ATE295166T1 - Aktivatoren der kalium-kanäle - Google Patents
Aktivatoren der kalium-kanäleInfo
- Publication number
- ATE295166T1 ATE295166T1 AT99900312T AT99900312T ATE295166T1 AT E295166 T1 ATE295166 T1 AT E295166T1 AT 99900312 T AT99900312 T AT 99900312T AT 99900312 T AT99900312 T AT 99900312T AT E295166 T1 ATE295166 T1 AT E295166T1
- Authority
- AT
- Austria
- Prior art keywords
- substituted
- amino
- aryl
- pharmaceutical composition
- alkyl
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/40—2,5-Pyrrolidine-diones
- C07D207/416—2,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Bakery Products And Manufacturing Methods Therefor (AREA)
- Detergent Compositions (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP561398 | 1998-01-14 | ||
JP5088898 | 1998-03-03 | ||
PCT/JP1999/000103 WO1999036068A1 (fr) | 1998-01-14 | 1999-01-13 | Activateurs des canaux de potassium |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE295166T1 true ATE295166T1 (de) | 2005-05-15 |
Family
ID=26339581
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99900312T ATE295166T1 (de) | 1998-01-14 | 1999-01-13 | Aktivatoren der kalium-kanäle |
Country Status (10)
Country | Link |
---|---|
US (1) | US6353016B1 (de) |
EP (1) | EP1057485B1 (de) |
KR (1) | KR20010034114A (de) |
CN (1) | CN1162151C (de) |
AT (1) | ATE295166T1 (de) |
AU (1) | AU1890299A (de) |
CA (1) | CA2316853A1 (de) |
DE (1) | DE69925250T2 (de) |
RU (1) | RU2204390C2 (de) |
WO (1) | WO1999036068A1 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030019326A (ko) * | 2000-03-21 | 2003-03-06 | 니뽄 신야쿠 가부시키가이샤 | 방출 제어형 경구 투여 제제 |
CA2415815A1 (en) * | 2000-07-06 | 2002-01-17 | Nigel H. Greig | Tetrahydrobenzothiazole analogues as neuroprotective agents |
TWI239952B (en) * | 2001-03-14 | 2005-09-21 | Nippon Shinyaku Co Ltd | Stable crystals of pyrrole compound |
ATE415959T1 (de) * | 2003-09-04 | 2008-12-15 | Neurosearch As | Herg1-kanal-öffner zur behandlung von herzarrythmien |
US8026237B2 (en) * | 2004-07-30 | 2011-09-27 | Exelixis, Inc. | Pyrrole derivatives as pharmaceutical agents |
US8278466B2 (en) | 2008-04-28 | 2012-10-02 | Janssen Pharmaceutica Nv | Benzocycloheptane and benzoxepine derivatives |
GB201107176D0 (en) * | 2011-04-28 | 2011-06-15 | Cxr Biosciences Ltd | Pyrrolnitrin derivatives |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0548680T3 (da) * | 1991-12-26 | 1998-09-23 | Mitsubishi Chem Corp | Beta-oxo-beta-benzenpropanthioamidderivater |
JP3439249B2 (ja) * | 1993-11-18 | 2003-08-25 | 三和生薬株式会社 | 新規なピロール型化合物及び発毛・育毛促進剤 |
BR9608502A (pt) * | 1995-06-07 | 1999-07-06 | Nippon Shinyaku Co Ltd | Derivado da pirrola e composição medicinal |
AU702887B2 (en) * | 1995-10-31 | 1999-03-11 | Merck & Co., Inc. | Substituted pyridyl pyrroles, compositions containing such compounds and methods of use |
US6417202B1 (en) * | 1996-07-11 | 2002-07-09 | Pfizer Inc. | Pyridylpyrrole compounds useful as interleukin-and TNF antagonists |
WO1999061016A1 (en) * | 1998-05-27 | 1999-12-02 | Nippon Shinyaku Co., Ltd. | Cyclooxygenase-2 inhibitors |
-
1999
- 1999-01-13 WO PCT/JP1999/000103 patent/WO1999036068A1/ja active IP Right Grant
- 1999-01-13 AU AU18902/99A patent/AU1890299A/en not_active Abandoned
- 1999-01-13 CN CNB998021067A patent/CN1162151C/zh not_active Expired - Fee Related
- 1999-01-13 DE DE69925250T patent/DE69925250T2/de not_active Expired - Fee Related
- 1999-01-13 CA CA002316853A patent/CA2316853A1/en not_active Abandoned
- 1999-01-13 US US09/582,743 patent/US6353016B1/en not_active Expired - Fee Related
- 1999-01-13 RU RU2000121069/14A patent/RU2204390C2/ru not_active IP Right Cessation
- 1999-01-13 EP EP99900312A patent/EP1057485B1/de not_active Expired - Lifetime
- 1999-01-13 KR KR1020007007727A patent/KR20010034114A/ko not_active Application Discontinuation
- 1999-01-13 AT AT99900312T patent/ATE295166T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1999036068A1 (fr) | 1999-07-22 |
CN1162151C (zh) | 2004-08-18 |
EP1057485B1 (de) | 2005-05-11 |
KR20010034114A (ko) | 2001-04-25 |
CA2316853A1 (en) | 1999-07-22 |
CN1288377A (zh) | 2001-03-21 |
EP1057485A4 (de) | 2001-05-09 |
AU1890299A (en) | 1999-08-02 |
DE69925250D1 (de) | 2005-06-16 |
EP1057485A1 (de) | 2000-12-06 |
US6353016B1 (en) | 2002-03-05 |
DE69925250T2 (de) | 2006-02-23 |
RU2204390C2 (ru) | 2003-05-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |