ATE222909T1 - Verfahren zur herstellung von purin-derivaten - Google Patents

Verfahren zur herstellung von purin-derivaten

Info

Publication number: ATE222909T1
Authority: AT; Austria
Prior art keywords: purine derivatives; intermediates; producing purine; purin; propanediol
Prior art date: 1996-01-26

Application number

AT97901569T

Other languages

English (en)

Inventor

Humberto B Arzeno

Steven D Axt

Colin C Beard

Charles A Dvorak

Paul R Fatheree

Lawrence E Fisher

Yeun-Kwei Han

Eric R Humphreys

Jan P Lund

Sam Linh Nguyen

Douglas Leslie Wren

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-01-26

Filing date

1997-01-21

Publication date

2002-09-15

1997-01-21 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2002-09-15 Application granted granted Critical

2002-09-15 Publication of ATE222909T1 publication Critical patent/ATE222909T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT97901569T 1996-01-26 1997-01-21 Verfahren zur herstellung von purin-derivaten ATE222909T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US59207996A	1996-01-26	1996-01-26
PCT/EP1997/000262 WO1997027198A1 (en)	1996-01-26	1997-01-21	Process for preparing purine derivatives

Publications (1)

Publication Number	Publication Date
ATE222909T1 true ATE222909T1 (de)	2002-09-15

Family

ID=24369197

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97901569T ATE222909T1 (de)	1996-01-26	1997-01-21	Verfahren zur herstellung von purin-derivaten

Country Status (10)

Country	Link
JP (1)	JP4094667B2 (de)
KR (1)	KR100491941B1 (de)
CN (1)	CN1064683C (de)
AT (1)	ATE222909T1 (de)
AU (1)	AU1543797A (de)
CA (1)	CA2243650C (de)
DE (1)	DE69714971T3 (de)
ES (1)	ES2180923T5 (de)
MX (1)	MX9805935A (de)
WO (1)	WO1997027198A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6703394B2 (en)	1996-02-16	2004-03-09	Medivir Ab	Acyclic nucleoside derivatives
US5869493A (en)	1996-02-16	1999-02-09	Medivir Ab	Acyclic nucleoside derivatives
CA2537849A1 (en) *	2003-09-11	2005-03-17	F. Hoffmann-La Roche Ag	Process for preparing antiviral nucleoside derivatives
ZA200702234B (en) *	2006-03-21	2008-07-30	Cipla Ltd	Preparation of ester of purine derivatives
WO2012163373A1 (en) *	2011-05-31	2012-12-06	Pharmathen S.A.	Process for the preparation of 2-amino-9-((2-phenyl-1,3-dioxan-5-yloxy)methyl)-1h-purin-6(9h)-one compound useful in the preparation of valganciclovir

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4816447A (en) *	1981-08-26	1989-03-28	Merck & Co., Inc.	Anti-viral guanine compounds
NL8202626A (nl) *	1982-06-29	1984-01-16	Stichting Rega V Z W	Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
AP160A (en) *	1987-08-15	1991-11-18	The Wellcome Foundation Ltd	Therapeutic acyclic nucleosides.
AU618436B2 (en) *	1988-12-19	1991-12-19	Wellcome Foundation Limited, The	Antiviral cytosine and guanine derivatives
JP3225545B2 (ja) *	1991-09-18	2001-11-05	味の素株式会社	非環状ヌクレオシド類の製造法
PE32296A1 (es) *	1994-07-28	1996-08-07	Hoffmann La Roche	Ester de l-monovalina derivado de 2-(2-amino-1,6-dihidro-6-oxo-purin-9-il) metoxi-1,3-propandiol y sus sales farmaceuticamente aceptables

1997
- 1997-01-21 ES ES97901569T patent/ES2180923T5/es not_active Expired - Lifetime
- 1997-01-21 AT AT97901569T patent/ATE222909T1/de active
- 1997-01-21 KR KR10-1998-0705709A patent/KR100491941B1/ko not_active IP Right Cessation
- 1997-01-21 WO PCT/EP1997/000262 patent/WO1997027198A1/en active IP Right Grant
- 1997-01-21 CA CA002243650A patent/CA2243650C/en not_active Expired - Lifetime
- 1997-01-21 AU AU15437/97A patent/AU1543797A/en not_active Abandoned
- 1997-01-21 CN CN97192606A patent/CN1064683C/zh not_active Expired - Lifetime
- 1997-01-21 JP JP52651797A patent/JP4094667B2/ja not_active Expired - Lifetime
- 1997-01-21 DE DE69714971T patent/DE69714971T3/de not_active Expired - Lifetime
1998
- 1998-07-23 MX MX9805935A patent/MX9805935A/es unknown

Also Published As

Publication number	Publication date
CN1064683C (zh)	2001-04-18
ES2180923T5 (es)	2005-10-16
KR19990081991A (ko)	1999-11-15
AU1543797A (en)	1997-08-20
DE69714971D1 (de)	2002-10-02
DE69714971T3 (de)	2005-12-15
JP4094667B2 (ja)	2008-06-04
JP2000503977A (ja)	2000-04-04
ES2180923T3 (es)	2003-02-16
KR100491941B1 (ko)	2005-08-05
DE69714971T2 (de)	2003-05-28
CA2243650C (en)	2006-08-15
MX9805935A (es)	1998-11-30
CA2243650A1 (en)	1997-07-31
WO1997027198A1 (en)	1997-07-31
CN1212693A (zh)	1999-03-31

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Legal Events

Date

Code

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Description

2003-01-15

UEP

Publication of translation of european patent specification

2006-09-15

UEP

Publication of translation of european patent specification

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