulina |
AU2007204969A1 (en) * | 2006-01-10 | 2007-07-19 | Cortendo Invest Ab | Methods and compositions for treating prostate cancer |
CA2649720A1 (en) * | 2006-04-18 | 2007-10-25 | Tim Stewart | Methods and compositions for treating barth syndrome, cardiomyopathy, mitochondrial diseases and other conditions |
US8916195B2 (en) | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
EP1886695A1 (de) * | 2006-06-27 | 2008-02-13 | Speedel Experimenta AG | Pharmazeutische Kombinationen mit einem Aldosteron Synthasehemmer und Glucocorticoid Rezeptorantagonisten oder Cortisol Synthasehemmer oder Corticotropin Releasing Faktor Antagonisten |
ZA200902127B (en) * | 2006-10-02 | 2010-07-28 | Cortendo Invest Ab | Ketoconazole enantiomer in humans |
KR20170077291A (ko) | 2006-11-09 | 2017-07-05 | 오렉시젠 세러퓨틱스 인크. | 단위 용량 팩키지 |
JP5271918B2 (ja) * | 2007-01-16 | 2013-08-21 | アイピントゥル,エルエルシー | メタボリック症候群治療用の新規組成物 |
JP2011521973A (ja) | 2008-05-30 | 2011-07-28 | オレキシジェン・セラピューティクス・インコーポレーテッド | 内臓脂肪の状態を処置するための方法 |
CN102724878A (zh) | 2010-01-11 | 2012-10-10 | 奥雷西根治疗公司 | 在重度抑郁症患者中提供体重减轻疗法的方法 |
EP2582375A4 (de) * | 2010-06-16 | 2013-12-25 | Embera Neurotherapeutics Inc | Zusammensetzungen und verfahren zur behandlung von sucht, psychischen störungen und neurodegenerativen erkrankungen |
GB201102913D0 (en) * | 2011-02-18 | 2011-04-06 | Univ Birmingham | Novel therapeutic |
CN102204918A (zh) * | 2011-03-03 | 2011-10-05 | 厦门大学 | 一种PPARγ激动剂的类固醇化合物及其用途 |
LT3730132T (lt) | 2012-06-06 | 2022-08-25 | Nalpropion Pharmaceuticals Llc | Kompozicija, skirta panaudoti pacientų su didele širdies ir kraujagyslių ligų rizika antsvorio ir nutukimo gydymo būde |
US8969371B1 (en) | 2013-12-06 | 2015-03-03 | Orexigen Therapeutics, Inc. | Compositions and methods for weight loss in at risk patient populations |
CN106389368B (zh) * | 2015-07-29 | 2021-11-12 | 四川科瑞德制药股份有限公司 | 一种丙戊酸钠缓释制剂及其制备工艺和用途 |
AU2018230521B2 (en) | 2017-03-10 | 2022-02-03 | Embera Neurotherapeutics, Inc. | Pharmaceutical compositions and uses thereof |
WO2020074958A1 (en) | 2018-10-12 | 2020-04-16 | Strongbridge Dublin Limited | Levoketoconazole for treatment of congenital adrenal hyperplasia and primary aldosteronism |
AU2020239920A1 (en) * | 2019-03-18 | 2021-11-04 | Arnold L. Newman | Method of improving insulin sensitivity |
CN115372482B (zh) * | 2021-05-17 | 2024-06-18 | 上海交通大学医学院附属仁济医院 | 肠道菌群谱和代谢标志物在制备***诊断试剂盒中的应用 |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE8206744D0 (sv) * | 1982-11-26 | 1982-11-26 | Fluidcarbon International Ab | Preparat for kontrollerad avgivning av substanser |
JPH0759521B2 (ja) * | 1985-09-30 | 1995-06-28 | 藤沢薬品工業株式会社 | ゲル層形成型徐放性製剤 |
SE8601624D0 (sv) * | 1986-04-11 | 1986-04-11 | Haessle Ab | New pharmaceutical preparations |
US5371109A (en) * | 1986-07-01 | 1994-12-06 | Drilletten Ab | Controlled release composition for a biologically active material dissolved or dispersed in an L2-phase |
US5468755A (en) * | 1988-05-10 | 1995-11-21 | The Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Therapeutic process for the treatment of the pathologies of Type II diabetes |
US5476852A (en) * | 1989-05-03 | 1995-12-19 | Janssen Pharmaceutica N.V. | Method of topically treating acne vulgaris, hyperkeratotic dermatoses, and photo-aging of the skin |
JP2918331B2 (ja) * | 1989-08-25 | 1999-07-12 | バイオグラン ラボラトリーズ リミテッド | 薬剤混合物、およびそれを使用するための装置 |
US5143934A (en) * | 1990-11-21 | 1992-09-01 | A/S Dumex (Dumex Ltd.) | Method and composition for controlled delivery of biologically active agents |
US5262164A (en) * | 1989-11-17 | 1993-11-16 | The Procter & Gamble Company | Sustained release compositions for treating periodontal disease |
US5230895A (en) * | 1990-05-01 | 1993-07-27 | Copley Pharmaceutical Inc. | Sustained released delivery system for use in the periodontal pocket |
US5252564A (en) * | 1991-03-29 | 1993-10-12 | The United States Of America As Represented By The Secretary Of Agriculture | Method to decrease cortisol secretion by feeding melengesterol acetate |
WO1994014447A1 (en) * | 1992-12-22 | 1994-07-07 | Sepracor, Inc. | Methods and compositions of (-) ketoconazole for treating fungal yeast and dermatophyte infections |
US5543150A (en) * | 1993-09-15 | 1996-08-06 | Columbia Laboratories, Inc. | Method of progesterone delivery and affect thereof |
GB9405304D0 (en) * | 1994-03-16 | 1994-04-27 | Scherer Ltd R P | Delivery systems for hydrophobic drugs |
ATE180971T1 (de) * | 1994-03-30 | 1999-06-15 | Gs Dev Ab | Verwendung von fettsäureester als bioklebstoffe |
SE518578C2 (sv) * | 1994-06-15 | 2002-10-29 | Gs Dev Ab | Lipidbaserad komposition |
WO1996003124A1 (en) * | 1994-07-27 | 1996-02-08 | California Institute Of Technology | Dynemicin analogs |
WO1996004912A1 (en) * | 1994-08-09 | 1996-02-22 | Metabolic Syndrome I Gbg Ab | Use of ketoconazole and related substances in medicaments for treatment of type ii diabetes |
GB9522403D0 (en) * | 1995-11-01 | 1996-01-03 | Hoechst Roussel Ltd | Intravaginal drug delivery device |
US5756569A (en) * | 1996-12-19 | 1998-05-26 | Carver; Bobby Carroll | Use of alkyl 3-alkoxypropionates as coalescing agents in aqueous coating compositions |
GB9617001D0 (en) * | 1996-08-13 | 1996-09-25 | Tillotts Pharma Ag | Oral composition |
SE9700642D0 (sv) * | 1997-02-24 | 1997-02-24 | Kronvall Stefan Med Ab | Medel och sätt för förebyggande och behandling av det metabola syndromet |
EP0872229A1 (de) * | 1997-04-14 | 1998-10-21 | Janssen Pharmaceutica N.V. | Mittel enthaltend ein Fungizid und ein Phospholipid |
SE9902597D0 (sv) * | 1999-07-06 | 1999-07-06 | Astra Ab | New use |
US6428809B1 (en) * | 1999-08-18 | 2002-08-06 | Microdose Technologies, Inc. | Metering and packaging of controlled release medication |
-
2000
- 2000-01-21 GB GBGB0001449.8A patent/GB0001449D0/en not_active Ceased
-
2001
- 2001-01-19 AU AU26934/01A patent/AU783281B2/en not_active Ceased
- 2001-01-19 US US10/169,891 patent/US20030190357A1/en not_active Abandoned
- 2001-01-19 PL PL01363218A patent/PL363218A1/xx not_active Application Discontinuation
- 2001-01-19 MX MXPA02007117A patent/MXPA02007117A/es unknown
- 2001-01-19 NZ NZ519993A patent/NZ519993A/en unknown
- 2001-01-19 WO PCT/GB2001/000201 patent/WO2001052833A1/en not_active Application Discontinuation
- 2001-01-19 AT AT01901275T patent/ATE314062T1/de not_active IP Right Cessation
- 2001-01-19 CZ CZ20022439A patent/CZ20022439A3/cs unknown
- 2001-01-19 DE DE60116256T patent/DE60116256T2/de not_active Expired - Fee Related
- 2001-01-19 RU RU2002119568/15A patent/RU2002119568A/ru not_active Application Discontinuation
- 2001-01-19 KR KR1020027009347A patent/KR20020069262A/ko not_active Application Discontinuation
- 2001-01-19 CA CA002397065A patent/CA2397065A1/en not_active Abandoned
- 2001-01-19 EP EP01901275A patent/EP1251843B1/de not_active Expired - Lifetime
- 2001-01-19 CN CN01803904A patent/CN1416340A/zh active Pending
- 2001-01-19 JP JP2001552881A patent/JP2003520788A/ja active Pending
- 2001-01-19 HU HU0204340A patent/HUP0204340A3/hu unknown
-
2002
- 2002-01-19 SK SK1048-2002A patent/SK10482002A3/sk not_active Application Discontinuation
- 2002-07-19 NO NO20023473A patent/NO20023473L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2001052833A8 (en) | 2001-10-11 |
US20030190357A1 (en) | 2003-10-09 |
DE60116256T2 (de) | 2006-09-14 |
DE60116256D1 (de) | 2006-02-02 |
NZ519993A (en) | 2006-07-28 |
WO2001052833A1 (en) | 2001-07-26 |
EP1251843A1 (de) | 2002-10-30 |
JP2003520788A (ja) | 2003-07-08 |
PL363218A1 (en) | 2004-11-15 |
AU783281B2 (en) | 2005-10-06 |
RU2002119568A (ru) | 2004-02-27 |
GB0001449D0 (en) | 2000-03-08 |
CN1416340A (zh) | 2003-05-07 |
SK10482002A3 (sk) | 2003-03-04 |
CA2397065A1 (en) | 2001-07-26 |
EP1251843B1 (de) | 2005-12-28 |
HUP0204340A3 (en) | 2005-04-28 |
HUP0204340A2 (en) | 2003-05-28 |
NO20023473L (no) | 2002-09-23 |
KR20020069262A (ko) | 2002-08-29 |
NO20023473D0 (no) | 2002-07-19 |
CZ20022439A3 (cs) | 2003-02-12 |
MXPA02007117A (es) | 2004-08-23 |
AU2693401A (en) | 2001-07-31 |
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