ATE154636T1 - Dopamin-rezeptoren und gene - Google Patents
Dopamin-rezeptoren und geneInfo
- Publication number
- ATE154636T1 ATE154636T1 AT90901227T AT90901227T ATE154636T1 AT E154636 T1 ATE154636 T1 AT E154636T1 AT 90901227 T AT90901227 T AT 90901227T AT 90901227 T AT90901227 T AT 90901227T AT E154636 T1 ATE154636 T1 AT E154636T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- well
- dopamine receptor
- labeled
- genes
- Prior art date
Links
- 108050004812 Dopamine receptor Proteins 0.000 title abstract 2
- 102000015554 Dopamine receptor Human genes 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 101150049660 DRD2 gene Proteins 0.000 abstract 1
- 108020004711 Nucleic Acid Probes Proteins 0.000 abstract 1
- 239000002853 nucleic acid probe Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/286—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against neuromediator receptors, e.g. serotonin receptor, dopamine receptor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Plant Pathology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27337388A | 1988-11-18 | 1988-11-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE154636T1 true ATE154636T1 (de) | 1997-07-15 |
Family
ID=23043636
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90901227T ATE154636T1 (de) | 1988-11-18 | 1989-11-20 | Dopamin-rezeptoren und gene |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0447483B1 (de) |
JP (3) | JP3018045B2 (de) |
AT (1) | ATE154636T1 (de) |
DE (1) | DE68928137T2 (de) |
ES (1) | ES2104599T3 (de) |
WO (1) | WO1990005780A1 (de) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3931841A1 (de) * | 1989-09-23 | 1991-04-04 | Basf Ag | Dopamin-d2-rezeptor |
WO1991012339A2 (en) * | 1990-02-07 | 1991-08-22 | Board Of Regents, The University Of Texas System | Allelic association of the human dopamine (d2) receptor gene in compulsive disorders such as alcoholism |
WO1991018005A1 (en) * | 1990-05-14 | 1991-11-28 | Duke University | Cloned genes encoding the d1 dopamine receptor |
AU8403191A (en) * | 1990-07-06 | 1992-02-04 | United States of America, as represented by the Secretary, U.S. Department of Commerce, The | A cdna encoding the rat d1 dopamine receptor linked to adenylyl cyclase activation and expression product |
AU8427291A (en) | 1990-07-10 | 1992-02-04 | Neurogenetic Corporation | Nucleic acid sequences encoding a human dopamine d1 receptor |
ES2157197T3 (es) * | 1990-09-13 | 2001-08-16 | Univ Duke | Expresion de receptores acoplados a una proteina g en levadura. |
US5245011A (en) * | 1991-04-16 | 1993-09-14 | Duke University | Aqueous solution containing D1B dopamine receptor |
US5215915A (en) * | 1991-04-16 | 1993-06-01 | Duke University | Cloned gene encoding rat d1b dopamine receptor |
WO1994013303A1 (en) * | 1992-12-14 | 1994-06-23 | Start Technology Partnership | Administration of oligonucleotides antisense to dopamine receptor mrna for diagnosis and treatment of neurological pathologies |
US20030054402A1 (en) | 1993-03-31 | 2003-03-20 | Cadus Pharmaceutical Corporation | Methods and compositions for identifying receptor effectors |
US6100042A (en) | 1993-03-31 | 2000-08-08 | Cadus Pharmaceutical Corporation | Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor |
US7235648B1 (en) | 1993-03-31 | 2007-06-26 | Cadus Technologies, Inc. | Yeast cells engineered to produce pheromone system protein surrogates, and uses therefor |
US6255059B1 (en) | 1993-03-31 | 2001-07-03 | Cadus Pharmaceutical Corporation | Methods for identifying G protein coupled receptor effectors |
AU1176095A (en) * | 1993-11-10 | 1995-05-29 | University Of British Columbia, The | Method of treatment using, process of preparing, and composition comprising a recombinant hsv-1 |
FR2733514A1 (fr) * | 1995-04-26 | 1996-10-31 | Inst Nat Sante Rech Med | Animal transgenique non humain dans lequel l'expression du recepteur d2 est modifiee |
US5686255A (en) * | 1995-05-24 | 1997-11-11 | Deth; Richard C. | Compositions and methods for diagnosing schizophrenia |
US5738998A (en) * | 1995-05-24 | 1998-04-14 | Deth; Richard C. | Compositions and methods for diagnosing schizophrenia |
US5945302A (en) * | 1996-04-05 | 1999-08-31 | Genetics Institute, Inc. | Polynucleotides encoding secreted proteins |
US5654173A (en) * | 1996-08-23 | 1997-08-05 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
US5728819A (en) * | 1996-08-02 | 1998-03-17 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
US5723315A (en) * | 1996-08-23 | 1998-03-03 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
US5708157A (en) * | 1996-07-26 | 1998-01-13 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
US5965388A (en) * | 1996-07-09 | 1999-10-12 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
US5985602A (en) * | 1996-08-14 | 1999-11-16 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
WO1998001469A2 (en) * | 1996-06-19 | 1998-01-15 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
EP0912735A2 (de) * | 1996-07-09 | 1999-05-06 | Genetics Institute, Inc. | Sekretierte proteine und polynucleotide die für diese kodieren |
AU3962497A (en) * | 1996-07-26 | 1998-02-20 | Genetics Institute Inc. | Secreted proteins and polynucleotides encoding them |
JP2001501456A (ja) * | 1996-07-26 | 2001-02-06 | ジェネティックス・インスチチュート・インコーポレーテッド | 分泌蛋白およびそれらをコードするポリヌクレオチド |
WO1998004696A1 (en) * | 1996-07-26 | 1998-02-05 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
JP2002516563A (ja) * | 1996-08-02 | 2002-06-04 | ジェネティックス・インスチチュート・インコーポレーテッド | 分泌蛋白およびそれらをコードするポリヌクレオチド |
JP2000516816A (ja) * | 1996-08-23 | 2000-12-19 | ジェネティックス・インスチチュート・インコーポレーテッド | 分泌蛋白およびそれらをコードするポリヌクレオチド |
AU4809497A (en) * | 1996-10-04 | 1998-04-24 | Genetics Institute Inc. | Secreted proteins |
WO1998014575A1 (en) * | 1996-10-04 | 1998-04-09 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them________________________________________________________________________________________________________________________________________________ |
WO1998014576A2 (en) * | 1996-10-04 | 1998-04-09 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
WO1998017687A2 (en) * | 1996-10-25 | 1998-04-30 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
JP2002515753A (ja) * | 1996-11-01 | 2002-05-28 | ジェネティックス・インスティテュート・インコーポレイテッド | 分泌蛋白およびそれらをコードしているポリヌクレオチド |
EP0950102A1 (de) * | 1996-11-06 | 1999-10-20 | Genetics Institute, Inc. | Sekretierte proteine und kodierende polynucleotide dafür |
CA2270873A1 (en) * | 1996-11-15 | 1998-05-22 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
AU5516498A (en) * | 1996-12-06 | 1998-06-29 | Genetics Institute Inc. | Secreted proteins and polynucleotides encoding them |
AU6022198A (en) * | 1997-01-09 | 1998-08-03 | Genetics Institute Inc. | Secreted proteins and polynucleotides encoding them |
EP1007660A2 (de) * | 1997-01-13 | 2000-06-14 | Genetics Institute, Inc. | Sekretierte proteine und dafür kodierende polynukleotide |
WO1998031802A2 (en) * | 1997-01-21 | 1998-07-23 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
EP1007661A2 (de) * | 1997-01-24 | 2000-06-14 | Genetics Institute, Inc. | Sekretierte Proteine und für diese kodierende Polynukleotide |
US5965397A (en) * | 1997-01-31 | 1999-10-12 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
EP0971950A2 (de) * | 1997-02-24 | 2000-01-19 | Genetics Institute, Inc. | Sekretierte proteine und fuer diese kodierende polynukleotide |
US5976837A (en) * | 1997-03-14 | 1999-11-02 | Genetics Institute, Inc. | Secreted proteins and polynucleotides encoding them |
US6080549A (en) * | 1997-04-08 | 2000-06-27 | Northeastern University | Methods and materials for the diagnosis and treatment of schizophrenia and related disorders |
US7803982B2 (en) | 2001-04-20 | 2010-09-28 | The Mount Sinai School Of Medicine Of New York University | T1R3 transgenic animals, cells and related methods |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL59004A0 (en) * | 1978-12-30 | 1980-03-31 | Beecham Group Ltd | Substituted benzamides their preparation and pharmaceutical compositions containing them |
-
1989
- 1989-11-20 DE DE68928137T patent/DE68928137T2/de not_active Expired - Fee Related
- 1989-11-20 AT AT90901227T patent/ATE154636T1/de not_active IP Right Cessation
- 1989-11-20 WO PCT/US1989/005285 patent/WO1990005780A1/en active IP Right Grant
- 1989-11-20 ES ES90901227T patent/ES2104599T3/es not_active Expired - Lifetime
- 1989-11-20 EP EP90901227A patent/EP0447483B1/de not_active Expired - Lifetime
- 1989-11-20 JP JP2501298A patent/JP3018045B2/ja not_active Expired - Lifetime
-
1999
- 1999-02-17 JP JP03846299A patent/JP4122403B2/ja not_active Expired - Lifetime
- 1999-10-21 JP JP29897899A patent/JP3430332B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
WO1990005780A1 (en) | 1990-05-31 |
JP2000083690A (ja) | 2000-03-28 |
EP0447483A4 (en) | 1992-07-08 |
JP3430332B2 (ja) | 2003-07-28 |
ES2104599T3 (es) | 1997-10-16 |
EP0447483A1 (de) | 1991-09-25 |
JPH11285400A (ja) | 1999-10-19 |
DE68928137T2 (de) | 1998-02-19 |
DE68928137D1 (de) | 1997-07-24 |
JPH04506449A (ja) | 1992-11-12 |
EP0447483B1 (de) | 1997-06-18 |
JP3018045B2 (ja) | 2000-03-13 |
JP4122403B2 (ja) | 2008-07-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE68928137D1 (de) | Dopamin-rezeptoren und gene | |
US6692935B1 (en) | Targeted hetero-association of recombinant proteins to multi-functional complexes | |
Löwenadler et al. | A gene fusion system for generating antibodies against short peptides | |
Dabauvalle et al. | Monoclonal antibodies to a Mr 68000 pore complex glycoprotein interfere with nuclear protein uptake in Xenopus oocytes | |
FI961251A (fi) | Ihmisten metabotrooppiset glutamaattireseptorialatyypit(HMR4, HMR6, HMR7)ja niihin liittyvät DNA-yhdisteet | |
NZ331866A (en) | Compounds for immunotherapy and immunodiagnosis of prostate cancer | |
ATE353965T1 (de) | An g-protein gekoppelte rezeptoren und deren verwendungen | |
DK0673420T3 (da) | Mammale receptorer for interleukin 10 (IL-10) | |
KR870010189A (ko) | HTLV-Ⅲgag/ env 유전자 단백질의 발현 및 정제 | |
ATE370233T1 (de) | Zwei menschliche g-protein-gekoppelte rezeptorproteine: ebv-induzierter gpcr2 (ebi-2) und egd-1-ähnlicher gpcr | |
ATE426024T1 (de) | C-c chemokin rezeptor 3: ckr-3 oder eos-l2 | |
WO2006045891A1 (en) | Avidin-like proteins from symbiotic bacteria | |
ATE419358T1 (de) | Gebrauchsverfaheren eines neuen lysyloxidase- verwandten proteins | |
HUP0002472A2 (hu) | Izolált dendritikus sejtmembrán-fehérje gének | |
ES2144399T3 (es) | Clonado del adn de virus de anemia de los pollos. | |
BR0016432A (pt) | Molécula de ácido nucleico isolada, vetor, célula hospedeira, descendentes, sementes ou material celular reproduzìvel, método de produção de um ou mais polipeptìdeo(s), tcmrp isolada, polipeptìdeo isolado, anticorpo, kit de teste, método para produzir um produto quìmico fino, produto quìmico fino, e, uso de um produto quìmico fino ou de polipeptìdeo(s). | |
CA2127117A1 (en) | DNA Encoding a Human Serotonin Receptor (5-HT4B) and Uses Thereof | |
NO902251D0 (no) | Fremstilling av gonorrheiske p1-proteiner og vaksiner. | |
AU7017494A (en) | Purified mammalian flt3 ligands and agonists and antagonists thereof | |
EP1208196A4 (de) | 15571, ein neues gpcr-ähnliches molekül der secretin-ähnlichen familie und dessen verwendungen | |
Seebeck et al. | The cytoskeleton of Trypanosoma brucei-the beauty of simplicity | |
SE8601940D0 (sv) | Preparation of fused proteins, antibodies and processes therefor | |
ATE346919T1 (de) | Nebenhoden-spezifisches rezeptorprotein und dessen verwendung | |
NZ511623A (en) | Methods of identifying antigen gene sequences from Mycoplasma | |
NO178504C (no) | Fr.måte for fr.stilling av minaktivin,DNA-molekyl,gen,vert,prober,preparat som omfatter prober,reagens for lokalisering og defini. av grenser for tumor i histologiske pröver,samt anvendelse av DNA-molekyl,minaktivin og preparat |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |