ATE177783T1 - Ein menschlicher t-zell rezeptor der protein g- gekoppelte rezeptor familie - Google Patents

Ein menschlicher t-zell rezeptor der protein g- gekoppelte rezeptor familie

Info

Publication number
ATE177783T1
ATE177783T1 AT94906667T AT94906667T ATE177783T1 AT E177783 T1 ATE177783 T1 AT E177783T1 AT 94906667 T AT94906667 T AT 94906667T AT 94906667 T AT94906667 T AT 94906667T AT E177783 T1 ATE177783 T1 AT E177783T1
Authority
AT
Austria
Prior art keywords
human
receptor
cell receptor
protein
nucleotide sequences
Prior art date
Application number
AT94906667T
Other languages
English (en)
Inventor
Jeffrey Herbert Hanke
Kevin Thomas Ogborne
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE177783T1 publication Critical patent/ATE177783T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2207/00—Modified animals
    • A01K2207/15—Humanized animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00—Animals characterised by species
    • A01K2227/10—Mammal
    • A01K2227/105—Murine
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0331—Animal model for proliferative diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0381—Animal model for diseases of the hematopoietic system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT94906667T 1993-04-09 1994-01-28 Ein menschlicher t-zell rezeptor der protein g- gekoppelte rezeptor familie ATE177783T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4653193A 1993-04-09 1993-04-09

Publications (1)

Publication Number Publication Date
ATE177783T1 true ATE177783T1 (de) 1999-04-15

Family

ID=21943934

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94906667T ATE177783T1 (de) 1993-04-09 1994-01-28 Ein menschlicher t-zell rezeptor der protein g- gekoppelte rezeptor familie

Country Status (9)

Country Link
EP (1) EP0692026B1 (de)
JP (1) JPH08506246A (de)
AT (1) ATE177783T1 (de)
CA (1) CA2159813A1 (de)
DE (1) DE69417223T2 (de)
DK (1) DK0692026T3 (de)
ES (1) ES2129120T3 (de)
GR (1) GR3030152T3 (de)
WO (1) WO1994024282A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996035785A2 (en) * 1995-05-11 1996-11-14 Karo Bio Ab Transgenic animals having a defective thyroid hormone receptor beta gene
US6258527B1 (en) 1996-05-20 2001-07-10 The Aaron Diamond Aids Research Center Methods of identifying g-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
US5939320A (en) * 1996-05-20 1999-08-17 New York University G-coupled receptors associated with macrophage-trophic HIV, and diagnostic and therapeutic uses thereof
US6057102A (en) * 1996-08-08 2000-05-02 The Aaron Diamond Aids Research Center HIV coreceptor mutants
US6140064A (en) 1996-09-10 2000-10-31 Theodor-Kocher Institute Method of detecting or identifying ligands, inhibitors or promoters of CXC chemokine receptor 3
RU2121718C1 (ru) 1998-02-19 1998-11-10 Яков Шоел-Берович Ровнер Портативная музыкальная система для караоке и картридж для нее
WO2003000893A2 (en) * 2001-06-26 2003-01-03 Decode Genetics Ehf. Nucleic acids encoding g protein-coupled receptors
US7994298B2 (en) 2004-09-24 2011-08-09 Trustees Of Dartmouth College Chimeric NK receptor and methods for treating cancer
WO2011059836A2 (en) 2009-10-29 2011-05-19 Trustees Of Dartmouth College T cell receptor-deficient t cell compositions
US9273283B2 (en) 2009-10-29 2016-03-01 The Trustees Of Dartmouth College Method of producing T cell receptor-deficient T cells expressing a chimeric receptor
WO2013033626A2 (en) 2011-08-31 2013-03-07 Trustees Of Dartmouth College Nkp30 receptor targeted therapeutics
ES2719495T3 (es) 2012-05-07 2019-07-10 Dartmouth College Anticuerpo dirigido contra b7-h6, proteínas de fusión, y métodos de uso de los mismos

Also Published As

Publication number Publication date
DE69417223D1 (de) 1999-04-22
GR3030152T3 (en) 1999-08-31
JPH08506246A (ja) 1996-07-09
DK0692026T3 (da) 1999-09-27
DE69417223T2 (de) 1999-07-08
EP0692026B1 (de) 1999-03-17
WO1994024282A1 (en) 1994-10-27
CA2159813A1 (en) 1994-10-27
EP0692026A1 (de) 1996-01-17
ES2129120T3 (es) 1999-06-01

Similar Documents

Publication Publication Date Title
ATE189607T1 (de) Dna codierend für einen menschlichen neuropeptid y/peptid yy/pankreaspolypeptid-rezeptor (y4) und seine verwendung
ATE253111T1 (de) Für den capsaicin rezeptor kodierende nukleinsäuresequenzen und dem capsaicin rezeptor ähnliche polypeptide und ihre verwendung
DE69832178D1 (de) Trail bindender rezeptor
ATE177783T1 (de) Ein menschlicher t-zell rezeptor der protein g- gekoppelte rezeptor familie
NO20020861D0 (no) PD-1, en reseptor for B7-4, og anvendelser derav
CA2174529A1 (en) Dna encoding a hypothalamic atypical neuropeptide y/peptide yy receptor (y5) and uses thereof
DK1011704T3 (da) Tumornekrose-faktor-receptor-afledte peptid-analiger
ES2187946T3 (es) Uso de interleucina-15.
AU1208497A (en) Ligand polypeptides for the g-protein-coupled receptor protein, their production and use
DE69842225D1 (de) Zusammensetzung, umfassend einen Antikörper, der selektiv an ein cysteinreiches sekretiertes Protein (CRSP) bindet
TW272197B (de)
AU3618095A (en) Alk-7 (activin like kinase), a serine threonine kinase receptor
WO2002102839A3 (en) Novel g-protein coupled receptors and dna sequences thereof
EP0992584A3 (de) Gereinigte Säugetier FLT3 Liganden und deren Agonisten und Antagonisten
WO2001000673A8 (en) Membrane-associated and secreted proteins and uses thereof
PT773999E (pt) Receptor orfao or-1 pertencente a familia de receptores nucleares
DK1071779T3 (da) Patched-2-protein fra hvirveldyr
EP0331184A3 (de) Peptid-Gegenwerte von Nichtpeptiden und Verfahren zum Entwurf dafür
WO2003087331A3 (en) Polyvalent cation-sensing receptor in atlantic salmon
EA199900663A1 (ru) Новые белки, связывающиеся с рецептором 1 интерферона, кодирующая их днк и способы модуляции клеточного ответа на интерфероны
WO2000039150A3 (en) Secreted proteins and uses thereof
WO2000050442A3 (en) Secreted proteins and uses thereof
MXPA04000437A (es) Un nuevo receptor acoplado a proteina g, gave8.
WO2002095056A3 (en) A novel g protein-coupled receptor, gave1
Geuder et al. MG-associated thymoma-protein with an AChR-epitope. Molecular genetic characterization by sequence analysis of the cDNA

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee