ATE245655T1 - Organische-arsenverbindungen - Google Patents

Organische-arsenverbindungen

Info

Publication number
ATE245655T1
ATE245655T1 AT00919444T AT00919444T ATE245655T1 AT E245655 T1 ATE245655 T1 AT E245655T1 AT 00919444 T AT00919444 T AT 00919444T AT 00919444 T AT00919444 T AT 00919444T AT E245655 T1 ATE245655 T1 AT E245655T1
Authority
AT
Austria
Prior art keywords
arsenic compounds
organic arsenic
cancer cells
cells
regard
Prior art date
Application number
AT00919444T
Other languages
English (en)
Inventor
Fatih M Uckun
Xing-Ping Liu
Original Assignee
Parker Hughes Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Parker Hughes Inst filed Critical Parker Hughes Inst
Application granted granted Critical
Publication of ATE245655T1 publication Critical patent/ATE245655T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/66—Arsenic compounds
    • C07F9/70—Organo-arsenic compounds
    • C07F9/80—Heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT00919444T 1999-03-19 2000-03-16 Organische-arsenverbindungen ATE245655T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US12533799P 1999-03-19 1999-03-19
US09/338,680 US6191123B1 (en) 1999-03-19 1999-06-23 Organic-arsenic compounds
PCT/US2000/007063 WO2000056742A1 (en) 1999-03-19 2000-03-16 Organic-arsenic compounds

Publications (1)

Publication Number Publication Date
ATE245655T1 true ATE245655T1 (de) 2003-08-15

Family

ID=26823484

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00919444T ATE245655T1 (de) 1999-03-19 2000-03-16 Organische-arsenverbindungen

Country Status (8)

Country Link
US (3) US6191123B1 (de)
EP (1) EP1163246B1 (de)
JP (1) JP2002540114A (de)
AT (1) ATE245655T1 (de)
AU (1) AU4013400A (de)
CA (1) CA2365201A1 (de)
DE (1) DE60004027T2 (de)
WO (1) WO2000056742A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6191123B1 (en) * 1999-03-19 2001-02-20 Parker Hughes Institute Organic-arsenic compounds
AUPQ296799A0 (en) 1999-09-20 1999-10-14 Unisearch Limited A cell-membrane impermeable trivalent organoarsenical derivative and use thereof
AUPR379801A0 (en) 2001-03-19 2001-04-12 Unisearch Limited Use of a substantially cell membrane impermeable compound for treating arthritis
AUPR874601A0 (en) * 2001-11-08 2001-11-29 Unisearch Limited Selective targeting of apoptotic cells
GB0128405D0 (en) * 2001-11-27 2002-01-16 Btg Int Ltd Process for fabricating polyolefin sheet
US20030135041A1 (en) * 2002-01-04 2003-07-17 Orchid Chemicals & Pharmaceuticals Limited, India Synthesis of ceftiofur intermediate
WO2003057012A2 (en) * 2002-01-07 2003-07-17 Board Of Regents, The University Of Texas System S-dimethylarsino-thiosuccinic acid s-dimethylarsino-2-thiobenzoic acid s-(dimethylarsino) glutathione as treatments for cancer
FR2838965B1 (fr) 2002-04-26 2004-06-25 Centre Nat Rech Scient Therapie par l'arsenic du syndrome autoimmunlymphoproliferatif de type apls chez la souris comme chez l'homme
US8394422B2 (en) * 2002-04-26 2013-03-12 Centre National De La Recherche Scientifique (Cnrs) Arsenic therapy for autoimmune and/or inflammatory diseases in mice and humans
CA2504935C (en) 2002-11-07 2012-04-10 Unisearch Limited Induction of the mitochondrial permeability transition
US6686344B1 (en) 2003-01-30 2004-02-03 Paker Hughes Institute Organic-arsonic compounds
TW201350113A (zh) * 2004-07-16 2013-12-16 Texas A & M Univ Sys 有機砷化合物、其用於治療癌症之用途及包含其之醫藥組成物
WO2007027344A2 (en) * 2005-07-29 2007-03-08 Ziopharm Oncology, Inc. Compounds and methods for the treatment of cancer
TW200829261A (en) * 2006-09-29 2008-07-16 Ziopharm Oncology Inc Method for controlling angiogenesis in animals
JP5301449B2 (ja) 2006-11-01 2013-09-25 ニューサウス イノベイションズ ピーティーワイ リミテッド 有機アルセノキシド化合物およびその使用
ES2392737T3 (es) * 2007-11-02 2012-12-13 Ziopharm Oncology, Inc. Terapia combinada con compuestos arsenicales orgánicos
CN101874034A (zh) * 2007-12-12 2010-10-27 Zio医药肿瘤学公司 用于治疗癌症的化合物和方法
BRPI0918407A2 (pt) 2008-08-20 2015-11-24 Ziopharm Oncology Inc compostos organoarsênicos e métodos para o tratamento de câncer
CA2748491C (en) 2008-12-30 2019-08-06 Arqule, Inc. Substituted 5,6-dihydro-6-phenylbenzo[f]isoquinolin-2-amine compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3017380A (en) * 1958-12-05 1962-01-16 Dal Mon Research Co Aldehyde-triazinyl arsenic condensation products and method of making same
SU977461A1 (ru) * 1981-04-28 1982-11-30 Ордена Ленина Институт Геохимии И Аналитической Химии Им.В.И.Вернадского Способ получени 2,7-бис-(2-арсонофенилазо)-1,8-диоксинафталин-3,6-дисульфокислоты (арсеназо ш)
FR2640269B1 (fr) * 1988-12-13 1991-03-15 Maes Ludo Composes organometalliques, leurs modes de preparation et compositions pharmaceutiques les contenant
FR2684382B1 (fr) * 1991-12-02 1994-10-21 Rhone Merieux Medicaments et preparations pures de dichlorhydrate de melarsomine, leur procede d'obtention et produits intermediaires obtenus.
ATE232104T1 (de) * 1994-11-30 2003-02-15 Univ Hospital Arzneimittel zur behandlung von parasitischen und pilzartigen infektionen
US6191123B1 (en) * 1999-03-19 2001-02-20 Parker Hughes Institute Organic-arsenic compounds

Also Published As

Publication number Publication date
JP2002540114A (ja) 2002-11-26
AU4013400A (en) 2000-10-09
EP1163246B1 (de) 2003-07-23
CA2365201A1 (en) 2000-09-28
WO2000056742A1 (en) 2000-09-28
US6482816B1 (en) 2002-11-19
EP1163246A1 (de) 2001-12-19
US6482815B1 (en) 2002-11-19
DE60004027T2 (de) 2004-04-22
DE60004027D1 (de) 2003-08-28
US6191123B1 (en) 2001-02-20
WO2000056742A9 (en) 2001-11-01

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties