ATE172735T1 - Tropyl 7-azaindol-3-ylcarboxamide als antitussivum - Google Patents

Tropyl 7-azaindol-3-ylcarboxamide als antitussivum

Info

Publication number
ATE172735T1
ATE172735T1 AT94921777T AT94921777T ATE172735T1 AT E172735 T1 ATE172735 T1 AT E172735T1 AT 94921777 T AT94921777 T AT 94921777T AT 94921777 T AT94921777 T AT 94921777T AT E172735 T1 ATE172735 T1 AT E172735T1
Authority
AT
Austria
Prior art keywords
pct
azaindol
antitussive
tropyl
ylcarboxamide
Prior art date
Application number
AT94921777T
Other languages
English (en)
Inventor
Marco Mantovanini
Gabriella Melillo
Luisa Daffonchio
Original Assignee
Dompe Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Spa filed Critical Dompe Spa
Application granted granted Critical
Publication of ATE172735T1 publication Critical patent/ATE172735T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT94921777T 1993-08-05 1994-08-04 Tropyl 7-azaindol-3-ylcarboxamide als antitussivum ATE172735T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT93MI001780A IT1265057B1 (it) 1993-08-05 1993-08-05 Tropil 7-azaindolil-3-carbossiamidi

Publications (1)

Publication Number Publication Date
ATE172735T1 true ATE172735T1 (de) 1998-11-15

Family

ID=11366781

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94921777T ATE172735T1 (de) 1993-08-05 1994-08-04 Tropyl 7-azaindol-3-ylcarboxamide als antitussivum

Country Status (12)

Country Link
US (1) US5750536A (de)
EP (1) EP0712408B1 (de)
AT (1) ATE172735T1 (de)
AU (1) AU683524B2 (de)
CA (1) CA2172616C (de)
DE (1) DE69414256T2 (de)
DK (1) DK0712408T3 (de)
ES (1) ES2126766T3 (de)
HK (1) HK1011359A1 (de)
IT (1) IT1265057B1 (de)
WO (1) WO1995004742A1 (de)
ZA (1) ZA945817B (de)

