ATE284382T1 - Hydroxamsäurederivat als inhibitor der produktion von löslichem menschlichem cd23 - Google Patents

Hydroxamsäurederivat als inhibitor der produktion von löslichem menschlichem cd23

Info

Publication number
ATE284382T1
ATE284382T1 AT00975954T AT00975954T ATE284382T1 AT E284382 T1 ATE284382 T1 AT E284382T1 AT 00975954 T AT00975954 T AT 00975954T AT 00975954 T AT00975954 T AT 00975954T AT E284382 T1 ATE284382 T1 AT E284382T1
Authority
AT
Austria
Prior art keywords
inhibitor
production
acid derivative
hydroxamic acid
soluble human
Prior art date
Application number
AT00975954T
Other languages
English (en)
Inventor
Andrew S Faller
John Gerard Ward
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Application granted granted Critical
Publication of ATE284382T1 publication Critical patent/ATE284382T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/22Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
AT00975954T 1999-10-27 2000-10-25 Hydroxamsäurederivat als inhibitor der produktion von löslichem menschlichem cd23 ATE284382T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9925470.8A GB9925470D0 (en) 1999-10-27 1999-10-27 Novel compounds
PCT/EP2000/010649 WO2001030747A1 (en) 1999-10-27 2000-10-25 Hydroxamic acid derivative as inhibitor of the formation of soluble human cd23

Publications (1)

Publication Number Publication Date
ATE284382T1 true ATE284382T1 (de) 2004-12-15

Family

ID=10863507

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00975954T ATE284382T1 (de) 1999-10-27 2000-10-25 Hydroxamsäurederivat als inhibitor der produktion von löslichem menschlichem cd23

Country Status (32)

Country Link
US (2) US6673965B1 (de)
EP (1) EP1224164B1 (de)
JP (1) JP3922431B2 (de)
KR (1) KR20020044578A (de)
CN (1) CN1182107C (de)
AR (1) AR026244A1 (de)
AT (1) ATE284382T1 (de)
AU (1) AU766072B2 (de)
BR (1) BR0015082A (de)
CA (1) CA2389319A1 (de)
CO (1) CO5261576A1 (de)
CZ (1) CZ20021424A3 (de)
DE (1) DE60016622T2 (de)
DK (1) DK1224164T3 (de)
ES (1) ES2233474T3 (de)
GB (1) GB9925470D0 (de)
GC (1) GC0000142A (de)
HK (1) HK1049146A1 (de)
HU (1) HUP0203270A3 (de)
IL (1) IL149364A0 (de)
MX (1) MXPA02004228A (de)
MY (1) MY133601A (de)
NO (1) NO20021965L (de)
NZ (1) NZ518566A (de)
PE (1) PE20010898A1 (de)
PL (1) PL356524A1 (de)
PT (1) PT1224164E (de)
SI (1) SI1224164T1 (de)
TW (1) TW561141B (de)
UY (1) UY26416A1 (de)
WO (1) WO2001030747A1 (de)
ZA (1) ZA200203255B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2334636A2 (de) * 2008-09-19 2011-06-22 Pfizer Inc. Als antibakterielle mittel geeignete hydroxaminsäurederivate
WO2011068853A2 (en) 2009-12-01 2011-06-09 Boston Medical Center Corporation TREATMENT OF IgE-MEDIATED DISEASE
CA2782453C (en) 2009-12-16 2015-11-24 Matthew Frank Brown N-linked hydroxamic acid derivatives useful as antibacterial agents
MX341977B (es) 2011-03-07 2016-09-07 Pfizer Derivados de fluoro-piridinona utiles como agentes antibacterianos.
CA2830866A1 (en) 2011-04-08 2012-10-11 Pfizer Inc. Imidazole, pyrazole, and triazole derivatives useful as antibacterial agents
CA2830920C (en) 2011-04-08 2015-07-14 Pfizer Inc. Isoxazole derivatives useful as antibacterial agents
EP2525213A1 (de) * 2011-05-16 2012-11-21 Renishaw plc Spektroskopievorrichtung und Verfahren zur Bestimmung der in einer Probe vorkommenden Komponenten

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9513331D0 (en) 1995-06-30 1995-09-06 British Biotech Pharm Matrix metalloproteinase inhibitors
GB9813451D0 (en) * 1998-06-22 1998-08-19 Smithkline Beecham Plc Novel compounds

Also Published As

Publication number Publication date
DE60016622D1 (de) 2005-01-13
NO20021965L (no) 2002-06-13
MY133601A (en) 2007-11-30
MXPA02004228A (es) 2002-10-17
EP1224164A1 (de) 2002-07-24
WO2001030747A1 (en) 2001-05-03
SI1224164T1 (en) 2005-06-30
GB9925470D0 (en) 1999-12-29
BR0015082A (pt) 2003-04-15
NO20021965D0 (no) 2002-04-25
IL149364A0 (en) 2002-11-10
DE60016622T2 (de) 2005-11-03
PL356524A1 (en) 2004-06-28
UY26416A1 (es) 2001-05-31
HUP0203270A3 (en) 2003-11-28
CZ20021424A3 (cs) 2002-09-11
AU1389501A (en) 2001-05-08
GC0000142A (en) 2005-06-29
CO5261576A1 (es) 2003-03-31
CN1182107C (zh) 2004-12-29
PT1224164E (pt) 2005-04-29
US6673965B1 (en) 2004-01-06
JP3922431B2 (ja) 2007-05-30
ZA200203255B (en) 2003-03-20
NZ518566A (en) 2004-02-27
US20040077727A1 (en) 2004-04-22
PE20010898A1 (es) 2001-10-13
CN1411436A (zh) 2003-04-16
AR026244A1 (es) 2003-02-05
CA2389319A1 (en) 2001-05-03
HK1049146A1 (en) 2003-05-02
ES2233474T3 (es) 2005-06-16
AU766072B2 (en) 2003-10-09
HUP0203270A2 (hu) 2003-02-28
TW561141B (en) 2003-11-11
EP1224164B1 (de) 2004-12-08
KR20020044578A (ko) 2002-06-15
DK1224164T3 (da) 2005-03-29
JP2003512450A (ja) 2003-04-02

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