DK0721342T3 - Polypeptider fra Semaphorin genfamilien - Google Patents

Polypeptider fra Semaphorin genfamilien

Info

Publication number: DK0721342T3
Authority: DK; Denmark
Prior art keywords: semaphorin; semaphorins; nucleic acids; cell growth; methods
Prior art date: 1993-09-13

Application number

DK94928057T

Other languages

English (en)

Inventor

Corey S Goodman

Alex L Kolodkin

David Matthes

David R Bentley

Timothy O'connor

Original Assignee

Univ California

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-09-13

Filing date

1994-09-13

Publication date

2002-07-15

1994-09-13 Application filed by Univ California filed Critical Univ California

2002-07-15 Application granted granted Critical

2002-07-15 Publication of DK0721342T3 publication Critical patent/DK0721342T3/da

Links

108050003978 Semaphorin Proteins 0.000 title abstract 7
229920001184 polypeptide Polymers 0.000 title 1
108090000765 processed proteins & peptides Proteins 0.000 title 1
102000004196 processed proteins & peptides Human genes 0.000 title 1
102000014105 Semaphorin Human genes 0.000 abstract 5
102000039446 nucleic acids Human genes 0.000 abstract 3
108020004707 nucleic acids Proteins 0.000 abstract 3
150000007523 nucleic acids Chemical class 0.000 abstract 3
208000012902 Nervous system disease Diseases 0.000 abstract 2
208000025966 Neurological disease Diseases 0.000 abstract 2
230000002068 genetic effect Effects 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
230000024245 cell differentiation Effects 0.000 abstract 1
230000010261 cell growth Effects 0.000 abstract 1
230000001413 cellular effect Effects 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
230000018109 developmental process Effects 0.000 abstract 1
238000013507 mapping Methods 0.000 abstract 1
230000005709 nerve cell growth Effects 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
239000000018 receptor agonist Substances 0.000 abstract 1
229940044601 receptor agonist Drugs 0.000 abstract 1
239000002464 receptor antagonist Substances 0.000 abstract 1
229940044551 receptor antagonist Drugs 0.000 abstract 1
230000008929 regeneration Effects 0.000 abstract 1
238000011069 regeneration method Methods 0.000 abstract 1
239000000523 sample Substances 0.000 abstract 1
238000012216 screening Methods 0.000 abstract 1
239000000126 substance Substances 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/033—Rearing or breeding invertebrates; New breeds of invertebrates
- A01K67/0333—Genetically modified invertebrates, e.g. transgenic, polyploid
- A01K67/0337—Genetically modified Arthropods
- A01K67/0339—Genetically modified insects, e.g. Drosophila melanogaster, medfly
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
- C07K14/4703—Inhibitors; Suppressors
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/07—Animals genetically altered by homologous recombination
- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/01—Animal expressing industrially exogenous proteins
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2267/00—Animals characterised by purpose
- A01K2267/03—Animal model, e.g. for test or diseases
- A01K2267/0306—Animal model for genetic diseases
- A01K2267/0318—Animal model for neurodegenerative disease, e.g. non- Alzheimer's
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Zoology (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biomedical Technology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Environmental Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Toxicology (AREA)
Pharmacology & Pharmacy (AREA)
General Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Immunology (AREA)
Virology (AREA)
Plant Pathology (AREA)
Microbiology (AREA)
Biodiversity & Conservation Biology (AREA)
Cell Biology (AREA)
Animal Husbandry (AREA)
Physics & Mathematics (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Neurology (AREA)
Neurosurgery (AREA)

DK94928057T 1993-09-13 1994-09-13 Polypeptider fra Semaphorin genfamilien DK0721342T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/121,713 US5639856A (en)	1993-09-13	1993-09-13	Semaphorin gene family
PCT/US1994/010151 WO1995007706A1 (en)	1993-09-13	1994-09-13	The semaphorin gene family

Publications (1)

Publication Number	Publication Date
DK0721342T3 true DK0721342T3 (da)	2002-07-15

Family

ID=22398364

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK94928057T DK0721342T3 (da)	1993-09-13	1994-09-13	Polypeptider fra Semaphorin genfamilien

Country Status (11)

Country	Link
US (8)	US5639856A (da)
EP (1)	EP0721342B1 (da)
JP (1)	JP3544378B2 (da)
AT (1)	ATE214286T1 (da)
AU (1)	AU683494B2 (da)
CA (1)	CA2171638C (da)
DE (1)	DE69430130T2 (da)
DK (1)	DK0721342T3 (da)
ES (1)	ES2173922T3 (da)
PT (1)	PT721342E (da)
WO (1)	WO1995007706A1 (da)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5639856A (en) *	1993-09-13	1997-06-17	The Regents Of The University Of California	Semaphorin gene family
US5654173A (en) *	1996-08-23	1997-08-05	Genetics Institute, Inc.	Secreted proteins and polynucleotides encoding them
ATE423847T1 (de)	1995-12-06	2009-03-15	Dainippon Sumitomo Pharma Co	Neues semaphorin z und dafür kodierendes gen
JP4108755B2 (ja) *	1996-09-11	2008-06-25	大日本住友製薬株式会社	新規セマフォリン遺伝子：セマフォリンｙ
US20070299005A1 (en) *	1996-09-24	2007-12-27	Tanox, Inc.	Family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
EP0932678B2 (en) *	1996-09-24	2010-03-10	Genentech, Inc.	A family of genes encoding apoptosis-related peptides, peptides encoded thereby and methods of use thereof
CA2268006A1 (en) *	1996-10-09	1998-04-16	Sumitomo Pharmaceuticals Co., Ltd.	Novel semaphorin gene: semaphorin w
JP4011629B2 (ja) *	1996-11-15	2007-11-21	大日本住友製薬株式会社	新規セマフォリン遺伝子（ｉ）
EP0892047A3 (de) *	1997-07-09	2000-03-08	Hoechst Marion Roussel Deutschland GmbH	Humanes und murines Semaphorin L
US6428965B1 (en) *	1997-07-17	2002-08-06	The Johns Hopkins University	Screening assays for the interaction of semaphorins and neuropilins
US20030032102A1 (en) *	1997-09-18	2003-02-13	Genentech, Inc.	Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6562949B1 (en)	1997-10-28	2003-05-13	Immunex Corporation	Antibodies to viral encoded semaphorin protein receptor polypeptides
US6130068A (en)	1998-10-26	2000-10-10	Immunex Corporation	Viral encoded semaphorin protein receptor DNA and polypeptides
WO1999021997A1 (en) *	1997-10-28	1999-05-06	Immunex Corporation	Viral encoded semaphorin protein receptor dna and polypeptides
US7214497B2 (en)	1997-10-28	2007-05-08	Immunex Corporation	Viral encoded semaphorin protein receptor DNA and polypeptides
US6635421B1 (en) *	1997-12-09	2003-10-21	Children's Medical Center Corporation	Neuropilins and use thereof in methods for diagnosis and prognosis of cancer
US6441131B1 (en)	1997-12-22	2002-08-27	Ono Pharmaceutical Co., Ltd.	Peptides, method for assaying human pepsinogen II or human pepsin II, and assaying kit
JPH11187882A (ja) *	1997-12-26	1999-07-13	Ono Pharmaceut Co Ltd	新規なポリペプチド、その製造方法、そのポリペプチドをコードするｃＤＮＡ、そのｃＤＮＡからなるベクター、そのベクターで形質転換された宿主細胞、そのポリペプチドの抗体、およびそのペプチドまたは抗体を含有する薬学的組成物
EP0933425A1 (en) *	1998-01-30	1999-08-04	Smithkline Beecham Plc	Semaphorin family polypeptides and polynucleotides
WO1999038885A2 (en) *	1998-01-30	1999-08-05	Smithkline Beecham Plc	Sbsemvl polypeptides, being members of the semaphorin protein family, and polynucleotides encoding the same
US20030166132A1 (en) *	1998-08-26	2003-09-04	Genentech, Inc.	Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2000031252A1 (en) *	1998-11-26	2000-06-02	MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.	Human semaphorin 6a-1 (sema6a-a), a gene involved in neuronal development and regeneration mechanisms during apoptosis, and its use as a potential drug target
WO2001018044A2 (en) *	1999-09-08	2001-03-15	Immunex Corporation	Use of semaphorin for modulation of cellular efflux
US20080213878A1 (en) *	1999-10-19	2008-09-04	Gregory Donoho	Novel human membrane proteins and polynucleotides encoding the same
US6750054B2 (en)	2000-05-18	2004-06-15	Lexicon Genetics Incorporated	Human semaphorin homologs and polynucleotides encoding the same
AU1450101A (en) *	1999-11-02	2001-05-14	Zymogenetics Inc.	Human semaphorin
AU4303101A (en) *	1999-11-08	2001-06-04	General Hospital Corporation, The	Novel semaphorin domains
AU2001245871B2 (en) *	2000-03-20	2006-06-01	Lexicon Pharmaceuticals, Inc.	Novel human secreted proteins and polynucleotides encoding the same
WO2001090179A2 (en) *	2000-05-23	2001-11-29	Lexicon Genetics Incorporated	Novel human thrombospondin-like proteins and polynucleotides encoding the same
AU2001276694A1 (en) *	2000-07-28	2002-02-13	Sumitomo Pharmaceuticals Company, Limited	Nerve regeneration promoters containing semaphorin inhibitor as the active ingredient
WO2003007803A2 (en) *	2001-07-20	2003-01-30	Mount Sinai School Of Medicine Of New York University	Methods for diagnosing and treating alzheimer's disease and parkinson's disease
EP1429801A1 (en) *	2001-09-26	2004-06-23	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Neuropilin as a novel therapeutic target for modulation of immune reponses
US7781413B2 (en) *	2001-10-31	2010-08-24	Board Of Regents, The University Of Texas System	SEMA3B inhibits tumor growth and induces apoptosis in cancer cells
US20030232419A1 (en) *	2002-02-04	2003-12-18	Kolodkin Alex L.	Molecules interacting with CASL (MICAL) polynucleotides, polypeptides, and methods of using the same
EP1442749A1 (en)	2003-01-31	2004-08-04	Institut National De La Sante Et De La Recherche Medicale (Inserm)	Use of anti-CD100 antibodies for the treatment and the diagnosis of inflammatory disorder affecting the central nervous system
FR2876913A1 (fr) *	2004-10-22	2006-04-28	Centre Nat Rech Scient	Modulation de la transmission synaptique par les semaphorines et ses applications
DE602008004296D1 (de)	2007-02-14	2011-02-17	Vaccinex Inc	Humanisierte anti-cd100-antikörper
PT2427212T (pt)	2009-05-08	2017-11-20	Vaccinex Inc	Anticorpos anti-cd100 e métodos para utilização dos mesmos
KR101999872B1 (ko)	2011-10-11	2019-07-12	백시넥스 인코포레이티드	혈뇌 장벽 투과성의 조정에 있어서의 세마포린-4d 결합 분자의 용도
US9090709B2 (en)	2012-03-28	2015-07-28	Vaccinex, Inc.	Anti-SEMA4D antibodies and epitopes
US10494440B2 (en)	2012-05-11	2019-12-03	Vaccinex, Inc.	Use of semaphorin-4D binding molecules to promote neurogenesis following stroke
US9975933B2 (en) *	2013-05-23	2018-05-22	Ajou University Industry-Academic Cooperation Foundation	Tumor tissue-penetrating peptide specific to neuropilin and fusion protein having same peptide fused therein
EA036591B1 (ru)	2013-06-25	2020-11-26	Вэксинекс, Инк.	Способ ингибирования, замедления или уменьшения роста раковой опухоли у субъекта
NZ630881A (en)	2013-10-10	2016-03-31	Vaccinex Inc	Use of semaphorin-4d binding molecules for treatment of atherosclerosis
NZ630892A (en)	2013-10-21	2016-03-31	Vaccinex Inc	Use of semaphorin-4d binding molecules for treating neurodegenerative disorders
CA2976593A1 (en) *	2015-02-23	2016-09-01	Seagull Therapeutics Sas	Non-natural semaphorins 3 and their medical use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA40572C2 (uk) *	1991-06-24	2001-08-15	Чірон Корпорейшн	Поліпептид, що містить укорочену послідовність вірусу гепатиту с, ізольований епітоп, реагент для імуноаналізу на вірус гепатиту с (варіанти), спосіб виявлення наявності антитіл (варіанти)
US5639856A (en) *	1993-09-13	1997-06-17	The Regents Of The University Of California	Semaphorin gene family
US5416197A (en) *	1993-10-15	1995-05-16	Trustees Of The University Of Pennsylvania	Antibodies which bind human collapsin
US5807806A (en) *	1997-06-12	1998-09-15	Nippon Soda Co., Ltd.	Benzoylpyrazole derivatives having specific substituents and herbicide

1993
- 1993-09-13 US US08/121,713 patent/US5639856A/en not_active Expired - Lifetime
1994
- 1994-09-13 ES ES94928057T patent/ES2173922T3/es not_active Expired - Lifetime
- 1994-09-13 CA CA002171638A patent/CA2171638C/en not_active Expired - Fee Related
- 1994-09-13 EP EP94928057A patent/EP0721342B1/en not_active Expired - Lifetime
- 1994-09-13 PT PT94928057T patent/PT721342E/pt unknown
- 1994-09-13 DE DE69430130T patent/DE69430130T2/de not_active Expired - Lifetime
- 1994-09-13 AU AU77240/94A patent/AU683494B2/en not_active Ceased
- 1994-09-13 JP JP50926195A patent/JP3544378B2/ja not_active Expired - Fee Related
- 1994-09-13 WO PCT/US1994/010151 patent/WO1995007706A1/en active IP Right Grant
- 1994-09-13 DK DK94928057T patent/DK0721342T3/da active
- 1994-09-13 AT AT94928057T patent/ATE214286T1/de active
1997
- 1997-04-08 US US08/835,268 patent/US5807826A/en not_active Expired - Lifetime
- 1997-04-08 US US08/833,391 patent/US6013781A/en not_active Expired - Fee Related
1998
- 1998-04-15 US US09/060,610 patent/US6344544B1/en not_active Expired - Fee Related
- 1998-04-15 US US09/060,692 patent/US5935865A/en not_active Expired - Lifetime
2002
- 2002-02-04 US US10/067,632 patent/US7153936B2/en not_active Expired - Fee Related
2006
- 2006-10-12 US US11/580,373 patent/US20070033669A1/en not_active Abandoned
2007
- 2007-06-14 US US11/763,394 patent/US20080312158A1/en not_active Abandoned

Also Published As

Publication number	Publication date
US20070033669A1 (en)	2007-02-08
ES2173922T3 (es)	2002-11-01
EP0721342B1 (en)	2002-03-13
JP3544378B2 (ja)	2004-07-21
CA2171638C (en)	2001-05-29
US7153936B2 (en)	2006-12-26
US5639856A (en)	1997-06-17
US6013781A (en)	2000-01-11
US5935865A (en)	1999-08-10
US5807826A (en)	1998-09-15
JPH09505725A (ja)	1997-06-10
EP0721342A4 (en)	1998-07-29
PT721342E (pt)	2002-09-30
US20030166849A1 (en)	2003-09-04
DE69430130D1 (de)	2002-04-18
US6344544B1 (en)	2002-02-05
AU7724094A (en)	1995-04-03
ATE214286T1 (de)	2002-03-15
CA2171638A1 (en)	1995-03-23
AU683494B2 (en)	1997-11-13
EP0721342A1 (en)	1996-07-17
US20080312158A1 (en)	2008-12-18
DE69430130T2 (de)	2002-08-22
WO1995007706A1 (en)	1995-03-23

Publication	Publication Date	Title
DK0721342T3 (da)	2002-07-15	Polypeptider fra Semaphorin genfamilien
DE746332T1 (de)	1997-04-10	Dna koheserial für einen rezeptor (y4) aus mensch für neuropeptid y/peptid yy/bauchspeichelabrüsen-polypeptid und seine verwendung
EP0530265A4 (en)	1993-06-16	Dna encoding human 5-ht 1d? receptors and uses thereof
DE69333776D1 (de)	2005-04-28	Dna codierend für den menschlichen 5-ht 1f rezeptor und ihre verwendung
AU735355C (en)	1998-11-11	Novel protein and method for producing the protein
CA2413857A1 (en)	2002-01-03	Pd-l2 molecules: pd-1 ligands and uses therefor
CA2174971A1 (en)	1995-05-18	Neural Axon Outgrowth Modulators
DE69233496D1 (de)	2005-05-04	Dna kodierend für den menschlichen 5-ht 1e-rezeptor und seine verwendungen
EP0789076A3 (en)	1999-04-14	G protein coupled receptor proteins, their production and use
EP0538395A4 (en)	1993-06-16	Nucleic acid sequences encoding a human dopamine d 1? receptor
Nakagawa et al.	1991	The use of the polymerase chain reaction to map CD4+ T cell epitopes
DE69734199D1 (de)	2005-10-20	Menschliches netrin-1