AT363591B - Verfahren zur herstellung von lebendimpfstoffen mit einem gehalt an stabilen, hochimmunogenen bakterienmutanten - Google Patents

Verfahren zur herstellung von lebendimpfstoffen mit einem gehalt an stabilen, hochimmunogenen bakterienmutanten

Info

Publication number
AT363591B
AT363591B AT0720178A AT720178A AT363591B AT 363591 B AT363591 B AT 363591B AT 0720178 A AT0720178 A AT 0720178A AT 720178 A AT720178 A AT 720178A AT 363591 B AT363591 B AT 363591B
Authority
AT
Austria
Prior art keywords
immunogenous
vaccinates
bacteria
living
highly
Prior art date
Application number
AT0720178A
Other languages
English (en)
Other versions
ATA720178A (de
Inventor
Klaus Dr Sc Mec Linde
Wolfram Dr Med Vet Schoell
Gudrun Dr Rer Nat Gruenert
Margot Dr Med Vet Michael
Dieter Dr Sc Med Vet Urbaneck
Hans Dr Med Koch
Wilfried Dr Rer Nat Erler
Hans Dr Rer Nat Feist
Klaus-Dieter Dr Rer Flossmann
Helmut Dr Med Vet Hartmann
Horst Vet Rat Dr Habil Meyer
Guenter Dr Habil Steinbach
Original Assignee
Inst Impfstoffe Dessau
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DE19782843295 priority Critical patent/DE2843295A1/de
Application filed by Inst Impfstoffe Dessau filed Critical Inst Impfstoffe Dessau
Priority to AT0720178A priority patent/AT363591B/de
Publication of ATA720178A publication Critical patent/ATA720178A/de
Application granted granted Critical
Publication of AT363591B publication Critical patent/AT363591B/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/025Enterobacteriales, e.g. Enterobacter
    • A61K39/0275Salmonella
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/01Preparation of mutants without inserting foreign genetic material therein; Screening processes therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/522Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/42Salmonella
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT0720178A 1978-10-04 1978-10-06 Verfahren zur herstellung von lebendimpfstoffen mit einem gehalt an stabilen, hochimmunogenen bakterienmutanten AT363591B (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DE19782843295 DE2843295A1 (de) 1978-10-04 1978-10-04 Verfahren zur herstellung stabiler avirulenter und hochimmunogener bakterienmutanten fuer lebendimpfstoffe
AT0720178A AT363591B (de) 1978-10-04 1978-10-06 Verfahren zur herstellung von lebendimpfstoffen mit einem gehalt an stabilen, hochimmunogenen bakterienmutanten

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19782843295 DE2843295A1 (de) 1978-10-04 1978-10-04 Verfahren zur herstellung stabiler avirulenter und hochimmunogener bakterienmutanten fuer lebendimpfstoffe
AT0720178A AT363591B (de) 1978-10-04 1978-10-06 Verfahren zur herstellung von lebendimpfstoffen mit einem gehalt an stabilen, hochimmunogenen bakterienmutanten

Publications (2)

Publication Number Publication Date
ATA720178A ATA720178A (de) 1981-01-15
AT363591B true AT363591B (de) 1981-08-10

Family

ID=37722042

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0720178A AT363591B (de) 1978-10-04 1978-10-06 Verfahren zur herstellung von lebendimpfstoffen mit einem gehalt an stabilen, hochimmunogenen bakterienmutanten

Country Status (2)

Country Link
AT (1) AT363591B (de)
DE (1) DE2843295A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4735801A (en) * 1982-09-07 1988-04-05 Board Of Trustees Of Leland Stanford Jr. University Novel non-reverting salmonella live vaccines
AU554781B2 (en) * 1982-12-30 1986-09-04 Vsesojuzny Gosudarstvenny Nauchno-Kontrolny Institut Veterinarnykh Preparatov And Vsesojuzny Nauchno- Issledovatelsky Veterinarny Institut Ptitsvodstva Live salmonella typhi-murium vaccine
US4764370A (en) * 1984-09-12 1988-08-16 Scripps Clinic And Research Foundation Vaccine utilizing an avirulent strain of Salmonella typhimurium
EP0249449A1 (de) * 1986-06-11 1987-12-16 Enterovax Research Pty. Ltd. Bakterieller Stamm für lebende Impfstoffe
DE3751641D1 (de) * 1986-10-10 1996-02-01 Tad Pharm Werk Salmonella-Lebendimpfstoffe mit Wirtsspezies-angepassten Attenuierungshöhen und antiepidemischer Potenz
DE10299020I2 (de) * 1993-09-04 2007-12-27 Lohmann Animal Health Gmbh Salmonella-Lebendimpfstoff
JP2018526454A (ja) * 2015-09-16 2018-09-13 ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド ブタコレラ菌−ネズミチフス菌ワクチン
US20230141226A1 (en) 2021-11-01 2023-05-11 Boehringer Ingelheim Vetmedica Gmbh Immunogenic gel compositions

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1085956A (en) * 1963-09-10 1967-10-04 Nat Res Dev Improvements relating to vaccines

Also Published As

Publication number Publication date
ATA720178A (de) 1981-01-15
DE2843295C2 (de) 1988-10-13
DE2843295A1 (de) 1980-10-30

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Legal Events

Date Code Title Description
EIH Change in the person of patent owner
ELJ Ceased due to non-payment of the annual fee