ATE121755T1 - Deletionsanaloga von magaininpeptiden. - Google Patents

Deletionsanaloga von magaininpeptiden.

Info

Publication number
ATE121755T1
ATE121755T1 AT90901287T AT90901287T ATE121755T1 AT E121755 T1 ATE121755 T1 AT E121755T1 AT 90901287 T AT90901287 T AT 90901287T AT 90901287 T AT90901287 T AT 90901287T AT E121755 T1 ATE121755 T1 AT E121755T1
Authority
AT
Austria
Prior art keywords
amino acid
magainin
deletion
magainin peptides
carboxy
Prior art date
Application number
AT90901287T
Other languages
English (en)
Inventor
Julio H Cuervo
Richard A Houghten
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Application granted granted Critical
Publication of ATE121755T1 publication Critical patent/ATE121755T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT90901287T 1988-12-09 1989-12-05 Deletionsanaloga von magaininpeptiden. ATE121755T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/281,981 US4962277A (en) 1988-12-09 1988-12-09 Deletion analogues of magainin peptides

Publications (1)

Publication Number Publication Date
ATE121755T1 true ATE121755T1 (de) 1995-05-15

Family

ID=23079584

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90901287T ATE121755T1 (de) 1988-12-09 1989-12-05 Deletionsanaloga von magaininpeptiden.

Country Status (9)

Country Link
US (1) US4962277A (de)
EP (1) EP0451190B1 (de)
JP (1) JP2927539B2 (de)
KR (1) KR0149015B1 (de)
AT (1) ATE121755T1 (de)
CA (1) CA2004991C (de)
DE (1) DE68922405T2 (de)
ES (1) ES2071815T3 (de)
WO (1) WO1990006129A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5643876A (en) * 1987-03-04 1997-07-01 The United States Of America As Represented By The Department Of Health And Human Services Biologically active synthetic magainin peptides
SE469132B (sv) * 1989-06-16 1993-05-17 Kabigen Ab Polypeptider och farmaceutisk komposition innehaallande denna
US5912231A (en) * 1989-07-07 1999-06-15 Scripps Clinic And Research Foundation Substitution analogues of magainin peptides
US5045531A (en) * 1989-12-18 1991-09-03 Magainin Sciences Inc. Wound treatment employing biologically active ion channel forming peptides and proteins
US5585353A (en) * 1990-02-02 1996-12-17 The Rockefeller University Antibiotic peptides containing D-amino acids
US5459237A (en) * 1990-02-08 1995-10-17 Magainin Pharmaceuticals Inc. Peptide compositions and uses therefor
US5792831A (en) * 1990-02-08 1998-08-11 Magainin Pharmaceuticals Inc. Analogues of magainin peptides containing D-amino acids
US5221664A (en) * 1990-04-23 1993-06-22 Magainin Pharmaaceuticals Inc. Composition and treatment with biologically active peptides and toxic cations
US5208220A (en) * 1990-06-27 1993-05-04 Magainin Pharmaceuticals, Inc. Composition and treatment with biologically active peptides and antibiotics which inhibit DNA gyrase
JPH07242696A (ja) * 1990-08-10 1995-09-19 Enichem Partecipazioni Spa 植物病原体に対して活性な抗菌性ペプチド、その使用法およびこれに関連するスクリーニング法
US5235038A (en) * 1991-01-22 1993-08-10 Torry Pines Institute For Molecular Studies Deletion and substitution analogues of melittin peptide
AU654714B2 (en) * 1991-04-08 1994-11-17 Magainin Pharmaceuticals, Inc. Novel peptide compositions and uses therefor
US5225399A (en) * 1991-04-15 1993-07-06 The Children's Hospital Of Philadelphia Antimicrobial amphiphilic peptides
US5239059A (en) * 1991-05-10 1993-08-24 The Children's Hospital Of Philadelphia Ion-channel forming peptides
WO1993001723A1 (en) * 1991-07-25 1993-02-04 Magainin Pharmaceuticals, Inc. Prophylaxis and treatment of adverse oral conditions with biologically active peptides
US5885965A (en) * 1991-11-01 1999-03-23 Periodontix, Inc. Anti-fungal D-amino acid histatin-based peptides
WO1994005313A1 (en) * 1992-08-31 1994-03-17 Magainin Pharmaceuticals Inc. Treatment of gynecological malignancies with biologically active peptides
US5424290A (en) * 1992-10-26 1995-06-13 Magainin Pharmaceuticals Inc. Biologically active peptides and uses therefor
WO1994012206A1 (en) * 1992-12-03 1994-06-09 Magainin Pharmaceuticals, Inc. Treatment of dermatological malignancies with biologically active peptides
WO1995000547A1 (en) * 1993-06-22 1995-01-05 E.I. Du Pont De Nemours And Company Antimicrobial composition of a polymer and a peptide forming amphiphilic helices of the magainin-type
EP0725629B1 (de) * 1993-10-25 2000-05-24 The Liposome Company, Inc. Liposomale defensine
US6010861A (en) * 1994-08-03 2000-01-04 Dgi Biotechnologies, Llc Target specific screens and their use for discovering small organic molecular pharmacophores
US5688489A (en) * 1995-09-15 1997-11-18 Resolution Pharmaceuticals, Inc. Non-receptor mediated imaging agents
CN114634553B (zh) * 2022-04-27 2024-03-08 贵州医科大学 阳离子肽c9及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4810777A (en) * 1987-03-04 1989-03-07 The United States Of America As Represented By The Department Of Health And Human Services Antimicrobial compounds

Also Published As

Publication number Publication date
EP0451190A1 (de) 1991-10-16
EP0451190A4 (en) 1992-05-20
JPH04502159A (ja) 1992-04-16
DE68922405T2 (de) 1996-01-04
JP2927539B2 (ja) 1999-07-28
KR910700062A (ko) 1991-03-13
WO1990006129A1 (en) 1990-06-14
US4962277A (en) 1990-10-09
CA2004991C (en) 1999-12-07
CA2004991A1 (en) 1990-06-09
ES2071815T3 (es) 1995-07-01
EP0451190B1 (de) 1995-04-26
DE68922405D1 (de) 1995-06-01
KR0149015B1 (ko) 1998-10-15

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee