ATE248169T1 - 2-aryl-8-oxodihydropurin-derivate, ihre herstellung, ihre verwendung als medikamentenkomponente und deren intermediate - Google Patents
2-aryl-8-oxodihydropurin-derivate, ihre herstellung, ihre verwendung als medikamentenkomponente und deren intermediateInfo
- Publication number
- ATE248169T1 ATE248169T1 AT98955937T AT98955937T ATE248169T1 AT E248169 T1 ATE248169 T1 AT E248169T1 AT 98955937 T AT98955937 T AT 98955937T AT 98955937 T AT98955937 T AT 98955937T AT E248169 T1 ATE248169 T1 AT E248169T1
- Authority
- AT
- Austria
- Prior art keywords
- intermediates
- aryl
- production
- medication components
- oxodihydropurine derivatives
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000000543 intermediate Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP35000097 | 1997-12-03 | ||
PCT/JP1998/005320 WO1999028320A1 (fr) | 1997-12-03 | 1998-11-26 | Derives de 2-aryl-8-oxodihydropurine, procede de production de ces derives, compositions medicales contenant ces derives, et intermediaires de ces derives |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE248169T1 true ATE248169T1 (de) | 2003-09-15 |
Family
ID=18407561
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98955937T ATE248169T1 (de) | 1997-12-03 | 1998-11-26 | 2-aryl-8-oxodihydropurin-derivate, ihre herstellung, ihre verwendung als medikamentenkomponente und deren intermediate |
Country Status (27)
Country | Link |
---|---|
US (1) | US6372740B1 (de) |
EP (1) | EP1036794B1 (de) |
JP (1) | JP3815966B2 (de) |
KR (1) | KR100494347B1 (de) |
CN (1) | CN1146566C (de) |
AR (1) | AR017796A1 (de) |
AT (1) | ATE248169T1 (de) |
AU (1) | AU744014B2 (de) |
BR (1) | BR9815140A (de) |
CA (1) | CA2312885C (de) |
DE (1) | DE69817611T2 (de) |
DK (1) | DK1036794T3 (de) |
ES (1) | ES2205574T3 (de) |
HK (1) | HK1028769A1 (de) |
HU (1) | HUP0004422A3 (de) |
ID (1) | ID24929A (de) |
IL (1) | IL135920A0 (de) |
NO (1) | NO20002835L (de) |
NZ (1) | NZ504457A (de) |
PL (1) | PL191489B1 (de) |
PT (1) | PT1036794E (de) |
RU (1) | RU2223272C2 (de) |
SK (1) | SK285703B6 (de) |
TR (1) | TR200001600T2 (de) |
TW (1) | TW502034B (de) |
WO (1) | WO1999028320A1 (de) |
ZA (1) | ZA9810490B (de) |
Families Citing this family (50)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003146987A (ja) * | 1999-05-31 | 2003-05-21 | Dainippon Pharmaceut Co Ltd | 2−アリールプリン−9−アセトアミド誘導体 |
GB9913932D0 (en) * | 1999-06-15 | 1999-08-18 | Pfizer Ltd | Purine derivatives |
KR20020028232A (ko) * | 1999-09-27 | 2002-04-16 | 우에노 도시오 | 피리미딘 유도체 화합물, 그 제조 방법 및 그 화합물을유효성분으로 하는 의약 |
KR100829297B1 (ko) | 2000-07-31 | 2008-05-13 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 2-아릴-8-옥소디히드로푸린 유도체를 유효성분으로 하는치매증 치료제 |
CN1894222A (zh) * | 2003-08-05 | 2007-01-10 | 沃泰克斯药物股份有限公司 | 作为电压门控离子通道抑制剂的稠合嘧啶化合物 |
AU2005214258A1 (en) * | 2004-02-23 | 2005-09-01 | Dainippon Sumitomo Pharma Co., Ltd. | Novel heterocyclic compound |
WO2005115399A2 (en) * | 2004-04-16 | 2005-12-08 | Neurogen Corporation | Imidazopyrazines, imidazopyridines, ans imidazopyrimidines as crf1 receptor ligands |
FR2870239B1 (fr) * | 2004-05-11 | 2006-06-16 | Sanofi Synthelabo | Derives de carbamate de 2h- ou 3h-benzo[e]indazol-1-yle, leur preparation et leur application en therapeutique. |
MX2007012393A (es) * | 2005-04-05 | 2008-02-22 | Pharmacopeia Inc | Derivados de purina e imidazopiridina para la inmunosupresion. |
US7884109B2 (en) * | 2005-04-05 | 2011-02-08 | Wyeth Llc | Purine and imidazopyridine derivatives for immunosuppression |
GB0507298D0 (en) | 2005-04-11 | 2005-05-18 | Novartis Ag | Organic compounds |
WO2007030438A2 (en) * | 2005-09-06 | 2007-03-15 | Pharmacopeia, Inc. | Aminopurine derivatives for treating neurodegenerative diseases |
US7989459B2 (en) * | 2006-02-17 | 2011-08-02 | Pharmacopeia, Llc | Purinones and 1H-imidazopyridinones as PKC-theta inhibitors |
US20090281075A1 (en) * | 2006-02-17 | 2009-11-12 | Pharmacopeia, Inc. | Isomeric purinones and 1h-imidazopyridinones as pkc-theta inhibitors |
WO2007104053A2 (en) * | 2006-03-09 | 2007-09-13 | Pharmacopeia, Inc. | 8-heteroarylpurine mnk2 inhibitors for treating metabolic disorders |
CL2007002867A1 (es) * | 2006-10-04 | 2008-06-27 | Pharmacopeia Inc | Compuestos derivados de 2-(bencimidazolil)purina, inhibidores de janus quinasa 3; composicion farmaceutica que los contiene; y su uso para tratar enfermedades autoinmune, inflamatorias, cardiovasculares, rechazo de implante, entre otras. |
US7902187B2 (en) * | 2006-10-04 | 2011-03-08 | Wyeth Llc | 6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression |
AR063142A1 (es) * | 2006-10-04 | 2008-12-30 | Pharmacopeia Inc | Derivados de 2-(bencimidazolil) purina y purinonas 6-sustituidas utiles como inmunosupresores,y composiciones farmaceuticas que los contienen. |
KR101504669B1 (ko) * | 2006-10-19 | 2015-03-20 | 시그날 파마소티칼 엘엘씨 | 헤테로아릴 화합물, 이들의 조성물 그리고 단백질 키나아제 억제제로서의 이들의 용도 |
US20080119496A1 (en) * | 2006-11-16 | 2008-05-22 | Pharmacopeia Drug Discovery, Inc. | 7-Substituted Purine Derivatives for Immunosuppression |
JP2009007273A (ja) * | 2007-06-27 | 2009-01-15 | Ajinomoto Co Inc | ジアミノピリミジン化合物の製造方法 |
US8110578B2 (en) | 2008-10-27 | 2012-02-07 | Signal Pharmaceuticals, Llc | Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway |
US8473571B2 (en) | 2009-01-08 | 2013-06-25 | Microsoft Corporation | Synchronizing presentation states between multiple applications |
JP5738766B2 (ja) * | 2009-09-09 | 2015-06-24 | 大日本住友製薬株式会社 | 8−オキソジヒドロプリン誘導体 |
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JP2014076947A (ja) * | 2011-02-03 | 2014-05-01 | Dainippon Sumitomo Pharma Co Ltd | 2−オキシ置換8−オキソジヒドロプリン誘導体 |
WO2012168697A1 (en) | 2011-06-06 | 2012-12-13 | Imperial Innovations Limited | Methods to predict binding affinity of tspo imaging agents to tspo |
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IN2014CN04037A (de) | 2011-12-02 | 2015-10-23 | Signal Pharm Llc | |
ES2742398T3 (es) | 2012-02-24 | 2020-02-14 | Signal Pharm Llc | Métodos para tratar el cáncer de pulmón no microcítico usando una terapia de combinación de inhibidores de TOR quinasa |
CN102675315B (zh) * | 2012-02-28 | 2015-04-01 | 中国人民解放军第四军医大学 | 含取代苯烷基的嘌呤类化合物和制备方法及应用 |
AU2013203714B2 (en) | 2012-10-18 | 2015-12-03 | Signal Pharmaceuticals, Llc | Inhibition of phosphorylation of PRAS40, GSK3-beta or P70S6K1 as a marker for TOR kinase inhibitory activity |
CA2897985A1 (en) | 2013-01-16 | 2014-07-24 | Signal Pharmaceuticals, Llc | Substituted pyrrolopyrimidine compounds, compositions thereof, and methods of treatment therewith |
SG10201708111YA (en) | 2013-04-17 | 2017-11-29 | Signal Pharm Llc | Combination therapy comprising a dihydropyrazino-pyrazine compound and an androgen receptor antagonist for treating prostate cancer |
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NZ730189A (en) | 2013-04-17 | 2018-09-28 | Signal Pharm Llc | Pharmaceutical formulations, processes, solid forms and methods of use relating to 1-ethyl-7-(2-methyl-6-(1h-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1h)-one |
JP2016516818A (ja) | 2013-04-17 | 2016-06-09 | シグナル ファーマシューティカルズ,エルエルシー | 癌を治療するためのtorキナーゼ阻害剤及びn−(3−(5−フルオロ−2−(4−(2−メトキシエトキシ)フェニルアミノ)ピリミジン−4−イルアミノ)フェニル)アクリルアミドを含む組合せ療法 |
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EP2986321A1 (de) | 2013-04-17 | 2016-02-24 | Signal Pharmaceuticals, LLC | Kombinationstherapie mit einem torkinaseinhibitor und einem cytidinanalogon zur behandlung von krebs |
WO2014172425A1 (en) | 2013-04-17 | 2014-10-23 | Signal Pharmaceuticals, Llc | Treatment of cancer with dihydropyrazino-pyrazines |
CN113831345A (zh) | 2013-05-29 | 2021-12-24 | 西格诺药品有限公司 | 二氢吡嗪并吡嗪化合物的药物组合物、其固体形式和它们的用途 |
US9718824B2 (en) | 2014-04-16 | 2017-08-01 | Signal Pharmaceuticals, Llc | Solid forms comprising 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one, and a coformer, compositions and methods of use thereof |
EP3131552B1 (de) | 2014-04-16 | 2020-07-15 | Signal Pharmaceuticals, LLC | Verfahren zur behandlung von krebs anhand einer tor-kinasehemmerkombinationstherapie |
JP2017511367A (ja) | 2014-04-16 | 2017-04-20 | シグナル ファーマシューティカルズ,エルエルシー | 1−エチル−7−(2−メチル−6−(1H−1,2,4−トリアゾール−3−イル)ピリジン−3−イル)−3,4−ジヒドロピラジノ[2,3−b]ピラジン−2(1H)−オン及び共形成物を含む固体形態、その組成物及び使用方法 |
NZ714742A (en) | 2014-04-16 | 2017-04-28 | Signal Pharm Llc | Solid forms of 1-ethyl-7-(2-methyl-6-(1h-1,2,4-triazol-3-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1h)-one, compositions thereof and methods of their use |
NZ629796A (en) | 2014-07-14 | 2015-12-24 | Signal Pharm Llc | Amorphous form of 4-((4-(cyclopentyloxy)-5-(2-methylbenzo[d]oxazol-6-yl)-7h-pyrrolo[2,3-d]pyrimidin-2-yl)amino)-3-methoxy-n-methylbenzamide, compositions thereof and methods of their use |
EP3169686A4 (de) | 2014-07-14 | 2018-01-24 | Signal Pharmaceuticals, LLC | Verfahren zur behandlung von krebs mit substituierten pyrrolopyrimidinverbindungen, zusammensetzungen davon |
IL300788A (en) | 2015-11-20 | 2023-04-01 | Forma Therapeutics Inc | Furinones as ubiquitin-specific protease 1 inhibitors |
KR20200019229A (ko) | 2017-06-22 | 2020-02-21 | 셀진 코포레이션 | B형 간염 바이러스 감염을 특징으로 하는 간세포 암종의 치료 |
EP3752505B1 (de) | 2018-02-12 | 2023-01-11 | F. Hoffmann-La Roche AG | Neuartige sulfonverbindungen und derivate zur behandlung und prophylaxe einer virusinfektion |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2525595A1 (fr) | 1982-04-27 | 1983-10-28 | Pharmuka Lab | Nouveaux derives d'arene et d'heteroarenecarboxamides et leur utilisation comme medicaments |
