ATE189607T1 - Dna codierend für einen menschlichen neuropeptid y/peptid yy/pankreaspolypeptid-rezeptor (y4) und seine verwendung - Google Patents

Dna codierend für einen menschlichen neuropeptid y/peptid yy/pankreaspolypeptid-rezeptor (y4) und seine verwendung

Info

Publication number: ATE189607T1
Authority: AT; Austria
Prior art keywords: human; receptor; nucleic acid; acid molecule; encoding
Prior art date: 1993-12-28

Application number

AT95907215T

Other languages

English (en)

Inventor

Jonathan A Bard

Mary W Walker

Theresa Branchek

Richard L Weinshank

Original Assignee

Synaptic Pharma Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-12-28

Filing date

1994-12-28

Publication date

2000-02-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22644257&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE189607(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1994-12-28 Application filed by Synaptic Pharma Corp filed Critical Synaptic Pharma Corp

2000-02-15 Application granted granted Critical

2000-02-15 Publication of ATE189607T1 publication Critical patent/ATE189607T1/de

Links

101500025005 Homo sapiens Neuropeptide Y Proteins 0.000 title 1
101000585528 Homo sapiens Peptide YY Proteins 0.000 title 1
XKWCTHKJQNUFOQ-HRPSIEBRSA-N gtpl1504 Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(N)=O)NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CCCCN)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)CC=1C=CC(O)=CC=1)C1=CC=C(O)C=C1 XKWCTHKJQNUFOQ-HRPSIEBRSA-N 0.000 title 1
210000000496 pancreas Anatomy 0.000 title 1
229920001184 polypeptide Polymers 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
102000028435 Neuropeptide Y4 receptor Human genes 0.000 abstract 9
108010002245 Neuropeptide Y4 receptor Proteins 0.000 abstract 9
102000039446 nucleic acids Human genes 0.000 abstract 4
108020004707 nucleic acids Proteins 0.000 abstract 4
150000007523 nucleic acids Chemical class 0.000 abstract 4
239000013598 vector Substances 0.000 abstract 2
108020000948 Antisense Oligonucleotides Proteins 0.000 abstract 1
241001465754 Metazoa Species 0.000 abstract 1
108020004711 Nucleic Acid Probes Proteins 0.000 abstract 1
239000000074 antisense oligonucleotide Substances 0.000 abstract 1
238000012230 antisense oligonucleotides Methods 0.000 abstract 1
230000000295 complement effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
238000007877 drug screening Methods 0.000 abstract 1
239000003446 ligand Substances 0.000 abstract 1
210000004962 mammalian cell Anatomy 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000002853 nucleic acid probe Substances 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
230000009261 transgenic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, ***e
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Cardiology (AREA)
Zoology (AREA)
Toxicology (AREA)
Immunology (AREA)
Cell Biology (AREA)
Hospice & Palliative Care (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Tropical Medicine & Parasitology (AREA)
Urology & Nephrology (AREA)
Hematology (AREA)
Reproductive Health (AREA)
Child & Adolescent Psychology (AREA)

AT95907215T 1993-12-28 1994-12-28 Dna codierend für einen menschlichen neuropeptid y/peptid yy/pankreaspolypeptid-rezeptor (y4) und seine verwendung ATE189607T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/176,412 US5516653A (en)	1993-12-28	1993-12-28	DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof
PCT/US1994/014436 WO1995017906A1 (en)	1993-12-28	1994-12-28	Dna encoding a human neuropeptide y/peptide yy/pancreatic polypeptide receptor (y4) and uses thereof

Publications (1)

Publication Number	Publication Date
ATE189607T1 true ATE189607T1 (de)	2000-02-15

Family

ID=22644257

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95907215T ATE189607T1 (de)	1993-12-28	1994-12-28	Dna codierend für einen menschlichen neuropeptid y/peptid yy/pankreaspolypeptid-rezeptor (y4) und seine verwendung

Country Status (11)

Country	Link
US (4)	US5516653A (de)
EP (1)	EP0746332B2 (de)
JP (1)	JP4216326B2 (de)
AT (1)	ATE189607T1 (de)
AU (1)	AU702438B2 (de)
CA (1)	CA2156272C (de)
DE (2)	DE746332T1 (de)
DK (1)	DK0746332T4 (de)
ES (1)	ES2097717T5 (de)
GR (1)	GR970300026T1 (de)
WO (1)	WO1995017906A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5516653A (en)	1993-12-28	1996-05-14	Synaptic Pharmaceutical Corporation	DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof
US5545549A (en) *	1994-02-03	1996-08-13	Synaptic Pharmaceutical Corporation	DNA encoding a human neuropeptide Y/peptide YY (Y2) receptor and uses thereof
EP0791009A4 (de) *	1994-11-07	2003-03-05	Merck & Co Inc	Modifizierter neuropeptid-y-rezeptor
US5989920A (en)	1994-12-02	1999-11-23	Synaptic Pharmaceutical Corporation	Methods of modifying feeding behavior compounds useful in such methods and DNA encoding a hypothalmic atypical neuropeptide Y/peptide YY receptor Y5
US5602024A (en) *	1994-12-02	1997-02-11	Synaptic Pharmaceutical Corporation	DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof
US5965392A (en) *	1996-04-08	1999-10-12	Bayer Corporation	Neuropeptide Y receptor Y5 and nucleic acid sequences
US5919901A (en) *	1996-04-08	1999-07-06	Bayer Corporation	Neuropeptide Y receptor Y5 and nucleic acid sequences
US5908830A (en) *	1996-10-31	1999-06-01	Merck & Co., Inc.	Combination therapy for the treatment of diabetes and obesity
US6713265B1 (en)	1997-06-04	2004-03-30	Synaptic Pharmaceutical Corporation	Methods of modifying feeding behavior, compounds useful in such methods, and DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5)
US5916869A (en) *	1997-06-13	1999-06-29	North Carolina State University	Method of treating birds in ovo
GB2344050A (en) *	1998-11-26	2000-05-31	Ferring Bv	Agents useful in the treatment of reproductive disorders.
US7745216B2 (en)	1999-02-10	2010-06-29	Curis, Inc.	Methods and reagents for treating glucose metabolic disorders
US6221660B1 (en)	1999-02-22	2001-04-24	Synaptic Pharmaceutical Corporation	DNA encoding SNORF25 receptor
AU6727900A (en) *	1999-08-27	2001-03-26	Takeda Chemical Industries Ltd.	Novel g protein-coupled receptor protein and dna thereof
AU2001232900A1 (en) *	2000-01-20	2001-07-31	Michael Amling	Methods and compositions for control of bone formation via modulation of neuropeptide y activity
CA2422956C (en)	2000-10-23	2010-10-19	Gen-Probe Incorporated	Compositions and methods for detecting human immunodeficiency virus 2 (hiv-2)
EP1403380A1 (de) *	2002-09-27	2004-03-31	Integragen	Humanes fettleibigkeit Suszeptibilitätsgen und deren Verwendungen
EP1995331A1 (de) *	2002-05-15	2008-11-26	Integragen	Menschliches Adipositas-Suszeptibilitäsgen und Verwendungen davon
EP1362926A1 (de) *	2002-05-15	2003-11-19	Integragen	Humanes fettleibigkeit Suszeptibilitätsgen und deren Verwendungen
US7811989B2 (en)	2003-01-17	2010-10-12	Ipsen Pharma S.A.S.	Peptide YY analogs
US20070042433A1 (en) *	2003-03-26	2007-02-22	Jianxin Bao	Neuregulin protein regulation of synaptic proteins
JPWO2005042742A1 (ja) *	2003-10-30	2008-02-21	萬有製薬株式会社	サルｎｐｙｙ４受容体及び化合物の評価方法
US20070270339A1 (en) *	2004-04-23	2007-11-22	Serono, Inc.	Use of GPCR54 Ligands for the Treatment of Infertility
CA2565801A1 (en) *	2004-05-28	2005-12-15	Applied Research Systems Ars Holding N.V.	Use of il-17 in the treatment of fertility-related disorders
PA8660701A1 (es) *	2005-02-04	2006-09-22	Pfizer Prod Inc	Agonistas de pyy y sus usos
WO2006091506A2 (en) *	2005-02-24	2006-08-31	Bayer Pharmaceuticals Corporation	Neuropeptide y4 receptor agonists
EP1934254A1 (de) *	2005-09-21	2008-06-25	7TM Pharma A/S	Selektive y4 rezeptor agonisten für therapeutische eingriffe
JP2009508886A (ja)	2005-09-21	2009-03-05	７ティーエムファーマエイ／エス	治療的介入のためのｙ２選択性レセプターアゴニスト
US20070197445A1 (en) *	2006-01-18	2007-08-23	University Of Cincinnati	Compounds for control of appetite
EP1990427A4 (de)	2006-02-24	2009-04-29	Banyu Pharma Co Ltd	Npy y4-agonist als therapeutikum gegen eine von einer fehlfunktion des darmtrakts begleitete krankheit
US20120040886A1 (en) *	2009-02-20	2012-02-16	Zheng Xin Dong	Analogues of Neuropeptide Y Having Proline Substitution At Position 34

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US4839343A (en) *	1987-03-13	1989-06-13	Debiopharm, S.A.	Preparation containing hexatriacontapeptides and methods of use
US5026685A (en) *	1988-07-15	1991-06-25	The Salk Institute For Biological Studies	NPY peptide analogs
US5328899A (en) *	1988-07-15	1994-07-12	The Salk Institute For Biological Studies	NPY peptide analogs
GB8818020D0 (en) *	1988-07-28	1988-09-01	Ici Plc	Method for amplification of nucleotide sequences
ZA896374B (en) *	1988-08-26	1990-05-30	Merrell Dow Pharma	Neuropeptide y antagonists
ZA896376B (en) *	1988-08-26	1990-05-30	Merrell Dow Pharma	Neuropeptide y agonists
US5053337A (en) *	1989-10-30	1991-10-01	Neurogenetic Corporation	DNA encoding an α2B -adrenergic receptor
EP0448765B1 (de) *	1990-03-30	1994-08-17	HEUMANN PHARMA GMBH & CO	Verwendung von Guanidinderivaten zur Herstellung eines Arzneimittels mit NPY-antagonistischer Wirkung
SE9002278L (sv) *	1990-06-28	1991-12-29	Perstorp Ab	Anvaendning av inositoltrisfosfat foer framstaellning av ett laekemedel
JPH0463594A (ja) *	1990-07-03	1992-02-28	Tanpaku Kogaku Kenkyusho:Kk	成長ホルモンレセプターのホルモン結合領域蛋白の製造法
CA2123108C (en) *	1991-11-06	2003-03-25	Lisa Selbie	Human neuropeptide y-y1 receptor
WO1993024515A1 (en) *	1992-05-29	1993-12-09	Cornell Research Foundation, Inc.	Human neuropeptide y/peptide yy receptor of the y1-type and antisense oligonucleotides thereto which inhibit vasoconstriction
GB9213215D0 (en) *	1992-06-20	1992-08-05	Wellcome Found	Peptides
JPH06116284A (ja) *	1992-10-02	1994-04-26	Yamanouchi Pharmaceut Co Ltd	新規ペプチド
FR2701480B1 (fr) *	1993-02-15	1995-05-24	Sanofi Elf	Composés à groupe sulfamoyle et amidino, leur procédé de préparation et les compositions pharmaceutiques les contenant.
NZ265452A (en) *	1993-03-29	1997-09-22	Univ Cincinnati	Analogues of peptide yy, dimers and pharmaceutical compositions
CA2165200A1 (en) *	1993-06-18	1995-01-05	Ambikaipakan Balasubramaniam	Neuropeptide y antagonists and agonists
US5516653A (en)	1993-12-28	1996-05-14	Synaptic Pharmaceutical Corporation	DNA encoding a human neuropeptide Y/peptide YY/pancreatic polypeptide receptor (Y4) and uses thereof
CA2134428A1 (en) *	1994-10-26	1996-04-27	Albert Tseng	Neuropeptide y y2 agonist peptides
EP0791009A4 (de) *	1994-11-07	2003-03-05	Merck & Co Inc	Modifizierter neuropeptid-y-rezeptor
US5602024A (en) *	1994-12-02	1997-02-11	Synaptic Pharmaceutical Corporation	DNA encoding a hypothalamic atypical neuropeptide Y/peptide YY receptor (Y5) and uses thereof
US5621079A (en) *	1995-02-03	1997-04-15	Merck & Co., Inc.	Neuropeptide Y receptor
AUPN646795A0 (en) *	1995-11-09	1995-11-30	Garvan Institute Of Medical Research	Neuropeptide Y-Y5 receptor
US5965392A (en) *	1996-04-08	1999-10-12	Bayer Corporation	Neuropeptide Y receptor Y5 and nucleic acid sequences
US6355478B1 (en) *	1996-06-17	2002-03-12	Eli Lilly And Company	Rhesus monkey neuropeptide Y Y2 receptor

1993
- 1993-12-28 US US08/176,412 patent/US5516653A/en not_active Expired - Lifetime
1994
- 1994-12-28 AT AT95907215T patent/ATE189607T1/de active
- 1994-12-28 US US08/495,695 patent/US5976814A/en not_active Expired - Lifetime
- 1994-12-28 ES ES95907215T patent/ES2097717T5/es not_active Expired - Lifetime
- 1994-12-28 AU AU15518/95A patent/AU702438B2/en not_active Expired
- 1994-12-28 DE DE0746332T patent/DE746332T1/de active Pending
- 1994-12-28 DE DE69423007T patent/DE69423007T3/de not_active Expired - Lifetime
- 1994-12-28 EP EP95907215A patent/EP0746332B2/de not_active Expired - Lifetime
- 1994-12-28 WO PCT/US1994/014436 patent/WO1995017906A1/en active IP Right Grant
- 1994-12-28 CA CA002156272A patent/CA2156272C/en not_active Expired - Lifetime
- 1994-12-28 DK DK95907215.8T patent/DK0746332T4/da active
- 1994-12-28 JP JP51808295A patent/JP4216326B2/ja not_active Expired - Lifetime
1995
- 1995-11-08 US US08/555,268 patent/US5958709A/en not_active Expired - Lifetime
1997
- 1997-09-30 GR GR970300026T patent/GR970300026T1/el unknown
1999
- 1999-10-29 US US09/430,775 patent/US6913892B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69423007D1 (de)	2000-03-16
JPH09511127A (ja)	1997-11-11
WO1995017906A1 (en)	1995-07-06
DK0746332T4 (da)	2010-08-16
EP0746332B2 (de)	2010-05-19
DK0746332T3 (da)	2000-06-13
US5958709A (en)	1999-09-28
CA2156272A1 (en)	1995-07-06
AU702438B2 (en)	1999-02-18
DE746332T1 (de)	1997-04-10
DE69423007T3 (de)	2011-02-10
ES2097717T1 (es)	1997-04-16
CA2156272C (en)	2009-09-15
ES2097717T5 (es)	2010-10-18
EP0746332A1 (de)	1996-12-11
US6913892B1 (en)	2005-07-05
EP0746332B1 (de)	2000-02-09
US5516653A (en)	1996-05-14
ES2097717T3 (es)	2000-06-16
AU1551895A (en)	1995-07-17
JP4216326B2 (ja)	2009-01-28
GR970300026T1 (en)	1997-09-30
US5976814A (en)	1999-11-02
EP0746332A4 (de)	1997-02-26
DE69423007T2 (de)	2000-10-19

Legal Events

Date	Code	Title	Description
2000-08-15	UEP	Publication of translation of european patent specification
2006-01-15	EEIH	Change in the person of patent owner

Publication	Publication Date	Title
ATE189607T1 (de)	2000-02-15	Dna codierend für einen menschlichen neuropeptid y/peptid yy/pankreaspolypeptid-rezeptor (y4) und seine verwendung
ES2083344T1 (es)	1996-04-16	Dna que codifica un receptor 5-ht1f humano y utilizacion del mismo.
DK0530265T3 (da)	1999-06-14	DNA kodende for humane 5-HT1D-receptorer og anvendelser deraf
WO1994014957A3 (en)	1994-08-18	Dna encoding 5-ht4 serotonin receptors and uses thereof
DK0721342T3 (da)	2002-07-15	Polypeptider fra Semaphorin genfamilien
NO20020861D0 (no)	2002-02-22	PD-1, en reseptor for B7-4, og anvendelser derav
ES2085246T1 (es)	1996-06-01	Adn que codifica un receptor humano 5-ht1e y utilizaciones del mismo.
ATE405589T1 (de)	2008-09-15	Für den snorf25-rezeptor kodierende dna
GR950300067T1 (en)	1996-01-31	Dna encoding human alpha 1 adrenergic receptors and uses thereof.
DE69417223D1 (de)	1999-04-22	Ein menschlicher t-zell rezeptor der protein g-gekoppelte rezeptor familie
EP0538395A4 (en)	1993-06-16	Nucleic acid sequences encoding a human dopamine d 1? receptor
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