ATE309228T1 - Isoxazolderivate - Google Patents
IsoxazolderivateInfo
- Publication number
- ATE309228T1 ATE309228T1 AT98914071T AT98914071T ATE309228T1 AT E309228 T1 ATE309228 T1 AT E309228T1 AT 98914071 T AT98914071 T AT 98914071T AT 98914071 T AT98914071 T AT 98914071T AT E309228 T1 ATE309228 T1 AT E309228T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- formula
- represented
- solid line
- single bond
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physical Education & Sports Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP11887197 | 1997-04-21 | ||
| JP36715497 | 1997-12-24 | ||
| PCT/JP1998/001770 WO1998047880A1 (en) | 1997-04-21 | 1998-04-17 | Isoxazole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE309228T1 true ATE309228T1 (de) | 2005-11-15 |
Family
ID=26456721
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98914071T ATE309228T1 (de) | 1997-04-21 | 1998-04-17 | Isoxazolderivate |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0979226B1 (de) |
| KR (1) | KR100512087B1 (de) |
| CN (1) | CN1138764C (de) |
| AT (1) | ATE309228T1 (de) |
| AU (1) | AU733091B2 (de) |
| CA (1) | CA2235298C (de) |
| DE (1) | DE69832270T2 (de) |
| DK (1) | DK0979226T3 (de) |
| ES (1) | ES2248894T3 (de) |
| ID (1) | ID22897A (de) |
| NZ (1) | NZ330244A (de) |
| RU (1) | RU2196770C2 (de) |
| TW (1) | TW442476B (de) |
| WO (1) | WO1998047880A1 (de) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5852300A (en) * | 1999-07-15 | 2001-02-05 | Sumitomo Pharmaceuticals Company, Limited | Heteroaromatic ring compounds |
| WO2001047895A1 (fr) * | 1999-12-28 | 2001-07-05 | Sumitomo Pharmaceuticals Company, Limited | Nouveaux composes comprenant des cycles heteroaromatiques a cinq chainons |
| DE60222643T2 (de) * | 2001-03-27 | 2008-07-17 | Dainippon Sumitomo Pharma Co., Ltd. | Kristallines isoxazol-derivat und medizinisches präparat daraus |
| AU2003207055A1 (en) * | 2002-02-12 | 2003-09-04 | Sumitomo Pharmaceuticals Co., Ltd. | Novel drugs for external use |
| ITMI20040019A1 (it) * | 2004-01-12 | 2004-04-12 | Univ Bari | Derivati isossazolici e loro impiego come inibitori della ciclossigenasi |
| DE102004008141A1 (de) * | 2004-02-19 | 2005-09-01 | Abbott Gmbh & Co. Kg | Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren |
| KR20070085618A (ko) * | 2004-11-02 | 2007-08-27 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 자가 면역 질환을 치료하기 위한 병용약 |
| US7989450B2 (en) | 2008-01-11 | 2011-08-02 | Universita' Degli Studi Di Bari | Functionalized diarylisoxazoles inhibitors of ciclooxygenase |
| EA027351B1 (ru) * | 2011-01-28 | 2017-07-31 | 4-Эс-Си Дискавери Гмбх | Ингибирование il17 и ifn-гамма для лечения аутоиммунного воспаления |
| DE102014201651A1 (de) | 2014-01-30 | 2015-07-30 | Georg-August-Universität Göttingen Stiftung Öffentlichen Rechts, Universitätsmedizin | Isoxazolderivate zur Verwendung bei der Behandlung und/oder Prophylaxe von Herzerkrankungen |
| CN111269149B (zh) * | 2020-04-08 | 2022-04-15 | 南京优氟医药科技有限公司 | 一种5-(3,3-二甲基胍基)-2-氧代戊酸的生产工艺 |
| CN114478350B (zh) * | 2022-01-25 | 2023-08-11 | 苏州大学 | 一种c3-烷基化吲哚的制备方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2068418A1 (en) * | 1969-10-27 | 1971-08-27 | Innothera Lab Sa | 2-substd-5-amino isoxazole derivs |
| US3720685A (en) * | 1970-07-15 | 1973-03-13 | Squibb & Sons Inc | 3-amino-5-benzyl-1,2,4-oxadiazoles |
| GB1338169A (en) * | 1971-03-09 | 1973-11-21 | Smith Kline French Lab | Ureas thioureas and guanidines |
| DE2341507A1 (de) * | 1973-08-16 | 1975-02-27 | Thomae Gmbh Dr K | Neue biphenylderivate und verfahren zur herstellung |
| JPS54144347A (en) * | 1978-05-02 | 1979-11-10 | Nikken Kagaku Kk | 3-(2-fluoro-4-biphenylyl)-2-butanone |
| HU180567B (en) * | 1980-03-19 | 1983-03-28 | Egyt Gyogyszervegyeszeti Gyar | Method for producing derivatives of isooxazole |
| JPS58150576A (ja) * | 1982-03-03 | 1983-09-07 | Sumitomo Chem Co Ltd | 新規な１，２，４−オキサジアゾ−ル誘導体 |
| US4680300A (en) * | 1985-01-10 | 1987-07-14 | Syntex (U.S.A.) Inc. | Anti-inflammatory guanidines |
| US4914112A (en) * | 1986-06-03 | 1990-04-03 | Sumitomo Pharmaceuticals Company, Limited | Aminoazole derivatives and their production and use |
| JP2719742B2 (ja) * | 1991-04-30 | 1998-02-25 | 株式会社大塚製薬工場 | フェニルチアゾール誘導体 |
-
1998
- 1998-04-17 CN CNB98804398XA patent/CN1138764C/zh not_active Expired - Fee Related
- 1998-04-17 ES ES98914071T patent/ES2248894T3/es not_active Expired - Lifetime
- 1998-04-17 ID IDW991245A patent/ID22897A/id unknown
- 1998-04-17 AU AU61934/98A patent/AU733091B2/en not_active Ceased
- 1998-04-17 EP EP98914071A patent/EP0979226B1/de not_active Expired - Lifetime
- 1998-04-17 DK DK98914071T patent/DK0979226T3/da active
- 1998-04-17 DE DE69832270T patent/DE69832270T2/de not_active Expired - Lifetime
- 1998-04-17 KR KR10-1999-7009591A patent/KR100512087B1/ko not_active IP Right Cessation
- 1998-04-17 AT AT98914071T patent/ATE309228T1/de active
- 1998-04-17 WO PCT/JP1998/001770 patent/WO1998047880A1/en active IP Right Grant
- 1998-04-20 RU RU98107337/04A patent/RU2196770C2/ru not_active IP Right Cessation
- 1998-04-20 CA CA002235298A patent/CA2235298C/en not_active Expired - Fee Related
- 1998-04-20 TW TW087106014A patent/TW442476B/zh not_active IP Right Cessation
- 1998-04-21 NZ NZ330244A patent/NZ330244A/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU6193498A (en) | 1998-10-22 |
| WO1998047880A1 (en) | 1998-10-29 |
| DK0979226T3 (da) | 2006-03-06 |
| CN1252794A (zh) | 2000-05-10 |
| ID22897A (id) | 1999-12-16 |
| ES2248894T3 (es) | 2006-03-16 |
| KR20010006501A (ko) | 2001-01-26 |
| EP0979226B1 (de) | 2005-11-09 |
| CN1138764C (zh) | 2004-02-18 |
| TW442476B (en) | 2001-06-23 |
| CA2235298A1 (en) | 1998-10-21 |
| RU2196770C2 (ru) | 2003-01-20 |
| CA2235298C (en) | 2008-05-13 |
| EP0979226A1 (de) | 2000-02-16 |
| DE69832270D1 (de) | 2005-12-15 |
| AU733091B2 (en) | 2001-05-03 |
| KR100512087B1 (ko) | 2005-09-05 |
| DE69832270T2 (de) | 2006-07-13 |
| NZ330244A (en) | 2000-01-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEIH | Change in the person of patent owner |