ATE206118T1 - Indolyl-pyrrolylidenmethylpyrrol-derivate und verfahren zu ihrer herstellung - Google Patents

Indolyl-pyrrolylidenmethylpyrrol-derivate und verfahren zu ihrer herstellung

Info

Publication number
ATE206118T1
ATE206118T1 AT98913665T AT98913665T ATE206118T1 AT E206118 T1 ATE206118 T1 AT E206118T1 AT 98913665 T AT98913665 T AT 98913665T AT 98913665 T AT98913665 T AT 98913665T AT E206118 T1 ATE206118 T1 AT E206118T1
Authority
AT
Austria
Prior art keywords
pyrrolylidene
methylpyrrole
indolyl
derivatives
production
Prior art date
Application number
AT98913665T
Other languages
English (en)
Inventor
Alessio Roberto D
Marcellino Tibolla
Alberto Bargiotti
Anna Maria Isetta
Mario Ferrari
Francesco Colotta
Original Assignee
Pharmacia & Upjohn Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn Spa filed Critical Pharmacia & Upjohn Spa
Application granted granted Critical
Publication of ATE206118T1 publication Critical patent/ATE206118T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
AT98913665T 1997-03-11 1998-02-27 Indolyl-pyrrolylidenmethylpyrrol-derivate und verfahren zu ihrer herstellung ATE206118T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9705035.5A GB9705035D0 (en) 1997-03-11 1997-03-11 Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation
PCT/EP1998/001285 WO1998040380A1 (en) 1997-03-11 1998-02-27 Indolyl-pyrrolydenemethylpyrrole derivatives and process for their preparation

Publications (1)

Publication Number Publication Date
ATE206118T1 true ATE206118T1 (de) 2001-10-15

Family

ID=10809054

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98913665T ATE206118T1 (de) 1997-03-11 1998-02-27 Indolyl-pyrrolylidenmethylpyrrol-derivate und verfahren zu ihrer herstellung

Country Status (26)

Country Link
US (1) US6071947A (de)
EP (1) EP0909271B1 (de)
JP (1) JP2000510873A (de)
KR (1) KR20000010913A (de)
CN (1) CN1089763C (de)
AR (1) AR011964A1 (de)
AT (1) ATE206118T1 (de)
AU (1) AU740583B2 (de)
BR (1) BR9805938A (de)
CA (1) CA2253588A1 (de)
DE (1) DE69801795T2 (de)
DK (1) DK0909271T3 (de)
EA (1) EA001055B1 (de)
ES (1) ES2165150T3 (de)
GB (1) GB9705035D0 (de)
HU (1) HUP0003614A3 (de)
IL (1) IL126839A (de)
MY (1) MY117159A (de)
NO (1) NO316754B1 (de)
NZ (1) NZ333015A (de)
PL (1) PL329808A1 (de)
PT (1) PT909271E (de)
TW (1) TW568911B (de)
UA (1) UA56169C2 (de)
WO (1) WO1998040380A1 (de)
ZA (1) ZA981976B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US6407244B1 (en) 2000-01-26 2002-06-18 Gemin X Biotechnologies Inc. Pyrrole-type compounds, compositions, and methods for treating cancer or viral diseases
US20040014987A1 (en) 2000-01-26 2004-01-22 Gemin X Biotechnologies Inc. Pyrrole-Type compounds, compositions, and methods for treating cancer or viral diseases
DE10038699A1 (de) * 2000-07-31 2002-02-14 Michael Sittinger Mittel zur Verringrung der Abstoßungsreaktionen bei Transplantaten
CA2453636A1 (en) 2001-07-18 2003-01-30 Gemin X Biotechnologies Inc. Polypyrroles as agents for treating cancer, treating viral diseases and causing immunosuppression
AU2003207774A1 (en) * 2002-01-30 2003-09-02 Montana State University Pestalotiopsis microsporia isolates and compounds derived therefrom
US7968569B2 (en) * 2002-05-17 2011-06-28 Celgene Corporation Methods for treatment of multiple myeloma using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione
ZA200509718B (en) * 2003-05-30 2007-03-28 Gemin X Biotechnologies Inc Triheterocyclic compounds, compositions, and methods for treating cancer or viral diseases
EP1768662A2 (de) 2004-06-24 2007-04-04 Novartis Vaccines and Diagnostics, Inc. Immunstimulatoren kleiner moleküle und assays für deren nachweis
ES2454551T3 (es) * 2004-12-28 2014-04-10 Gemin X Pharmaceuticals Canada Inc. Compuestos dipirrólicos, composiciones, y métodos para el tratamiento del cáncer o enfermedades virales
WO2006089397A1 (en) * 2005-02-22 2006-08-31 Gemin X Biotechnologies Inc. Methods for treating arthritis using triheterocyclic compounds
DE102005025225A1 (de) 2005-06-01 2006-12-07 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von 2-(2-Amino-pyrimidin-4-yl)-1H-indol-5-carbonsäure-derivaten
US20080051400A1 (en) * 2006-07-06 2008-02-28 Gemin X Biotechnologies Inc. Methods for treating or preventing anemia or thrombocytopenia using a triheterocyclic compound
CN113845524B (zh) * 2021-10-29 2023-11-07 四川农业大学 一种螺吡咯吲哚酮类化合物及其制备方法和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61280429A (ja) * 1985-06-06 1986-12-11 Chugai Pharmaceut Co Ltd 免疫抑制剤
EP0695301B1 (de) * 1993-04-22 1996-10-30 Pfizer Limited Indol-derivate als 5-ht1-ähnliche antagonisten zur behandlung von migräne
GB9326284D0 (en) * 1993-12-23 1994-02-23 Erba Carlo Spa Pyrrolydenemethyl-derivatives and process for their preparation
GB9603212D0 (en) * 1996-02-15 1996-04-17 Pharmacia Spa Process for the preparation of 2,2'-bipyrrolyl-pyrromethane derivatives

Also Published As

Publication number Publication date
NZ333015A (en) 2000-04-28
UA56169C2 (uk) 2003-05-15
US6071947A (en) 2000-06-06
EP0909271B1 (de) 2001-09-26
EA001055B1 (ru) 2000-08-28
EA199801004A1 (ru) 1999-06-24
BR9805938A (pt) 1999-08-31
WO1998040380A1 (en) 1998-09-17
HUP0003614A2 (hu) 2001-10-28
AR011964A1 (es) 2000-09-13
IL126839A0 (en) 1999-09-22
NO985248L (no) 1999-01-11
DK0909271T3 (da) 2002-01-28
JP2000510873A (ja) 2000-08-22
IL126839A (en) 2002-12-01
TW568911B (en) 2004-01-01
CN1089763C (zh) 2002-08-28
PL329808A1 (en) 1999-04-12
AU6828398A (en) 1998-09-29
AU740583B2 (en) 2001-11-08
PT909271E (pt) 2002-03-28
NO985248D0 (no) 1998-11-10
ZA981976B (en) 1998-09-09
ES2165150T3 (es) 2002-03-01
CA2253588A1 (en) 1998-09-17
DE69801795D1 (de) 2001-10-31
DE69801795T2 (de) 2002-05-23
MY117159A (en) 2004-05-31
NO316754B1 (no) 2004-04-26
CN1222911A (zh) 1999-07-14
KR20000010913A (ko) 2000-02-25
GB9705035D0 (en) 1997-04-30
EP0909271A1 (de) 1999-04-21
HUP0003614A3 (en) 2003-04-28

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee