ATE236145T1 - Verfahren zur herstellung von 5-cyanophthalid - Google Patents

Verfahren zur herstellung von 5-cyanophthalid

Info

Publication number
ATE236145T1
ATE236145T1 AT99960958T AT99960958T ATE236145T1 AT E236145 T1 ATE236145 T1 AT E236145T1 AT 99960958 T AT99960958 T AT 99960958T AT 99960958 T AT99960958 T AT 99960958T AT E236145 T1 ATE236145 T1 AT E236145T1
Authority
AT
Austria
Prior art keywords
cyanophthalide
producing
Prior art date
Application number
AT99960958T
Other languages
English (en)
Inventor
Hans Petersen
Nielsen Poul Dahlberg
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of ATE236145T1 publication Critical patent/ATE236145T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Furan Compounds (AREA)
AT99960958T 1998-12-23 1999-12-22 Verfahren zur herstellung von 5-cyanophthalid ATE236145T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA199801718 1998-12-23
PCT/DK1999/000728 WO2000039112A1 (en) 1998-12-23 1999-12-22 Method for the preparation of 5-cyanophthalide

Publications (1)

Publication Number Publication Date
ATE236145T1 true ATE236145T1 (de) 2003-04-15

Family

ID=8107494

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99960958T ATE236145T1 (de) 1998-12-23 1999-12-22 Verfahren zur herstellung von 5-cyanophthalid

Country Status (31)

Country Link
US (1) US6392060B2 (de)
EP (1) EP1140886B1 (de)
JP (1) JP2002533450A (de)
KR (1) KR100454008B1 (de)
CN (1) CN1149208C (de)
AR (1) AR019791A1 (de)
AT (1) ATE236145T1 (de)
AU (1) AU764161B2 (de)
BG (1) BG64986B1 (de)
BR (1) BR9916955A (de)
CA (1) CA2356188C (de)
CZ (1) CZ300408B6 (de)
DE (1) DE69906580T2 (de)
DK (1) DK1140886T3 (de)
EA (1) EA003057B1 (de)
ES (1) ES2195644T3 (de)
HK (1) HK1043130B (de)
HU (1) HUP0104856A3 (de)
IL (1) IL143422A0 (de)
IS (1) IS2261B (de)
IT (1) IT1315269B1 (de)
NO (1) NO326516B1 (de)
NZ (1) NZ512073A (de)
PL (1) PL203275B1 (de)
PT (1) PT1140886E (de)
SI (1) SI1140886T1 (de)
SK (1) SK285530B6 (de)
TR (1) TR200101796T2 (de)
UA (1) UA70979C2 (de)
WO (1) WO2000039112A1 (de)
ZA (1) ZA200104262B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1123284T3 (da) 1998-10-20 2003-04-28 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
SI1140886T1 (en) 1998-12-23 2003-08-31 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
AR022329A1 (es) * 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
HU227473B1 (en) 1999-04-14 2011-07-28 Lundbeck & Co As H Method for preparation of citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ATE277032T1 (de) 1999-10-25 2004-10-15 Lundbeck & Co As H Verfahren zur herstellung von citalopram
SK287139B6 (sk) 1999-10-25 2010-01-07 H. Lundbeck A/S Spôsob prípravy citalopramu
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
AU778751B2 (en) 1999-12-28 2004-12-16 H. Lundbeck A/S Method for the preparation of citalopram
EP1246813B1 (de) 1999-12-30 2003-11-05 H. Lundbeck A/S Verfahren zur herstellung von citalopram
EA005134B1 (ru) 2000-01-14 2004-12-30 Х.Лундбекк А/С Способ получения 5-цианофталида
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
TR200202195T2 (tr) 2000-03-13 2002-12-23 H. Lundbeck A/S 5-Yer değiştirmiş 1-(4-florofenil)-1,3- dihidroizobenzofuran'ın adım adım alkillenmesi
EA200200969A1 (ru) 2000-03-13 2003-02-27 Х.Лундбекк А/С Способ получения циталопрама
ES2214400T3 (es) 2000-03-14 2004-09-16 H. Lundbeck A/S Metodo para la preparacion de citalopram.
JP2003527388A (ja) * 2000-03-16 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット 5−シアノ−1−(4−フルオロフェニル)−1,3−ジヒドロイソベンゾフランの製造方法
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CA2354877C (en) * 2000-08-18 2006-05-02 H. Lundbeck A/S Method for the preparation of citalopram
SI1181713T1 (en) 2000-12-22 2005-02-28 H. Lundbeck A/S Method for the preparation of pure citalopram
CA2359810C (en) 2000-12-28 2002-11-05 H. Lundbeck A/S Process for the preparation of pure citalopram
EP1321464A1 (de) * 2001-12-21 2003-06-25 ICROM S.p.A. Verfahren zur Herstellung von 5-Cyanphthalid und dafür benötigte Zwischenprodeukte
WO2004083197A2 (en) * 2003-03-21 2004-09-30 H. Lundbeck A/S Intermediates for the preparation of citalopram and escitalopram
WO2004085416A1 (en) * 2003-03-24 2004-10-07 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
EP1777221A1 (de) 2005-10-14 2007-04-25 Adorkem Technology SpA Procédé pour la préparation du 5-cyanophtalide à partir du 5-carboxyphtalide

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143702A (de) 1965-03-18
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) * 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DK213290D0 (da) 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
JP3526581B2 (ja) * 1997-07-08 2004-05-17 ハー・ルンドベック・アクティーゼルスカブ シタロプラムの製造方法
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
CA2291072C (en) 1997-11-11 2002-08-20 H. Lundbeck A/S Method for the preparation of citalopram
DK1123284T3 (da) 1998-10-20 2003-04-28 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
SI1140886T1 (en) 1998-12-23 2003-08-31 H. Lundbeck A/S Method for the preparation of 5-cyanophthalide
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
HU227473B1 (en) 1999-04-14 2011-07-28 Lundbeck & Co As H Method for preparation of citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
SK287139B6 (sk) 1999-10-25 2010-01-07 H. Lundbeck A/S Spôsob prípravy citalopramu
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate

Also Published As

Publication number Publication date
BR9916955A (pt) 2001-09-11
HUP0104856A2 (hu) 2002-04-29
AU1774200A (en) 2000-07-31
HK1043130A1 (en) 2002-09-06
US20020019546A1 (en) 2002-02-14
WO2000039112A1 (en) 2000-07-06
AR019791A1 (es) 2002-03-13
EP1140886A1 (de) 2001-10-10
NZ512073A (en) 2003-10-31
DE69906580D1 (de) 2003-05-08
CA2356188C (en) 2006-05-23
BG105655A (en) 2002-01-31
IL143422A0 (en) 2002-04-21
DK1140886T3 (da) 2003-07-28
TR200101796T2 (tr) 2001-11-21
DE69906580T2 (de) 2004-02-12
EA003057B1 (ru) 2002-12-26
NO326516B1 (no) 2008-12-22
IT1315269B1 (it) 2003-02-03
KR20010082370A (ko) 2001-08-29
ITMI992696A1 (it) 2001-06-23
PL348608A1 (en) 2002-06-03
ZA200104262B (en) 2001-12-11
NO20013150L (no) 2001-08-20
PT1140886E (pt) 2003-08-29
CA2356188A1 (en) 2000-07-06
IS5952A (is) 2001-05-22
NO20013150D0 (no) 2001-06-22
SI1140886T1 (en) 2003-08-31
IS2261B (is) 2007-06-15
BG64986B1 (bg) 2006-11-30
CN1331686A (zh) 2002-01-16
HK1043130B (zh) 2005-03-04
HUP0104856A3 (en) 2003-01-28
SK8962001A3 (en) 2003-03-04
JP2002533450A (ja) 2002-10-08
CZ300408B6 (cs) 2009-05-13
CN1149208C (zh) 2004-05-12
AU764161B2 (en) 2003-08-14
SK285530B6 (sk) 2007-03-01
CZ20012335A3 (cs) 2001-12-12
PL203275B1 (pl) 2009-09-30
KR100454008B1 (ko) 2004-10-20
EA200100696A1 (ru) 2001-12-24
ITMI992696A0 (it) 1999-12-23
EP1140886B1 (de) 2003-04-02
US6392060B2 (en) 2002-05-21
UA70979C2 (uk) 2004-11-15
ES2195644T3 (es) 2003-12-01

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