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IT1303123B1 (it) 1998-10-13 2000-10-30 Rotta Research Lab Derivati basici di benz(e)isoindol-1-oni e pirrolo(3,4-c)chinolin-1-oni ad attivita' 5ht3 antagonista, loro preparazione ed
US6476034B2 (en) 2000-02-22 2002-11-05 Bristol-Myers Squibb Company Antiviral azaindole derivatives
US20040110785A1 (en) 2001-02-02 2004-06-10 Tao Wang Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives
US20030207910A1 (en) 2001-02-02 2003-11-06 Tao Wang Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives
US6825201B2 (en) 2001-04-25 2004-11-30 Bristol-Myers Squibb Company Indole, azaindole and related heterocyclic amidopiperazine derivatives
AR036040A1 (es) * 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
KR100614900B1 (ko) 2001-10-02 2006-08-25 파마시아 앤드 업존 캄파니 엘엘씨 질병의 치료를 위한 아자비시클릭-치환된 융합-헤테로아릴화합물
WO2003028724A1 (en) * 2001-10-04 2003-04-10 Smithkline Beecham Corporation Chk1 kinase inhibitors
US20030236277A1 (en) 2002-02-14 2003-12-25 Kadow John F. Indole, azaindole and related heterocyclic pyrrolidine derivatives
EP1476448A2 (de) * 2002-02-19 2004-11-17 PHARMACIA & UPJOHN COMPANY Azabicyclische verbindungen zur behandlung von erkrankungen
AU2003219690A1 (en) 2002-02-19 2003-09-09 Pharmacia And Upjohn Company Fused bicyclic-n-bridged-heteroaromatic carboxamides for the treatment of disease
US7037913B2 (en) 2002-05-01 2006-05-02 Bristol-Myers Squibb Company Bicyclo 4.4.0 antiviral derivatives
US7348337B2 (en) 2002-05-28 2008-03-25 Bristol-Myers Squibb Company Indole, azaindole and related heterocyclic 4-alkenyl piperidine amides
US6900206B2 (en) 2002-06-20 2005-05-31 Bristol-Myers Squibb Company Indole, azaindole and related heterocyclic sulfonylureido piperazine derivatives
EP1562959A2 (de) * 2002-11-01 2005-08-17 Pharmacia & Upjohn Company LLC Verbindungen, welche sowohl alpha7 nachr-agonisten als auch 5ht-antagonisten sind, für die behandlung von erkrankungen des zns
US20050075364A1 (en) 2003-07-01 2005-04-07 Kap-Sun Yeung Indole, azaindole and related heterocyclic N-substituted piperazine derivatives
US20050124623A1 (en) 2003-11-26 2005-06-09 Bender John A. Diazaindole-dicarbonyl-piperazinyl antiviral agents
PT1696920E (pt) 2003-12-19 2015-01-14 Plexxikon Inc Compostos e métodos para o desenvolvimento de moduladores de ret
DE602005024677D1 (de) * 2004-04-22 2010-12-23 Memory Pharm Corp Indole, 1h-indazole, 1,2-benzisoxazole, 1,2-benzoisothiazole, deren herstellung und verwendungen
US7498342B2 (en) 2004-06-17 2009-03-03 Plexxikon, Inc. Compounds modulating c-kit activity
US20060100432A1 (en) 2004-11-09 2006-05-11 Matiskella John D Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione
PE20071159A1 (es) * 2005-10-31 2007-11-30 Schering Corp Derivados de tropano 3-monosustituido como ligandos de receptores de nociceptina
US7851476B2 (en) 2005-12-14 2010-12-14 Bristol-Myers Squibb Company Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine
US7807671B2 (en) 2006-04-25 2010-10-05 Bristol-Myers Squibb Company Diketo-piperazine and piperidine derivatives as antiviral agents
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
WO2009012283A1 (en) 2007-07-17 2009-01-22 Plexxikon Inc. Compounds and methods for kinase modulation, and indications therefor
MX349923B (es) 2009-04-03 2017-08-21 Hoffmann La Roche Composiciones del ácido propano-1-sulfónico {3-[5-(4-cloro-fenil)- 1h-pirrolo [2,3-b]-piridina-3-carbonil]-2,4-difluoro-fenil]-amida y el uso de las mismas.
ES2633317T3 (es) 2009-11-06 2017-09-20 Plexxikon, Inc. Compuestos y métodos para la modulación de quinasas, e indicaciones para ello
PT2672967T (pt) 2011-02-07 2018-12-07 Plexxikon Inc Compostos e métodos de modulação da quinase e suas indicações
AR085279A1 (es) 2011-02-21 2013-09-18 Plexxikon Inc Formas solidas de {3-[5-(4-cloro-fenil)-1h-pirrolo[2,3-b]piridina-3-carbonil]-2,4-difluor-fenil}-amida del acido propano-1-sulfonico
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0421681A (ja) * 1990-05-14 1992-01-24 Fujisawa Pharmaceut Co Ltd ピロロピリジン誘導体
US5260303A (en) * 1991-03-07 1993-11-09 G. D. Searle & Co. Imidazopyridines as serotonergic 5-HT3 antagonists
IT1255467B (it) * 1992-07-29 1995-11-02 Dompe Farmaceutici Spa Ammidi acriliche farmacologicamente attive
JPH09221681A (ja) * 1996-02-16 1997-08-26 Mitsui Petrochem Ind Ltd プラスチックの油化方法

Also Published As

Publication number Publication date
DK0712408T3 (da) 1999-07-12
CA2172616A1 (en) 1995-02-16
IT1265057B1 (it) 1996-10-28
DE69414256T2 (de) 1999-06-02
AU1318295A (en) 1995-02-28
HK1011359A1 (en) 1999-07-09
DE69414256D1 (de) 1998-12-03
ZA945817B (en) 1995-03-10
EP0712408A1 (de) 1996-05-22
AU683524B2 (en) 1997-11-13
US5750536A (en) 1998-05-12
EP0712408B1 (de) 1998-10-28
ES2126766T3 (es) 1999-04-01
WO1995004742A1 (en) 1995-02-16
ITMI931780A0 (it) 1993-08-05
ITMI931780A1 (it) 1995-02-05
CA2172616C (en) 2001-05-29

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee