ATA151279A - Verfahren zur herstellung von neuen mehrfach halogenierten steroiden - Google Patents

Verfahren zur herstellung von neuen mehrfach halogenierten steroiden

Info

Publication number: ATA151279A
Authority: AT; Austria
Prior art keywords: halogened; steroids; producing new; new multiple; producing
Prior art date: 1976-09-29

Application number

AT151279A

Other languages

English (en)

Other versions

AT363202B (de

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1976-09-29

Filing date

1979-02-28

Publication date

1980-12-15

1979-02-28 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1979-02-28 Priority to AT0151279A priority Critical patent/AT363202B/de

1980-12-15 Publication of ATA151279A publication Critical patent/ATA151279A/de

1981-07-27 Application granted granted Critical

1981-07-27 Publication of AT363202B publication Critical patent/AT363202B/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
- C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
- C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
- C07J71/0015—Oxiranes at position 9(11)

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pain & Pain Management (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Rheumatology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Steroid Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

AT0151279A 1976-09-29 1979-02-28 Verfahren zur herstellung von neuen mehrfach halogenierten steroiden AT363202B (de)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
AT0151279A AT363202B (de)	1976-09-29	1979-02-28	Verfahren zur herstellung von neuen mehrfach halogenierten steroiden

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
LU75903A LU75903A1 (de)	1976-09-29	1976-09-29
AT0691077A AT363197B (de)	1976-09-29	1977-09-28	Verfahren zur herstellung von neuen 9alpha,21-dihalogen-11beta, 17alpha-dihydroxy-6alpha-fluor-16beta-methyl-pregna-1,4-dien-3,20-dion-verbindungen
AT0151279A AT363202B (de)	1976-09-29	1979-02-28	Verfahren zur herstellung von neuen mehrfach halogenierten steroiden

Publications (2)

Publication Number	Publication Date
ATA151279A true ATA151279A (de)	1980-12-15
AT363202B AT363202B (de)	1981-07-27

Family

ID=19728370

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AT0691077A AT363197B (de)	1976-09-29	1977-09-28	Verfahren zur herstellung von neuen 9alpha,21-dihalogen-11beta, 17alpha-dihydroxy-6alpha-fluor-16beta-methyl-pregna-1,4-dien-3,20-dion-verbindungen
AT0151279A AT363202B (de)	1976-09-29	1979-02-28	Verfahren zur herstellung von neuen mehrfach halogenierten steroiden
AT0151379A AT363203B (de)	1976-09-29	1979-02-28	Verfahren zur herstellung von neuen 9alpha,21-

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT0691077A AT363197B (de)	1976-09-29	1977-09-28	Verfahren zur herstellung von neuen 9alpha,21-dihalogen-11beta, 17alpha-dihydroxy-6alpha-fluor-16beta-methyl-pregna-1,4-dien-3,20-dion-verbindungen

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT0151379A AT363203B (de)	1976-09-29	1979-02-28	Verfahren zur herstellung von neuen 9alpha,21-

Country Status (24)

Country	Link
JP (1)	JPS5356652A (de)
AT (3)	AT363197B (de)
AU (1)	AU514200B2 (de)
BE (1)	BE859120A (de)
CA (1)	CA1101410A (de)
CH (9)	CH624967A5 (de)
CY (1)	CY1178A (de)
DD (1)	DD133150A5 (de)
DE (1)	DE2743069C2 (de)
DK (1)	DK146017C (de)
ES (1)	ES462763A1 (de)
FR (1)	FR2366311A1 (de)
GB (1)	GB1563638A (de)
HK (1)	HK16683A (de)
HU (1)	HU175218B (de)
IE (1)	IE46047B1 (de)
IL (1)	IL53012A (de)
KE (1)	KE3258A (de)
LU (1)	LU75903A1 (de)
MY (1)	MY8400092A (de)
NL (1)	NL7710089A (de)
SE (1)	SE436751B (de)
SG (1)	SG3383G (de)
ZA (1)	ZA775800B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL187577C (nl) *	1978-04-05	1991-11-18	Sibla Srl	3-acetoxy-9beta,11beta-epoxy-pregna-1,3,5-trienen, werkwijze voor de bereiding daarvan en werkwijze voor de bereiding van 6alfa-halogeen-pregna-1,4-dieen-3-onen.
DE3227312A1 (de) *	1982-07-19	1984-01-19	Schering AG, 1000 Berlin und 4709 Bergkamen	Neue 6,16-dimethylkortikoide, ihre herstellung und verwendung
EP0523132A1 (de) *	1990-03-27	1993-01-20	Schering Corporation	Verfahren zur dehydrierung von 9-alpha-hydroxy-steroiden
US5972922A (en) *	1990-06-11	1999-10-26	Alcon Laboratories, Inc.	Steroids which inhibit angiogenesis
BR0214520A (pt)	2001-11-29	2006-05-30	Taro Pharmaceuticals Usa Inc	método para a preparação de corticosteróides de 6alfa-fluoro
US11957753B2 (en)	2010-11-22	2024-04-16	Bausch Health Ireland Limited	Pharmaceutical formulations containing corticosteroids for topical administration
US8809307B2 (en)	2010-11-22	2014-08-19	Dow Pharmaceutical Sciences, Inc.	Pharmaceutical formulations containing corticosteroids for topical administration
KR102643849B1 (ko)	2015-06-18	2024-03-07	밸리언트 파마슈티컬즈 노오쓰 아메리카 엘엘씨	건선을 치료하기 위한 코르티코스테로이드 및 레티노이드를 포함하는 국소 조성물

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB898292A (en) *	1959-03-18	1962-06-06	Upjohn Co	Improvements in or relating to steroids and the manufacture thereof
US3644340A (en) *	1970-03-19	1972-02-22	Syntex Corp	Preparation of 21-chloro steroids
US3992422A (en) *	1975-08-14	1976-11-16	Schering Corporation	Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes

1976
- 1976-09-29 LU LU75903A patent/LU75903A1/xx unknown
- 1976-12-09 CH CH1549976A patent/CH624967A5/de not_active IP Right Cessation
1977
- 1977-06-08 SE SE7706673A patent/SE436751B/xx not_active IP Right Cessation
- 1977-06-09 DK DK256977A patent/DK146017C/da not_active IP Right Cessation
- 1977-09-14 NL NL7710089A patent/NL7710089A/xx not_active Application Discontinuation
- 1977-09-24 DE DE2743069A patent/DE2743069C2/de not_active Expired
- 1977-09-26 CH CH1172177A patent/CH632279A5/de not_active IP Right Cessation
- 1977-09-27 CY CY1178A patent/CY1178A/xx unknown
- 1977-09-27 AU AU29148/77A patent/AU514200B2/en not_active Expired
- 1977-09-27 FR FR7729043A patent/FR2366311A1/fr active Granted
- 1977-09-27 DD DD7700201226A patent/DD133150A5/de unknown
- 1977-09-27 CA CA287,560A patent/CA1101410A/en not_active Expired
- 1977-09-27 GB GB40131/77A patent/GB1563638A/en not_active Expired
- 1977-09-28 HU HU77CI1774A patent/HU175218B/hu unknown
- 1977-09-28 BE BE181243A patent/BE859120A/xx not_active IP Right Cessation
- 1977-09-28 ZA ZA00775800A patent/ZA775800B/xx unknown
- 1977-09-28 IL IL53012A patent/IL53012A/xx unknown
- 1977-09-28 AT AT0691077A patent/AT363197B/de not_active IP Right Cessation
- 1977-09-28 IE IE1979/77A patent/IE46047B1/en not_active IP Right Cessation
- 1977-09-29 ES ES462763A patent/ES462763A1/es not_active Expired
- 1977-09-29 JP JP11619377A patent/JPS5356652A/ja active Granted
1979
- 1979-02-28 AT AT0151279A patent/AT363202B/de not_active IP Right Cessation
- 1979-02-28 AT AT0151379A patent/AT363203B/de not_active IP Right Cessation
1980
- 1980-11-18 CH CH853780A patent/CH625808A5/de not_active IP Right Cessation
- 1980-11-18 CH CH853880A patent/CH625809A5/de not_active IP Right Cessation
- 1980-11-18 CH CH853980A patent/CH625810A5/de not_active IP Right Cessation
1981
- 1981-10-26 CH CH683181A patent/CH631999A5/de not_active IP Right Cessation
- 1981-10-26 CH CH683281A patent/CH632000A5/de not_active IP Right Cessation
- 1981-10-26 CH CH683081A patent/CH631998A5/de not_active IP Right Cessation
1982
- 1982-01-06 CH CH4682A patent/CH632521A5/de not_active IP Right Cessation
1983
- 1983-01-20 SG SG33/83A patent/SG3383G/en unknown
- 1983-01-21 KE KE3258A patent/KE3258A/xx unknown
- 1983-05-19 HK HK166/83A patent/HK16683A/xx not_active IP Right Cessation
1984
- 1984-12-30 MY MY92/84A patent/MY8400092A/xx unknown

Also Published As

Publication number	Publication date
HU175218B (hu)	1980-06-28
CH631998A5 (en)	1982-09-15
ES462763A1 (es)	1978-05-16
CH632000A5 (en)	1982-09-15
JPS5356652A (en)	1978-05-23
SE7706673L (sv)	1978-03-30
CA1101410A (en)	1981-05-19
CH632521A5 (en)	1982-10-15
CH625808A5 (en)	1981-10-15
DK146017B (da)	1983-05-24
JPS6214557B2 (de)	1987-04-02
FR2366311B1 (de)	1982-12-03
ZA775800B (en)	1978-08-30
AU514200B2 (en)	1981-01-29
CH625809A5 (en)	1981-10-15
AT363202B (de)	1981-07-27
CH625810A5 (en)	1981-10-15
KE3258A (en)	1983-03-04
CH631999A5 (en)	1982-09-15
NL7710089A (nl)	1978-03-31
AU2914877A (en)	1979-04-05
BE859120A (fr)	1978-03-28
DK146017C (da)	1983-10-24
DD133150A5 (de)	1978-12-13
DK256977A (da)	1978-03-30
CY1178A (en)	1983-06-10
SG3383G (en)	1983-09-09
LU75903A1 (de)	1978-05-16
SE436751B (sv)	1985-01-21
ATA151379A (de)	1980-12-15
IE46047B1 (en)	1983-02-09
HK16683A (en)	1983-05-27
DE2743069A1 (de)	1978-03-30
CH632279A5 (en)	1982-09-30
CH624967A5 (en)	1981-08-31
FR2366311A1 (fr)	1978-04-28
GB1563638A (en)	1980-03-26
ATA691077A (de)	1980-12-15
IL53012A (en)	1982-05-31
IE46047L (en)	1978-03-29
DE2743069C2 (de)	1987-03-05
AT363203B (de)	1981-07-27
IL53012A0 (en)	1977-11-30
MY8400092A (en)	1984-12-31
AT363197B (de)	1981-07-10

Legal Events

Date	Code	Title	Description
1997-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties
1999-08-15	ELA	Expired due to lapse of time

Publication	Publication Date	Title
AT356827B (de)	1980-05-27	Verfahren zur herstellung von neuen spirol- actonen
AT358727B (de)	1980-09-25	Verfahren zur herstellung von neuen cephalos- porinantibiotika
AT356136B (de)	1980-04-10	Verfahren zur herstellung von neuen spiro- hydantoinen
AT359187B (de)	1980-10-27	Verfahren zur herstellung von neuen 7-beta-(2- -oxyimino-2-arylacetamido)-cephalosporinen
AT363478B (de)	1981-08-10	Verfahren zur herstellung von neuen oxepanderivaten
AT370110B (de)	1983-03-10	Verfahren zur herstellung von neuen 4-androsten-3-onen
AT358200B (de)	1980-08-25	Verfahren zur herstellung von neuen steroid- -enolestern
ATA151279A (de)	1980-12-15	Verfahren zur herstellung von neuen mehrfach halogenierten steroiden
AT360185B (de)	1980-12-29	Verfahren zur herstellung von neuen dehydro- digopeptiden
AT361638B (de)	1981-03-25	Verfahren zur herstellung von neuen dimeren indoldihydroindoldionen
AT362786B (de)	1981-06-10	Verfahren zur herstellung von neuen 1-acyl-2-imidazolinen
AT358726B (de)	1980-09-25	Verfahren zur herstellung von neuen cephalos- porinantibiotika
AT360037B (de)	1980-12-10	Verfahren zur herstellung von neuen substi- tuierten phenylguanidinen
AT351191B (de)	1979-07-10	Verfahren zur herstellung von neuen d-homo- steroiden
AT355743B (de)	1980-03-25	Verfahren zur herstellung von neuen kortikoiden
AT364364B (de)	1981-10-12	Verfahren zur herstellung von neuen thiepinen
AT375931B (de)	1984-09-25	Verfahren zur herstellung von neuen aminoalkylfuranderivaten
AT360646B (de)	1981-01-26	Verfahren zur herstellung von neuen cephalos- porinen
AT343623B (de)	1978-06-12	Verfahren zur herstellung von neuen n-alkyl -4-nitro-2- trifluormethyldiphenylaminen
ATA175879A (de)	1980-02-15	Verfahren zur herstellung von neuen antitumorglycosiden
ATA656076A (de)	1979-09-15	Verfahren zur herstellung von neuen d-homo- steroiden
AT355210B (de)	1980-02-25	Verfahren zur herstellung von neuen 1-oxa- dethiacephalosporinen
AT355039B (de)	1980-02-11	Verfahren zur herstellung von neuen veraetherten hydroxy-benzimidazolonen, - benzoxazolonen, -benzoxazinonen,- china- zolinonen und -chinoxazolinonen
AT364367B (de)	1981-10-12	Verfahren zur herstellung von neuen oxepinen
ATA57779A (de)	1980-11-15	Verfahren zur herstellung von neuen 1-oxa- dethiacephalosporinen