ES2090083T3 - Derivados de cefalosporina, procedimiento para su preparacion y composicion antimicrobiana que contiene estos derivados. - Google Patents

Derivados de cefalosporina, procedimiento para su preparacion y composicion antimicrobiana que contiene estos derivados.

Info

Publication number
ES2090083T3
ES2090083T3 ES90125707T ES90125707T ES2090083T3 ES 2090083 T3 ES2090083 T3 ES 2090083T3 ES 90125707 T ES90125707 T ES 90125707T ES 90125707 T ES90125707 T ES 90125707T ES 2090083 T3 ES2090083 T3 ES 2090083T3
Authority
ES
Spain
Prior art keywords
elevated
derivatives
procedure
preparation
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90125707T
Other languages
English (en)
Inventor
Tetsuhiko Shirasaka
Hiroshi Ishikawa
Koichi Yasamura
Koichiro Jitsukawa
Sachio Toyama
Hidetsugu Tsubouchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2655990A external-priority patent/JPH03232892A/ja
Priority claimed from JP2171981A external-priority patent/JPH0459781A/ja
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ES2090083T3 publication Critical patent/ES2090083T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

SE SUMINISTRA UN DERIVADO DE CEFALOSPORINA REPRESENTADO POR LA FORMULA GENERAL (1): DONDE R ELEVADO 101, R ELEVADO 102, R ELEVADO 103 Y Y ELEVADO 101 SON COMO SE DEFINEN LA FORMULA GENERAL (2): DONDE R ELEVADO 201, R ELEVADO 202, Y R ELEVADO 203 SON COMO SE DEFINEN ARRIBA; LA FORMULA GENERAL (3): DONDE R ELEVADO 301, R ELEVADO 302, Y ELEVADO 301, Y ELEVADO 302 Y A ELEVADO 301 SON COMO SE DEFINEN; O SAL DE LAS FARMACEUTICAMENTE ACEPTABLES. EL COMPUESTO ES UTIL COMO UN INGREDIENTE ACTIVO EN AGENTES ANTIMICROBIANOS .
ES90125707T 1989-12-29 1990-12-28 Derivados de cefalosporina, procedimiento para su preparacion y composicion antimicrobiana que contiene estos derivados. Expired - Lifetime ES2090083T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP34004489 1989-12-29
JP2655990A JPH03232892A (ja) 1990-02-05 1990-02-05 セファロスポリン誘導体
JP9464890 1990-04-09
JP2171981A JPH0459781A (ja) 1990-06-28 1990-06-28 セファロスポリン誘導体

Publications (1)

Publication Number Publication Date
ES2090083T3 true ES2090083T3 (es) 1996-10-16

Family

ID=27458528

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90125707T Expired - Lifetime ES2090083T3 (es) 1989-12-29 1990-12-28 Derivados de cefalosporina, procedimiento para su preparacion y composicion antimicrobiana que contiene estos derivados.

Country Status (7)

Country Link
US (1) US5262411A (es)
EP (1) EP0435333B1 (es)
KR (1) KR910011865A (es)
CN (1) CN1052863A (es)
DE (1) DE69027286T2 (es)
DK (1) DK0435333T3 (es)
ES (1) ES2090083T3 (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5385897A (en) * 1985-08-09 1995-01-31 Roussel-Uclaf 4-thia-1-aza-bicyclo[4,2,0]oct-2-ene derivatives
FR2678273B1 (fr) * 1991-06-25 1995-03-03 Roussel Uclaf Nouvelles cephalosporines comportant un noyau 2-thia cepheme, leur procede de preparation, leur application comme medicaments, et les nouveaux intermediaires obtenus.
EP0544166A3 (en) * 1991-11-26 1993-11-03 Hoffmann La Roche Cephalosporinderivatives
DE69331047T2 (de) * 1992-01-22 2002-03-21 Pfizer 2-isocephem und -oxacephemderivate,verfahren zu deren herstellung, deren zwischenprodukte und verwendung als antibakterielle mittel
EP0579221A1 (en) * 1992-07-17 1994-01-19 Takeda Chemical Industries, Ltd. Cephem compounds, their production and use
AU3823595A (en) * 1994-09-30 1996-05-02 Chemfree Corporation Parts washing system
ZA9811445B (en) * 1997-12-19 1999-08-16 Alcon Lab Inc Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions.
US6566034B2 (en) 2000-09-11 2003-05-20 Agfa-Gevaert Photographic material containing a novel hydrazine type
EP1186946A1 (en) * 2000-09-11 2002-03-13 Agfa-Gevaert Photographic material containing a novel hydrazine type
US20040002600A1 (en) * 2002-06-20 2004-01-01 Orchid Chemicals And Pharmaceuticals Limited Process for the conversion of penam ring system to cepham ring system
CN101190922B (zh) * 2006-12-01 2010-06-02 山东轩竹医药科技有限公司 头孢菌素衍生物
US9242999B2 (en) 2011-06-27 2016-01-26 Shionogi & Co., Ltd. Cephem compound having pyridinium group
CN107586305A (zh) * 2017-06-23 2018-01-16 浙江惠迪森药业有限公司 一种β‑内酰胺类化合物羧基及羟基保护基脱除方法
CN110655526A (zh) * 2018-06-28 2020-01-07 中国科学院上海药物研究所 头孢菌素-铁载体轭合物及其制备方法和用途
CN111620893B (zh) * 2020-06-08 2021-12-14 重庆医药高等专科学校 C-3位四氢呋喃取代的头孢菌素-铁载体耦合物及其制备方法和应用
CN112409383A (zh) * 2020-11-30 2021-02-26 上海交通大学医学院 一种氨噻肟哌啶酮头孢菌素的制备及应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2559486B1 (fr) * 1984-02-13 1988-02-12 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation et leur application comme medicaments
EP0215435B1 (en) * 1985-09-09 1993-03-03 Otsuka Pharmaceutical Co., Ltd. 2-oxa-isocephem compounds, compositions containing same and processes for preparing same
FR2610630B2 (fr) * 1987-02-06 1989-05-26 Roussel Uclaf Nouveaux derives de l'acide 1-dethia 2-thia cephalosporanique, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les contenant
JPS63313788A (ja) * 1987-06-16 1988-12-21 Otsuka Pharmaceut Co Ltd セファロスポリン誘導体

Also Published As

Publication number Publication date
DE69027286D1 (de) 1996-07-11
DE69027286T2 (de) 1996-12-19
EP0435333B1 (en) 1996-06-05
KR910011865A (ko) 1991-08-07
EP0435333A2 (en) 1991-07-03
EP0435333A3 (en) 1992-01-29
DK0435333T3 (da) 1996-06-24
CN1052863A (zh) 1991-07-10
US5262411A (en) 1993-11-16

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