ATE172880T1 - Verwendung von monoklonalen anti-tnf-antikörpern für die behandlung von bakteriellen meningitiden - Google Patents
Verwendung von monoklonalen anti-tnf-antikörpern für die behandlung von bakteriellen meningitidenInfo
- Publication number
- ATE172880T1 ATE172880T1 AT93113072T AT93113072T ATE172880T1 AT E172880 T1 ATE172880 T1 AT E172880T1 AT 93113072 T AT93113072 T AT 93113072T AT 93113072 T AT93113072 T AT 93113072T AT E172880 T1 ATE172880 T1 AT E172880T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- bacterial meningitis
- monoclonal anti
- tnf antibodies
- bacterial
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US93793992A | 1992-08-28 | 1992-08-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE172880T1 true ATE172880T1 (de) | 1998-11-15 |
Family
ID=25470604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT93113072T ATE172880T1 (de) | 1992-08-28 | 1993-08-16 | Verwendung von monoklonalen anti-tnf-antikörpern für die behandlung von bakteriellen meningitiden |
Country Status (6)
Country | Link |
---|---|
US (1) | US5616321A (de) |
EP (1) | EP0585705B1 (de) |
AT (1) | ATE172880T1 (de) |
DE (1) | DE69321909T2 (de) |
DK (1) | DK0585705T3 (de) |
ES (1) | ES2121907T3 (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6284471B1 (en) | 1991-03-18 | 2001-09-04 | New York University Medical Center | Anti-TNFa antibodies and assays employing anti-TNFa antibodies |
US6277969B1 (en) | 1991-03-18 | 2001-08-21 | New York University | Anti-TNF antibodies and peptides of human tumor necrosis factor |
US7192584B2 (en) | 1991-03-18 | 2007-03-20 | Centocor, Inc. | Methods of treating psoriasis with anti-TNF antibodies |
PT614984E (pt) † | 1993-03-05 | 2001-12-28 | Bayer Ag | Anticorpos humanos anti-tnf |
US6090382A (en) | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
CA2868614A1 (en) | 2001-06-08 | 2002-12-08 | Abbott Laboratories (Bermuda) Ltd. | Methods of administering anti-tnf.alpha. antibodies |
TWI327597B (en) | 2001-08-01 | 2010-07-21 | Centocor Inc | Anti-tnf antibodies, compositions, methods and uses |
US20030206898A1 (en) | 2002-04-26 | 2003-11-06 | Steven Fischkoff | Use of anti-TNFalpha antibodies and another drug |
US20040033228A1 (en) | 2002-08-16 | 2004-02-19 | Hans-Juergen Krause | Formulation of human antibodies for treating TNF-alpha associated disorders |
MY150740A (en) | 2002-10-24 | 2014-02-28 | Abbvie Biotechnology Ltd | Low dose methods for treating disorders in which tnf? activity is detrimental |
WO2004041865A2 (en) | 2002-11-08 | 2004-05-21 | Ablynx N.V. | Stabilized single domain antibodies |
ES2347239T3 (es) * | 2002-12-02 | 2010-10-27 | Amgen Fremont Inc. | Anticuerpos dirigidos al factor de necrosis tumoral y usos de los mismos. |
US7101978B2 (en) * | 2003-01-08 | 2006-09-05 | Applied Molecular Evolution | TNF-α binding molecules |
JP4484664B2 (ja) * | 2003-11-27 | 2010-06-16 | キヤノン株式会社 | 記録ヘッドカートリッジ |
US7435799B2 (en) * | 2004-01-08 | 2008-10-14 | Applied Molecular Evolution | TNF-α binding molecules |
TW201705980A (zh) | 2004-04-09 | 2017-02-16 | 艾伯維生物技術有限責任公司 | 用於治療TNFα相關失調症之多重可變劑量療法 |
CN101500607B (zh) | 2005-05-16 | 2013-11-27 | 阿布维生物技术有限公司 | TNFα抑制剂治疗腐蚀性多关节炎的用途 |
EP1888640B1 (de) | 2005-05-18 | 2012-03-14 | Ablynx N.V. | Verbesserte nanokörper gegen tumornekrosefaktor-alpha |
SG170837A1 (en) | 2006-04-05 | 2011-05-30 | Abbott Biotech Ltd | Antibody purification |
US9605064B2 (en) | 2006-04-10 | 2017-03-28 | Abbvie Biotechnology Ltd | Methods and compositions for treatment of skin disorders |
WO2012149197A2 (en) | 2011-04-27 | 2012-11-01 | Abbott Laboratories | Methods for controlling the galactosylation profile of recombinantly-expressed proteins |
JP6175431B2 (ja) | 2011-06-20 | 2017-08-02 | アイカーン スクール オブ メディシン アット マウント サイナイ | ムコ多糖症およびその他のリソソーム障害に対する抗tnf療法 |
US9067990B2 (en) | 2013-03-14 | 2015-06-30 | Abbvie, Inc. | Protein purification using displacement chromatography |
WO2013158273A1 (en) | 2012-04-20 | 2013-10-24 | Abbvie Inc. | Methods to modulate c-terminal lysine variant distribution |
US9334319B2 (en) | 2012-04-20 | 2016-05-10 | Abbvie Inc. | Low acidic species compositions |
US9512214B2 (en) | 2012-09-02 | 2016-12-06 | Abbvie, Inc. | Methods to control protein heterogeneity |
AU2014215639B2 (en) | 2013-01-25 | 2017-03-23 | Thymon, Llc | Compositions for selective reduction of circulating bioactive soluble TNF and methods for treating TNF-mediated disease |
SG11201507230PA (en) | 2013-03-12 | 2015-10-29 | Abbvie Inc | Human antibodies that bind human tnf-alpha and methods of preparing the same |
WO2014151878A2 (en) | 2013-03-14 | 2014-09-25 | Abbvie Inc. | Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides |
US9017687B1 (en) | 2013-10-18 | 2015-04-28 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same using displacement chromatography |
EP2803365A1 (de) | 2013-05-14 | 2014-11-19 | Commissariat A L'energie Atomique Et Aux Energies Alternatives | Verwendung von Clonazepam in Verbindung mit Antibiotika bei der Behandlung von bakteriell verursachter Meningitis |
US9598667B2 (en) | 2013-10-04 | 2017-03-21 | Abbvie Inc. | Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins |
US9181337B2 (en) | 2013-10-18 | 2015-11-10 | Abbvie, Inc. | Modulated lysine variant species compositions and methods for producing and using the same |
US9085618B2 (en) | 2013-10-18 | 2015-07-21 | Abbvie, Inc. | Low acidic species compositions and methods for producing and using the same |
WO2015073884A2 (en) | 2013-11-15 | 2015-05-21 | Abbvie, Inc. | Glycoengineered binding protein compositions |
WO2016160976A2 (en) | 2015-03-30 | 2016-10-06 | Abbvie Inc. | Monovalent tnf binding proteins |
EP3078675A1 (de) | 2015-04-10 | 2016-10-12 | Ares Trading S.A. | Induktionsdosierschema zur behandlung von krankheiten die von tnf alpha verursacht sind |
US10465003B2 (en) | 2016-02-05 | 2019-11-05 | Janssen Biotech, Inc. | Anti-TNF antibodies, compositions, methods and use for the treatment or prevention of type 1 diabetes |
JOP20190162A1 (ar) | 2016-12-30 | 2019-06-27 | Biocad Joint Stock Co | تركيبة صيدلانية مائية من جسم مضاد لـ tnf? أحادي النسيلة معاود الارتباط الجيني |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL73883A (en) * | 1984-12-20 | 1990-12-23 | Yeda Res & Dev | Monoclonal antibodies against tnf-alpha,hybridomas producing them and method for the purification of tnf-alpha |
DE3631229A1 (de) * | 1986-09-13 | 1988-03-24 | Basf Ag | Monoklonale antikoerper gegen humanen tumornekrosefaktor (tnf) und deren verwendung |
JP2647427B2 (ja) * | 1987-04-24 | 1997-08-27 | 帝人株式会社 | 被検者の病態の判定のための検出方法、モノクロ−ナル抗体および検出キット |
GB8806339D0 (en) * | 1988-03-17 | 1988-04-13 | Hoffmann La Roche | Monoclonal antibodies |
NZ229922A (en) * | 1988-07-18 | 1992-04-28 | Chiron Corp | Monoclonal antibodies specifically binding cachectin (tumor necrosis factor) and compositions |
EP0355067A1 (de) * | 1988-08-19 | 1990-02-21 | Celltech Limited | Arzneimittel gegen bösartige Gewebeneubildung |
US5360716A (en) * | 1988-10-24 | 1994-11-01 | Otsuka Pharmaceutical Co., Ltd. | Human tumor necrosis factor αspecific monoclonal antibody and method for detecting human tumor necrosis factor α |
GB8905400D0 (en) * | 1989-03-09 | 1989-04-19 | Jonker Margreet | Medicaments |
GB8921123D0 (en) * | 1989-09-19 | 1989-11-08 | Millar Ann B | Treatment of ards |
JPH06500323A (ja) * | 1990-08-27 | 1994-01-13 | ペプチド テクノロジィ リミテッド | ウイルス性感染の治療方法 |
GB9028123D0 (en) * | 1990-12-28 | 1991-02-13 | Erba Carlo Spa | Monoclonal antibodies against human tumor necrosis factor alpha |
DE07006112T1 (de) * | 1991-03-18 | 2010-01-21 | New York University | Monoklonale und chimäre Antikörper gegen humanen Tumornekrosefaktor |
AU5152293A (en) * | 1992-10-08 | 1994-05-09 | Kennedy Institute Of Rheumatology, The | Treatment of autoimmune and inflammatory disorders |
GB9225448D0 (en) * | 1992-12-04 | 1993-01-27 | Erba Carlo Spa | Improved synthesis of polymer bioactive conjugates |
EP0732938A4 (de) * | 1993-12-01 | 1997-03-19 | Unisearch Ltd | Verfahren zur behandlung von intestinalen störungen |
-
1993
- 1993-08-16 ES ES93113072T patent/ES2121907T3/es not_active Expired - Lifetime
- 1993-08-16 AT AT93113072T patent/ATE172880T1/de active
- 1993-08-16 DK DK93113072T patent/DK0585705T3/da active
- 1993-08-16 EP EP93113072A patent/EP0585705B1/de not_active Expired - Lifetime
- 1993-08-16 DE DE69321909T patent/DE69321909T2/de not_active Expired - Lifetime
-
1995
- 1995-03-23 US US08/410,006 patent/US5616321A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69321909T2 (de) | 1999-04-01 |
DE69321909D1 (de) | 1998-12-10 |
DK0585705T3 (da) | 1999-07-26 |
ES2121907T3 (es) | 1998-12-16 |
EP0585705B1 (de) | 1998-11-04 |
EP0585705A1 (de) | 1994-03-09 |
US5616321A (en) | 1997-04-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE172880T1 (de) | Verwendung von monoklonalen anti-tnf-antikörpern für die behandlung von bakteriellen meningitiden | |
DE68927671D1 (de) | Produkte zur Behandlung des Endotoxin -Schocks bei einem Säugetier | |
ATE249518T1 (de) | Humanisierter antikörper gegen cd18 | |
ATE117434T1 (de) | Gefriergetrocknete zusammensetzung, die ein mit meerrettichperoxydase markiertes fab'-fragment eines gegen menschliches beta-interferon gerichteten antikörpers und trehalose enthält; eia kit, der diese zusammensetzung enthält. | |
GR3026750T3 (en) | Inhibition of nitric oxide-mediated hypotension and septic shock with iron-containing hemoprotein. | |
DE69221501T2 (de) | Verfahren zum vermindern von durch medizinische vorrichtungen bedingten infektionen | |
DE69733960D1 (de) | Verwendung von antikörpen gegen cd45ro leukozytenantigen zur immunmodulation | |
ATE155043T1 (de) | Behandlung von autoimmun- und entzundungskrankheiten | |
DE69424915T2 (de) | Verwendung von 1-2-4-Benzotriazinoxiden zur Herstellung eines Arzneimittels zur Behandlung von Tumoren | |
DE68921979T2 (de) | Antikörper für die antilymphozyten-antikörpertherapie. | |
DE69426767D1 (de) | Anti idiotypische Antikörper gegen Gonococcen und diese verwendende Verfahren und Zusammensetzungen. | |
EA200400930A1 (ru) | Блокирующее моноклональное антитело к vla-1 или его применение для лечения воспалительных заболеваний | |
AU2456888A (en) | Monoclonal antibodies specific for HIV and hybridomas for their production | |
RU93004678A (ru) | Противомикробные производные карбапенема, способы их получения и применение | |
DK0792162T3 (da) | Anvendelse af antistoffer til blokering af virkningerne af grampositive bakterier og mycobakterier | |
ATE28214T1 (de) | Malolaktisches gaerungsverfahren. | |
NO934655L (no) | Legemiddel for gram-positive sykdommer i akvatiske arter | |
DE3773059D1 (de) | Ester von salsalat mit guajakol zur behandlung von phlogistischen bronchopneumopathien. | |
DE69527868T2 (de) | Monoklonaler Antikörper gegen den tumorzytotoxischen Faktor II (TCF-II) | |
DE59008759D1 (de) | Verwendung von interleukin-2 zur behandlung der endotoxinämie. | |
ATE33842T1 (de) | Immuninterferon und verfahren zu seiner reinigung. | |
EP0321094A3 (de) | Behandlung von Faktor-VIII-Inhibitoren | |
DE68924963T2 (de) | Zusammensetzungen und Methoden zur Behandlung und Vorbeugung von Gram-Negativen-Infektionen. | |
EA200101271A1 (ru) | Блокирующее моноклональное антитело к vla-1 и его применение для лечения воспалительных заболеваний | |
TR199700791T1 (xx) | Kendiliğinden bağışıklığı olan hastalıkların ve allograft rejeksiyonun tedavisi için LCK SH2 spesifik bileşimlerinin kullanılması. |