ATE179985T1 - Stabil solvate von avermectin verbindungen - Google Patents

Stabil solvate von avermectin verbindungen

Info

Publication number
ATE179985T1
ATE179985T1 AT94931307T AT94931307T ATE179985T1 AT E179985 T1 ATE179985 T1 AT E179985T1 AT 94931307 T AT94931307 T AT 94931307T AT 94931307 T AT94931307 T AT 94931307T AT E179985 T1 ATE179985 T1 AT E179985T1
Authority
AT
Austria
Prior art keywords
avermectin compounds
avermectin
compounds
disclosed
stable solvate
Prior art date
Application number
AT94931307T
Other languages
English (en)
Inventor
Joseph S Amato
Raymond Cvetovich
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE179985T1 publication Critical patent/ATE179985T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • External Artificial Organs (AREA)
AT94931307T 1993-10-08 1994-10-04 Stabil solvate von avermectin verbindungen ATE179985T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/133,494 US5380838A (en) 1993-10-08 1993-10-08 Stable solvates of avermectin compounds

Publications (1)

Publication Number Publication Date
ATE179985T1 true ATE179985T1 (de) 1999-05-15

Family

ID=22458871

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94931307T ATE179985T1 (de) 1993-10-08 1994-10-04 Stabil solvate von avermectin verbindungen

Country Status (10)

Country Link
US (1) US5380838A (de)
EP (1) EP0722454B1 (de)
JP (1) JP2938974B2 (de)
AT (1) ATE179985T1 (de)
AU (1) AU681916B2 (de)
CA (1) CA2171871C (de)
DE (1) DE69418469T2 (de)
ES (1) ES2131219T3 (de)
WO (1) WO1995010525A1 (de)
ZA (1) ZA947863B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9716567D0 (en) * 1997-08-05 1997-10-08 Pfizer Process
EP1043324B1 (de) 1997-11-12 2004-06-16 Mitsubishi Chemical Corporation Purinderivate und medikamente, welche dieselben als aktiven bestandteil enthalten
KR100747106B1 (ko) 1999-05-11 2007-08-08 미쯔비시 가가꾸 가부시끼가이샤 퓨린 유도체 이수화물, 이를 유효성분으로 함유하는 의약및 이의 제조 중간체
WO2004063147A1 (en) * 2003-01-10 2004-07-29 Novo Nordisk A/S Salts and solvates of glucagon antagonists

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
NZ188459A (en) * 1977-10-03 1982-09-07 Merck & Co Inc Derivatives of c-076 compounds and pesticidal compositions
US4206205A (en) * 1977-10-03 1980-06-03 Merck & Co., Inc. Monosaccharide and aglycone derivatives of C-076
PH15982A (en) * 1977-10-03 1983-05-18 Merck & Co Inc Selective hydrogenation producta of c-076 compounds and derivatives thereof
US4171314A (en) * 1977-12-19 1979-10-16 Merck & Co., Inc. 13-Halo and 13-deoxy C-076 compounds
US4734375A (en) * 1980-05-27 1988-03-29 Miles Laboratories, Inc. Ion specific test method
US4457920A (en) * 1981-09-03 1984-07-03 Merck & Co., Inc. 4a-Substituted avermectin compounds
US4657854A (en) * 1983-05-05 1987-04-14 Ivan Endre Modrovich Assay systems based on magnesium-responsive enzymes
DE3669515D1 (de) * 1985-09-13 1990-04-19 Biotechnolog Forschung Gmbh Makrozyklische antibiotika.
US4812400A (en) * 1986-07-14 1989-03-14 Steinman Gary D Process for measuring sodium levels in biological fluids
JPH0612999B2 (ja) * 1986-11-17 1994-02-23 関東化学株式会社 塩素イオン定量用試薬

Also Published As

Publication number Publication date
DE69418469D1 (de) 1999-06-17
EP0722454B1 (de) 1999-05-12
CA2171871A1 (en) 1995-04-20
US5380838A (en) 1995-01-10
ZA947863B (en) 1995-05-22
CA2171871C (en) 1999-08-03
DE69418469T2 (de) 1999-12-16
AU681916B2 (en) 1997-09-11
ES2131219T3 (es) 1999-07-16
JP2938974B2 (ja) 1999-08-25
AU8013094A (en) 1995-05-04
EP0722454A1 (de) 1996-07-24
WO1995010525A1 (en) 1995-04-20
JPH09503521A (ja) 1997-04-08

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Legal Events

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