ATE252158T1 - Nicht-nukleotid verknüpfende reagentien - Google Patents

Nicht-nukleotid verknüpfende reagentien

Info

Publication number
ATE252158T1
ATE252158T1 AT97926780T AT97926780T ATE252158T1 AT E252158 T1 ATE252158 T1 AT E252158T1 AT 97926780 T AT97926780 T AT 97926780T AT 97926780 T AT97926780 T AT 97926780T AT E252158 T1 ATE252158 T1 AT E252158T1
Authority
AT
Austria
Prior art keywords
pct
reagents
nucleotide
linking reagents
nucleotide linking
Prior art date
Application number
AT97926780T
Other languages
English (en)
Inventor
Su George Sheng-Hui
Rajkumar Siva Iyer
Sunil K Aggarwal
Krishan L Kalra
Original Assignee
Biogenex Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogenex Lab filed Critical Biogenex Lab
Application granted granted Critical
Publication of ATE252158T1 publication Critical patent/ATE252158T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/22—Amides of acids of phosphorus
    • C07F9/24—Esteramides
    • C07F9/2404—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic
    • C07F9/2416—Esteramides the ester moiety containing a substituent or a structure which is considered as characteristic of cycloaliphatic alcohols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT97926780T 1996-05-15 1997-05-15 Nicht-nukleotid verknüpfende reagentien ATE252158T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US64782096A 1996-05-15 1996-05-15
PCT/US1997/009094 WO1997043451A1 (en) 1996-05-15 1997-05-15 Non-nucleotide linking reagents

Publications (1)

Publication Number Publication Date
ATE252158T1 true ATE252158T1 (de) 2003-11-15

Family

ID=24598396

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97926780T ATE252158T1 (de) 1996-05-15 1997-05-15 Nicht-nukleotid verknüpfende reagentien

Country Status (8)

Country Link
US (1) US6130323A (de)
EP (1) EP0954606B1 (de)
JP (1) JP2001509784A (de)
AT (1) ATE252158T1 (de)
AU (1) AU733647B2 (de)
CA (1) CA2253969A1 (de)
DE (1) DE69725611T2 (de)
WO (1) WO1997043451A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE327508T1 (de) * 1998-11-06 2006-06-15 Mitsubishi Kagaku Iatron Inc Neue komplexe, die vernetztes avidin enthalten, verfahren zur herstellung und analyseverfahren, das diese verwendet
US6635427B2 (en) 2000-08-11 2003-10-21 University Of Utah Research Foundation Single-labeled oligonucleotide probes for homogeneous nucleic acid sequence analysis
US7560231B2 (en) 2002-12-20 2009-07-14 Roche Molecular Systems, Inc. Mannitol and glucitol derivatives
WO2004089295A2 (en) * 2003-04-01 2004-10-21 Chromagen, Inc. Homogeneous and heterogeneous assay methods using nucleation centers and novel covalent chemistries for the rapid measurement of phosphorylation and de-phosphorylation
CA2463719A1 (en) * 2003-04-05 2004-10-05 F. Hoffmann-La Roche Ag Nucleotide analogs with six membered rings
EP1502958A1 (de) * 2003-08-01 2005-02-02 Roche Diagnostics GmbH Neues Format zur Detektion von Heissstart- und Echtzeit-Polymerasekettenreaktion
EP1700922B1 (de) 2005-03-10 2016-08-24 Roche Diagnostics GmbH 3-Substituierte 5-Nitroindolderivate und diese enthaltende markierte Oligonukleotidsonden
ES2332139T3 (es) 2005-11-23 2010-01-27 F. Hoffmann-La Roche Ag Polinucleotidos con mimetico de fosfato.
US7759470B2 (en) 2006-02-20 2010-07-20 Roche Diagnostics Operations, Inc. Labeling reagent
EP2156370B1 (de) 2007-05-14 2011-10-12 Historx, Inc. Abteilungsauftrennung durch pixelcharakterisierung unter verwendung von bilddatenclusterung
WO2008156669A1 (en) 2007-06-15 2008-12-24 Historx, Inc. Method and system for standardizing microscope instruments
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
CA2596204C (en) 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
US7978258B2 (en) 2007-08-31 2011-07-12 Historx, Inc. Automatic exposure time selection for imaging tissue
CN102165489B (zh) 2008-09-16 2015-11-25 赫斯托克斯公司 生物标志物表达的可再现量化
US20120302737A1 (en) 2009-09-16 2012-11-29 Genentech, Inc. Coiled coil and/or tether containing protein complexes and uses thereof
TW201138821A (en) 2010-03-26 2011-11-16 Roche Glycart Ag Bispecific antibodies
SG191153A1 (en) 2010-12-23 2013-07-31 Hoffmann La Roche Polypeptide-polynucleotide-complex and its use in targeted effector moiety delivery
EP2659269B1 (de) 2010-12-23 2016-10-26 Roche Diagniostics GmbH Erkennung von posttranslational modifiziertem polypeptid durch ein bivalentes bindungsmolekül
CN104105711B (zh) 2012-02-10 2018-11-30 弗·哈夫曼-拉罗切有限公司 单链抗体及其他异多聚体
CN104395339A (zh) 2012-06-27 2015-03-04 弗·哈夫曼-拉罗切有限公司 用于选择并产生含有至少两种不同结合实体的定制高度选择性和多特异性靶向实体的方法及其用途
CA2871882A1 (en) 2012-06-27 2014-01-03 F. Hoffmann-La Roche Ag Method for making antibody fc-region conjugates comprising at least one binding entity that specifically binds to a target and uses thereof
ES2764111T3 (es) 2014-12-03 2020-06-02 Hoffmann La Roche Anticuerpos multiespecíficos
IL291323B2 (en) * 2016-07-15 2023-09-01 Am Chemicals Llc Solid non-nucleoside supports and phosphoramidite building blocks for oligonucleotide synthesis
CN108219513B (zh) * 2018-03-14 2019-11-08 青岛科技大学 一种羧基荧光素的制备方法

Also Published As

Publication number Publication date
WO1997043451A1 (en) 1997-11-20
JP2001509784A (ja) 2001-07-24
EP0954606A1 (de) 1999-11-10
DE69725611D1 (de) 2003-11-20
AU3146597A (en) 1997-12-05
AU733647B2 (en) 2001-05-17
US6130323A (en) 2000-10-10
DE69725611T2 (de) 2004-07-29
CA2253969A1 (en) 1997-11-20
EP0954606A4 (de) 1999-12-22
EP0954606B1 (de) 2003-10-15

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