FR2582514B1 (fr) | 1985-05-30 | 1988-02-19 | Rhone Poulenc Sante | Medicaments a base d'amides, nouveaux amides et leur preparation |
DK273689A (da) | 1988-06-06 | 1989-12-07 | Sanofi Sa | 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler |
FR2632639B1 (fr) | 1988-06-09 | 1990-10-05 | Sanofi Sa | Derives d'amino-4 carboxy-3 naphtyridines, leur preparation et compositions pharmaceutiques qui les contiennent |
US5840891A (en) | 1994-07-28 | 1998-11-24 | Syntex (U.S.A.) Inc. | 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative |
IL117659A (en) | 1995-04-13 | 2000-12-06 | Dainippon Pharmaceutical Co | Substituted 2-phenyl pyrimidino amino acetamide derivative process for preparing the same and a pharmaceutical composition containing same |
ES2232871T3 (es) | 1996-07-03 | 2005-06-01 | Sumitomo Pharmaceuticals Company, Limited | Nuevos derivados de purina. |
NZ335823A (en) * | 1997-04-22 | 2001-06-29 | Neurocrine Biosciences Inc | Thiophenopyridines, preparation as CRF receptor antagonists |
JP3814125B2 (ja) * | 1999-06-02 | 2006-08-23 | 大日本住友製薬株式会社 | 2−アリール−8−オキソジヒドロプリン誘導体からなる医薬 |
-
1998
- 1998-11-17 ZA ZA9810490A patent/ZA9810490B/xx unknown
- 1998-11-25 TW TW087119571A patent/TW502034B/zh not_active IP Right Cessation
- 1998-11-26 SK SK797-2000A patent/SK285703B6/sk unknown
- 1998-11-26 ID IDW20000990A patent/ID24929A/id unknown
- 1998-11-26 BR BR9815140-1A patent/BR9815140A/pt not_active Application Discontinuation
- 1998-11-26 ES ES98955937T patent/ES2205574T3/es not_active Expired - Lifetime
- 1998-11-26 US US09/555,490 patent/US6372740B1/en not_active Expired - Fee Related
- 1998-11-26 CA CA002312885A patent/CA2312885C/en not_active Expired - Fee Related
- 1998-11-26 DK DK98955937T patent/DK1036794T3/da active
- 1998-11-26 JP JP2000523212A patent/JP3815966B2/ja not_active Expired - Fee Related
- 1998-11-26 IL IL13592098A patent/IL135920A0/xx not_active IP Right Cessation
- 1998-11-26 WO PCT/JP1998/005320 patent/WO1999028320A1/ja active IP Right Grant
- 1998-11-26 EP EP98955937A patent/EP1036794B1/de not_active Expired - Lifetime
- 1998-11-26 AT AT98955937T patent/ATE248169T1/de not_active IP Right Cessation
- 1998-11-26 PL PL340925A patent/PL191489B1/pl unknown
- 1998-11-26 AU AU12604/99A patent/AU744014B2/en not_active Ceased
- 1998-11-26 HU HU0004422A patent/HUP0004422A3/hu unknown
- 1998-11-26 KR KR10-2000-7005968A patent/KR100494347B1/ko not_active IP Right Cessation
- 1998-11-26 NZ NZ504457A patent/NZ504457A/en unknown
- 1998-11-26 DE DE69817611T patent/DE69817611T2/de not_active Expired - Fee Related
- 1998-11-26 PT PT98955937T patent/PT1036794E/pt unknown
- 1998-11-26 TR TR2000/01600T patent/TR200001600T2/xx unknown
- 1998-11-26 RU RU2000117278/04A patent/RU2223272C2/ru not_active IP Right Cessation
- 1998-11-26 CN CNB988134519A patent/CN1146566C/zh not_active Expired - Fee Related
- 1998-12-03 AR ARP980106147A patent/AR017796A1/es active IP Right Grant
-
2000
- 2000-06-02 NO NO20002835A patent/NO20002835L/no unknown
- 2000-12-15 HK HK00108107A patent/HK1028769A1/xx not_active IP Right Cessation
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